JP2013507603A5 - - Google Patents

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Publication number
JP2013507603A5
JP2013507603A5 JP2012532458A JP2012532458A JP2013507603A5 JP 2013507603 A5 JP2013507603 A5 JP 2013507603A5 JP 2012532458 A JP2012532458 A JP 2012532458A JP 2012532458 A JP2012532458 A JP 2012532458A JP 2013507603 A5 JP2013507603 A5 JP 2013507603A5
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JP
Japan
Prior art keywords
recombinant
peptide
sample
fraction
signature
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012532458A
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English (en)
Japanese (ja)
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JP2013507603A (ja
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Publication date
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Priority claimed from PCT/DK2010/050258 external-priority patent/WO2011042027A2/en
Publication of JP2013507603A publication Critical patent/JP2013507603A/ja
Publication of JP2013507603A5 publication Critical patent/JP2013507603A5/ja
Pending legal-status Critical Current

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JP2012532458A 2009-10-09 2010-10-07 署名ペプチドおよび質量分析による混合物中の個々の組換えタンパク質の多重定量化 Pending JP2013507603A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200901112 2009-10-09
DKPA200901112 2009-10-09
US25623209P 2009-10-29 2009-10-29
US61/256,232 2009-10-29
PCT/DK2010/050258 WO2011042027A2 (en) 2009-10-09 2010-10-07 Multiplex quantitation of individual recombinant proteins in a mixture by signature peptides and mass spectrometry

Publications (2)

Publication Number Publication Date
JP2013507603A JP2013507603A (ja) 2013-03-04
JP2013507603A5 true JP2013507603A5 (2) 2013-11-21

Family

ID=42166454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012532458A Pending JP2013507603A (ja) 2009-10-09 2010-10-07 署名ペプチドおよび質量分析による混合物中の個々の組換えタンパク質の多重定量化

Country Status (14)

Country Link
US (1) US20120264155A1 (2)
EP (1) EP2486411A2 (2)
JP (1) JP2013507603A (2)
KR (1) KR20120100982A (2)
CN (1) CN102687020A (2)
AU (1) AU2010305150A1 (2)
BR (1) BR112012007815A2 (2)
CA (1) CA2776508A1 (2)
IL (1) IL218821A0 (2)
IN (1) IN2012DN03911A (2)
MX (1) MX2012003538A (2)
RU (1) RU2012118620A (2)
WO (1) WO2011042027A2 (2)
ZA (1) ZA201202431B (2)

