JPH01101878A - 全細胞酵素を細胞成長と同時に固定化する方法 - Google Patents

全細胞酵素を細胞成長と同時に固定化する方法

Info

Publication number: JPH01101878A
Authority: JP; Japan
Prior art keywords: reactor; tube; cells; silicone tube; polypropylene
Prior art date: 1987-10-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP63136634A

Other languages

English (en)

Japanese (ja)

Other versions

JPH0547193B2 (de

Inventor

Ho Nam Chang

ホー　ナム　チャン

Pong-Hyon Jeong

ボン　ヒュン　チュン

Un-Ha Hwang

ウン　ハ　フウァン

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Korea Advanced Institute of Science and Technology KAIST

Original Assignee

Korea Advanced Institute of Science and Technology KAIST

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-14

Filing date

1988-06-02

Publication date

1989-04-19

1988-06-02 Application filed by Korea Advanced Institute of Science and Technology KAIST filed Critical Korea Advanced Institute of Science and Technology KAIST

1989-04-19 Publication of JPH01101878A publication Critical patent/JPH01101878A/ja

1993-07-16 Publication of JPH0547193B2 publication Critical patent/JPH0547193B2/ja

Status Granted legal-status Critical Current

Links

102000004190 Enzymes Human genes 0.000 title claims abstract description 16
108090000790 Enzymes Proteins 0.000 title claims abstract description 16
238000000034 method Methods 0.000 title claims abstract description 15
230000010261 cell growth Effects 0.000 title claims description 3
229920001296 polysiloxane Polymers 0.000 claims abstract description 18
239000004743 Polypropylene Substances 0.000 claims abstract description 17
-1 polypropylene Polymers 0.000 claims abstract description 17
229920001155 polypropylene Polymers 0.000 claims abstract description 17
235000015097 nutrients Nutrition 0.000 claims abstract description 12
239000007788 liquid Substances 0.000 claims abstract description 10
238000006911 enzymatic reaction Methods 0.000 claims abstract description 9
239000000758 substrate Substances 0.000 claims abstract description 7
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 4
229910052760 oxygen Inorganic materials 0.000 claims description 4
239000001301 oxygen Substances 0.000 claims description 4
230000003100 immobilizing effect Effects 0.000 abstract description 5
239000012528 membrane Substances 0.000 abstract description 5
230000002255 enzymatic effect Effects 0.000 abstract description 2
238000006243 chemical reaction Methods 0.000 description 5
229920002379 silicone rubber Polymers 0.000 description 5
239000004945 silicone rubber Substances 0.000 description 5
239000000243 solution Substances 0.000 description 5
238000004113 cell culture Methods 0.000 description 4
238000010586 diagram Methods 0.000 description 4
239000011521 glass Substances 0.000 description 4
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
238000012258 culturing Methods 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
229910052710 silicon Inorganic materials 0.000 description 3
239000010703 silicon Substances 0.000 description 3
HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 2
NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 description 2
229930091371 Fructose Natural products 0.000 description 2
239000005715 Fructose Substances 0.000 description 2
RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 2
241000187747 Streptomyces Species 0.000 description 2
238000010924 continuous production Methods 0.000 description 2
230000000694 effects Effects 0.000 description 2
238000002474 experimental method Methods 0.000 description 2
239000000284 extract Substances 0.000 description 2
238000011081 inoculation Methods 0.000 description 2
229920000936 Agarose Polymers 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
241000186146 Brevibacterium Species 0.000 description 1
101100283604 Caenorhabditis elegans pigk-1 gene Proteins 0.000 description 1
241000183766 Medetera Species 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
235000010410 calcium alginate Nutrition 0.000 description 1
229960002681 calcium alginate Drugs 0.000 description 1
239000000648 calcium alginate Substances 0.000 description 1
OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 1
229940041514 candida albicans extract Drugs 0.000 description 1
239000000969 carrier Substances 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
238000000855 fermentation Methods 0.000 description 1
230000004151 fermentation Effects 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
238000006317 isomerization reaction Methods 0.000 description 1
230000007774 longterm Effects 0.000 description 1
239000000463 material Substances 0.000 description 1
239000000203 mixture Substances 0.000 description 1
WIIZEEPFHXAUND-UHFFFAOYSA-N n-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide;hydron;chloride Chemical compound Cl.COC1=C(OC)C(OC)=CC(C(=O)NCC=2C=CC(OCCN(C)C)=CC=2)=C1 WIIZEEPFHXAUND-UHFFFAOYSA-N 0.000 description 1
229920002401 polyacrylamide Polymers 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
239000002689 soil Substances 0.000 description 1
210000005239 tubule Anatomy 0.000 description 1
239000012138 yeast extract Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/24—Apparatus for enzymology or microbiology tube or bottle type

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Sustainable Development (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

JP63136634A 1987-10-14 1988-06-02 全細胞酵素を細胞成長と同時に固定化する方法 Granted JPH01101878A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR1987-11375		1987-10-14
KR1019840011375A KR890004018B1 (ko)	1987-10-14	1987-10-14	전세포 효소를 세포 성장과 동시에 고정화하는 방법

Publications (2)

Publication Number	Publication Date
JPH01101878A true JPH01101878A (ja)	1989-04-19
JPH0547193B2 JPH0547193B2 (de)	1993-07-16

Family

ID=19265155

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP63136634A Granted JPH01101878A (ja)	1987-10-14	1988-06-02	全細胞酵素を細胞成長と同時に固定化する方法

Country Status (2)

Country	Link
JP (1)	JPH01101878A (de)
KR (1)	KR890004018B1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH02276565A (ja) *	1989-04-18	1990-11-13	Japanese Res & Dev Assoc Bio Reactor Syst Food Ind	連続酵素反応装置

1987
- 1987-10-14 KR KR1019840011375A patent/KR890004018B1/ko not_active Expired
1988
- 1988-06-02 JP JP63136634A patent/JPH01101878A/ja active Granted

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH02276565A (ja) *	1989-04-18	1990-11-13	Japanese Res & Dev Assoc Bio Reactor Syst Food Ind	連続酵素反応装置

Also Published As

Publication number	Publication date
KR890006809A (ko)	1989-06-16
KR890004018B1 (ko)	1989-10-16
JPH0547193B2 (de)	1993-07-16

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