JPH02223578A - チオケテン誘導体及びその製造方法 - Google Patents

チオケテン誘導体及びその製造方法

Info

Publication number
JPH02223578A
JPH02223578A JP1276162A JP27616289A JPH02223578A JP H02223578 A JPH02223578 A JP H02223578A JP 1276162 A JP1276162 A JP 1276162A JP 27616289 A JP27616289 A JP 27616289A JP H02223578 A JPH02223578 A JP H02223578A
Authority
JP
Japan
Prior art keywords
general formula
thiazolyl
formula
phenyl
ylidene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1276162A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0587069B2 (2
Inventor
Choong Sup Kim
チョング　スプ　キム
Jeong Seok Chae
ジェオング　セオク　チャエ
Ho Seong Yoo
ホ　セオング　ヨー
Jong Wook Lee
ジョング　ウーク　リー
Jae Gil Park
ジャエ　ジル　パーク
Jeong-Won Lee
ジェオング　ウォン　リー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yuhan Corp
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of JPH02223578A publication Critical patent/JPH02223578A/ja
Publication of JPH0587069B2 publication Critical patent/JPH0587069B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/04—Four-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
JP1276162A 1988-10-27 1989-10-25 チオケテン誘導体及びその製造方法 Granted JPH02223578A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019880014023A KR920005434B1 (ko) 1988-10-27 1988-10-27 티오케텐 유도체와 그의 제조방법
KR1988-14023 1988-10-27

Publications (2)

Publication Number Publication Date
JPH02223578A true JPH02223578A (ja) 1990-09-05
JPH0587069B2 JPH0587069B2 (2) 1993-12-15

Family

ID=19278798

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1276162A Granted JPH02223578A (ja) 1988-10-27 1989-10-25 チオケテン誘導体及びその製造方法

Country Status (6)

Country Link
US (1) US5103013A (2)
EP (1) EP0366614B1 (2)
JP (1) JPH02223578A (2)
KR (1) KR920005434B1 (2)
DE (1) DE68908838T2 (2)
HK (1) HK37795A (2)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922757A (en) * 1996-09-30 1999-07-13 The Regents Of The University Of California Treatment and prevention of hepatic disorders
US6218437B1 (en) 1996-09-30 2001-04-17 The Regents Of The University Of California Treatment and prevention of hepatic disorders
CN113105424B (zh) * 2021-03-25 2022-06-07 华中农业大学 基于黄单胞菌外源代谢物的杀菌化合物及制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5511906B2 (2) * 1972-08-23 1980-03-28
JPS5028498B2 (2) * 1973-02-03 1975-09-16
JPS50100062A (2) * 1973-04-06 1975-08-08
JPS5215389B2 (2) * 1973-08-15 1977-04-28
US4022907A (en) * 1975-06-06 1977-05-10 Nihon Nohyaku Co. Ltd. Pharmaceutical compositions containing 1,3-dithiacycloalkylidene malonates
JPS5927887A (ja) * 1982-08-09 1984-02-14 Nippon Nohyaku Co Ltd ジチオラン誘導体及び肝臓疾患治療剤
US4663319A (en) * 1984-01-14 1987-05-05 Tanabe Seiysku Co., Ltd. 3-(1,3-dithiol-2-ylidene)-2,4-dioxopyrrolidines, -piperidines, and -hexahydroazepines and use thereof against hepatic diseases
JPS62158274A (ja) * 1985-12-28 1987-07-14 Banyu Pharmaceut Co Ltd 置換−１，３−ジチエタン誘導体
JPS632988A (ja) * 1986-03-19 1988-01-07 Hokko Chem Ind Co Ltd １，３−ジチオ−ル−２−イリデン　スルホニル酢酸誘導体
KR910005895B1 (ko) * 1987-07-01 1991-08-06 주식회사 유한양행 1,3-디티올-2-일리덴 유도체와 그의 제조방법

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J.PRAKT.CHEM=1981 *

Also Published As

Publication number Publication date
KR900006313A (ko) 1990-05-07
EP0366614B1 (en) 1993-09-01
JPH0587069B2 (2) 1993-12-15
US5103013A (en) 1992-04-07
KR920005434B1 (ko) 1992-07-03
DE68908838D1 (de) 1993-10-07
HK37795A (en) 1995-03-24
EP0366614A2 (en) 1990-05-02
DE68908838T2 (de) 1994-02-03
EP0366614A3 (en) 1990-06-27

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees