JP7064214B2 - 抗体回避性ウイルスベクターのための方法および組成物 - Google Patents

抗体回避性ウイルスベクターのための方法および組成物 Download PDF

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JP7064214B2
JP7064214B2 JP2018515949A JP2018515949A JP7064214B2 JP 7064214 B2 JP7064214 B2 JP 7064214B2 JP 2018515949 A JP2018515949 A JP 2018515949A JP 2018515949 A JP2018515949 A JP 2018515949A JP 7064214 B2 JP7064214 B2 JP 7064214B2
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amino acid
aav
positions
seq
capsid protein
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JP2018528253A (ja
JP2018528253A5 (2
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アソカン，アラヴィンド
アグバンジェ‐マッケンナ，メイヴィス
ツェ，ロン・ピン・ヴィクター
ガーダ，ブリトニー
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ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル
ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド
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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6027—Vectors comprising as targeting moiety peptide derived from defined protein from viruses ssDNA viruses

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  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2018515949A 2015-09-28 2016-09-28 抗体回避性ウイルスベクターのための方法および組成物 Expired - Fee Related JP7064214B2 (ja)

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JP2022011956A JP7390693B2 (ja) 2015-09-28 2022-01-28 抗体回避性ウイルスベクターのための方法および組成物
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US201562234016P 2015-09-28 2015-09-28
US62/234,016 2015-09-28
PCT/US2016/054143 WO2017058892A2 (en) 2015-09-28 2016-09-28 Methods and compositions for antibody-evading virus vectors

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US (4) US10745447B2 (2)
EP (2) EP3831842A1 (2)
JP (3) JP7064214B2 (2)
CN (2) CN114606267A (2)
AU (2) AU2016332821B2 (2)
BR (1) BR112018003665A2 (2)
CA (1) CA2996420A1 (2)
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