|
EP2802576B1
(en)
|
2012-01-13 |
2018-06-27 |
Bristol-Myers Squibb Company |
Heterocyclic-substituted pyridyl compounds useful as kinase inhibitors
|
|
ES2575604T3
(es)
*
|
2012-01-13 |
2016-06-29 |
Bristol-Myers Squibb Company |
Compuestos de piridilo sustituidos con tiazolilo o tiadiazolilo útiles como inhibidores cinasa
|
|
WO2014058685A1
(en)
|
2012-10-08 |
2014-04-17 |
Merck Sharp & Dohme Corp. |
Inhibitors of irak4 activity
|
|
JP6215338B2
(ja)
|
2012-11-08 |
2017-10-18 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
キナーゼモジュレーターとして有用な二環式ヘテロ環置換ピリジル化合物
|
|
BR112015009850A2
(pt)
|
2012-11-08 |
2017-07-11 |
Bristol Myers Squibb Co |
compostos de piridila substituídos por heteroarila úteis como moduladores de quinase
|
|
GB201311888D0
(en)
|
2013-07-03 |
2013-08-14 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
GB201311891D0
(en)
|
2013-07-03 |
2013-08-14 |
Glaxosmithkline Ip Dev Ltd |
Novel compound
|
|
TWI667233B
(zh)
|
2013-12-19 |
2019-08-01 |
德商拜耳製藥公司 |
新穎吲唑羧醯胺,其製備方法、含彼等之醫藥製劑及其製造醫藥之用途
|
|
UY35935A
(es)
|
2014-01-03 |
2015-06-30 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
Compuestos de nicotinamida sustituida con heteroarilo como inhibidores de quinasa y moduladores de irak-4
|
|
US20180228907A1
(en)
|
2014-04-14 |
2018-08-16 |
Arvinas, Inc. |
Cereblon ligands and bifunctional compounds comprising the same
|
|
HUE050317T2
(hu)
|
2015-05-20 |
2020-11-30 |
Amgen Inc |
APJ receptor triazol agonistái
|
|
EP3313840B1
(en)
|
2015-06-24 |
2019-07-24 |
Bristol-Myers Squibb Company |
Heteroaryl substituted aminopyridine compounds
|
|
US10618903B2
(en)
|
2015-06-24 |
2020-04-14 |
Bristol-Myers Squibb Company |
Heteroaryl substituted aminopyridine compounds
|
|
ES2822956T3
(es)
*
|
2015-06-24 |
2021-05-05 |
Bristol Myers Squibb Co |
Compuestos de aminopiridina sustituidos con heteroarilo
|
|
US9988369B2
(en)
|
2016-05-03 |
2018-06-05 |
Amgen Inc. |
Heterocyclic triazole compounds as agonists of the APJ receptor
|
|
CN106222183B
(zh)
*
|
2016-07-25 |
2019-11-08 |
南通大学 |
靶向人irak1基因的小干扰rna及其应用
|
|
US10323036B2
(en)
*
|
2016-10-14 |
2019-06-18 |
Nimbus Lakshmi, Inc. |
TYK2 inhibitors and uses thereof
|
|
US10736883B2
(en)
|
2016-11-16 |
2020-08-11 |
Amgen Inc. |
Triazole furan compounds as agonists of the APJ receptor
|
|
EP3541803B1
(en)
|
2016-11-16 |
2020-12-23 |
Amgen Inc. |
Triazole pyridyl compounds as agonists of the apj receptor
|
|
US11046680B1
(en)
|
2016-11-16 |
2021-06-29 |
Amgen Inc. |
Heteroaryl-substituted triazoles as APJ receptor agonists
|
|
WO2018093576A1
(en)
|
2016-11-16 |
2018-05-24 |
Amgen Inc. |
Alkyl substituted triazole compounds as agonists of the apj receptor
|
|
WO2018093579A1
(en)
|
2016-11-16 |
2018-05-24 |
Amgen Inc. |
Triazole phenyl compounds as agonists of the apj receptor
|
|
WO2018093577A1
(en)
|
2016-11-16 |
2018-05-24 |
Amgen Inc. |
Cycloalkyl substituted triazole compounds as agonists of the apj receptor
|
|
TW202340194A
(zh)
|
2017-02-16 |
2023-10-16 |
美商基利科學股份有限公司 |
吡咯并[1,2-b]嗒𠯤衍生物
|
|
PT3621960T
(pt)
|
2017-05-11 |
2021-09-16 |
Bristol Myers Squibb Co |
Tienopiridinas e benzotiofenos úteis como inibidores de irak4
|
|
US11358948B2
(en)
|
2017-09-22 |
2022-06-14 |
Kymera Therapeutics, Inc. |
CRBN ligands and uses thereof
|
|
WO2019060742A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc |
AGENTS FOR DEGRADING PROTEINS AND USES THEREOF
|
|
MA50509A
(fr)
|
2017-11-03 |
2021-06-02 |
Amgen Inc |
Agonistes de triazole fusionnés du récepteur apj
|
|
EP3710443A1
