JP2012131827A5 - - Google Patents

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Publication number: JP2012131827A5
Authority: JP; Japan
Prior art keywords: weight; amount; composition; desoxyascomycin; epi
Prior art date: 2012-03-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP2012077545A

Other languages

English (en)

Japanese (ja)

Other versions

JP2012131827A (ja

JP5599422B2 (ja

Filing date

2012-03-29

Publication date

2013-05-30

1994-10-26 Priority claimed from GB9421612A external-priority patent/GB9421612D0/en

1994-11-04 Priority claimed from GB9422306A external-priority patent/GB9422306D0/en

1995-02-22 Priority claimed from GBGB9503553.1A external-priority patent/GB9503553D0/en

2012-03-29 Application filed filed Critical

2012-07-12 Publication of JP2012131827A publication Critical patent/JP2012131827A/ja

2013-05-30 Publication of JP2012131827A5 publication Critical patent/JP2012131827A5/ja

2014-10-01 Application granted granted Critical

2014-10-01 Publication of JP5599422B2 publication Critical patent/JP5599422B2/ja

2015-10-26 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000000203 mixture Substances 0.000 claims 5
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims 2
GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims 2
150000007524 organic acids Chemical class 0.000 claims 2
KASDHRXLYQOAKZ-OLHLVPFQSA-N pimecrolimus Chemical compound C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C\C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@H](Cl)[C@H](OC)C1 KASDHRXLYQOAKZ-OLHLVPFQSA-N 0.000 claims 2
239000000725 suspension Substances 0.000 claims 2
239000002562 thickening agent Substances 0.000 claims 2
ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 claims 1
239000004264 Petrolatum Substances 0.000 claims 1
229960000541 cetyl alcohol Drugs 0.000 claims 1
BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims 1
GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims 1
239000007764 o/w emulsion Substances 0.000 claims 1
229940055577 oleyl alcohol Drugs 0.000 claims 1
XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 claims 1
235000005985 organic acids Nutrition 0.000 claims 1
239000012188 paraffin wax Substances 0.000 claims 1
239000002245 particle Substances 0.000 claims 1
229940066842 petrolatum Drugs 0.000 claims 1
235000019271 petrolatum Nutrition 0.000 claims 1
229960004063 propylene glycol Drugs 0.000 claims 1
229940075582 sorbic acid Drugs 0.000 claims 1
235000010199 sorbic acid Nutrition 0.000 claims 1
239000004334 sorbic acid Substances 0.000 claims 1
239000003381 stabilizer Substances 0.000 claims 1
229940012831 stearyl alcohol Drugs 0.000 claims 1
239000012049 topical pharmaceutical composition Substances 0.000 claims 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
239000001993 wax Substances 0.000 claims 1

JP2012077545A 1994-10-26 2012-03-29 医薬組成物 Expired - Lifetime JP5599422B2 (ja)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
GB9421612.4		1994-10-26
GB9421612A GB9421612D0 (en)	1994-10-26	1994-10-26	Organic compounds
GB9422306A GB9422306D0 (en)	1994-11-04	1994-11-04	Organic compounds
GB9422306.2		1994-11-04
GBGB9503553.1A GB9503553D0 (en)	1995-02-22	1995-02-22	Organic compounds
GB9503553.1		1995-02-22

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2007047216A Division JP2007145860A (ja)	1994-10-26	2007-02-27	医薬組成物

Publications (3)

Publication Number	Publication Date
JP2012131827A JP2012131827A (ja)	2012-07-12
JP2012131827A5 true JP2012131827A5 (2)	2013-05-30
JP5599422B2 JP5599422B2 (ja)	2014-10-01

Family

ID=27267447

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
JP51431096A Expired - Lifetime JP4155593B2 (ja)	1994-10-26	1995-10-26	医薬組成物
JP2007047216A Withdrawn JP2007145860A (ja)	1994-10-26	2007-02-27	医薬組成物
JP2012077545A Expired - Lifetime JP5599422B2 (ja)	1994-10-26	2012-03-29	医薬組成物

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
JP51431096A Expired - Lifetime JP4155593B2 (ja)	1994-10-26	1995-10-26	医薬組成物
JP2007047216A Withdrawn JP2007145860A (ja)	1994-10-26	2007-02-27	医薬組成物

Country Status (25)

