JP6177992B2 - エンパグリフロジンの治療的使用 - Google Patents

エンパグリフロジンの治療的使用 Download PDF

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JP6177992B2
JP6177992B2 JP2016505816A JP2016505816A JP6177992B2 JP 6177992 B2 JP6177992 B2 JP 6177992B2 JP 2016505816 A JP2016505816 A JP 2016505816A JP 2016505816 A JP2016505816 A JP 2016505816A JP 6177992 B2 JP6177992 B2 JP 6177992B2
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patient
diabetes
empagliflozin
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patients
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JP2016515600A (ja
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ウリ ブロードル
ウリ ブロードル
エイナッテン マクシミリアン フォン
エイナッテン マクシミリアン フォン
スリーラジ マチャ
スリーラジ マチャ
ハンス−ユルゲン ヴォーレ
ハンス−ユルゲン ヴォーレ
Original Assignee
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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Application filed by ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング, ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング filed Critical ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2016505816A 2013-04-05 2014-04-03 エンパグリフロジンの治療的使用 Active JP6177992B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361808804P 2013-04-05 2013-04-05
US61/808,804 2013-04-05
CA2812519A CA2812519A1 (en) 2013-04-05 2013-04-10 Pharmaceutical composition, methods for treating and uses thereof
CA2812519 2013-04-10
US201361908991P 2013-11-26 2013-11-26
US61/908,991 2013-11-26
PCT/EP2014/056657 WO2014161919A1 (en) 2013-04-05 2014-04-03 Therapeutic uses of empagliflozin

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017135958A Division JP6431959B2 (ja) 2013-04-05 2017-07-12 エンパグリフロジンの治療的使用

Publications (2)

Publication Number Publication Date
JP2016515600A JP2016515600A (ja) 2016-05-30
JP6177992B2 true JP6177992B2 (ja) 2017-08-09

Family

ID=51787230

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016505816A Active JP6177992B2 (ja) 2013-04-05 2014-04-03 エンパグリフロジンの治療的使用

Country Status (15)

Country Link
US (2) US12433906B2 (pl)
EP (2) EP2981271B1 (pl)
JP (1) JP6177992B2 (pl)
KR (3) KR102318213B1 (pl)
CN (2) CN105377267A (pl)
AU (1) AU2014247092B2 (pl)
CA (3) CA2812519A1 (pl)
DK (1) DK2981271T3 (pl)
EA (1) EA033397B1 (pl)
LT (1) LT2981271T (pl)
MX (2) MX375476B (pl)
PL (1) PL2981271T3 (pl)
RS (1) RS58097B1 (pl)
SI (1) SI2981271T1 (pl)
WO (1) WO2014161919A1 (pl)

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Publication number Priority date Publication date Assignee Title
MY161472A (en) 2009-02-13 2017-04-14 Boehringer Ingelheim Int Sglt-2 inhibitor for treating type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance or hyperglycemia
US11813275B2 (en) 2013-04-05 2023-11-14 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
US20140303097A1 (en) 2013-04-05 2014-10-09 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
HRP20190101T1 (hr) 2013-04-05 2019-03-08 Boehringer Ingelheim International Gmbh Terapeutske uporabe empagliflozina
CA2812519A1 (en) 2013-04-05 2014-10-05 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
KR102309654B1 (ko) 2013-04-18 2021-10-08 베링거 인겔하임 인터내셔날 게엠베하 약제학적 조성물, 치료 방법 및 이의 용도
CN105769782A (zh) * 2014-12-23 2016-07-20 中美华世通生物医药科技（武汉）有限公司 恩格列净片及其制备方法和用途
CN106880595A (zh) * 2015-12-10 2017-06-23 常州方楠医药技术有限公司 一种无定型依帕列净的固体分散体及其制备方法
CA3039745A1 (en) * 2016-11-10 2018-05-17 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
US11617754B2 (en) 2017-10-02 2023-04-04 Poxel Sa Methods of treating heart failure with preserved ejection fraction
LT3804714T (lt) 2018-05-31 2025-03-10 Hua Medicine (Shanghai) Ltd. Farmacinis derinys ir kompozicija, ir derinio preparatas, kurio sudėtyje yra gliukokinazės aktyvatorius ir biguanido hipoglikeminis vaistas, taip pat jų gamybos būdas ir panaudojimas
MX2020013210A (es) * 2018-06-06 2021-02-26 Metavant Sciences Gmbh Metodos de tratamiento de sujetos que padecen diabetes con enfermedad renal cronica.
EP3806828A1 (en) 2018-06-14 2021-04-21 Poxel Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes
CN110141555A (zh) * 2019-06-21 2019-08-20 江苏豪森药业集团有限公司 一种恩格列净片及其制备方法
CN110721170A (zh) * 2019-10-24 2020-01-24 安徽九华华源药业有限公司 一种恩格列净片剂及其制备方法
WO2022065895A1 (ko) * 2020-09-24 2022-03-31 동아에스티 주식회사 Sglt-2 억제제인 엠파글리플로진 유도체의 신규염 및 염의 수화물
WO2026018268A1 (en) * 2024-07-13 2026-01-22 Zydus Lifesciences Limited Treatment of diabetes and diabetes induced ckd and the associated symptoms

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