JP2012504393A5 - - Google Patents
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- JP2012504393A5 JP2012504393A5 JP2011529472A JP2011529472A JP2012504393A5 JP 2012504393 A5 JP2012504393 A5 JP 2012504393A5 JP 2011529472 A JP2011529472 A JP 2011529472A JP 2011529472 A JP2011529472 A JP 2011529472A JP 2012504393 A5 JP2012504393 A5 JP 2012504393A5
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- Japan
- Prior art keywords
- peptide
- cell
- seq
- tumor
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 35
- 210000004027 cell Anatomy 0.000 claims 13
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 239000013604 expression vector Substances 0.000 claims 6
- 208000005017 glioblastoma Diseases 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 102100028743 CAP-Gly domain-containing linker protein 2 Human genes 0.000 claims 3
- 102100024074 Dystrobrevin alpha Human genes 0.000 claims 3
- 206010018338 Glioma Diseases 0.000 claims 3
- 101000767059 Homo sapiens CAP-Gly domain-containing linker protein 2 Proteins 0.000 claims 3
- 101001053689 Homo sapiens Dystrobrevin alpha Proteins 0.000 claims 3
- 101001108364 Homo sapiens Neuronal cell adhesion molecule Proteins 0.000 claims 3
- 101000633503 Homo sapiens Nuclear receptor subfamily 2 group E member 1 Proteins 0.000 claims 3
- 101000600766 Homo sapiens Podoplanin Proteins 0.000 claims 3
- 208000000172 Medulloblastoma Diseases 0.000 claims 3
- 206010029260 Neuroblastoma Diseases 0.000 claims 3
- 102100021852 Neuronal cell adhesion molecule Human genes 0.000 claims 3
- 102100029534 Nuclear receptor subfamily 2 group E member 1 Human genes 0.000 claims 3
- 102100037265 Podoplanin Human genes 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 239000003550 marker Substances 0.000 claims 3
- 206010003571 Astrocytoma Diseases 0.000 claims 2
- 206010014967 Ependymoma Diseases 0.000 claims 2
- 208000003098 Ganglion Cysts Diseases 0.000 claims 2
- 208000032612 Glial tumor Diseases 0.000 claims 2
- 108700018351 Major Histocompatibility Complex Proteins 0.000 claims 2
- 201000000582 Retinoblastoma Diseases 0.000 claims 2
- 208000005400 Synovial Cyst Diseases 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 210000001072 colon Anatomy 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000014509 gene expression Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 208000027831 neuroepithelial neoplasm Diseases 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 208000029340 primitive neuroectodermal tumor Diseases 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 claims 2
- 102100021663 Baculoviral IAP repeat-containing protein 5 Human genes 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 102100028757 Chondroitin sulfate proteoglycan 4 Human genes 0.000 claims 1
- 208000004139 Choroid Plexus Neoplasms Diseases 0.000 claims 1
- 208000030808 Clear cell renal carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 201000004066 Ganglioglioma Diseases 0.000 claims 1
- 201000010915 Glioblastoma multiforme Diseases 0.000 claims 1
- 102000006354 HLA-DR Antigens Human genes 0.000 claims 1
- 108010058597 HLA-DR Antigens Proteins 0.000 claims 1
- 101000916489 Homo sapiens Chondroitin sulfate proteoglycan 4 Proteins 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 1
- 208000033383 Neuroendocrine tumor of pancreas Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 201000010133 Oligodendroglioma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 208000007641 Pinealoma Diseases 0.000 claims 1
- 206010057846 Primitive neuroectodermal tumour Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 108010002687 Survivin Proteins 0.000 claims 1
- 206010043276 Teratoma Diseases 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 201000005476 astroblastoma Diseases 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 201000007455 central nervous system cancer Diseases 0.000 claims 1
