JP3647048B2 - デング熱ウイルスのプレm/mエピトープ、合成ペプチド、キメラタンパク質およびその用途 - Google Patents

デング熱ウイルスのプレm/mエピトープ、合成ペプチド、キメラタンパク質およびその用途 Download PDF

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JP3647048B2
JP3647048B2 JP53348698A JP53348698A JP3647048B2 JP 3647048 B2 JP3647048 B2 JP 3647048B2 JP 53348698 A JP53348698 A JP 53348698A JP 53348698 A JP53348698 A JP 53348698A JP 3647048 B2 JP3647048 B2 JP 3647048B2
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protein
virus
dengue
seq
peptides
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JP2001508457A (ja
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ラムド,スサーナ バスケス
ティラド,グアダルペ グスマン
ニエト,ヘラルド エンリケ ギジェン
ラソ,オルランド ルイス パルド
サンティアゴ,グライ チネア
ディアス,アナ ベアトリス ペレス
アントゥネス,マリッサ プポ
ロチェ,ロスマリ ロドリゲス
アコスタ,オスバルト レイエス
ペレス,イルダ エリサ ガライ
パロマレス,ガブリエル パドロン
ベラ,マイリン アルバレス
ディアス,ルイス モリエル
インスイタ,オマイダ ペレス
マルティネス デ ラ コテラ,ホセ ルイス ペレグリノ
Original Assignee
セントロ デ インヘニエリア ヘネティカ イ ビオテクノロヒア(セーイーヘーベー)
インスティトゥト デ メディシナ トロピカル“ペドロ コウリ”
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP53348698A 1997-01-15 1998-01-13 デング熱ウイルスのプレm/mエピトープ、合成ペプチド、キメラタンパク質およびその用途 Expired - Fee Related JP3647048B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CU1997013A CU22683A1 (es) 1997-01-15 1997-01-15 Epítopes de la proteína pre-m/m del virus del dengue, péptidos sintéticos, proteínas quiméricas y sus usos
CU13/97 1997-01-15
PCT/CU1998/000001 WO1998031814A1 (es) 1997-01-15 1998-01-13 Epitopes de la proteina pre-m/m del virus del dengue, peptidos sinteticos

Publications (2)

Publication Number Publication Date
JP2001508457A JP2001508457A (ja) 2001-06-26
JP3647048B2 true JP3647048B2 (ja) 2005-05-11

Family

ID=5459193

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53348698A Expired - Fee Related JP3647048B2 (ja) 1997-01-15 1998-01-13 デング熱ウイルスのプレm/mエピトープ、合成ペプチド、キメラタンパク質およびその用途

Country Status (14)

Country Link
US (1) US6383488B1 (de)
EP (1) EP0966535B1 (de)
JP (1) JP3647048B2 (de)
CN (1) CN1198933C (de)
AT (1) ATE284444T1 (de)
AU (1) AU743414B2 (de)
BR (1) BR9807486A (de)
CA (1) CA2277816A1 (de)
CU (1) CU22683A1 (de)
DE (1) DE69828032T2 (de)
ES (1) ES2235310T3 (de)
MY (1) MY120971A (de)
NO (1) NO993468L (de)
WO (1) WO1998031814A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU23245A1 (es) 2001-07-16 2007-10-17 Inst De Medicina Tropical Pedr CADENAS QUIMéRICAS CODIFICANTES PARA PROTEINAS INDUCTORAS DE EFECTOS CONTRA VIRUS. PREPARADOS UTILIZANDO PROTEINAS QUIMéRICAS
AU2002356690B2 (en) * 2001-12-04 2008-07-24 Bavarian Nordic A/S Flavivirus NS1 subunit vaccine
EP1454988A1 (de) * 2003-03-03 2004-09-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Infektiöse Flavivirus Pseudo-Partikel, welche funktionelle prM-E Hüllproteine enthalten
US7281274B2 (en) * 2003-10-16 2007-10-09 Lmp Media Llc Electronic media distribution system
WO2006025990A2 (en) * 2004-07-27 2006-03-09 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Diseases Control And Prevention Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes and methods for their use
CU23578A1 (es) 2005-09-16 2010-09-30 Ct Ingenieria Genetica Biotech Proteína de la cápsida del virus dengue inductora de respuesta protectora y composición vacunal
CU23630A1 (es) 2006-10-30 2011-02-24 Ct Ingenieria Genetica Biotech Moléculas peptídicas quiméricas con propiedades antivirales contra los virus de la familia flaviviridae
WO2009024534A2 (en) * 2007-08-17 2009-02-26 Intercell Ag Japanese encephalitis virus (jev) and tick-borne encephalitis virus (tbev) peptides stimulating human t cell responses
CU20080028A6 (es) 2008-02-29 2011-02-24 Ct Ingenieria Genetica Biotech Compuestos químicos obtenidos in silico para la preparación de composiciones farmacéuticas para atenuar o inhibir la infección por virus dengue y otros flavivirus
CN102272155B (zh) * 2008-10-13 2018-05-25 生物医学研究所 登革热病毒中和抗体及其用途
CN101921310B (zh) * 2009-06-15 2014-03-12 温州医学院 登革病毒特异性hla-a2限制性表位肽及应用
WO2011133112A1 (en) * 2010-04-20 2011-10-27 National University Of Singapore Cell penetrating peptide derived from the premembrane protein of flavivirus
WO2012159187A2 (en) * 2011-05-26 2012-11-29 Universidade Federal Do Rio De Janeiro - Ufrj Denv-derived peptides and methods for the inhibition of the flavivirus replication
CU24188B1 (es) * 2012-12-27 2016-07-29 Ct De Ingeniería Genética Y Biotecnología Composición vacunal contra el virus dengue
KR20160027019A (ko) * 2013-06-26 2016-03-09 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 뎅기 바이러스 백신에 대한 방법 및 조성물
TWI769185B (zh) * 2016-10-27 2022-07-01 海樂源有限公司 登革熱類病毒顆粒、抗登革熱病毒抗體、及含其之組合物
CN116082499B (zh) * 2021-11-08 2023-10-27 东莞市朋志生物科技有限公司 一种抗登革ns1蛋白的抗体及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6093296A (en) * 1995-06-07 1996-12-30 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Infectious dengue 2 virus pdk-53 as quadravalent vaccine

Also Published As

Publication number Publication date
ES2235310T3 (es) 2005-07-01
CN1249781A (zh) 2000-04-05
US6383488B1 (en) 2002-05-07
CN1198933C (zh) 2005-04-27
CA2277816A1 (en) 1998-07-23
NO993468D0 (no) 1999-07-14
WO1998031814A1 (es) 1998-07-23
DE69828032T2 (de) 2005-12-01
AU5649998A (en) 1998-08-07
EP0966535B1 (de) 2004-12-08
DE69828032D1 (de) 2005-01-13
BR9807486A (pt) 2000-03-21
HK1025999A1 (en) 2000-12-01
CU22683A1 (es) 2001-07-20
AU743414B2 (en) 2002-01-24
ATE284444T1 (de) 2004-12-15
MY120971A (en) 2005-12-30
EP0966535A1 (de) 1999-12-29
JP2001508457A (ja) 2001-06-26
NO993468L (no) 1999-09-14

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