JPH0547193B2 - - Google Patents

Info

Publication number: JPH0547193B2
Authority: JP; Japan
Prior art keywords: tube; reactor; polypropylene; cells; silicon
Prior art date: 1987-10-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP63136634A

Other languages

English (en)

Japanese (ja)

Other versions

JPH01101878A (ja

Inventor

Namu Chan Hoo

Hyun Chun Bon

Ha Fuan Un

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Korea Advanced Institute of Science and Technology KAIST

Original Assignee

Korea Advanced Institute of Science and Technology KAIST

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-14

Filing date

1988-06-02

Publication date

1993-07-16

1988-06-02 Application filed by Korea Advanced Institute of Science and Technology KAIST filed Critical Korea Advanced Institute of Science and Technology KAIST

1989-04-19 Publication of JPH01101878A publication Critical patent/JPH01101878A/ja

1993-07-16 Publication of JPH0547193B2 publication Critical patent/JPH0547193B2/ja

Status Granted legal-status Critical Current

Links

108090000790 Enzymes Proteins 0.000 claims description 17
102000004190 Enzymes Human genes 0.000 claims description 17
239000004743 Polypropylene Substances 0.000 claims description 15
-1 polypropylene Polymers 0.000 claims description 15
229920001155 polypropylene Polymers 0.000 claims description 15
XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 13
229910052710 silicon Inorganic materials 0.000 claims description 13
239000010703 silicon Substances 0.000 claims description 13
235000015097 nutrients Nutrition 0.000 claims description 11
238000000034 method Methods 0.000 claims description 9
238000006911 enzymatic reaction Methods 0.000 claims description 8
239000007788 liquid Substances 0.000 claims description 8
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
239000000758 substrate Substances 0.000 claims description 6
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 5
229910052760 oxygen Inorganic materials 0.000 claims description 5
239000001301 oxygen Substances 0.000 claims description 5
229920001296 polysiloxane Polymers 0.000 claims description 5
230000000694 effects Effects 0.000 claims description 4
239000011521 glass Substances 0.000 description 8
238000004113 cell culture Methods 0.000 description 7
238000010586 diagram Methods 0.000 description 5
239000000243 solution Substances 0.000 description 5
238000006243 chemical reaction Methods 0.000 description 4
229920002379 silicone rubber Polymers 0.000 description 4
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
230000003100 immobilizing effect Effects 0.000 description 3
238000011081 inoculation Methods 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
239000012528 membrane Substances 0.000 description 3
HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 2
NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 description 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
241000187747 Streptomyces Species 0.000 description 2
229940041514 candida albicans extract Drugs 0.000 description 2
238000010924 continuous production Methods 0.000 description 2
238000012258 culturing Methods 0.000 description 2
239000008103 glucose Substances 0.000 description 2
239000004945 silicone rubber Substances 0.000 description 2
239000012138 yeast extract Substances 0.000 description 2
229920000936 Agarose Polymers 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
241000186146 Brevibacterium Species 0.000 description 1
102000008186 Collagen Human genes 0.000 description 1
108010035532 Collagen Proteins 0.000 description 1
229930091371 Fructose Natural products 0.000 description 1
RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
239000005715 Fructose Substances 0.000 description 1
239000004098 Tetracycline Substances 0.000 description 1
108700040099 Xylose isomerases Proteins 0.000 description 1
PYMYPHUHKUWMLA-VPENINKCSA-N aldehydo-D-xylose Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-VPENINKCSA-N 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
210000001601 blood-air barrier Anatomy 0.000 description 1
235000010410 calcium alginate Nutrition 0.000 description 1
229960002681 calcium alginate Drugs 0.000 description 1
239000000648 calcium alginate Substances 0.000 description 1
OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 1
239000000969 carrier Substances 0.000 description 1
230000010261 cell growth Effects 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
230000002255 enzymatic effect Effects 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
230000007774 longterm Effects 0.000 description 1
239000000463 material Substances 0.000 description 1
229920002401 polyacrylamide Polymers 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
238000000746 purification Methods 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000002689 soil Substances 0.000 description 1
229960002180 tetracycline Drugs 0.000 description 1
229930101283 tetracycline Natural products 0.000 description 1
235000019364 tetracycline Nutrition 0.000 description 1
150000003522 tetracyclines Chemical class 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/24—Apparatus for enzymology or microbiology tube or bottle type

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Sustainable Development (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

JP63136634A 1987-10-14 1988-06-02 全細胞酵素を細胞成長と同時に固定化する方法 Granted JPH01101878A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR1987-11375		1987-10-14
KR1019840011375A KR890004018B1 (ko)	1987-10-14	1987-10-14	전세포 효소를 세포 성장과 동시에 고정화하는 방법

Publications (2)

Publication Number	Publication Date
JPH01101878A JPH01101878A (ja)	1989-04-19
JPH0547193B2 true JPH0547193B2 (de)	1993-07-16

Family

ID=19265155

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP63136634A Granted JPH01101878A (ja)	1987-10-14	1988-06-02	全細胞酵素を細胞成長と同時に固定化する方法

Country Status (2)

Country	Link
JP (1)	JPH01101878A (de)
KR (1)	KR890004018B1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH02276565A (ja) *	1989-04-18	1990-11-13	Japanese Res & Dev Assoc Bio Reactor Syst Food Ind	連続酵素反応装置

1987
- 1987-10-14 KR KR1019840011375A patent/KR890004018B1/ko not_active Expired
1988
- 1988-06-02 JP JP63136634A patent/JPH01101878A/ja active Granted

Also Published As

Publication number	Publication date
KR890006809A (ko)	1989-06-16
KR890004018B1 (ko)	1989-10-16
JPH01101878A (ja)	1989-04-19

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