JP4963414B2 - ロドコッカスロドヒラス（ｒｈｏｄｏｃｏｃｃｕｓｒｈｏｄｏｃｈｒｏｕｓ）ｎｃｉｍｂ４１１６４菌株、およびそのニトリルヒドラターゼ産生株としての使用 - Google Patents

ロドコッカスロドヒラス（ｒｈｏｄｏｃｏｃｃｕｓｒｈｏｄｏｃｈｒｏｕｓ）ｎｃｉｍｂ４１１６４菌株、およびそのニトリルヒドラターゼ産生株としての使用 Download PDF

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Publication number
JP4963414B2
JP4963414B2 JP2006541837A JP2006541837A JP4963414B2 JP 4963414 B2 JP4963414 B2 JP 4963414B2 JP 2006541837 A JP2006541837 A JP 2006541837A JP 2006541837 A JP2006541837 A JP 2006541837A JP 4963414 B2 JP4963414 B2 JP 4963414B2
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urea
medium
biocatalyst
rhodococcus rhodochrous
alkyl derivative
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Expired - Lifetime
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Japanese (ja)
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JP2007512820A (ja
Inventor
ヒューズ，ジョナサン
アーミテージ，イボンヌ
クラー，ジャティンダー
グリーンハル，スチュアート
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Ciba Specialty Chemicals Water Treatments Ltd
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Ciba Specialty Chemicals Water Treatments Ltd
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Priority claimed from GB0422070A external-priority patent/GB0422070D0/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2006541837A 2003-12-02 2004-11-22 ロドコッカスロドヒラス（ｒｈｏｄｏｃｏｃｃｕｓｒｈｏｄｏｃｈｒｏｕｓ）ｎｃｉｍｂ４１１６４菌株、およびそのニトリルヒドラターゼ産生株としての使用 Expired - Lifetime JP4963414B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0327907.2A GB0327907D0 (en) 2003-12-02 2003-12-02 Microorganism
GB0327907.2 2003-12-02
GB0422070.3 2004-10-06
GB0422070A GB0422070D0 (en) 2004-10-06 2004-10-06 Microorganism
PCT/EP2004/013252 WO2005054456A1 (en) 2003-12-02 2004-11-22 Strain of rhodococcus rhodochrous ncimb 41164 and its use as producer of nitrile hydratase

Publications (2)

Publication Number Publication Date
JP2007512820A JP2007512820A (ja) 2007-05-24
JP4963414B2 true JP4963414B2 (ja) 2012-06-27

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JP2006541837A Expired - Lifetime JP4963414B2 (ja) 2003-12-02 2004-11-22 ロドコッカスロドヒラス（ｒｈｏｄｏｃｏｃｃｕｓｒｈｏｄｏｃｈｒｏｕｓ）ｎｃｉｍｂ４１１６４菌株、およびそのニトリルヒドラターゼ産生株としての使用

Country Status (14)