- 208000025997 central nervous system neoplasm Diseases 0.000 claims 1
- 230000002490 cerebral effect Effects 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000001886 ciliary effect Effects 0.000 claims 1
- 206010073251 clear cell renal cell carcinoma Diseases 0.000 claims 1
- 238000004040 coloring Methods 0.000 claims 1
- 230000009260 cross reactivity Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 208000010932 epithelial neoplasm Diseases 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 210000004602 germ cell Anatomy 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 208000032839 leukemia Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 210000001161 mammalian embryo Anatomy 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 201000004058 mixed glioma Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 201000011330 nonpapillary renal cell carcinoma Diseases 0.000 claims 1
- 230000008520 organization Effects 0.000 claims 1
- 230000002018 overexpression Effects 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 208000023958 prostate neoplasm Diseases 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 210000003491 skin Anatomy 0.000 claims 1
- 206010041823 squamous cell carcinoma Diseases 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08017305.7 | 2008-10-01 | ||
| EP20080017305 EP2172211B1 (en) | 2008-10-01 | 2008-10-01 | Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers |
| EP08017921.1A EP2172212B1 (en) | 2008-10-01 | 2008-10-13 | Novel immunotherapy against several tumors including neuronal and brain tumors |
| EP08017921.1 | 2008-10-13 | ||
| US10592808P | 2008-10-16 | 2008-10-16 | |
| US61/105,928 | 2008-10-16 | ||
| PCT/EP2009/006980 WO2010037514A2 (en) | 2008-10-01 | 2009-09-28 | Novel immunotherapy against several tumors including neuronal and brain tumors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014126001A Division JP5883476B2 (ja) | 2008-10-01 | 2014-06-19 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012504393A JP2012504393A (ja) | 2012-02-23 |
| JP2012504393A5 true JP2012504393A5 (2) | 2013-05-23 |
| JP5855940B2 JP5855940B2 (ja) | 2016-02-09 |
Family
ID=40342382
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011529471A Expired - Fee Related JP5753783B2 (ja) | 2008-10-01 | 2009-09-28 | 神経膠芽細胞腫(gbm)およびその他の癌の治療に用いる腫瘍関連ペプチド組成物と関連抗癌ワクチン |
| JP2011529472A Expired - Fee Related JP5855940B2 (ja) | 2008-10-01 | 2009-09-28 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2014126001A Expired - Fee Related JP5883476B2 (ja) | 2008-10-01 | 2014-06-19 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2015200021A Expired - Fee Related JP6150859B2 (ja) | 2008-10-01 | 2015-10-08 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016021002A Expired - Fee Related JP6214066B2 (ja) | 2008-10-01 | 2016-02-05 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136517A Expired - Fee Related JP6294913B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136516A Pending JP2017029135A (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136519A Expired - Fee Related JP6297632B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136518A Expired - Fee Related JP6294914B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136515A Expired - Fee Related JP6367266B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011529471A Expired - Fee Related JP5753783B2 (ja) | 2008-10-01 | 2009-09-28 | 神経膠芽細胞腫(gbm)およびその他の癌の治療に用いる腫瘍関連ペプチド組成物と関連抗癌ワクチン |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014126001A Expired - Fee Related JP5883476B2 (ja) | 2008-10-01 | 2014-06-19 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2015200021A Expired - Fee Related JP6150859B2 (ja) | 2008-10-01 | 2015-10-08 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016021002A Expired - Fee Related JP6214066B2 (ja) | 2008-10-01 | 2016-02-05 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136517A Expired - Fee Related JP6294913B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136516A Pending JP2017029135A (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136519A Expired - Fee Related JP6297632B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136518A Expired - Fee Related JP6294914B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
