JP4410675B2 - アスタキサンチン中鎖脂肪酸エステル、その製造法、およびそれらを含有する組成物 - Google Patents

アスタキサンチン中鎖脂肪酸エステル、その製造法、およびそれらを含有する組成物 Download PDF

Info

Publication number
JP4410675B2
JP4410675B2 JP2004501368A JP2004501368A JP4410675B2 JP 4410675 B2 JP4410675 B2 JP 4410675B2 JP 2004501368 A JP2004501368 A JP 2004501368A JP 2004501368 A JP2004501368 A JP 2004501368A JP 4410675 B2 JP4410675 B2 JP 4410675B2
Authority
JP
Japan
Prior art keywords
astaxanthin
fatty acid
chain fatty
medium chain
lipase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2004501368A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2003093229A1 (ja
Inventor
元男 角田
正宏 中尾
菜美 冨森
耕士 並川
治一 深見
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Holdings Ltd
Original Assignee
Suntory Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Holdings Ltd filed Critical Suntory Holdings Ltd
Publication of JPWO2003093229A1 publication Critical patent/JPWO2003093229A1/ja
Application granted granted Critical
Publication of JP4410675B2 publication Critical patent/JP4410675B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A61Q1/06—Lipsticks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6454—Glycerides by esterification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
JP2004501368A 2002-04-30 2003-04-28 アスタキサンチン中鎖脂肪酸エステル、その製造法、およびそれらを含有する組成物 Expired - Fee Related JP4410675B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002128989 2002-04-30
JP2002128989 2002-04-30
PCT/JP2003/005443 WO2003093229A1 (en) 2002-04-30 2003-04-28 Astaxanthin medium-chain fatty acid ester, process for producing the same and composition containing the ester

Publications (2)

Publication Number Publication Date
JPWO2003093229A1 JPWO2003093229A1 (ja) 2005-09-08
JP4410675B2 true JP4410675B2 (ja) 2010-02-03

Family

ID=29397288

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004501368A Expired - Fee Related JP4410675B2 (ja) 2002-04-30 2003-04-28 アスタキサンチン中鎖脂肪酸エステル、その製造法、およびそれらを含有する組成物

Country Status (12)

Country Link
US (1) US20050228188A1 (de)
EP (1) EP1500645B1 (de)
JP (1) JP4410675B2 (de)
KR (1) KR100941899B1 (de)
CN (1) CN100374417C (de)
AU (1) AU2003234765B2 (de)
CA (1) CA2481704C (de)
DE (1) DE60328374D1 (de)
IL (1) IL164089A0 (de)
MY (1) MY137041A (de)
SG (1) SG150385A1 (de)
WO (1) WO2003093229A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7145025B2 (en) * 2002-07-29 2006-12-05 Hawaii Biotech, Inc. Structural carotenoid analogs for the inhibition and amelioration of disease
GB0501365D0 (en) * 2005-01-21 2005-03-02 Promar As Compositions
US20070293568A1 (en) 2006-06-16 2007-12-20 Yamaha Hatsudoki Kabushiki Kaisha Neurocyte Protective Agent
EP1952845A1 (de) * 2007-01-26 2008-08-06 DSMIP Assets B.V. Verwendung eines Astaxathinderivats für kosmetische Zwecke
KR20110021886A (ko) * 2008-05-15 2011-03-04 프로노바 바이오파마 노르지 에이에스 크릴 오일 처리 방법
WO2010038964A2 (ko) * 2008-09-30 2010-04-08 주식회사 유맥스 크릴로부터 유용성분 추출분리방법 및 관련 제품
SG11201609405VA (en) 2014-05-20 2016-12-29 Fuji Chem Ind Co Ltd Carotenoid derivative, pharmaceutically acceptable salt thereof, and pharmaceutically acceptable ester or amide thereof
CN104513844A (zh) * 2014-12-17 2015-04-15 北京科技大学 一种利用脂肪酶催化合成虾青素琥珀酸酯的方法
WO2016146803A1 (de) * 2015-03-19 2016-09-22 Basf Se Astaxanthinzusammensetzungen (iii)
EP3270910B1 (de) * 2015-03-19 2019-05-22 Basf Se Astaxanthinzusammensetzungen (iv)
BR112017019831A2 (pt) * 2015-03-19 2018-05-29 Basf Se uso de composições de astaxantina, composição, e, processo para preparação de alimento ou alimento animal
CN105418472B (zh) * 2015-11-21 2017-05-10 中国海洋大学 一种利用溶剂分级结晶分离虾青素单双酯的方法
CN106278979B (zh) * 2016-08-16 2017-12-05 集美大学 一种虾青素棕榈酸‑二十二碳二烯酸双酯的制备方法
WO2018050795A1 (en) 2016-09-16 2018-03-22 Basf Se Process for preparing of carotenoid mono-esters
CN109715605B (zh) * 2016-09-16 2022-04-12 巴斯夫欧洲公司 制备类胡萝卜素单酯的方法
WO2018050793A1 (en) * 2016-09-16 2018-03-22 Basf Se Process for preparing phosphonium salt esters as building blocks for carotenoides
CN109251945B (zh) * 2018-10-16 2021-08-20 云南爱尔康生物技术有限公司 一种制备虾青素中链脂肪酸单酯和虾青素中链脂肪酸双酯的方法
WO2021085916A1 (ko) * 2019-10-29 2021-05-06 주식회사 내추럴바이오트리 에스테르 교환 반응을 통한 아스타잔틴 모노에스테르의 제조방법
KR102423643B1 (ko) * 2019-10-29 2022-07-22 주식회사 내추럴바이오트리 에스테르 교환 반응을 통한 아스타잔틴 모노에스테르의 제조방법
KR102423638B1 (ko) * 2019-10-29 2022-07-22 주식회사 내추럴바이오트리 아스타잔틴 모노에스테르의 제조방법
CN110940743A (zh) * 2019-10-31 2020-03-31 厦门昶科生物工程有限公司 一种丁酸虾青素双酯的制备方法
SG10201914033YA (en) * 2019-12-31 2021-07-29 Wilmar International Ltd Polypeptides with Lipase Activity and Uses Thereof
EP4157250A4 (de) * 2020-05-29 2024-06-19 Cerecin Inc. Verfahren zur behandlung von kindlichen spasmen mit mittelkettigen triglyceriden
WO2022140580A1 (en) 2020-12-24 2022-06-30 Orn Almarsson Xanthophyll derivatives
JP7809395B1 (ja) * 2025-02-12 2026-02-02 株式会社八代 薄膜蒸留に使用するための抽出溶媒組成物、ならびにそれを用いた抽出対象成分の分取方法および分取システム

