JP2017523796A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017523796A5 JP2017523796A5 JP2017506955A JP2017506955A JP2017523796A5 JP 2017523796 A5 JP2017523796 A5 JP 2017523796A5 JP 2017506955 A JP2017506955 A JP 2017506955A JP 2017506955 A JP2017506955 A JP 2017506955A JP 2017523796 A5 JP2017523796 A5 JP 2017523796A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- following sequence
- encephalitis virus
- structural protein
- equine encephalitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000710959 Venezuelan equine encephalitis virus Species 0.000 description 1
- 108010087302 Viral Structural Proteins Proteins 0.000 description 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462035037P | 2014-08-08 | 2014-08-08 | |
| US62/035,037 | 2014-08-08 | ||
| US201462079128P | 2014-11-13 | 2014-11-13 | |
| US62/079,128 | 2014-11-13 | ||
| US201562101514P | 2015-01-09 | 2015-01-09 | |
| US62/101,514 | 2015-01-09 | ||
| US201562120569P | 2015-02-25 | 2015-02-25 | |
| US62/120,569 | 2015-02-25 | ||
| US201562198949P | 2015-07-30 | 2015-07-30 | |
| US62/198,949 | 2015-07-30 | ||
| PCT/JP2015/003997 WO2016021209A1 (en) | 2014-08-08 | 2015-08-07 | Virus like particle comprising modified envelope protein e3 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017523796A JP2017523796A (ja) | 2017-08-24 |
| JP2017523796A5 true JP2017523796A5 (2) | 2018-09-06 |
| JP6824154B2 JP6824154B2 (ja) | 2021-02-03 |
Family
ID=55263499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017506955A Active JP6824154B2 (ja) | 2014-08-08 | 2015-08-07 | 修飾エンベロープタンパク質e3を含むウイルス様粒子 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9969986B2 (2) |
| EP (1) | EP3177720B1 (2) |
| JP (1) | JP6824154B2 (2) |
| CN (1) | CN106795513B (2) |
| TW (1) | TWI720946B (2) |
| WO (1) | WO2016021209A1 (2) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102181258B1 (ko) | 2012-02-16 | 2020-11-20 | 브이엘피 테라퓨틱스 엘엘씨 | 바이러스 유사 입자 조성물 |
| SG10201709917VA (en) | 2013-06-03 | 2017-12-28 | Vlp Therapeutics Llc | Malaria vaccine |
| TWI676636B (zh) | 2013-07-12 | 2019-11-11 | Vlp醫療股份有限公司 | 包含pd-1抗原或pd-1配體抗原的類病毒粒子 |
| WO2015054639A1 (en) | 2013-10-11 | 2015-04-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Epstein-barr virus vaccines |
| US10385101B2 (en) | 2014-08-08 | 2019-08-20 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
| US9969986B2 (en) | 2014-08-08 | 2018-05-15 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
| KR102532832B1 (ko) | 2014-09-11 | 2023-05-16 | 브이엘피 테라퓨틱스 인코포레이티드 | 플라비바이러스 바이러스 유사 입자 |
| US11191727B2 (en) | 2014-12-31 | 2021-12-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Multivalent nanoparticle-based vaccines |
| US10166281B2 (en) | 2015-09-04 | 2019-01-01 | Vlp Therapeutics, Llc | Method and composition for modulating immune response |
| WO2017150683A1 (en) * | 2016-03-04 | 2017-09-08 | Vlp Therapeutics, Llc | Zika virus virus like particle |
| WO2017221076A1 (en) * | 2016-06-24 | 2017-12-28 | Institut Pasteur | Compositions and methods comprising measles virus defective interfering particles for the prevention of infectious diseases |
| SG10201912944QA (en) | 2016-09-02 | 2020-02-27 | The Usa As Represented By The Secretary | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
