JP2017502016A5 - - Google Patents

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Publication number
JP2017502016A5
JP2017502016A5 JP2016540574A JP2016540574A JP2017502016A5 JP 2017502016 A5 JP2017502016 A5 JP 2017502016A5 JP 2016540574 A JP2016540574 A JP 2016540574A JP 2016540574 A JP2016540574 A JP 2016540574A JP 2017502016 A5 JP2017502016 A5 JP 2017502016A5
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JP
Japan
Prior art keywords
inhibitor
cas number
delta
cancer
intellikine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016540574A
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English (en)
Japanese (ja)
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JP2017502016A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/071744 external-priority patent/WO2015095838A2/en
Publication of JP2017502016A publication Critical patent/JP2017502016A/ja
Publication of JP2017502016A5 publication Critical patent/JP2017502016A5/ja
Pending legal-status Critical Current

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JP2016540574A 2013-12-20 2014-12-19 1型mek阻害剤およびerk阻害剤の組み合わせを使用するがんの処置 Pending JP2017502016A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361919606P 2013-12-20 2013-12-20
US61/919,606 2013-12-20
PCT/US2014/071744 WO2015095838A2 (en) 2013-12-20 2014-12-19 Cancer treatments using combinations of mek type i and erk inhibitors

Publications (2)

Publication Number Publication Date
JP2017502016A JP2017502016A (ja) 2017-01-19
JP2017502016A5 true JP2017502016A5 (2) 2018-02-01

Family

ID=53403902

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016540574A Pending JP2017502016A (ja) 2013-12-20 2014-12-19 1型mek阻害剤およびerk阻害剤の組み合わせを使用するがんの処置

Country Status (5)

Country Link
US (1) US20160310477A1 (2)
EP (1) EP3082422A4 (2)
JP (1) JP2017502016A (2)
AU (1) AU2014368925A1 (2)
WO (1) WO2015095838A2 (2)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010007419A (es) 2008-01-04 2010-11-12 Intellikine Inc Ciertas entidades quimicas, composiciones y metodos.
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
ES2637113T3 (es) 2011-01-10 2017-10-10 Infinity Pharmaceuticals, Inc. Procedimientos para preparar isoquinolinonas y formas sólidas de isoquinolinonas
US8828998B2 (en) 2012-06-25 2014-09-09 Infinity Pharmaceuticals, Inc. Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
AU2013337717B2 (en) 2012-11-01 2018-10-25 Infinity Pharmaceuticals, Inc. Treatment of cancers using PI3 kinase isoform modulators
WO2015160975A2 (en) 2014-04-16 2015-10-22 Infinity Pharmaceuticals, Inc. Combination therapies
JP6886165B2 (ja) * 2016-02-15 2021-06-16 国立大学法人山形大学 ガン抑制薬及び抗腫瘍剤、腫瘍再発防止剤、腫瘍発生予防剤
SG11201811237WA (en) 2016-06-24 2019-01-30 Infinity Pharmaceuticals Inc Combination therapies
EP3624896A4 (en) * 2017-05-16 2021-03-31 Biomed Valley Discoveries, Inc. COMPOSITIONS AND METHODS OF TREATMENT OF CANCER WITH ATYPICAL BRAF MUTATIONS
CN112402413B (zh) * 2020-11-26 2022-03-08 重庆三峡医药高等专科学校 野马追倍半萜内酯b在制备抗肝癌药物中的应用及一种抗肝癌药物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1110957A1 (en) * 1999-12-24 2001-06-27 Applied Research Systems ARS Holding N.V. Benzazole derivatives and their use as JNK modulators
WO2004004644A2 (en) * 2002-07-05 2004-01-15 Beth Israel Deaconess Medical Center Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms
UA84930C2 (ru) * 2004-05-14 2008-12-10 Вертекс Фармасьютикалс Инкорпорейтед Пиррольные соединения как ингибиторы протеинкиназ erk, их синтез и соответствующие промежуточные соединения
JP2008514635A (ja) * 2004-09-27 2008-05-08 コーザン バイオサイエンシス インコーポレイテッド 特異的キナーゼ阻害剤
WO2008067069A2 (en) * 2006-10-19 2008-06-05 Oregon Health & Science University Mitogen activated protein kinase phosphatase 4 (mkp4) and methods of use thereof
MY148609A (en) * 2007-06-05 2013-05-15 Merck Sharp & Dohme Polycyclic indazole derivatives and their use as erk inhibitors for the treatment of cancer
ME01526B (me) * 2009-02-26 2014-04-20 Boehringer Ingelheim Int Jedinjenja kao b1 antagonisti bradikinina
AU2010299835A1 (en) * 2009-09-28 2012-04-05 Centre National De La Recherche Scientifique Irreversible inhibitors useful for the treatment of kinase-related pathologies
MY170236A (en) * 2010-10-06 2019-07-11 Glaxosmithkline Llc Benzimidazole derivatives as pi3 kinase inhibitors

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