JPH01501339A - 改良された核酸ハイブリダイゼーション方法及びそれに用いるキット - Google Patents
改良された核酸ハイブリダイゼーション方法及びそれに用いるキットInfo
- Publication number
- JPH01501339A JPH01501339A JP62506425A JP50642587A JPH01501339A JP H01501339 A JPH01501339 A JP H01501339A JP 62506425 A JP62506425 A JP 62506425A JP 50642587 A JP50642587 A JP 50642587A JP H01501339 A JPH01501339 A JP H01501339A
- Authority
- JP
- Japan
- Prior art keywords
- probe
- probes
- binding
- polynucleotide
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91920186A | 1986-10-14 | 1986-10-14 | |
| US919,201 | 1986-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH01501339A true JPH01501339A (ja) | 1989-05-11 |
Family
ID=25441695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62506425A Pending JPH01501339A (ja) | 1986-10-14 | 1987-10-06 | 改良された核酸ハイブリダイゼーション方法及びそれに用いるキット |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPH01501339A (fr) |
| AU (1) | AU8103687A (fr) |
| CA (1) | CA1309932C (fr) |
| DK (1) | DK324088D0 (fr) |
| FI (1) | FI882800A0 (fr) |
| NO (1) | NO882593D0 (fr) |
| WO (1) | WO1988002785A2 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU593151B2 (en) * | 1986-11-12 | 1990-02-01 | Molecular Diagnostics, Inc. | Method for the detection of nucleic acid hybrids |
| DE3888653T2 (de) * | 1987-12-21 | 1994-07-07 | Applied Biosystems | Verfahren und Testsatz zum Nachweis einer Nukleinsäure-Sequenz. |
| US5354657A (en) * | 1988-01-12 | 1994-10-11 | Boehringer Mannheim Gmbh | Process for the highly specific detection of nucleic acids in solid |
| JP2897959B2 (ja) * | 1988-05-20 | 1999-05-31 | エフ．ホフマン―ラ ロシュ アクチェンゲゼルシャフト | 固定化された配列特異的プローブ |
| GB2225112A (en) * | 1988-11-22 | 1990-05-23 | Ici Plc | Hybridisation probes |
| KR100446358B1 (ko) | 2000-03-31 | 2004-09-01 | 산코 준야쿠 가부시키가이샤 | 프로우브 중합체 제작용 프로우브, 프로우브 중합체의 제작방법 및 그 이용 |
| US20050075309A1 (en) | 2003-07-25 | 2005-04-07 | Richard Storer | Purine nucleoside analogues for treating Flaviviridae including hepatitis C |
| WO2005071401A2 (fr) * | 2004-01-15 | 2005-08-04 | Chiron Corporation | Dosage multiplex homogene pour des cibles d'acides nucleiques |
| EP2743682B1 (fr) | 2011-08-11 | 2017-05-31 | Olympus Corporation | Procédé de détection de particules cibles |
| JP6010034B2 (ja) | 2011-08-30 | 2016-10-19 | オリンパス株式会社 | 標的粒子の検出方法 |
| CN104115003B (zh) | 2012-02-22 | 2016-03-23 | 奥林巴斯株式会社 | 目标粒子的检测方法 |
| JP6095645B2 (ja) | 2012-03-21 | 2017-03-15 | オリンパス株式会社 | 標的核酸分子の検出方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2057685B (en) * | 1979-03-19 | 1983-12-21 | Int Diagnostic Tech | Double tagged immunoassay |
| US4487830A (en) * | 1982-05-14 | 1984-12-11 | American Hoechst Corporation | Enzyme/immunofluorescent assay for autoantibodies |
| CA1222680A (fr) * | 1983-07-05 | 1987-06-09 | Nanibhushan Dattagupta | Dosages de sequences de nucleotides particulieres dans des echantillons d'adn |
| NO843838L (no) * | 1983-09-26 | 1985-03-27 | Ortho Diagnostic Systems Inc | Fremgangsmaate for detektering av nukleinsyre |
| CA1260372A (fr) * | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Methode d'hybridation pour la detection de materiaux genetiques |
| US4820630A (en) * | 1984-11-23 | 1989-04-11 | Digene Diagnostics, Incorporated | Assay for nucleic acid sequences, particularly genetic lesions, using interactive labels |
| GB8432118D0 (en) * | 1984-12-19 | 1985-01-30 | Malcolm A D B | Sandwich hybridisation technique |
| CA1272443A (fr) * | 1985-02-22 | 1990-08-07 | Nanibhushan Dattagupta | Essai de double hybridation en solution-phase pour deceler des sequences polynucleotidiques |
| GB8508431D0 (en) * | 1985-04-01 | 1985-05-09 | English Clays Lovering Pochin | Paper coating apparatus |
| GB8509367D0 (en) * | 1985-04-12 | 1985-05-15 | Amersham Int Plc | Nucleic acid hybridisation |
| IL79112A (en) * | 1985-06-13 | 1992-01-15 | Abbott Lab | Method for the isolation of a nucleic acid sequence and kit for performing a hybridization assay |
| EP0238332A2 (fr) * | 1986-03-19 | 1987-09-23 | Cetus Corporation | Méthode d'hybridation en phase liquide et trousse de réactifs pour détecter la présence de séquences d'acides nucléiques dans des échantillons |
| GB8607101D0 (en) * | 1986-03-21 | 1986-04-30 | Serono Diagnostics Ltd | Immunoassay |
-
1987
- 1987-10-06 JP JP62506425A patent/JPH01501339A/ja active Pending
- 1987-10-06 WO PCT/US1987/002548 patent/WO1988002785A2/fr not_active Ceased
- 1987-10-06 FI FI882800A patent/FI882800A0/fi not_active Application Discontinuation
- 1987-10-06 AU AU81036/87A patent/AU8103687A/en not_active Abandoned
- 1987-10-07 CA CA000548798A patent/CA1309932C/fr not_active Expired - Lifetime
-
1988
- 1988-06-13 NO NO882593A patent/NO882593D0/no unknown
- 1988-06-14 DK DK324088A patent/DK324088D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1988002785A3 (fr) | 1988-07-14 |
| FI882800A7 (fi) | 1988-06-13 |
| AU8103687A (en) | 1988-05-06 |
| FI882800L (fi) | 1988-06-13 |
| NO882593L (no) | 1988-06-13 |
| FI882800A0 (fi) | 1988-06-13 |
| NO882593D0 (no) | 1988-06-13 |
| WO1988002785A2 (fr) | 1988-04-21 |
| DK324088D0 (da) | 1988-06-14 |
| CA1309932C (fr) | 1992-11-10 |
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