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KR101992502B1 (ko) * 2011-05-12 2019-06-24 제넨테크, 인크. 프레임워크 시그너처 펩티드를 사용하여 동물 샘플에서 치료 항체를 검출하기 위한 다중 반응 모니터링 lc-ms/ms 방법
WO2013019714A1 (en) 2011-07-29 2013-02-07 The Trustees Of Columbia University In The City Of New York Mems affinity sensor for continuous monitoring of analytes
WO2016022696A1 (en) 2014-08-05 2016-02-11 The Trustees Of Columbia University In The City Of New York Method of isolating aptamers for minimal residual disease detection
WO2016145390A1 (en) 2015-03-12 2016-09-15 Mars, Incorporated Ultra high resolution mass spectrometry and methods of using the same
US10794916B2 (en) 2015-05-06 2020-10-06 Momenta Pharmaceuticals, Inc. Methods of glycoprotein analysis
CN105242050A (zh) * 2015-09-16 2016-01-13 同济大学 一种不同生理或病理条件下整体蛋白质的定量分析方法
CN105218671A (zh) * 2015-09-29 2016-01-06 李艳华 一种传染病病原体全人源化抗体的制备方法
GB201603291D0 (en) * 2016-02-25 2016-04-13 Binding Site Group The Ltd Antibodies
US20170315132A1 (en) * 2016-03-25 2017-11-02 Genentech, Inc. Multiplexed total antibody and antibody-conjugated drug quantification assay
EP3465221B1 (en) 2016-05-27 2020-07-22 H. Hoffnabb-La Roche Ag Bioanalytical method for the characterization of site-specific antibody-drug conjugates
CN107525934A (zh) * 2016-06-21 2017-12-29 张效龙 一种测定血液中抗体氨基酸序列的方法
WO2018035350A1 (en) * 2016-08-17 2018-02-22 Momenta Pharmaceuticals, Inc. Glycan oxonium ion profiling of glycosylated proteins
CN108072728A (zh) * 2016-11-16 2018-05-25 中国科学院大连化学物理研究所 一种基于数据依赖性质谱扫描模式的谱图库建立方法及其应用
CN108956789A (zh) * 2017-05-17 2018-12-07 中国科学院大连化学物理研究所 一种血清中免疫球蛋白g糖肽的绝对定量分析方法
SG11202000727SA (en) * 2017-08-01 2020-02-27 Amgen Inc Systems and methods for real time preparation of a polypeptide sample for analysis with mass spectrometry
US10615016B2 (en) * 2017-09-07 2020-04-07 Thermo Fisher Scientific (Bremen) Gmbh Determining isotope ratios using mass spectrometry
CN108169397B (zh) * 2017-11-30 2019-11-15 中国农业科学院北京畜牧兽医研究所 一种相对定量分析肉鸡谷胱甘肽s转移酶gsta2的方法
CN108226516B (zh) * 2017-11-30 2020-05-19 中国农业科学院北京畜牧兽医研究所 一种相对定量分析肉鸡脂肪酸去饱和酶fads1的方法
CN109900815B (zh) * 2017-12-08 2021-06-29 中国科学院大连化学物理研究所 血清中IgG糖肽的绝对定量分析
CN112135839A (zh) * 2018-01-31 2020-12-25 瑞泽恩制药公司 作为治疗性单克隆抗体上的新酸性翻译后修饰的葡糖醛酸化
JP7205077B2 (ja) * 2018-05-10 2023-01-17 株式会社島津製作所 分析方法、処理装置、分析装置およびプログラム
CN110824096B (zh) * 2018-08-13 2022-11-29 齐鲁制药有限公司 一种蛋白错配二硫键的分析方法
CN110007019A (zh) * 2019-03-29 2019-07-12 绿城农科检测技术有限公司 一种同时定量检测母乳中三种抗体含量的方法
GB201910697D0 (en) * 2019-07-26 2019-09-11 Binding Site Group Ltd Lonisation control
US20230089196A1 (en) 2020-02-21 2023-03-23 Genmab B.V. Methods for the quantification of glycoproteins
CN111551739A (zh) * 2020-04-27 2020-08-18 杭州璞湃科技有限公司 一种免疫球蛋白a和免疫球蛋白a1的检测方法及其试剂盒
WO2021258114A1 (en) * 2020-06-18 2021-12-23 Northwestern University Process for direct readout of immunoglobulins
JP7478040B2 (ja) * 2020-06-25 2024-05-02 シスメックス株式会社 Ａβペプチドの測定方法及びその方法に用いられる試薬組成物
CN111766323B (zh) * 2020-07-10 2022-06-14 中国检验检疫科学研究院 一种用于检测骆驼奶中掺入牛奶的特征肽组合及方法
CN113933409B (zh) * 2021-09-14 2023-11-14 上海中科新生命生物科技有限公司 基于液相色谱-质谱检测血清中特瑞普利单抗的方法
DE102022115561B4 (de) * 2022-06-22 2024-06-13 Bruker Daltonics GmbH & Co. KG Massenspektrometrische Bestimmung der Zelltoxizität
CN118221778A (zh) * 2024-04-25 2024-06-21 烟台大学 拟穴青蟹Scyreprocin蛋白的特征肽段及其在雌雄鉴别方面的应用
CN120399082B (zh) * 2025-07-04 2025-08-26 北京溯本源和生物科技有限公司 一种用于检测猫Cys-C蛋白的单克隆抗体组合及应用

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JP2006300758A (ja) * 2005-04-21 2006-11-02 Apro Life Science Institute Inc 内部標準ペプチドを用いて生体由来試料に含まれる標的タンパク質を定量する方法
EP2314619A1 (en) 2005-12-05 2011-04-27 Symphogen A/S Anti-orthopoxvirus recombinant polyclonal antibody
JP2009528828A (ja) 2006-03-06 2009-08-13 シムフォゲン・アクティーゼルスカブ 消化器多核体ウイルス感染症の治療のための組み換えポリクローナル抗体
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