JPH0114906Y2 - - Google Patents
Info
- Publication number
- JPH0114906Y2 JPH0114906Y2 JP11092785U JP11092785U JPH0114906Y2 JP H0114906 Y2 JPH0114906 Y2 JP H0114906Y2 JP 11092785 U JP11092785 U JP 11092785U JP 11092785 U JP11092785 U JP 11092785U JP H0114906 Y2 JPH0114906 Y2 JP H0114906Y2
- Authority
- JP
- Japan
- Prior art keywords
- carbon dioxide
- pump
- biological
- biological gas
- valve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 52
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 26
- 239000001569 carbon dioxide Substances 0.000 claims description 25
- 238000010521 absorption reaction Methods 0.000 claims description 13
- 238000005259 measurement Methods 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 238000005070 sampling Methods 0.000 claims description 2
- 239000007789 gas Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000004868 gas analysis Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 239000010421 standard material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Description
【考案の詳細な説明】
本考案は熱伝導度法を用いた生体炭酸ガス、特
に呼気中炭酸ガス濃度測定装置に関するものであ
る。[Detailed Description of the Invention] The present invention relates to a device for measuring biological carbon dioxide, particularly exhaled carbon dioxide concentration, using a thermal conductivity method.
呼気中その生体ガス中の炭酸ガス濃度を測定す
る場合に問題となるのはCO2トレーサビリテイの
よりどころとなる標準物質がなく、したがつて炭
酸ガスの絶対定量法といえるものが存在しないこ
とである。従来の呼気中炭酸ガス濃度、又は血中
炭酸ガス濃度測定方法としては、炭酸ガスの分圧
によつて生じる水素イオン濃度の測定、すなわち
PHメータの読みからガス濃度を換算して求める
のが一般的であり、ガスクロマトグラフ法によつ
ても可能であることが知られている。 The problem when measuring the concentration of carbon dioxide in exhaled biological gases is that there is no standard material that can be used as a basis for CO2 traceability, and therefore there is no method that can be called an absolute quantitative method for carbon dioxide. It is. The conventional method for measuring exhaled breath carbon dioxide concentration or blood carbon dioxide concentration is to measure the hydrogen ion concentration generated by the partial pressure of carbon dioxide, i.e.
It is common to calculate the gas concentration from the readings of a PH meter, and it is known that this can also be done by gas chromatography.
本考案は上記のような方式とは異り、有機物質
構成元素分析装置において適用されるトレーサビ
リテイの概念を取入れ、かつその実績を裏付けと
して絶対炭酸ガス分析法の確立ともいえる熱伝導
度法による生体炭酸ガス測定装置を提供しようと
するものである。 The present invention differs from the above-mentioned methods by incorporating the concept of traceability applied in organic substance constituent element analyzers, and based on its track record, it uses the thermal conductivity method, which can be said to be the establishment of an absolute carbon dioxide gas analysis method. The present invention aims to provide a biological carbon dioxide measuring device.
すなわち本考案の装置は測定値の自己積分を可
能にするポンプシステムと、少なくとも水吸収管
並びに炭酸ガス吸収管を有する測定及び排気流路
と、前記炭酸ガス吸入管の入口側及び出口側流路
に挿入された一対のセル室からなる熱伝導度検出
器とを含むものである。この構成によれば、炭酸
ガス吸収管の入口側及び出口側における生体ガス
試料の絶対的なCO2差を検出することによる高精
度のCO2分折を可能にするものである。 That is, the device of the present invention includes a pump system that enables self-integration of measured values, a measurement and exhaust channel having at least a water absorption pipe and a carbon dioxide absorption pipe, and a flow channel on the inlet side and outlet side of the carbon dioxide suction pipe. and a thermal conductivity detector consisting of a pair of cell chambers inserted into the thermal conductivity detector. According to this configuration, highly accurate CO 2 analysis is possible by detecting the absolute CO 2 difference between the biological gas sample on the inlet side and the outlet side of the carbon dioxide absorption tube.
図は本考案の流路構成の実施例を示すもので、
１は生体ガス試料採取口、２及び３は吸入用開閉
弁、４は全封型シリンタからなるポンプ、５，６
は排出用開閉弁であり、ポンプの一端は開閉弁２
及び５に、他端は開閉弁３及び６にそれぞれ導か
れている。排出用開閉弁５及び６の下流側は一括
して測定及び排気流路７に接続される。この測定
及び排気流路７には水吸収管８、炭酸ガス吸収管
９及び遅延コイル１０が挿入されている。測定及
び排出流路７にはさらに炭酸ガス吸収管９の入口
側及び出口側において一対の熱伝導度セル１１及
び１２を挿入し、これらのセル１１，１２は記録
計１３に接続されて、それらの検出信号差を記録
する熱伝導度式炭酸ガス分析計を構成している。 The figure shows an example of the flow path configuration of the present invention.