| US11129886B2 (en) | 2017-03-28 | 2021-09-28 | Children's Hospital Medical Center | VLP-based bivalent Ebola vaccines and methods of making and using same |
| ES2963635T3 (es) * | 2017-03-28 | 2024-04-01 | Ohio State Innovation Foundation | Vacunas de péptido PD1 humano y usos de las mismas |
| SG11202005792RA (en) * | 2017-12-20 | 2020-07-29 | Vlp Therapeutics Llc | Alphavirus replicon particle |
| WO2019153042A1 (en) * | 2018-02-07 | 2019-08-15 | Imugene Limited | A vaccine composition and uses thereof |
| WO2019156223A1 (ja) * | 2018-02-09 | 2019-08-15 | 国立大学法人大阪大学 | チクングニアウイルスに対する抗体またはその抗原結合断片、およびその用途 |
| FR3078536A1 (fr) * | 2018-03-05 | 2019-09-06 | Peptinov Sas | Composition vaccinale anti-pd-1 |
| FR3078535B1 (fr) * | 2018-03-05 | 2024-02-09 | Peptinov Sas | Composition vaccinale anti-pd-l1 |
| CN109536464B (zh) * | 2018-12-10 | 2022-06-10 | 中国科学院武汉病毒研究所 | 一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用 |
| TWI891771B (zh) | 2020-04-17 | 2025-08-01 | 美商Vlp醫療股份有限公司 | 冠狀病毒疫苗 |
| AU2021264216A1 (en) | 2020-04-30 | 2022-11-10 | Vlp Therapeutics, Inc. | Cytokine immunotherapy |
| EP4326858A4 (en) * | 2021-04-23 | 2025-03-12 | VLP Therapeutics, Inc. | GALECTIN-TARGETED IMMUNOTHERAPY |
| CN115466330B (zh) * | 2021-06-10 | 2023-10-20 | 清华大学 | 一种基于病毒样颗粒呈递冠状病毒受体结合区的冠状病毒亚单位疫苗 |
| EP4377449A1 (en) * | 2021-07-26 | 2024-06-05 | Beam Therapeutics, Inc. | Pseudotyped recombinant lyssaviruses for gene therapy |
| CN119546752A (zh) * | 2022-04-18 | 2025-02-28 | Cyn-K 生物公司 | 炎性病况的治疗 |
| CN116042657A (zh) * | 2023-01-16 | 2023-05-02 | 上海复诺健生物科技有限公司 | 自复制信使核糖核酸疫苗 |
| WO2025084276A1 (ja) * | 2023-10-16 | 2025-04-24 | Cyn-Kバイオ株式会社 | 肥満の処置 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8923123D0 (en) | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| AU2927892A (en) | 1991-11-16 | 1993-06-15 | Smithkline Beecham Biologicals (Sa) | Hybrid protein between cs from plasmodium and hbsag |
| US5580773A (en) | 1992-06-17 | 1996-12-03 | Korea Green Cross Corporation | Chimeric immunogenic gag-V3 virus-like particles of the human immunodeficiency virus (HIV) |
| JPH07291996A (ja) | 1994-03-01 | 1995-11-07 | Yuu Honshiyo | ヒトにおけるプログラムされた細胞死に関連したポリペプチド、それをコードするdna、そのdnaからなるベクター、そのベクターで形質転換された宿主細胞、そのポリペプチドの抗体、およびそのポリペプチドまたはその抗体を含有する薬学的組成物 |
| WO1997012048A1 (en) | 1995-09-27 | 1997-04-03 | Medical Research Council | Recombinant viruses incorporating a protease cleavable protein |
| EP1054973A1 (en) | 1998-02-11 | 2000-11-29 | Maxygen, Inc. | Antigen library immunization |
| PL354286A1 (en) | 1999-08-23 | 2003-12-29 | Dana-Farber Cancer Institutedana-Farber Cancer Institute | Pd-1, a receptor for b7-4, and uses therefor |
| AU2002344190B2 (en) | 2001-05-30 | 2007-10-18 | Transgene S.A. | Adenovirus protein IX, Its domains involved in capsid assembly, transcriptional activity and nuclear reorganization |
| AU2003281200A1 (en) | 2002-07-03 | 2004-01-23 | Tasuku Honjo | Immunopotentiating compositions |
| AU2003295470A1 (en) | 2002-11-13 | 2004-06-03 | The United States Of America As Represented By The Secretary Of The Navy | Methods and compositions for inducing immune responses and protective immunity by priming with alphavirus replicon vaccines |