Country Link
US (2) US7575912B2 (2)
EP (1) EP1689861B1 (2)
JP (1) JP4963414B2 (2)
KR (1) KR101106943B1 (2)
AT (1) ATE532859T1 (2)
AU (1) AU2004295409B2 (2)
BR (1) BRPI0417244B1 (2)
CA (1) CA2547393C (2)
ES (1) ES2376218T3 (2)
IN (1) IN2006CH01964A (2)
MX (1) MXPA06006234A (2)
RU (1) RU2403280C2 (2)
SG (1) SG148992A1 (2)
WO (1) WO2005054456A1 (2)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0416101D0 (en) * 2004-07-19 2004-08-18 Ciba Spec Chem Water Treat Ltd Process for preparing monomers and polymers thereof
JP4970276B2 (ja) 2005-10-07 2012-07-04 三井化学株式会社 アミド化合物の製造方法
NZ599631A (en) * 2006-01-30 2013-08-30 Univ Georgia State Res Found Induction and stabilization of enzymatic activity in microorganisms
JPWO2007132601A1 (ja) * 2006-05-15 2009-09-24 三井化学株式会社 （メタ）アクリルアミドの製造方法
US8986971B2 (en) * 2006-09-22 2015-03-24 Triphase Research And Development I Corp. Salt formulations for the fermentation of marine microorganisms
AU2009224295B2 (en) * 2008-03-14 2015-01-22 Mitsubishi Chemical Corporation Process for production of amide compounds
CN102286409B (zh) * 2009-07-16 2013-04-24 浙江工业大学 紫红红球菌及其催化亚氨基二乙腈制备亚氨基二乙酸
CN102329744B (zh) * 2010-07-13 2014-04-23 中国环境科学研究院 异养型硝化细菌、包含其的生物传感器、及检测水体毒性的方法
CN103620030B (zh) * 2011-01-14 2016-06-01 三菱丽阳株式会社 微生物菌体的运输方法
BR112014020899A2 (pt) 2012-02-28 2018-05-02 Mitsubishi Rayon Co., Ltd. métodos para produzir, preservar, e ativar nitrila hidratase
RU2520870C1 (ru) * 2012-12-27 2014-06-27 Кемира Оюй Штамм бактерий rhodococcus aetherivorans bkm ac-2610d - продуцент нитрилгидратазы, способ его культивирования и способ получения акриламида
US10655152B2 (en) 2014-09-30 2020-05-19 Solenis Technologies, L.P. Method for producing an amide
BR112017005840A2 (pt) * 2014-09-30 2018-02-27 Basf Se processos para preparar uma solução aquosa de acrilamida, reduzir concentração de ácido acrílico de uma solução aquosa de acrilamida, solução aquosa de acrilamida, homopolímero ou copolímero de acrilamida, e, solução de um homopolímero e/ou copolímero de acrilamida.
WO2017055518A1 (en) * 2015-09-30 2017-04-06 Basf Se Means and methods for producing an amide compound
WO2019081003A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
MY201242A (en) 2017-10-25 2024-02-13 Basf Se Process for producing aqueous polyacrylamide solutions
WO2019081008A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS ACRYLAMIDE SOLUTION
AR113386A1 (es) 2017-10-25 2020-04-29 Basf Se Proceso y planta modular y reubicable para producir soluciones acuosas de poliacrilamida
WO2019081004A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
WO2019081323A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
AR113377A1 (es) 2017-10-25 2020-04-22 Basf Se Proceso para producir soluciones acuosas de poliacrilamida
CA3076685A1 (en) 2017-10-25 2019-05-02 Basf Se Process for producing aqueous polyacrylamide solutions
WO2020079119A1 (en) 2018-10-18 2020-04-23 Basf Se Method of providing aqueous polyacrylamide concentrates
EA202191076A1 (ru) 2018-10-18 2021-08-03 Басф Се Способ получения водного концентрата полиакриламида
CA3112658A1 (en) 2018-10-18 2020-04-23 Basf Se Process of fracturing subterranean formations
WO2020079124A1 (en) 2018-10-18 2020-04-23 Basf Se Process for producing aqueous polyacrylamide compositions
AU2019362384B2 (en) 2018-10-18 2025-01-16 Basf Se Process for producing ammonium (METH-) acrylate
