JPH0239268B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a skin fitting that exhibits an effective anti-inflammatory effect on diseases such as shoulder stiffness and lower back pain through the interaction of mineral ions and magnetic lines of force.

Living organisms such as the human body contain cell constituent elements at predetermined concentration ratios when in a normal physiological state. for example,
The sodium and potassium ion concentration ratios [Na ⁺ ]/[K ⁺ ] are maintained at different constant values inside and outside the animal cell membrane, and as the sodium ion concentration in the cell increases, blood pressure increases, and conversely, the intracellular potassium ion concentration increases. It has the property that as the ion concentration increases, blood pressure decreases. The concentration of these essential living elements is regulated by the organic functioning of the organs of the living body.
If organ dysfunction occurs for some reason,
Connection with other organs is inhibited, resulting in an abnormal ion concentration ratio. In other words, an abnormality occurs in the energy consumption process for maintaining the activities of the living body (metabolic abnormality), making it impossible for the living body to perform its original functions.
Surgical repair is required when organ dysfunction is caused by physical damage such as trauma, but it can also be caused by external factors such as bacterial invasion or internal factors such as cancerous tumors. In the case of such "diseases", it is extremely important to increase the autoimmunity of the body in parallel with the administration of anti-inflammatory drugs. If the body's self-defense function is activated and the abnormality can be repaired by itself, this would be an ideal treatment method. Recently, interferon and interleukin have been attracting attention in animals as substances that control autoimmunity. Experiments are being conducted to synthesize and administer large quantities of these substances using genetic recombination technology. However, it has been reported that when synthetic interferon is administered to the human body, there are problems such as compatibility and that it is not as effective as originally expected. Therefore, interferon inducers, which induce interferon in vivo, have suddenly attracted attention in relation to autoimmune diseases. Among several interferon inducers, semiconductors such as germanium and silicon are known to be simple and effective. Normally, these elements are organicized and administered to living organisms, where they are absorbed into cellular tissues and exert their effects. However, the present inventors have applied a kind of biological battery phenomenon to the discovery that ionized mineral elements can quickly penetrate into living cells from the skin surface as cations and exert their effects, and have filed an application.

The purpose of the present invention is to further enhance the therapeutic effect on living organisms by causing these mineral ions released into living bodies to drift more quickly and forcibly.

In order to achieve the above object, the present invention uses a permeation element which is formed by electrically joining two types of conductive minerals with different standard monopolar potentials, and the direction of movement of the permeated ions generated and released from the element is influenced. In a device consisting of a permanent magnet capable of applying a strong magnetic field and a skin contact means attached to the element, the mineral having a lower standard unipolar potential among the above-mentioned conductive minerals is a single crystal or has a particle size of 100 μm or more. Disclosed is a skin joint which is a semiconductor made of polycrystalline material. If the semiconductor is a single crystal or a polycrystal with a grain size of about 100 μm or more,
This is because it is necessary for efficient ion generation that the interfacial distance between the crystals be sufficiently longer than the extension length of the majority carriers in the semiconductor.

In the previous application "Mineral Ion Penetrator" by the present inventor, a metal with a higher standard unipolar potential and a semiconductor crystal with a lower standard unipolar potential are electrically joined,
The metal and semiconductor crystal are simultaneously attached to the skin surface of the living body using a skin contacting means such as an adhesive tape. As a result, a battery action is induced between the two types of conductive mineral electrodes and the living body, and the positive potential effect of the metal anode causes the metal-
The Schottky barrier at the interface of the semiconductor crystal is biased, and free electrons flow into the metal side through the semiconductor crystal. In order to satisfy the condition of charge neutrality, free semiconductor ions penetrate into the living body at the interface between the semiconductor crystal and the skin of the living body. In the "mineral ion permeator" that utilizes this kind of metal-semiconductor bonding,
The Schottky barrier formed at the interface between the semiconductor crystal and the biological skin surface prevents the injection of electrons from the biological skin surface into the semiconductor crystal, so unlike the case of bonding between dissimilar metals, a loop-shaped electronic current circuit is Instead, the free electrons that flow out to the metal side due to ionization of the semiconductor crystal are replenished. Therefore, while a junction made of dissimilar metals is suitable as a current source, a junction of a metal and a semiconductor has the advantage that it is easy to obtain ions by ionization and is suitable as an ion source.

The present invention stands as an improvement to such mineral ion permeators. In the prior application, semiconductor ions perform ion exchange in a natural manner due to the properties of living organisms and the two conductive minerals themselves.

The present invention allows ions to be exchanged with a wider range of living organisms. For this purpose, a forced force was applied to the ions from the outside. Force applied from the outside is applied by a magnetic field. That is, when ions are moved in a magnetic field, the ions receive a force in a predetermined direction due to Fleming's left-hand rule. This causes the ions to diffuse into a wide area. As described above, the present invention utilizes the metal-semiconductor junction to effectively allow semiconductor ions generated from the cathode to penetrate into the body. Therefore, for example, Japanese Patent Application Laid-open No. 1983-
Treatment devices that are simply a combination of a semiconductor and a magnet as disclosed in No. 58170, or a combination of a metal and a magnet as disclosed in Japanese Patent Application Laid-Open No. 188465/1988, have no effect on the electron flow due to magnetic lines of force. Even if it is, it is completely unrelated to the present invention as long as it does not have any medicinal effects due to iontophoresis.