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450819A (en) * 1965-07-12 1969-06-17 Drew Chem Corp Synthetic therapeutic fat
JPH01202261A (ja) * 1988-02-09 1989-08-15 Kyowa Hakko Kogyo Co Ltd 赤色魚用餌料と赤色魚の養殖方法
JPH07300421A (ja) * 1994-04-28 1995-11-14 Itano Reitou Kk 抗炎症剤
JPH09124470A (ja) * 1995-10-26 1997-05-13 Suntory Ltd 抗ストレス組成物
US5916791A (en) * 1995-11-24 1999-06-29 Hirschberg; Joseph Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a β--C--4--oxygenase activity for biotechnological production of (3S,3S)astaxanthin
JPH10421A (ja) * 1996-06-18 1998-01-06 Chugai Ro Co Ltd ダイコータの塗布方法
JPH11290094A (ja) * 1998-04-06 1999-10-26 Nof Corp アスタキサンチン脂肪酸エステルの製造方法
NO309386B1 (no) * 1999-04-19 2001-01-22 Norsk Hydro As Pigment

Also Published As

Publication number Publication date
KR20040103979A (ko) 2004-12-09
CA2481704C (en) 2011-06-21
EP1500645A1 (de) 2005-01-26
CN1649839A (zh) 2005-08-03
AU2003234765B2 (en) 2009-09-17
SG150385A1 (en) 2009-03-30
CN100374417C (zh) 2008-03-12
DE60328374D1 (de) 2009-08-27
AU2003234765A1 (en) 2003-11-17
MY137041A (en) 2008-12-31
IL164089A0 (en) 2005-12-18
EP1500645B1 (de) 2009-07-15
CA2481704A1 (en) 2003-11-13
JPWO2003093229A1 (ja) 2005-09-08
WO2003093229A1 (en) 2003-11-13
US20050228188A1 (en) 2005-10-13
KR100941899B1 (ko) 2010-02-11
EP1500645A4 (de) 2005-06-08

Similar Documents

Publication Publication Date Title
KR100941899B1 (ko) 아스타산틴 중쇄 지방산 에스테르, 그 제조법, 및 이들을함유하는 조성물
JP5658876B2 (ja) 大規模従属栄養培養領域にて産生される超高純度ｅｐａと極性脂質
JP4175698B2 (ja) 新規なトリグリセリド及びそれを含む組成物
EP0866874B2 (de) Prozess für die präparation von substanzen mit hohem gehalt an isomeren von konjugierte linölsäure
KR100504324B1 (ko) 도코사펜타엔산 함유물질의 이용
LT4550B (lt) Dokozaheksaeno rūgšties ir dokozapentaeno rūgšties gavimo būdas
JP2003304894A (ja) ドコサヘキサエン酸およびドコサヘキサエン酸を含む化合物
JP4283351B2 (ja) 新規な油脂組成物の製造方法および用途
WO2006054183A3 (en) Enzymatically synthesized marine phospholipids
RU2237072C2 (ru) Пигмент
JPH11290094A (ja) アスタキサンチン脂肪酸エステルの製造方法
JP2001186898A (ja) 多価不飽和脂肪酸残基をもつホスファチジルセリンの製造法
JP3483197B2 (ja) 共役リノール酸エステル、その製造法及びその利用
JP2545480B2 (ja) 機能性食品素材
JP3853767B2 (ja) 共役脂肪酸メントールエステルおよびその製造方法
JP4850153B2 (ja) 新規なトリグリセリド及びそれを含む組成物
Nakao et al. Enzymatic synthesis of astaxanthin n-octanoic acid esters
EP3677686A1 (de) Hydroxyliertes fettsäurehomopolymer und herstellungsverfahren dafür
JP2001245687A (ja) ｎ−４系及び／又はｎ−７系高度不飽和脂肪酸を含有する脂質及びその製造方法
JPH01320989A (ja) ワックスエステルの生産方法
Petel Biogeneration of lipophenols by lipases using selected substrate models
HK40026207B (en) Hydroxylated fatty acid multimers and production method thereof

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060411

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060411

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090130

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090327

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20090422

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090814

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090924

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20091016

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20091113

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121120

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121120

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131120

Year of fee payment: 4

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees