JP4380925B2 - ナノパーティクル組成物用の表面安定剤としてのｐｅｇ誘導体化脂質の使用 - Google Patents

ナノパーティクル組成物用の表面安定剤としてのｐｅｇ誘導体化脂質の使用 Download PDF

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Publication number: JP4380925B2
Authority: JP; Japan
Prior art keywords: peg; drug; less; vitamin; lipid
Prior art date: 1999-03-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP2000602040A

Other languages

English (en)

Japanese (ja)

Other versions

JP2002538099A (ja

Inventor

リバーサイジ，エレイン

エー．ゴターディー，グレタ

Original Assignee

エランファーマインターナショナル，リミティド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-03

Filing date

2000-02-14

Publication date

2009-12-09

2000-02-14 Application filed by エランファーマインターナショナル，リミティド filed Critical エランファーマインターナショナル，リミティド

2002-11-12 Publication of JP2002538099A publication Critical patent/JP2002538099A/ja

2009-12-09 Application granted granted Critical

2009-12-09 Publication of JP4380925B2 publication Critical patent/JP4380925B2/ja

2020-02-14 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

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Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP2000602040A 1999-03-03 2000-02-14 ナノパーティクル組成物用の表面安定剤としてのｐｅｇ誘導体化脂質の使用 Expired - Lifetime JP4380925B2 (ja)

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US09/261,151 US6270806B1 (en)	1999-03-03	1999-03-03	Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions
US09/261,151		1999-03-03
PCT/US2000/003676 WO2000051572A1 (en)	1999-03-03	2000-02-14	Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions

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JP2009024191A Division JP2009102420A (ja)	1999-03-03	2009-02-04	ナノパーティクル組成物用の表面安定剤としてのｐｅｇ誘導体化脂質の使用

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JP2002538099A JP2002538099A (ja)	2002-11-12
JP4380925B2 true JP4380925B2 (ja)	2009-12-09

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JP2009024191A Withdrawn JP2009102420A (ja)	1999-03-03	2009-02-04	ナノパーティクル組成物用の表面安定剤としてのｐｅｇ誘導体化脂質の使用

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US (1)	US6270806B1 (de)
EP (1)	EP1156788B1 (de)
JP (2)	JP4380925B2 (de)
AT (1)	ATE230982T1 (de)
AU (1)	AU3489600A (de)
CA (1)	CA2362508C (de)
DE (1)	DE60001219T2 (de)
WO (1)	WO2000051572A1 (de)

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1999
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2000
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- 2000-02-14 WO PCT/US2000/003676 patent/WO2000051572A1/en not_active Ceased
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2009
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Publication number	Publication date
US6270806B1 (en)	2001-08-07
ATE230982T1 (de)	2003-02-15
EP1156788A1 (de)	2001-11-28
DE60001219D1 (de)	2003-02-20
JP2009102420A (ja)	2009-05-14
WO2000051572B1 (en)	2000-11-23
CA2362508A1 (en)	2000-09-08
JP2002538099A (ja)	2002-11-12
WO2000051572A1 (en)	2000-09-08
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