The present invention will be explained in more detail.

The present invention utilizes the well-known interaction of charged particles moving in a magnetic field, and its principle is as shown in FIG. In other words, for example, if a static magnetic field with a magnetic flux density B is applied vertically from the front to the back of the paper within the human skin, cations (point charges) penetrating deeper from the skin surface at a velocity v. q) receives force F in the direction shown in the figure and draws a circular orbit with radius r. Its radius r is the mass of the cation m
Then, it is expressed as r=mv/qB (1), and is usually about several to tens of micrometers.
In reality, there is a velocity component that is not perpendicular to the magnetic field, so
Cations diffuse into the tissues deep within the skin in a spiral motion. Due to the forced movement of semiconductor cations by such a magnetic field, tissues in the movement path are stimulated in a region having a width of 10 ³ -10 ⁵ times the cation diameter. This is simply a therapeutic effect (nervous stimulation effect, fever effect) caused by physical collision.
It also means that physiological effects (for example, interferon-inducing effects) are exerted in a wide range of tissues due to the penetration of pharmacologically effective cations.

Furthermore, in the skin fitting of the present invention, cations are released from the cathode side, and at the same time, a reduction reaction of iron and copper ions contained in the body occurs in the body under the anode.
There is an advantage in that the fear that reduced ions will accumulate in the body under the anode after a certain period of time, that is, the so-called polarization effect, will be eliminated by the forced diffusion effect of the magnetic field.

In addition, in the case of local simple metabolic disorders such as stiffness or muscle pain, magnetic lines of force act on capillaries with stagnation of blood flow, forcing ions in the blood vessels to move, promoting blood circulation and vascular blood vessels. It has the advantage that the mineral cations that have penetrated into the body are quickly transported to the affected area, promoting metabolism and quickly producing a curative effect.

Hereinafter, the present invention will be described in detail based on examples.

Embodiment 1 As shown in FIG. 2, the skin fitting includes one ring-shaped permanent magnet 3, a metal germanium (Ge) polycrystal 1 inscribed inside the ring of the permanent magnet 3, and the permanent magnet 3. Pt plating layer 2 provided on the N-pole surface,
and an adhesive bandage 4. The metal Ge polycrystal 1 has a structure that protrudes in the direction of the contact skin surface. The metal Ge polycrystal 1 and the Pt plating layer 2 form minerals with different standard unipolar potentials. Metal Ge single crystal 1
The standard unipolar potential of is smaller than the standard unipolar potential of the Pt layer 2. Note that the metal Ge referred to here is a common name from a metallurgical perspective, meaning that it is not a Ge compound but a single element with a so-called metallic luster, and from an electronics perspective, it is a semiconductor. This is a well-known fact. metal
Ge polycrystalline 1 and Pt layer 2 are electrically connected (junction)
I'm letting you do it. For example, the permanent magnet 3 is a type of conductor, and is used as a guide path.
For this purpose, the Ge polycrystal 1 and the permanent magnet 3 were short-circuited at a predetermined location. This short-circuit point may be the S pole surface and the surface of the metal Se polycrystal 1, or may be the ring inscribed surface of the permanent magnet 3.

With this configuration, since the metal Ge polycrystal 1 and the Pt layer 2 have different standard monopolar potentials, an ion exchange effect is performed between them and the inside of the skin surface 5. However, the magnetic flux produced by the permanent magnet 3 acts on these ions, and a force F is applied in the direction shown in the figure, causing the ions to diffuse over a wide range.

This skin contact tool was actually applied to the affected skin surface 5 of a patient complaining of shoulder stiffness and lower back pain, and the therapeutic effect was investigated. Ge polycrystalline 1 is a polycrystalline pellet with a purity of 4N and an average grain size of 500μm, with a diameter of 6mm.
The height is 1.5 mm, and the ring magnet 3 circumscribing this is made of ferrite with an inner diameter of 6 mm, an outer diameter of 9 mm, a height of 1.5 mm, and a residual magnetic flux density of 800 Gauss. This N-pole surface is plated with Pt2 with a thickness of approximately 10 μm.
Further, the magnet 3 and the Ge polycrystal 1 are short-circuited by silver paste on the adhesive surface of the bandage 4. This skin joint was applied to the affected areas of 50 men and women aged 32 to 74 years who complained of stiff shoulders and 50 men and women aged 40 to 81 years of age who complained of lower back pain, and the cases were observed 48 hours later. As a result, 88% of patients with shoulder stiffness were almost completely cured or their pain was significantly reduced, regardless of gender or age, and 76% of patients with low back pain were completely cured or their pain was significantly reduced.
% of patients observed significant improvement in symptoms. On the other hand, for comparison, 60 patients with stiff shoulders were divided into two groups.
In one set, only the combination of Ge polycrystal 1 and bandage 4 shown in Fig. 2 was applied to the affected area, and in the other set, only the magnetic therapy device with a residual magnetic flux density of 800 Gauss was applied to the affected area. The cure results were observed after 48 hours, respectively.
As a result, in the group to which only Ge1 was applied, 20% showed significant improvement in pain, while 53% showed no improvement at all. Furthermore, in the group where only the magnetic therapy device was applied, 33% showed significant pain improvement, and 30% showed no improvement at all. These clinical data support the excellent properties of the mineral ion magnetic therapy device of the present invention. This is due to the biological battery action (in the skin under the Pt anode, Fe ³⁺ → Fe ²⁺ is reduced and Ge
Ge ²⁺ ions are released into the skin from the cathode), and the Ge ions that have penetrated into the skin
As explained with reference to FIG. 1, this effect is presumed to be caused by forced movement by a magnetic field (force F acting in the direction shown in FIG. 2).

