JP2014040431A5 - - Google Patents
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- Publication number
- JP2014040431A5 JP2014040431A5 JP2013194484A JP2013194484A JP2014040431A5 JP 2014040431 A5 JP2014040431 A5 JP 2014040431A5 JP 2013194484 A JP2013194484 A JP 2013194484A JP 2013194484 A JP2013194484 A JP 2013194484A JP 2014040431 A5 JP2014040431 A5 JP 2014040431A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- residues
- pth
- collagen
- polypeptide fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92243307P | 2007-04-09 | 2007-04-09 | |
| US60/922,433 | 2007-04-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503048A Division JP5520811B2 (ja) | 2007-04-09 | 2008-04-09 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015173678A Division JP5989876B2 (ja) | 2007-04-09 | 2015-09-03 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014040431A JP2014040431A (ja) | 2014-03-06 |
| JP2014040431A5 true JP2014040431A5 (2) | 2014-10-02 |
| JP5821066B2 JP5821066B2 (ja) | 2015-11-24 |
Family
ID=39831527
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503048A Active JP5520811B2 (ja) | 2007-04-09 | 2008-04-09 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2013194484A Active JP5821066B2 (ja) | 2007-04-09 | 2013-09-19 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2015173678A Active JP5989876B2 (ja) | 2007-04-09 | 2015-09-03 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2016157345A Active JP6366653B2 (ja) | 2007-04-09 | 2016-08-10 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503048A Active JP5520811B2 (ja) | 2007-04-09 | 2008-04-09 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015173678A Active JP5989876B2 (ja) | 2007-04-09 | 2015-09-03 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2016157345A Active JP6366653B2 (ja) | 2007-04-09 | 2016-08-10 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US8450273B2 (2) |
| EP (2) | EP2155874B1 (2) |
| JP (4) | JP5520811B2 (2) |
| CA (2) | CA2930681C (2) |
| DK (2) | DK3091075T3 (2) |
| ES (2) | ES2583002T3 (2) |
| WO (1) | WO2008124166A2 (2) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2930681C (en) * | 2007-04-09 | 2019-10-15 | The Board Of Trustees Of The University Of Arkansas | Fusion protein of collagen-binding domain and parathyroid hormone |
| ES2531402T3 (es) * | 2008-11-19 | 2015-03-13 | Meiji Seika Pharma Co Ltd | Colagenasa de fusión a la que se une una marca de afinidad, y método para producir la misma |
| EP2405008A1 (en) * | 2010-07-06 | 2012-01-11 | LanthioPep B.V. | Bacterial surface display of thioether-bridge-containing peptides |
| US9173919B2 (en) | 2011-02-16 | 2015-11-03 | Purdue Research Foundation | Collagen-targeted nanoparticles |
| US9248164B2 (en) * | 2011-05-13 | 2016-02-02 | School Juridical Person Kitasato Institute | Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone |
| US9579273B2 (en) | 2011-12-14 | 2017-02-28 | The Kitasato Institute | Delivery of therapeutic agents by a collagen binding protein |
| WO2013120060A1 (en) | 2012-02-09 | 2013-08-15 | The Board Of Trustees Of The University Of Arkansas | Delivery of therapeutic agents by a collagen binding protein |
| WO2014004719A2 (en) * | 2012-06-26 | 2014-01-03 | Worcester Polytechnic Institute | Matrix scaffold with antimicrobial activity |
| WO2016085280A1 (ko) | 2014-11-28 | 2016-06-02 | 서울대학교산학협력단 | 세포 투과성 스테이플 펩타이드, 이의 제조방법 및 그 용도 |
| US11213613B2 (en) | 2015-06-12 | 2022-01-04 | Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences | Three-dimensional tissue scaffold with stem cell attracting element and use thereof |
| MY208384A (en) | 2016-03-01 | 2025-05-05 | Ascendis Pharma Bone Diseases As | Pth prodrugs |
| KR102627405B1 (ko) | 2016-09-29 | 2024-01-18 | 아센디스 파마 본 디지즈 에이/에스 | 조절 방출 pth 화합물을 위한 투여 용법 |
| HRP20230383T1 (hr) | 2016-09-29 | 2023-07-07 | Ascendis Pharma Bone Diseases A/S | Pth spojevi s malim omjerima maksimalne prema minimalnoj koncentraciji |
