JP7432533B2 - 高純度ステビオール配糖体 - Google Patents

高純度ステビオール配糖体 Download PDF

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Publication number
JP7432533B2
JP7432533B2 JP2020573088A JP2020573088A JP7432533B2 JP 7432533 B2 JP7432533 B2 JP 7432533B2 JP 2020573088 A JP2020573088 A JP 2020573088A JP 2020573088 A JP2020573088 A JP 2020573088A JP 7432533 B2 JP7432533 B2 JP 7432533B2
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Japan
Prior art keywords
rebaudioside
udp
stevioside
glucosyltransferase
steviolbioside
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JP2020573088A
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English (en)
Japanese (ja)
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JP2021518163A (ja
Inventor
マルコスヤン、アベチク
ラマンダッハ、サラバナン、エイ／エル
ビン ハシム、モハマド アフザール
ビン ナウィ、カイルール ニザーム
チャウ、シュウ、イン
プルカヤスタ、シッダールタ
プティ、マーシァ
Original Assignee
ピュアサークル ユーエスエー インコーポレイテッド
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Priority claimed from PCT/US2018/026920 external-priority patent/WO2019177634A1/fr
Application filed by ピュアサークル ユーエスエー インコーポレイテッド filed Critical ピュアサークル ユーエスエー インコーポレイテッド
Publication of JP2021518163A publication Critical patent/JP2021518163A/ja
Priority to JP2024015867A priority Critical patent/JP2024033006A/ja
Application granted granted Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/88—Taste or flavour enhancing agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C12N9/1062—Sucrose synthase (2.4.1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2020573088A 2018-03-16 2019-03-15 高純度ステビオール配糖体 Active JP7432533B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024015867A JP2024033006A (ja) 2018-03-16 2024-02-05 高純度ステビオール配糖体

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862644065P 2018-03-16 2018-03-16
US62/644,065 2018-03-16
US201862644407P 2018-03-17 2018-03-17
US62/644,407 2018-03-17
USPCT/US2018/026920 2018-04-10
PCT/US2018/026920 WO2019177634A1 (fr) 2018-03-16 2018-04-10 Glycosides de stéviol de haute pureté
US201962802111P 2019-02-06 2019-02-06
US62/802,111 2019-02-06
PCT/US2019/022581 WO2019178541A1 (fr) 2018-03-16 2019-03-15 Glycosides de stéviol de haute pureté

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024015867A Division JP2024033006A (ja) 2018-03-16 2024-02-05 高純度ステビオール配糖体

Publications (2)

Publication Number Publication Date
JP2021518163A JP2021518163A (ja) 2021-08-02
JP7432533B2 true JP7432533B2 (ja) 2024-02-16

Family

ID=67908464

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020573088A Active JP7432533B2 (ja) 2018-03-16 2019-03-15 高純度ステビオール配糖体
JP2024015867A Pending JP2024033006A (ja) 2018-03-16 2024-02-05 高純度ステビオール配糖体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024015867A Pending JP2024033006A (ja) 2018-03-16 2024-02-05 高純度ステビオール配糖体

Country Status (8)

Country Link
EP (1) EP3765472A4 (fr)
JP (2) JP7432533B2 (fr)
KR (1) KR20200132940A (fr)
CN (1) CN112513059A (fr)
AU (2) AU2019236279B2 (fr)
CA (1) CA3094205A1 (fr)
MX (1) MX2020009635A (fr)
WO (1) WO2019178541A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220232860A1 (en) * 2019-05-17 2022-07-28 Purecircle Usa Inc. Stevia flavor compositions
WO2021226417A1 (fr) * 2020-05-07 2021-11-11 The Coca-Cola Company Boissons comprenant du rébaudioside am et du rébaudioside m à saveur améliorée
CN114045273B (zh) * 2021-11-15 2022-07-22 四川大学 糖基转移酶OsUGT91C1突变体及其应用
CN114315926B (zh) * 2022-01-04 2024-02-06 东台市浩瑞生物科技有限公司 一种多次高温裂解法生产甜菊双糖苷的工艺方法
US20260009063A1 (en) * 2022-07-07 2026-01-08 Purecircle Sdn. Bhd. High-purity steviol glycosides
CN117106000A (zh) * 2023-07-17 2023-11-24 华南理工大学 一种甜菊糖苷聚集体及其制备方法和应用
CN117752583B (zh) * 2023-12-26 2025-12-19 江苏雪豹日化有限公司 一种无水漱口水及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018071744A1 (fr) 2016-10-14 2018-04-19 Conagen Inc. Production biosynthétique de glycosides de stéviol et procédés associés
WO2018164747A1 (fr) 2017-03-06 2018-09-13 Conagen Inc. Production biosynthétique du glycoside de stéviol rébaudiosine d4 à partir de rébaudiosine e
WO2019006244A1 (fr) 2017-06-30 2019-01-03 Conagen Inc. Hydrolyse de glycosides de stéviol par la bêta-glucosidase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5307730B2 (ja) * 2007-01-22 2013-10-02 カーギル・インコーポレイテッド 溶媒／貧溶媒晶析を用いる精製レバウディオサイドａ組成物の製法
US9752174B2 (en) * 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
EP3215629B1 (fr) * 2014-11-05 2024-08-07 Manus Bio Inc. Production microbienne de glycosides de stéviol
US10058112B2 (en) * 2014-11-21 2018-08-28 Eco Sweeteners Llc Sweetener composition including enzymatically processed stevia and method of manufacturing
JP6793957B2 (ja) * 2015-04-14 2020-12-02 コナゲン インコーポレイテッド 改変された全細胞触媒を用いたノンカロリー甘味料の生成
MX2018006599A (es) * 2015-11-30 2018-09-21 Purecircle Sdn Bhd Proceso para producir glicosidos de esteviol de alta pureza.
AU2017345605B2 (en) * 2016-10-20 2022-04-14 The Coca-Cola Company Diterpene glycosides isolated from Stevia, compositions and methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018071744A1 (fr) 2016-10-14 2018-04-19 Conagen Inc. Production biosynthétique de glycosides de stéviol et procédés associés
WO2018164747A1 (fr) 2017-03-06 2018-09-13 Conagen Inc. Production biosynthétique du glycoside de stéviol rébaudiosine d4 à partir de rébaudiosine e
WO2019006244A1 (fr) 2017-06-30 2019-01-03 Conagen Inc. Hydrolyse de glycosides de stéviol par la bêta-glucosidase

Also Published As

Publication number Publication date
BR112020018972A2 (pt) 2021-01-05
EP3765472A4 (fr) 2022-01-19
CN112513059A (zh) 2021-03-16
CA3094205A1 (fr) 2019-09-19
AU2019236279B2 (en) 2023-11-23
KR20200132940A (ko) 2020-11-25
JP2021518163A (ja) 2021-08-02
AU2024201079A1 (en) 2024-03-07
MX2020009635A (es) 2021-02-16
AU2024201079B2 (en) 2026-04-09
JP2024033006A (ja) 2024-03-12
WO2019178541A1 (fr) 2019-09-19
AU2019236279A1 (en) 2020-10-08
EP3765472A1 (fr) 2021-01-20

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