1 is a biological gas sample collection port, 2 and 3 are intake valves, 4 is a pump consisting of a completely sealed cylinder, 5, 6
is a discharge on-off valve, and one end of the pump is on-off valve 2.
and 5, the other ends of which are led to on-off valves 3 and 6, respectively. The downstream sides of the discharge on-off valves 5 and 6 are collectively connected to a measurement and exhaust flow path 7. A water absorption tube 8, a carbon dioxide absorption tube 9, and a delay coil 10 are inserted into this measurement and exhaust flow path 7. A pair of thermal conductivity cells 11 and 12 are further inserted into the measurement and discharge channel 7 at the inlet and outlet sides of the carbon dioxide absorption tube 9, and these cells 11 and 12 are connected to a recorder 13 to This constitutes a thermal conductivity type carbon dioxide gas analyzer that records the difference in detected signals.
ポンプ４内には対称的な室Ａ及びＢを形成する
ためのピストン１４が配置されている。１５はピ
ストン１４のストローク駆動機構であり、開閉弁
２，３，５及び６とともにタイマー１６で制御さ
れるようになつている。 A piston 14 is arranged in the pump 4 for forming symmetrical chambers A and B. 15 is a stroke drive mechanism for the piston 14, which is controlled by a timer 16 together with the on-off valves 2, 3, 5, and 6.
本考案の炭酸ガス測定装置は上記のように構成
されているので、たとえば吸入用開閉弁２、及び
排出用開閉弁６を開き、他の開閉弁３、及び５を
閉じた状態においてピストン１４を図の左端から
右端に向かつて駆動すると、室Ａには採取口１、
開閉弁２を介して呼気試料が導入されるととも
に、室Ｂにすでに収容された呼気試料は開閉弁６
を介して測定及び排出流路７に流入する。このピ
ストン１４のストローク時間（片道）と、それに
続くピストン停止時間とはタイマー１６により設
定され、室内、この場合Ａに吸入された呼気試料
の均一混合をはかるとともに、ポンプ温度への順
応を行なうようになつている。 Since the carbon dioxide measuring device of the present invention is configured as described above, for example, the piston 14 is opened with the intake on-off valve 2 and the exhaust on-off valve 6 opened, and the other on-off valves 3 and 5 closed. When driven from the left end to the right end of the figure, chamber A has sampling port 1,
The exhaled breath sample is introduced through the on-off valve 2, and the exhaled breath sample already stored in the chamber B is introduced through the on-off valve 6.
It flows into the measurement and discharge channel 7 via. The stroke time (one way) of the piston 14 and the subsequent piston stop time are set by a timer 16 to ensure uniform mixing of the exhaled breath sample inhaled into the room, in this case A, and to adapt to the pump temperature. It's getting old.
上のように均一相として最大容積となつた室Ａ
又はＢに導入された試料ガスは開閉弁３及び５又
は開閉弁２及び６を開くことにより、均一相とし
て測定及び排出流路７に導入されることとなり、
熱伝導度セル１１及び１２の差信号はこの流通時
において理想的には一定レベル（平均値）の信号
として記録され、そのピーク面積はレベル高さに
持続時間を掛けることにより記録計１３にきわめ
て容易に記録することができる。しかもポンプト
スローク時間が一定であるため、持続時間は定数
となり、結局記録前のピークの高さによつて直ち
に炭酸ガス濃度が読み取られるわけである。 As shown above, chamber A has the maximum volume as a homogeneous phase.
Or, by opening the on-off valves 3 and 5 or the on-off valves 2 and 6, the sample gas introduced into B will be introduced into the measurement and discharge flow path 7 as a homogeneous phase,
The difference signal between the thermal conductivity cells 11 and 12 is ideally recorded as a signal at a constant level (average value) during this flow, and its peak area can be determined by multiplying the level height by the duration. Can be easily recorded. Moreover, since the pump to stroke time is constant, the duration is constant, and after all, the carbon dioxide concentration can be read immediately from the height of the peak before recording.
本考案の装置は、以上の通り炭酸ガス吸収管９
による生体ガス試料中の炭酸ガス吸収前後の熱伝
導度差により、きわめて正確に、かつ自己積分方
式として読取り容易な測定を可能にしたものであ
り、臨床検査室や体育検査室における呼気中炭酸
ガス濃度の測定に最適であり、さらには血中ガス
分析にも適用可能である。 As described above, the device of the present invention has a carbon dioxide absorption tube 9
The difference in thermal conductivity before and after absorption of carbon dioxide in a biological gas sample enables very accurate and easy-to-read measurement using a self-integration method, and it is used to measure carbon dioxide in exhaled breath in clinical laboratories and physical education laboratories. It is ideal for measuring concentration and can also be applied to blood gas analysis.