| CA2527636A1 (en) * | 2003-05-29 | 2005-01-06 | United States Army Medical Research Institute For Infectious Diseases, A Research Laboratory Owned And Operated By The United States Government A | Live attenuated viral vaccines for eastern equine encephalitis virus |
| CA2547511A1 (en) | 2003-12-01 | 2005-07-28 | Dow Global Technolgies Inc. | Recombinant icosahedral virus like particle production in pseudomonads |
| EA016648B1 (ru) | 2004-10-14 | 2012-06-29 | Круселл Холланд Б.В. | Применение дефектного по репликации рекомбинантного аденовируса, содержащего гетерологичную нуклеиновую кислоту, кодирующую антиген cs возбудителя малярии, и белкового антигена, содержащего белок cs или его фрагмент, для лечения или профилактики малярии |
| WO2006088229A1 (ja) | 2005-02-16 | 2006-08-24 | The Circle For The Promotion Of Science And Engineering | 改変されたウイルスカプシドタンパク質及びその使用 |
| CA2611861C (en) | 2005-06-08 | 2017-11-28 | The Brigham And Women's Hospital, Inc. | Methods and compositions for the treatment of persistent infections |
| GB0513421D0 (en) | 2005-06-30 | 2005-08-03 | Glaxosmithkline Biolog Sa | Vaccines |
| CU23586A1 (es) | 2005-11-22 | 2010-10-30 | Ct Ingenieria Genetica Biotech | Métodos y proteínas para el tratamiento profiláctico y/o terapéutico de los cuatro serotipos del virus de dengue y otros flavivirus |
| US8216996B2 (en) | 2006-03-03 | 2012-07-10 | Ono Pharmaceutical Co., Ltd. | Multimer of extracellular domain of cell surface functional molecule |
| US20100120092A1 (en) | 2006-08-30 | 2010-05-13 | Hepgenics Pty Ltd. | Recombinant proteins and virus like particles comprising l and s polypeptides of avian hepadnaviridae and methods, nucleic acid constructs, vectors and host cells for producing same |
| AU2008338803B2 (en) | 2007-11-26 | 2015-02-05 | Glaxosmithkline Biologicals S.A. | Methods of generating alphavirus particles |
| EP2370455B1 (en) * | 2008-11-26 | 2019-07-03 | Government of the United States of America, as represented by the Secretary, Department of Health and Human Services | Virus like particle compositions and methods of use |
| PL2370099T3 (pl) * | 2008-12-09 | 2016-10-31 | Zmodyfikowane białka F RSV i sposoby ich zastosowania | |
| EP2477650B8 (en) | 2009-09-18 | 2019-10-09 | FRAUNHOFER USA Inc. | Virus like particles comprising target proteins fused to plant viral coat proteins |
| WO2012006180A1 (en) | 2010-06-29 | 2012-01-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hiv immunogens |
| WO2012023995A1 (en) | 2010-08-18 | 2012-02-23 | Takayuki Shiratsuchi | Modification of recombinant adenovirus capsid protein with immunogenic plasmodium circumsporozoite protein epitopes |
| US9487563B2 (en) | 2011-01-31 | 2016-11-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Virus-like particles and methods of use |
| CN103561771B (zh) | 2011-03-17 | 2019-01-04 | 伯明翰大学 | 重新定向的免疫治疗 |
| EP2720715B1 (en) | 2011-06-17 | 2017-08-09 | Bharat Biotech International Limited | Vaccine composition comprising an inactivated chikungunya virus strain |
| CN102321639B (zh) | 2011-09-08 | 2013-06-26 | 中国疾病预防控制中心病毒病预防控制所 | 基孔肯雅病毒病毒样颗粒的制备方法和应用 |
| SG11201401733VA (en) | 2011-10-25 | 2014-09-26 | Florida Gulf Coast University | Vaccines and methods for creating a vaccine for inducing immunity to all dengue virus serotypes |