RU2731289C2 (ru) * 2018-12-13 2020-09-01 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) Способ конструирования на основе бактерий рода Rhodococcus штамма-биокатализатора, обладающего нитрилазной активностью и повышенной операционной стабильностью, рекомбинантный штамм бактерий Rhodococcus rhodochrous, полученный таким способом, способ синтеза акриловой кислоты с использованием этого штамма в качестве биокатализатора
EP4055179A1 (en) * 2019-11-05 2022-09-14 Basf Se Method of storing a biocatalyst
EP4279600A4 (en) 2021-02-10 2025-06-11 Mitsubishi Chemical Corporation Improved nitrile hydratase reactivity using aldehyde
WO2023041515A2 (en) 2021-09-15 2023-03-23 Basf Se Method for preparing an aqueous (meth) acrylamide solution
KR20250156762A (ko) 2023-03-17 2025-11-03 미쯔비시 케미컬 주식회사 아미드 화합물의 제조 방법
KR20250138785A (ko) 2023-03-17 2025-09-22 미쯔비시 케미컬 주식회사 아미드 화합물의 제조 방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3281247A (en) * 1963-12-16 1966-10-25 Commercial Solvents Corp Process for producing monosodium glutamate
JPS62259586A (ja) * 1986-05-02 1987-11-11 Nitto Chem Ind Co Ltd ニトリル水和活性の保持方法
DD274631A5 (de) 1987-09-18 1989-12-27 Kk Verfahren zur biologischen herstellung von amiden
CZ280901B6 (cs) * 1988-10-06 1996-05-15 Hideaki Yamada Způsob kultivace bakterií
JPH0753103B2 (ja) * 1988-10-06 1995-06-07 秀明 山田 細菌の培養法
AU627648B2 (en) 1990-02-28 1992-08-27 Teruhiko Beppu Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant
JP3009421B2 (ja) * 1990-02-28 2000-02-14 秀明 山田 有機酸の生物学的製造法
SU1731814A1 (ru) 1990-05-17 1992-05-07 Саратовский филиал Всесоюзного научно-исследовательского института генетики и селекции промышленныхмикроорганизмов Штамм бактерий RноDососсUS RноDоснRоUS - продуцент нитрилгидратазы
RU2053300C1 (ru) 1993-12-17 1996-01-27 Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штамм бактерий rhodococcus rhodochrous - продуцент нитрилгидратазы
JP3014262B2 (ja) 1994-01-11 2000-02-28 三菱レイヨン株式会社 生体触媒固定化用担体および固定化生体触媒
JP3163224B2 (ja) * 1994-10-14 2001-05-08 三菱レイヨン株式会社 菌体または固定化菌体の懸濁液の保存方法
WO1997006248A1 (en) * 1995-08-09 1997-02-20 Allied Colloids Limited Processes for the production of amidase
RU2077588C1 (ru) 1996-01-16 1997-04-20 Государственное унитарное предприятие Саратовский научно-исследовательский институт биокатализа Способ получения акриламида
US6368804B1 (en) 1999-07-12 2002-04-09 E. I. Du Pont De Nemours & Company Method for stabilizing nitrilase activity and preserving microbial cells
CN1296487C (zh) 2000-12-20 2007-01-24 大野绿水株式会社 利用微生物催化剂生产酰胺化合物的方法
DE10120546A1 (de) * 2001-04-26 2002-10-31 Stockhausen Chem Fab Gmbh Verfahren zur Herstellung einer wässrigen Acrylamidlösung mit einem Biokatalysator
DE10120550A1 (de) * 2001-04-26 2002-10-31 Stockhausen Chem Fab Gmbh Verfahren zur Herstellung einer wässrigen Acrylamidlösung mit einem Biokatalysator
US7816106B2 (en) * 2003-12-02 2010-10-19 Ciba Specialty Chemicals Water Treatments Ltd. Manufacture of amides

Also Published As

Publication number Publication date
SG148992A1 (en) 2009-01-29
ES2376218T3 (es) 2012-03-12
AU2004295409B2 (en) 2010-07-29
BRPI0417244A (pt) 2007-03-06
JP2007512820A (ja) 2007-05-24
ATE532859T1 (de) 2011-11-15
AU2004295409A1 (en) 2005-06-16
EP1689861B1 (en) 2011-11-09
US20070077634A1 (en) 2007-04-05
US20090269822A1 (en) 2009-10-29
WO2005054456A1 (en) 2005-06-16
RU2403280C2 (ru) 2010-11-10
US7575912B2 (en) 2009-08-18
IN2006CH01964A (2) 2007-06-08
KR101106943B1 (ko) 2012-01-19
US8153406B2 (en) 2012-04-10
CA2547393A1 (en) 2005-06-16
KR20060123248A (ko) 2006-12-01
CA2547393C (en) 2013-08-27
RU2006123429A (ru) 2008-01-10
BRPI0417244B1 (pt) 2015-05-26
MXPA06006234A (es) 2006-07-31
EP1689861A1 (en) 2006-08-16

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