| US12453778B2 (en) | 2016-09-29 | 2025-10-28 | Ascendis Pharma Bone Diseases A/S | Incremental dose finding in controlled-release PTH compounds |
| CA3045458A1 (en) * | 2016-11-30 | 2018-06-07 | Purdue Research Foundation | Fracture targeted bone regeneration through parathyroid hormone receptor stimulation |
| WO2018148573A1 (en) * | 2017-02-10 | 2018-08-16 | The Board Of Trustees Of The University Of Arkansas | Collagen-binding agent compositions and methods of using the same |
| GB201706781D0 (en) | 2017-04-28 | 2017-06-14 | Univ Sheffield | Parathyroid hormone fusion polypeptide |
| CN107213517B (zh) * | 2017-05-17 | 2020-03-27 | 宁波大学 | 一种复合骨水泥及其制备方法 |
| US20200289621A1 (en) * | 2017-09-22 | 2020-09-17 | Asahi Kasei Pharma Corporation | Teriparatide-containing liquid pharmaceutical composition having excellent stability |
| KR101964376B1 (ko) * | 2017-09-29 | 2019-04-01 | 주식회사 나이벡 | 부갑상선호르몬(parathyroid hormone, PTH)에 골조직 선택성 펩타이드가 결합되어 있는 융합 펩타이드를 포함하는 약학 조성물 및 생체재료 |
| WO2019232283A1 (en) | 2018-05-30 | 2019-12-05 | Purdue Research Foundation | Targeting anabolic drugs for accelerated fracture repair |
| MY209748A (en) | 2019-02-11 | 2025-07-31 | Ascendis Pharma Bone Diseases As | Liquid pharmaceutical formulations of pth conjugates |
| EP4010008A4 (en) * | 2019-08-09 | 2023-08-16 | Phasebio Pharmaceuticals, Inc. | ELP FUSION PROTEINS INCLUDING PARATHYROID HORMONE FOR CONTROLLED AND SUSTAINED RELEASE |
| US12403179B2 (en) | 2021-02-18 | 2025-09-02 | The Board Of Trustees Of The University Of Arkansas | Release of growth factors at wound healing stages |
| KR20250075704A (ko) | 2022-09-30 | 2025-05-28 | 익스텐드 바이오사이언시즈, 인크. | 장기-지속형 부갑상선 호르몬 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8516421D0 (en) | 1985-06-28 | 1985-07-31 | Biotechnology Interface Ltd | Fibronectins |
| DE69429337T3 (de) | 1993-04-02 | 2012-08-30 | Anticancer Inc. | Verfahren zur verabreichung von förderlichen zusammensetzungen auf die haarfollikel |
| US5925552A (en) | 1996-04-25 | 1999-07-20 | Medtronic, Inc. | Method for attachment of biomolecules to medical devices surfaces |
| JP4142743B2 (ja) * | 1996-07-31 | 2008-09-03 | ザ・ジェネラル・ホスピタル・コーポレイション | 副甲状腺ホルモンに関連する新規ペプチド類似体 |
| US6428579B1 (en) | 1998-07-01 | 2002-08-06 | Brown University Research Foundation | Implantable prosthetic devices coated with bioactive molecules |
| US6387663B1 (en) | 1998-07-31 | 2002-05-14 | University Of Southern California | Targeting pharmaceutical agents to injured tissues |
| US7601685B2 (en) | 1998-08-27 | 2009-10-13 | Eidgenossische Technische Hochschule Zurich | Growth factor modified protein matrices for tissue engineering |
| EP1151116A1 (en) | 1999-02-19 | 2001-11-07 | Terumo Kabushiki Kaisha | Collagen-binding physiologically active polypeptide |
| JP2001190280A (ja) * | 1999-02-19 | 2001-07-17 | Terumo Corp | コラーゲン結合性生理活性ポリペプチド |
| US20020102709A1 (en) * | 1999-02-19 | 2002-08-01 | Tetsuya Ishikawa | Collagen-binding physiologically active polypeptide |
| US6908994B1 (en) | 1999-05-10 | 2005-06-21 | The Texas A&M University System | Collagen-binding proteins from enterococcal bacteria |
| US20050124537A1 (en) | 2000-04-27 | 2005-06-09 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| US20040053368A1 (en) | 2000-08-15 | 2004-03-18 | Tetsuya Ishikawa | Collagen-binding hybrid polypeptide |
| JP2002058485A (ja) | 2000-08-16 | 2002-02-26 | Terumo Corp | コラーゲン結合性を有する骨形成促進融合蛋白質 |
| US20020063621A1 (en) | 2000-09-01 | 2002-05-30 | Next Planet, Inc. | Method and apparatus for device communications |
| US6812217B2 (en) | 2000-12-04 | 2004-11-02 | Medtronic, Inc. | Medical device and methods of use |
| JP4560291B2 (ja) | 2001-12-18 | 2010-10-13 | イジュノシッヒ テクニッヒ ホッフシューラ チューリッヒ | 組織操作のための成長因子改変タンパク質マトリクス |
