JP2005526768A - 炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体 - Google Patents

炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体 Download PDF

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JP2005526768A
JP2005526768A JP2003575886A JP2003575886A JP2005526768A JP 2005526768 A JP2005526768 A JP 2005526768A JP 2003575886 A JP2003575886 A JP 2003575886A JP 2003575886 A JP2003575886 A JP 2003575886A JP 2005526768 A JP2005526768 A JP 2005526768A
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cyclic
saturated
unsaturated
inflammatory
branched
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JP2005526768A5 (fr
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ガルゾン、アーロン
エイブラハム、アイェレット
フィンク、ジョージ
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ファーモス コーポレイション
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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JP2003575886A 2002-03-18 2003-03-16 炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体 Abandoned JP2005526768A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL14873602A IL148736A0 (en) 2002-03-18 2002-03-18 Dexanabinol and dexanabinol analogs which regulate inflammation related genes
PCT/IL2003/000223 WO2003077832A2 (fr) 2002-03-18 2003-03-16 Dexanabinol et analogues de dexanabinol regulant des genes associes a l'inflammation

Publications (2)

Publication Number Publication Date
JP2005526768A true JP2005526768A (ja) 2005-09-08
JP2005526768A5 JP2005526768A5 (fr) 2006-01-26

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ID=27840273

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JP2003575886A Abandoned JP2005526768A (ja) 2002-03-18 2003-03-16 炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体

Country Status (7)

Country Link
EP (1) EP1485083A4 (fr)
JP (1) JP2005526768A (fr)
AU (1) AU2003214608A1 (fr)
CA (1) CA2479676A1 (fr)
IL (1) IL148736A0 (fr)
WO (1) WO2003077832A2 (fr)
ZA (1) ZA200407182B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010532782A (ja) * 2007-07-06 2010-10-14 イー セラピューティクス ピー エル シー メラノーマの治療
JP2013504550A (ja) * 2009-09-10 2013-02-07 イー セラピューティクス ピー エル シー 癌細胞アポトーシス
JP2017031120A (ja) * 2015-08-05 2017-02-09 オリザ油化株式会社 ＴＮＦ−α及びＩＬ−６産生抑制剤及びそれを用いた筋肉炎症抑制剤
WO2018163716A1 (fr) * 2017-03-08 2018-09-13 日清オイリオグループ株式会社 Agent anti-inflammatoire, composition médicinale contre l'inflammation, et composition alimentaire contre l'inflammation

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0326393D0 (en) * 2003-11-12 2003-12-17 Ares Trading Sa Cytokine antagonist molecules
EP1774328A1 (fr) * 2004-07-23 2007-04-18 Novartis AG Biomarqueurs de la polyarthrite rhumatoide (pr)
WO2006024958A2 (fr) * 2004-08-09 2006-03-09 Novimmune S.A. Compositions cannabinoides et procedes d'utilisation correspondants
ES2334924T3 (es) * 2005-03-17 2010-03-17 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de trasplantes.
EP1752149A1 (fr) * 2005-07-29 2007-02-14 Laboratorios Del Dr. Esteve, S.A. CB1 Antagonists ou agonistes inverses comme agents thérapeutiques pour le traitement de l'inflammation impliquant l'expression de gène
US20070104741A1 (en) * 2005-11-07 2007-05-10 Murty Pharmaceuticals, Inc. Delivery of tetrahydrocannabinol
CN101240271B (zh) * 2006-08-28 2012-08-29 长春华普生物技术有限公司 Toll样受体调节性寡核苷酸及其用途
GB0719771D0 (en) * 2007-10-10 2007-11-21 Therapeutics Ltd E Dexanabinol in combination with inhibitors of BRAF or MEK for the treatment of melanoma
GB201207305D0 (en) 2012-04-26 2012-06-13 E Therapeutics Plc Therapy
EP2881111A4 (fr) 2012-08-03 2015-12-16 Univ Ehime Inhibiteur de l'activation d'une cellule immunitaire et son utilisation
WO2017068349A1 (fr) 2015-10-23 2017-04-27 E-Therapeutics Plc Cannabinoïde pour utilisation en immunothérapie

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115245A (en) * 1995-09-11 2002-12-01 Yissum Res Dev Co Tumor necrosis factor inhibiting pharmaceuticals
DE60125541T2 (de) * 2000-06-22 2007-10-11 Pharmos Corp. Neue nicht psychotropische cannabinoide

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010532782A (ja) * 2007-07-06 2010-10-14 イー セラピューティクス ピー エル シー メラノーマの治療
JP2013504550A (ja) * 2009-09-10 2013-02-07 イー セラピューティクス ピー エル シー 癌細胞アポトーシス
JP2015214579A (ja) * 2009-09-10 2015-12-03 イー セラピューティクス ピー エル シーＥ−Ｔｈｅｒａｐｅｕｔｉｃｓ Ｐｌｃ 癌細胞アポトーシス
JP2017031120A (ja) * 2015-08-05 2017-02-09 オリザ油化株式会社 ＴＮＦ−α及びＩＬ−６産生抑制剤及びそれを用いた筋肉炎症抑制剤
WO2018163716A1 (fr) * 2017-03-08 2018-09-13 日清オイリオグループ株式会社 Agent anti-inflammatoire, composition médicinale contre l'inflammation, et composition alimentaire contre l'inflammation

Also Published As

Publication number Publication date
CA2479676A1 (fr) 2003-09-25
WO2003077832A3 (fr) 2003-12-31
EP1485083A4 (fr) 2008-11-19
WO2003077832A2 (fr) 2003-09-25
AU2003214608A1 (en) 2003-09-29
IL148736A0 (en) 2002-09-12
ZA200407182B (en) 2006-02-22
EP1485083A2 (fr) 2004-12-15

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