| JP2016136515A Expired - Fee Related JP6367266B2 (ja) | 2008-10-01 | 2016-07-11 | 神経細胞性脳腫瘍など数種の腫瘍に対する新規免疫療法 |
Country Status (24)
| Country | Link |
|---|---|
| US (19) | US8318677B2 (2) |
| EP (12) | EP2172211B1 (2) |
| JP (10) | JP5753783B2 (2) |
| KR (6) | KR102392070B1 (2) |
| CN (3) | CN106986919A (2) |
| AU (2) | AU2009300088B2 (2) |
| BR (2) | BRPI0920791B8 (2) |
| CA (9) | CA2936870C (2) |
| CY (11) | CY1116302T1 (2) |
| DK (12) | DK2172211T3 (2) |
| EA (3) | EA023378B1 (2) |
| ES (12) | ES2536465T3 (2) |
| HR (12) | HRP20201025T8 (2) |
| HU (11) | HUE031030T2 (2) |
| LT (10) | LT2172212T (2) |
| MX (3) | MX2011003540A (2) |
| NZ (4) | NZ603016A (2) |
| PL (12) | PL2172211T3 (2) |
| PT (12) | PT2172211E (2) |
| RS (12) | RS53782B1 (2) |
| SI (12) | SI2172211T1 (2) |
| TR (2) | TR201900852T4 (2) |
| UA (3) | UA103202C2 (2) |
| WO (2) | WO2010037514A2 (2) |
Families Citing this family (121)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006023598A2 (en) | 2004-08-19 | 2006-03-02 | University Of Maryland, Baltimore | Prostate-specific antigen-derived mhc class ii-restricted peptides and their use in vaccines to treat or prevent prostate cancer |
| WO2012079878A2 (en) * | 2010-12-14 | 2012-06-21 | Immatics Biotechnologies Gmbh | Hla-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
| WO2006034334A2 (en) | 2004-09-21 | 2006-03-30 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Peptide analogs capable of enhancing stimulation of a glioma-specific ctl response |
| BRPI0813621A2 (pt) * | 2007-07-27 | 2017-05-09 | Immatics Biotechnologies Gmbh | imunoterapia contra tumores neuronais e cerebrais |
| PT2113253E (pt) * | 2008-04-30 | 2010-06-15 | Immatics Biotechnologies Gmbh | Formulações novas de peptídeos associados a tumores que se ligam a moléculas de classe i ou ii do antígeno leucocitário humano (hla) para vacinas |
| SI2119726T2 (en) | 2008-05-14 | 2018-03-30 | Immatics Biotechnologies Gmbh | New and powerful Class II MHC peptides derived from survivin and neurocane |
| PL2172211T3 (pl) | 2008-10-01 | 2015-05-29 | Immatics Biotechnologies Gmbh | Kompozycja związanych z guzem peptydów i związana z tym szczepionka przeciwrakowa do leczenia glejaka (GBM) i innych rodzajów raka |
| TW201124530A (en) * | 2009-12-01 | 2011-07-16 | Oncotherapy Science Inc | IMP-3 oligopeptides and vaccines including the same |
| SE535982C2 (sv) * | 2009-12-15 | 2013-03-19 | Theravac Pharmaceuticals Ab | Ett nytt vaccin som angriper tumörkärl som ett effektivt redskap i tumörterapi |
| AU2015200751B2 (en) * | 2010-03-19 | 2016-11-10 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| EP2608799B1 (en) * | 2010-08-24 | 2018-12-12 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Interleukin-13 receptor alpha 2 peptide-based brain cancer vaccines |
| WO2012075490A2 (en) * | 2010-12-03 | 2012-06-07 | Duke University | Anti-podoplanin antibodies and methods of use |
| US20140154269A1 (en) * | 2011-04-26 | 2014-06-05 | The Methodist Hospital Research Institute | Targeted nanovectors and their use for treatment of brain tumors |
| US9889209B2 (en) | 2011-09-14 | 2018-02-13 | Northwestern University | Nanoconjugates able to cross the blood-brain barrier |
| GB201120779D0 (en) * | 2011-12-02 | 2012-01-11 | Immodulon Therapeutics Ltd | Cancer therapy |
| BR112014017833A2 (pt) | 2012-01-20 | 2021-03-23 | Dennis Brown | Uso de hexitóis substituídos incluindo dianidrogalactitol e análogos para tratar doença neoplástica e células-tronco de câncer incluindo glioblastoma multiforme e meduloblastoma |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| CN103372217B (zh) * | 2012-04-28 | 2014-12-10 | 中国科学院深圳先进技术研究院 | 聚合物纳米载体制剂及其制备方法和应用 |