図は本考案の実施例を示す流路図である。
１……試料採取口、２，３，５，６……開閉
弁、４……ポンプ、７……測定及び排出流路、８
……水吸収管、９……炭酸ガス吸収管、１０……
遅延コイル、１１，１２……熱伝導度セル、１３
……記録計、１４……ピストン、１５……ピスト
ン駆動機構、１６……タイマー。
The figure is a flow path diagram showing an embodiment of the present invention. 1...Sample collection port, 2, 3, 5, 6...Opening/closing valve, 4...Pump, 7...Measurement and discharge channel, 8
...Water absorption tube, 9...Carbon dioxide absorption tube, 10...
Delay coil, 11, 12...Thermal conductivity cell, 13
... Recorder, 14 ... Piston, 15 ... Piston drive mechanism, 16 ... Timer.
Claims (1)
を有する全封型シリンダ及びピストンからな
り、前記シリンダ内を前記ピストンにより対称
的な一対のポンプ室として区分し、前記両端の
吸入口の各々を開閉弁を介して共通の生体ガス
採取口に接続するとともに、前記両端の排出口
の各々を開閉弁を介して共通の測定及び排気流
路に接続し、前記一対のポンプ室が同時に逆位
相関係で生体ガス試料の吸入行程及び排出行程
を実行するようにしたポンプと、 ｂ 前記吸入口の一つを開いて対応するポンプ室
に吸入する生体ガス試料が均一に混合されるだ
けの吸入行程時間及びその直後停止時間を設定
すると共に、前記停止時間終了後、前記対応す
るポンプ室の排出口を開き、その間における排
出行程時間を設定する操作を前記一対のポンプ
室について交互に実行するための、ポンプ及び
開閉弁制御タイマーと、 ｃ 前記排出口に接続された少くとも水吸収管及
びその下流側における炭酸ガス吸収管を含む測
定及び排気流路と、 ｄ 前記炭酸ガス吸収管の入口側及び出口側流路
に挿入された一対のセル室からなり、両者の検
出熱伝導度差により、生体ガス中の炭酸ガス濃
度を検出するための熱伝導度検出器、を備えた
ことを特徴とする生体炭酸ガス測定装置。[Claims for Utility Model Registration] a. Consisting of a completely sealed cylinder and a piston having a biological gas sample inlet and an outlet at each end, the inside of the cylinder is divided by the piston into a pair of symmetrical pump chambers, Each of the inlets at both ends is connected to a common biological gas sampling port via an on-off valve, and each of the outlet ports at both ends is connected to a common measurement and exhaust flow path via an on-off valve, a pump in which the pump chambers simultaneously carry out the suction stroke and discharge stroke of the biological gas sample in an antiphase relationship; b. one of the suction ports is opened so that the biological gas sample is uniformly sucked into the corresponding pump chamber; Set the suction stroke time for just mixing and the stop time immediately after that, and after the end of the stop time, open the discharge port of the corresponding pump chamber, and set the discharge stroke time during that time between the pair of pump chambers. c) a measurement and exhaust flow path including at least a water absorption pipe connected to the discharge port and a carbon dioxide absorption pipe downstream thereof; and d) a pump and an on-off valve control timer for alternately executing the carbon dioxide. Thermal conductivity detector consists of a pair of cell chambers inserted into the inlet and outlet flow paths of the gas absorption tube, and detects the carbon dioxide concentration in biological gas by detecting the difference in thermal conductivity between the two. A biological carbon dioxide measuring device characterized by comprising:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11092785U JPS6142444U (en) | 1985-07-18 | 1985-07-18 | Biological carbon dioxide measuring device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11092785U JPS6142444U (en) | 1985-07-18 | 1985-07-18 | Biological carbon dioxide measuring device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6142444U JPS6142444U (en) | 1986-03-19 |
| JPH0114906Y2 true JPH0114906Y2 (en) | 1989-05-02 |
Family
ID=30670045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11092785U Granted JPS6142444U (en) | 1985-07-18 | 1985-07-18 | Biological carbon dioxide measuring device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6142444U (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007003388A (en) * | 2005-06-24 | 2007-01-11 | Taisei Lamick Co Ltd | Method and device for detecting properties of liquid to be inspected |
-
1985
- 1985-07-18 JP JP11092785U patent/JPS6142444U/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6142444U (en) | 1986-03-19 |
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