Country	Link
US (1)	US6352998B2 (2)
EP (2)	EP0786986B1 (2)
JP (3)	JP4155593B2 (2)
KR (1)	KR100434682B1 (2)
CN (2)	CN1089233C (2)
AT (2)	ATE299017T1 (2)
AU (1)	AU714254B2 (2)
BR (1)	BR9509530A (2)
CA (1)	CA2200966C (2)
CY (1)	CY2211B1 (2)
CZ (1)	CZ289773B6 (2)
DE (3)	DE69534306T2 (2)
DK (2)	DK1147766T3 (2)
ES (2)	ES2173978T3 (2)
FI (2)	FI119754B (2)
GB (1)	GB2308546B (2)
HU (1)	HU223840B1 (2)
MX (1)	MX9702699A (2)
NO (2)	NO316963B1 (2)
NZ (2)	NZ295170A (2)
PL (1)	PL184750B1 (2)
PT (2)	PT1147766E (2)
SI (1)	SI0786986T1 (2)
SK (1)	SK284591B6 (2)
WO (1)	WO1996013249A1 (2)

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GB0307866D0 (en) *	2003-04-04	2003-05-14	Novartis Ag	Pharmaceutical composition
GB0307869D0 (en) *	2003-04-04	2003-05-14	Novartis Ag	Pharmaceutical composition
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GB0408070D0 (en) *	2004-04-08	2004-05-12	Novartis Ag	Pharmaceutical formulations
ES2389443T3 (es) *	2004-04-08	2012-10-26	Meda Pharma S.À.R.L.	Composición de espuma de pimecrolimus que contiene hexilenglicol, opcionalmente alcohol de oleílo, dimetilisosorbida y/o triglicéridos de cadena media
GB0508827D0 (en) *	2005-04-29	2005-06-08	Novartis Ag	Cosmeceutical composition
US9205080B2 (en)	2006-11-16	2015-12-08	Transderm, Inc.	Methods of treating keratin hyperproliferation disorders using mTOR inhibitors
EP2016935A1 (en) *	2007-07-09	2009-01-21	Intendis GmbH	Pharmaceutical composition for topical application of poorly soluble compounds
CN101288643B (zh) *	2008-06-17	2012-11-14	杨喜鸿	含有他克莫司的凝胶剂组合物及其制备方法和药物应用
EP2308468A1 (en) *	2009-10-08	2011-04-13	Novaliq GmbH	Novel pharmaceutical composition comprising a macrolide immunosuppressant drug
GB0917816D0 (en)	2009-10-12	2009-11-25	Biotica Tech Ltd	Novel compounds and methods for their production
GB0917817D0 (en)	2009-10-12	2009-11-25	Biotica Tech Ltd	Novel compounds and methods for their production
EP2366378A1 (en)	2010-03-01	2011-09-21	Dexcel Pharma Technologies Ltd.	Sustained-release donepezil formulations
JP5674786B2 (ja) *	2010-07-23	2015-02-25	マルホ株式会社	タクロリムスを含有する水中油型クリーム状組成物
WO2012011192A1 (ja) *	2010-07-23	2012-01-26	マルホ株式会社	タクロリムスを含有する水中油型クリーム状組成物
CN102552253A (zh) *	2012-01-17	2012-07-11	唯美度科技（北京）有限公司	一种祛痘用皮肤外用剂
JP6084579B2 (ja) *	2012-01-25	2017-02-22	マルホ株式会社	タクロリムスを含有する水中油型クリーム状組成物
WO2014117035A1 (en) *	2013-01-24	2014-07-31	Transderm, Inc.	COMPOSITIONS FOR TRANSDERMAL DELIVERY OF mTOR INHIBITORS
MX367121B (es) *	2013-08-02	2019-08-06	Laboratorio Raam De Sahuayo S A De C V	Composición sólida estable de inmunosupresores.
DE102013222164A1 (de) *	2013-10-31	2015-04-30	Deb Ip Limited	Stabilisierte multiple Emulsionen als Hautschutzprodukt
US10765665B2 (en)	2015-11-24	2020-09-08	Melin Jeffrey	Composition comprising combination of rapamycin and an activator of AMP kinase and use thereof for treating diseases
CN105663027B (zh) *	2016-04-01	2018-12-18	中国人民解放军广州军区武汉总医院	西罗莫司外用制剂、其制备方法及用途
JP6932180B2 (ja) *	2016-04-04	2021-09-08	エムシー２・セラピューティクス・リミテッドＭＣ２ＴｈｅｒａｐｅｕｔｉｃｓＬｉｍｉｔｅｄ	タクロリムスを含む局所組成物
JP7108631B2 (ja)	2017-01-06	2022-07-28	パルヴェラセラピューティクス、インク．	ｍＴＯＲ阻害剤の無水組成物およびその使用方法
KR101973065B1 (ko)	2017-09-13	2019-04-26	(주)썬테크	풍력 발전기 및 풍력 발전기의 블레이드 팁