| DK3536334T3 (da) * | 2012-05-16 | 2021-09-13 | Stemline Therapeutics Inc | Cancer stamcelle målrettede cancer vacciner |
| CN112587671A (zh) * | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| PL3456339T3 (pl) | 2013-08-05 | 2022-03-21 | Immatics Biotechnologies Gmbh | Nowa immunoterapia przeciwko szeregu nowotworom, takim jak rak płuc, w tym nsclc |
| TWI775117B (zh) * | 2013-08-05 | 2022-08-21 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(二) |
| GB201319446D0 (en) * | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
| MX2019013161A (es) * | 2013-11-04 | 2020-02-03 | Immatics Biotechnologies Gmbh | Inmunoterapia personalizada contra diversos tumores cerebrales y neuronales. |
| CN104698059B (zh) * | 2013-12-04 | 2017-07-21 | 苏州中赢医疗科技有限公司 | 一种脑胶质瘤肿瘤标志物及其应用 |
| GB201322725D0 (en) | 2013-12-20 | 2014-02-05 | Immodulon Therapeutics Ltd | Cancer therapy |
| WO2015105955A1 (en) | 2014-01-08 | 2015-07-16 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| KR101503341B1 (ko) * | 2014-03-12 | 2015-03-18 | 국립암센터 | 자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법 |
| NZ725201A (en) | 2014-04-25 | 2018-05-25 | Bluebird Bio Inc | Improved methods for manufacturing adoptive cell therapies |
| LT3134432T (lt) | 2014-04-25 | 2020-04-10 | Bluebird Bio, Inc. | Mnd promotorius chimerinių antigenų receptoriams |
| WO2015182668A1 (ja) * | 2014-05-28 | 2015-12-03 | 学校法人東京女子医科大学 | 膠芽腫の予測方法 |
| JP2015227292A (ja) * | 2014-05-30 | 2015-12-17 | 国立大学法人高知大学 | 膵がん細胞浸潤転移抑制ワクチン |
| SI3151672T1 (sl) | 2014-06-06 | 2021-03-31 | Bluebird Bio, Inc. | Izboljšani T-celični sestavki |
| JP6366379B2 (ja) * | 2014-06-20 | 2018-08-01 | キヤノン株式会社 | 被検体情報取得装置 |
| MX2017001079A (es) | 2014-07-24 | 2017-09-12 | Bluebird Bio Inc | Receptores de antígeno quiméricos de antígeno de maduración de células b (bcma). |
| WO2016070928A1 (en) * | 2014-11-06 | 2016-05-12 | Orphan Synergy Europe - Pharma | Therapeutic multi-peptides t specific immune therapy for treatment of brain metastasis |
| EA036379B1 (ru) | 2014-12-12 | 2020-11-02 | Блубёрд Био, Инк. | Химерные антигенные рецепторы к bcma |
| KR102643923B1 (ko) | 2014-12-23 | 2024-03-05 | 이매틱스 바이오테크놀로지스 게엠베하 | 간세포 암종(hcc) 및 기타 암들에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 펩티드의 조합 |
| GB201501017D0 (en) * | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| GB201423361D0 (en) * | 2014-12-30 | 2015-02-11 | Immatics Biotechnologies Gmbh | Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides |
| TWI755158B (zh) | 2015-03-17 | 2022-02-11 | 德商英麥提克生物技術股份有限公司 | 用於抗胰臟癌與其他癌症的免疫治療的新穎胜肽及胜肽的組合 |
| GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| PH12021550910A1 (en) * | 2015-05-06 | 2022-03-07 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (crc) and other cancers |
| GB201507719D0 (en) * | 2015-05-06 | 2015-06-17 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers |
| NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
| WO2016200787A2 (en) | 2015-06-09 | 2016-12-15 | The Board Of Regents Of The University Of Oklahoma | Compositions and treatments for haemophilus influenzae |
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| GB201021289D0 (en) | 2010-12-15 | 2011-01-26 | Immatics Biotechnologies Gmbh | Novel biomarkers for a prediction of the outcome of an immunotherapy against cancer |
| WO2015181756A1 (en) * | 2014-05-28 | 2015-12-03 | Nono Inc. | Chloride salt of tat-nr2b9c |
| KR20180135481A (ko) | 2016-04-21 | 2018-12-20 | 이매틱스 바이오테크놀로지스 게엠베하 | 흑색종 및 기타 암에 대한 면역요법 |
| WO2019051001A1 (en) * | 2017-09-06 | 2019-03-14 | California Institute Of Technology | SIGNALING AND BIFUNCTIONAL RECEPTORS HAVING ANTIGENS (SABR) |
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