JPH0136894B2 - - Google Patents

Description

[Detailed Description of the Invention] At the manufacturing stage of medicines, cosmetics, or foods,
For example, during the progress of a reaction such as a physical or chemical change in the treatment tank, it is necessary to frequently sample the contents of the tank. In this case, the necessary conditions for sample collection are that it does not affect the reaction, there is no risk of contamination with foreign substances, and that an appropriate amount of sample can be collected in a short period of time. There is no other way than to pump up the contents of the tank, and therefore, if vacuum treatment is used, it would be impossible to collect the sample, and the conditions required for the collection would not be met.

In view of the above, an object of the present invention is to collect an appropriate amount of sample under optimal conditions from inside a reaction treatment tank or other container with fluid contents as described above. A sample extraction port is provided that allows the mouth of the capsule to be airtightly attached and removed.
When the piston inscribed in the cylinder moves forward and the communication port between the container and the cylinder is closed at the tip of the piston, the sample extraction port can be communicated with the vacuum source through the air passage formed in the piston, and when the piston moves back, The present invention is characterized in that when the communication port between the container and the cylinder is opened, the sample take-out port is isolated from the vacuum source and the sample take-out port is communicated with the inside of the container via the communication port.

Embodiments of the invention will now be described with reference to the accompanying drawings.

In the drawing, 1 is a container containing a reaction treatment tank and other fluid contents, and 2 is a cylinder that is integrally installed with the communication port 3 at the tip communicating with the inside of the container 1; The top surface is a conical shape,
A sample extraction port 5 for attaching and detaching the mouth portion of the sample collection capsule 4 and a connection port 6 to a vacuum source (not shown) were opened in the side wall. An elastic ring 7 was attached to the inner periphery of the sample take-out port 5 to airtightly fit and support the mouth of the capsule 4.

A piston 8 is inscribed in the cylinder 2 and is reciprocated back and forth by a fluid cylinder mechanism or other appropriate device, and its tip has a shape that matches the conical shape of the tip of the cylinder inner cavity, and the cylindrical portion of the piston 8 has an elastic ring 9 spaced apart in the front-rear direction;
9 was fitted so as to be in airtight contact with the inner wall of the cylinder, and a ventilation passage 10 was formed in the space between the two rings 9 by a small diameter portion surrounding the cylindrical body of the piston 8.

In the figure, reference numeral 11 indicates a connecting lever connected to the piston 8 for forward and backward reciprocating motion.

In the illustrated example, the capsule 4 has a relatively small sample intake port at the top to prevent the internal sample from escaping during handling, and for this reason, the bottom can be opened and closed to allow the internal sample to be taken out. show something

Furthermore, the ventilation passage 10 of the piston 8 may be formed by a through hole 10' passing through the cylinder, for example, as shown by the chain line in the drawing, instead of by a small diameter part surrounding the cylinder; in this case, the rotation of the piston 8 need to be prevented.

As shown in FIG. 1, after the mouth of the capsule 4 is fitted into the sample take-out port 5 and held airtight, the piston 8 is advanced to close the communication port 3 with the container 1 with its tip. When doing so, the sample extraction port 5 and the connection port 6 communicate with each other via the ventilation path 10, so that the inside of the capsule 4 can be communicated with the vacuum source.
Therefore, the inside of the capsule 4 is made to have a negative pressure, and at this time, the elastic rings 7, 9, and 9 prevent outside air from entering at all.

Next, as shown in FIG. 2, if the piston 8 is retracted to open the communication port 3 between the container 1 and the cylinder 2, the communication between the sample extraction port 5 and the connection port 6 will be cut off due to the retraction of the ventilation path 10. At the same time, the sample take-out port 5 communicates with the inside of the container 1 through the communication port 3, and the fluid contents in the container 1 are sucked and contained in the capsule 4 as a sample due to the negative pressure state in the capsule 4. When the internal pressures of the capsule 4 and the container 1 are balanced, the suction action stops and an appropriate amount of sample a is stored in the capsule 4, so the piston 8 is restarted with the communication with the vacuum source interrupted. When moving forward, the excess contents in the cylinder 2 are pushed back into the container 1 and the communication port 3 is closed. In this case, since the tip of the inner cavity of the cylinder 2 and the tip of the piston 8 are shaped conically to fit each other, the action of pushing back the excess contents is carried out extremely smoothly. Thus piston 8
After closing the communication port 3 by moving forward, the capsule 4 containing the sample a can be removed from the take-out port 5, and the vacuum action is interrupted during this time.

When further collecting sample a, use another capsule 4.
After binding the sample a to the sample take-out port 5 and creating a negative pressure inside the capsule 4 by vacuum action, the sample a can be sucked into the capsule 4 as described above by retracting the piston 8. Sample a can be collected by repeating the lever action.

In this way, according to the present invention, a sample collection capsule is tied to a cylinder that communicates with the inside of a container in which a sample needs to be collected, the piston in the cylinder is moved forward to create negative pressure in the capsule, and then By retracting the piston, the contents inside the container are suctioned and sampled by the negative pressure inside the capsule, and since the sample collection is carried out within the closed area of the cylinder without contact with the outside air, there is no effect on the reaction of the contents. It has the advantage that it does not cause any foreign matter to enter, is suitable as a means for batch-type sampling of samples, can be sampled in a short time, and is extremely easy to operate.

[Brief explanation of drawings]

The drawings show an embodiment of the present invention; FIG. 1 is a cutaway side view before sample collection, and FIG. 2 is a cutaway side view during sample collection. 1... Container, 2... Cylinder, 3... Communication port, 4...
Capsule, 5... Sample extraction port, 8... Piston, 1
0... Ventilation path.

Claims (1)

[Claims] 1. A sample extraction port was provided in a cylinder communicating with the inside of the container, allowing the opening of the sample collection capsule to be attached and removed in an airtight manner, and the communication port between the container and the cylinder was closed by the forward movement of a piston inscribed in the cylinder. When the sample retrieval port is connected to a vacuum source through a vent passage formed in the piston, and when the piston retreats to open the communication port between the container and the cylinder, the sample retrieval port is isolated from the vacuum source and the sample retrieval port is removed from the vacuum source. 1. A fluid sample collection device, characterized in that the opening is communicated with the inside of the container via a communication port.