| AU2003256839B2 (en) * | 2002-07-25 | 2009-10-29 | The General Hospital Corporation | Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion |
| US7060299B2 (en) | 2002-12-31 | 2006-06-13 | Battelle Memorial Institute | Biodegradable microparticles that stabilize and control the release of proteins |
| EP1592463B1 (en) | 2003-02-13 | 2006-08-16 | SYNTHES AG Chur | Injectable bone-replacement mixture |
| US20040220094A1 (en) | 2003-05-01 | 2004-11-04 | Skinner Keith K. | Inverse agonist and agonist peptides that stimulate/inhibit hair growth |
| CA2542834C (en) | 2003-10-21 | 2012-04-24 | Igf Oncology, Llc | Conjugates or co-administration of igf-1 receptor ligands with anti-cancer chemotherapeutic agents |
| WO2005046798A1 (en) * | 2003-11-12 | 2005-05-26 | Nps Allelix Corp. | Treatment of bone loss utilizing full length parathyroid hormone |
| EP1557176A1 (en) | 2004-01-26 | 2005-07-27 | Ferring B.V. | Treatment of bone metastases by means of PTH receptor agonists |
| WO2005082941A1 (en) | 2004-02-27 | 2005-09-09 | The University Of Western Ontario | Bone sialoprotein collagen-binding peptides |
| CA2559228C (en) | 2004-04-21 | 2016-06-21 | Enobia Pharma Inc. | Bone delivery conjugates and method of using same to target proteins to bone |
| WO2006047214A2 (en) | 2004-10-21 | 2006-05-04 | Igf Oncology, Llc | Toxins and radionuclides coupled to igf-1 receptor ligands for treatment of cancer |
| WO2006073711A2 (en) | 2005-01-06 | 2006-07-13 | Kuros Biosurgery Ag | Use of a matrix comprising a contrast agent in soft tissues |
| WO2007073661A1 (fr) | 2005-12-26 | 2007-07-05 | Yantai Zhenghai Bio-Technology Co., Ltd. | Matieres de squelette de collagene activees et leurs facteurs speciaux de restauration active fusionnee |
| CA2930681C (en) * | 2007-04-09 | 2019-10-15 | The Board Of Trustees Of The University Of Arkansas | Fusion protein of collagen-binding domain and parathyroid hormone |
| JP2010172247A (ja) | 2009-01-29 | 2010-08-12 | Kitasato Institute | 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織 |
| JPWO2011142425A1 (ja) | 2010-05-12 | 2013-07-22 | 国立大学法人 香川大学 | 上皮層含有組織の再生材および再生評価方法 |
| US9248164B2 (en) | 2011-05-13 | 2016-02-02 | School Juridical Person Kitasato Institute | Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone |
| WO2013120060A1 (en) | 2012-02-09 | 2013-08-15 | The Board Of Trustees Of The University Of Arkansas | Delivery of therapeutic agents by a collagen binding protein |
| US9579273B2 (en) | 2011-12-14 | 2017-02-28 | The Kitasato Institute | Delivery of therapeutic agents by a collagen binding protein |
-
2008
- 2008-04-09 CA CA2930681A patent/CA2930681C/en active Active
- 2008-04-09 EP EP08742686.2A patent/EP2155874B1/en active Active
- 2008-04-09 CA CA2683862A patent/CA2683862C/en active Active
- 2008-04-09 JP JP2010503048A patent/JP5520811B2/ja active Active
- 2008-04-09 US US12/594,547 patent/US8450273B2/en active Active
- 2008-04-09 DK DK16169069.8T patent/DK3091075T3/en active
- 2008-04-09 ES ES08742686.2T patent/ES2583002T3/es active Active
- 2008-04-09 WO PCT/US2008/004589 patent/WO2008124166A2/en not_active Ceased
- 2008-04-09 EP EP16169069.8A patent/EP3091075B1/en active Active
- 2008-04-09 DK DK08742686.2T patent/DK2155874T3/en active
- 2008-04-09 ES ES16169069.8T patent/ES2675174T3/es active Active
-
2013
- 2013-05-20 US US13/898,058 patent/US9062300B2/en active Active
- 2013-09-19 JP JP2013194484A patent/JP5821066B2/ja active Active
-
2015
- 2015-06-18 US US14/743,629 patent/US9528099B2/en active Active
- 2015-09-03 JP JP2015173678A patent/JP5989876B2/ja active Active
-
2016
- 2016-08-10 JP JP2016157345A patent/JP6366653B2/ja active Active
- 2016-12-22 US US15/387,817 patent/US10202434B2/en active Active
-
2019
- 2019-01-16 US US16/249,540 patent/US10358471B2/en active Active
- 2019-07-22 US US16/517,988 patent/US10519213B2/en active Active
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