(en)
|
2017-11-17 |
2020-09-23 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 4 polypeptides
|
|
WO2019111218A1
(en)
|
2017-12-08 |
2019-06-13 |
Cadila Healthcare Limited |
Novel heterocyclic compounds as irak4 inhibitors
|
|
WO2019126731A1
(en)
|
2017-12-22 |
2019-06-27 |
Petra Pharma Corporation |
Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
WO2019140380A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
CN110317190A
(zh)
*
|
2018-03-28 |
2019-10-11 |
首都医科大学 |
一种三唑-羧酸酯类衍生物在医药领域的应用
|
|
US11807624B2
(en)
|
2018-05-01 |
2023-11-07 |
Amgen Inc. |
Substituted pyrimidinones as agonists of the APJ receptor
|
|
WO2020010227A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
WO2020010177A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Tricyclic crbn ligands and uses thereof
|
|
TWI842978B
(zh)
*
|
2018-07-13 |
2024-05-21 |
美商基利科學股份有限公司 |
衍生物
|
|
CA3119773A1
(en)
|
2018-11-30 |
2020-06-04 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
TW202112767A
(zh)
|
2019-06-17 |
2021-04-01 |
美商佩特拉製藥公司 |
作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物
|
|
PH12022500002A1
(en)
|
2019-06-28 |
2023-04-03 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
WO2021011868A1
(en)
|
2019-07-17 |
2021-01-21 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
EP3999508B1
(en)
|
2019-07-18 |
2023-08-30 |
Bristol-Myers Squibb Company |
Tricyclic heteroaryl compounds useful as irak4 inhibitors
|
|
WO2021011727A1
(en)
|
2019-07-18 |
2021-01-21 |
Bristol-Myers Squibb Company |
PYRAZOLO[3,4-d]PYRROLO[1,2-b]PYRIDAZINYL COMPOUNDS USEFUL AS IRAK4 INHIBITORS
|
|
US12304916B2
(en)
|
2019-07-23 |
2025-05-20 |
Bristol-Myers Squibb Company |
Thienopyridinyl and thiazolopyridinyl compounds useful as IRAK4 inhibitors
|
|
WO2021026181A1
(en)
|
2019-08-06 |
2021-02-11 |
Bristol-Myers Squibb Company |
Bicyclic heterocyclic compounds useful as irak4 inhibitors
|
|
ES3059914T3
(en)
|
2019-08-13 |
2026-03-24 |
Bristol Myers Squibb Co |
Bicyclic heteroaryl compounds useful as irak4 inhibitors
|
|
WO2021119159A1
(en)
|
2019-12-10 |
2021-06-17 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
KR20220145325A
(ko)
|
2019-12-17 |
2022-10-28 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Irak 분해제 및 이의 용도
|
|
EP4076524A4
(en)
|
2019-12-17 |
2023-11-29 |
Kymera Therapeutics, Inc. |
IRAQ DEGRADERS AND USES THEREOF
|
|
WO2021158495A1
(en)
|
2020-02-03 |
2021-08-12 |
Bristol-Myers Squibb Company |
Benzo[5,6][1,4]dioxino[2,3-b]pyridine compounds useful as irak4 inhibitors
|
|
US12421230B2
(en)
|
2020-02-03 |
2025-09-23 |
Bristol-Myers Squibb Company |
Tricyclic heteroaryl compounds useful as IRAK4 inhibitors
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
MX2023003698A
(es)
*
|
2020-09-30 |
2023-06-15 |
Asahi Kasei Pharma Corp |
Compuesto biciclico que contiene nitrogeno y pirimidina.
|
|
CN116867758A
(zh)
|
2020-12-30 |
2023-10-10 |
凯麦拉医疗公司 |
Irak降解剂和其用途
|
|
US12171768B2
(en)
|
2021-02-15 |
2024-12-24 |
Kymera Therapeutics, Inc. |
IRAK4 degraders and uses thereof
|
|
KR20240020735A
(ko)
|
2021-05-07 |
2024-02-15 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Cdk2 분해제 및 그 용도
|
|
CA3236265A1
(en)
|
2021-10-29 |
2023-05-04 |
William Leong |
Irak4 degraders and synthesis thereof
|
|
CA3243560A1
(en)
|
2022-01-31 |
2023-08-03 |
Kymera Therapeutics, Inc. |
Iraqi Degradation Agents and Their Uses
|
|
WO2026005537A1
(ko)
*
|
2024-06-28 |
2026-01-02 |
주식회사 대웅제약 |
신규한 화합물, 및 이를 포함하는 암 또는 자가 면역 질환의 예방 또는 치료용 약학적 조성물
|