EP3542788A1 (en)	2018-03-19	2019-09-25	MC2 Therapeutics Limited	Topical composition comprising calcipotriol and betamethasone dipropionate
KR101995905B1 (ko)	2018-03-27	2019-07-04	(주)썬테크	풍력 발전기 및 풍력 발전기의 발전모터
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1995
- 1995-10-26 AT AT01117396T patent/ATE299017T1/de active
- 1995-10-26 KR KR1019970702752A patent/KR100434682B1/ko not_active Expired - Lifetime
- 1995-10-26 EP EP95936554A patent/EP0786986B1/en not_active Expired - Lifetime
- 1995-10-26 SK SK520-97A patent/SK284591B6/sk not_active IP Right Cessation
- 1995-10-26 AU AU38451/95A patent/AU714254B2/en not_active Expired
- 1995-10-26 BR BR9509530A patent/BR9509530A/pt not_active Application Discontinuation
- 1995-10-26 JP JP51431096A patent/JP4155593B2/ja not_active Expired - Lifetime
- 1995-10-26 DE DE69534306T patent/DE69534306T2/de not_active Expired - Lifetime
- 1995-10-26 ES ES95936554T patent/ES2173978T3/es not_active Expired - Lifetime
- 1995-10-26 EP EP01117396A patent/EP1147766B1/en not_active Expired - Lifetime
- 1995-10-26 CZ CZ19971232A patent/CZ289773B6/cs not_active IP Right Cessation
- 1995-10-26 CN CN95195900A patent/CN1089233C/zh not_active Expired - Lifetime
- 1995-10-26 PT PT01117396T patent/PT1147766E/pt unknown
- 1995-10-26 SI SI9530589T patent/SI0786986T1/xx unknown
- 1995-10-26 GB GB9707484A patent/GB2308546B/en not_active Expired - Lifetime
- 1995-10-26 DE DE69525957T patent/DE69525957T2/de not_active Expired - Lifetime
- 1995-10-26 ES ES01117396T patent/ES2243369T3/es not_active Expired - Lifetime
- 1995-10-26 PT PT95936554T patent/PT786986E/pt unknown
- 1995-10-26 WO PCT/EP1995/004208 patent/WO1996013249A1/en not_active Ceased
- 1995-10-26 PL PL95319599A patent/PL184750B1/pl unknown
- 1995-10-26 NZ NZ295170A patent/NZ295170A/xx not_active IP Right Cessation
- 1995-10-26 CN CNB021243700A patent/CN100335063C/zh not_active Expired - Lifetime
- 1995-10-26 MX MX9702699A patent/MX9702699A/es active IP Right Grant
- 1995-10-26 AT AT95936554T patent/ATE214593T1/de active
- 1995-10-26 CA CA002200966A patent/CA2200966C/en not_active Expired - Lifetime
- 1995-10-26 HU HU9701928A patent/HU223840B1/hu active IP Right Revival
- 1995-10-26 NZ NZ331824A patent/NZ331824A/xx not_active IP Right Cessation
- 1995-10-26 DK DK01117396T patent/DK1147766T3/da active
- 1995-10-26 DK DK95936554T patent/DK0786986T3/da active
- 1995-10-26 DE DE19581804T patent/DE19581804T1/de not_active Ceased
1997
- 1997-03-11 FI FI971018A patent/FI119754B/fi not_active IP Right Cessation
- 1997-04-25 NO NO19971951A patent/NO316963B1/no not_active IP Right Cessation
2000
- 2000-12-01 CY CY0000067A patent/CY2211B1/xx unknown
2001
- 2001-01-23 US US09/767,656 patent/US6352998B2/en not_active Expired - Lifetime
2004
- 2004-09-08 NO NO2004005C patent/NO2004005I2/no unknown
2007
- 2007-02-27 JP JP2007047216A patent/JP2007145860A/ja not_active Withdrawn
- 2007-12-28 FI FI20071025A patent/FI119755B/fi not_active IP Right Cessation
2012
- 2012-03-29 JP JP2012077545A patent/JP5599422B2/ja not_active Expired - Lifetime

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