| KR102181258B1 (ko) * | 2012-02-16 | 2020-11-20 | 브이엘피 테라퓨틱스 엘엘씨 | 바이러스 유사 입자 조성물 |
| US9821050B2 (en) | 2012-04-02 | 2017-11-21 | The University Of North Carolina At Chapel Hill | Chimeric dengue virus E glycoproteins comprising mutant domain I and domain II hinge regions |
| HRP20181102T1 (hr) | 2012-05-16 | 2018-09-07 | Immune Design Corp | Cjepiva za hsv-2 |
| SG10201709917VA (en) | 2013-06-03 | 2017-12-28 | Vlp Therapeutics Llc | Malaria vaccine |
| TWI676636B (zh) | 2013-07-12 | 2019-11-11 | Vlp醫療股份有限公司 | 包含pd-1抗原或pd-1配體抗原的類病毒粒子 |
| US10060924B2 (en) | 2014-03-18 | 2018-08-28 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Distinguishing flavivirus infection using a recombinant mutant envelope protein |
| US9969986B2 (en) | 2014-08-08 | 2018-05-15 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
| US10385101B2 (en) | 2014-08-08 | 2019-08-20 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
| US9363353B1 (en) | 2014-12-04 | 2016-06-07 | Hon Man Ashley Chik | Mobile phone docks with multiple circulating phone connectors |
| US11191727B2 (en) * | 2014-12-31 | 2021-12-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Multivalent nanoparticle-based vaccines |
| JPWO2016199936A1 (ja) | 2015-06-12 | 2018-04-05 | 国立大学法人三重大学 | ヒトパラインフルエンザ2型ウイルスベクター及びワクチン |
| US10799575B2 (en) | 2015-06-25 | 2020-10-13 | Technovax, Inc. | Flavivirus and alphavirus virus-like particles (VLPS) |
| EP3322441A4 (en) | 2015-07-16 | 2018-12-19 | Bharat Biotech International Limited | Vaccine compositions |
| MA42502A (fr) | 2015-07-21 | 2018-05-30 | Modernatx Inc | Vaccins contre une maladie infectieuse |
| CN106085974B (zh) | 2016-06-07 | 2019-08-09 | 博奥生物集团有限公司 | 一种寨卡病毒假病毒颗粒及其制备方法 |
-
2015
- 2015-08-07 US US14/820,785 patent/US9969986B2/en active Active
- 2015-08-07 EP EP15829311.8A patent/EP3177720B1/en active Active
- 2015-08-07 TW TW104125774A patent/TWI720946B/zh active
- 2015-08-07 JP JP2017506955A patent/JP6824154B2/ja active Active
- 2015-08-07 WO PCT/JP2015/003997 patent/WO2016021209A1/en not_active Ceased
- 2015-08-07 CN CN201580054670.4A patent/CN106795513B/zh active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017523796A5 (2) | ||
| SG11202003746UA (en) | Novel, highly active pyrazolo-piperidine substituted indole-2-carboxamides active against the hepatitis b virus (hbv) | |
| JP2019194236A5 (2) | ||
| JP2017048194A5 (2) | ||
| JP2018024670A5 (2) | ||
| JP2017514877A5 (2) | ||
| EA201790630A1 (ru) | Способы получения рибозидов | |
| JP2016525888A5 (2) | ||
| EP4659816A3 (en) | MODIFIED CAPSID PROTEINS FOR IMPROVED PARVOVIRUS VECTOR DELIVERY | |
| JP2019524645A5 (2) | ||
| JP2016153424A5 (2) | ||
| JP2017186358A5 (2) | ||
| JP2017008120A5 (2) | ||
| JP2017532302A5 (2) | ||
| JP2011527560A5 (2) | ||
| DK3250591T3 (da) | Humane antistoffer mod ebolavirus-glykoprotein | |
| EA201890527A1 (ru) | Терапевтические вакцины против hpv18 | |
| LT3512863T (lt) | 2'-pakeistieji-n6-pakeistieji purino nukleotidai, skirti gydymui rnr virusu | |
| JP2014028813A5 (2) | ||
| JP2017501211A5 (2) | ||
| EP4043031A3 (en) | Zika viral antigen constructs | |
| JP2018116258A5 (2) | ||
| JP2018030858A5 (2) | ||
| JP2015188307A5 (2) | ||
| HUE052833T2 (hu) | Eljárás 2,5-furándikarbonsav (FDCA) elõállítására |