Example 2 As shown in Fig. 3, a Cu magnet was circumscribed around a cylindrical bar magnet 3 (residual magnetic flux density 1200 Gauss) with a diameter of 3 mm and a length of 3 mm, and the outside was plated with silver 2 with a thickness of about 10 μm. ₂ Ring of Se single crystal 1 (inner diameter 3 mm, outer diameter 7
mm, height 3 mm). Cu ₂ Se is an n-type semiconductor, and the bar magnet 3 and the Cu ₂ S _u single crystal 1 are electrically short-circuited by low-temperature soldering at their contact surfaces. A skin fitting with a bandage 4 pasted on the S-pole side of the bar magnet 3 as shown in the figure was applied to a patient with chronic arthritis to examine its effectiveness.

The above skin adhesive was applied to the affected areas of 5 female patients who had inflammation in the knee joints of both legs or one leg and complained of severe swelling and pain, and after 5 days, the application position was updated little by little every 24 hours. When examining the condition of the patients, swelling and pain were significantly reduced in 4 patients, and a remarkable curing effect was observed. Improvement in pain was also observed in the remaining patient. Since several days to several weeks have passed since the onset of the disease in these patients, the above-mentioned curing effect is clearly considered to be caused by the skin fitting of the present invention. The medicinal effect is due to the Cu ₂ Se ions released into the skin from the Cu ₂ Se-Ag ion permeator (further converted into Cu ions in the body).
) is thought to be separated into Se ions, but the bar magnet 3
This is thought to have occurred as a result of the spiral movement being influenced by the magnetic field created by the patient, which heightened the patient's autoimmunity.

Example 3 Grain boundary size of approximately 5 mm square on the adhesive surface of bandage 4
mm n-type semiconductor SiC polycrystalline 1 and a 2 x 5 mm Au plate 2 are juxtaposed and fixed at an interval of about 2 mm, and lead wires 7 are connected to both conductive minerals 1 and 2 respectively to join them. Super power placed on the adhesive surface of Bandage 4
I connected it to a 3V mercury battery 6 so that SiC1 was positive and Au2 was negative. Further, a "U"-shaped magnet 3 was placed so as to straddle the SiC 1 in a direction perpendicular to the line of juxtaposition of the conductive minerals 1 and 2. The gap distance between the N and S poles of the magnet 3 is 1 cm.
Therefore, as shown in Figure 4, magnet 3 and
Not in direct contact with SiC1. The residual magnetic flux density of this magnet 3 is 1500 Gauss. A skin fitting having the structure shown in Fig. 4 was applied to a patient suffering from neurogenic gastritis to examine its effectiveness. That is, this skin contact tool was applied to the skin surface 5 of the affected area complaining of pain using finger pressure, and care was taken so that the N and S poles of the conductive minerals 1 and 2 and the magnet 3 came into contact with the skin surface at the same time. When applied to five male and female patients between the ages of 32 and 45, the mercury battery 6 anode -SiC1-human body-Au2-
It was confirmed that a direct current of 0.1 to 2 mA was flowing in the closed circuit of the six cathodes of the mercury battery. When checked for symptoms approximately 24 hours later, all patients reported pain relief. In particular, it was found that the symptoms of gastritis had completely disappeared from two of the patients. This is presumed to be the result of the SiC ions being biased by the mercury battery 6 and penetrating into the skin, penetrating deep into the skin while making a spiral motion within the magnetic field, and increasing the medicinal effect.

As described in detail in the embodiments above, the skin fitting of the present invention is capable of absorbing semiconductor cations from outside the body, which have a positive effect on living bodies, and the subsequent helical movement of ions due to interaction with magnetic lines of force. It was confirmed that it can have an effective anti-inflammatory effect on the affected areas.

In the above embodiments, the anti-inflammatory effect of the skin fitting of the present invention was mainly discussed, but other elements necessary for the human body, such as calcium, magnesium,
It is obvious that supplementation of iron, copper, etc. can also be carried out from outside the body according to the present invention.

[Brief explanation of drawings]

FIG. 1 is a diagram for explaining the principle of the present invention, and FIGS. 2 to 4 each show a structural outline of a skin fitting used in different embodiments. In the figure, 1... conductive mineral with lower standard unipolar potential (semiconductor crystal), 2... higher conductive mineral (metal), 3... permanent magnet, 4... skin contact means, 5... skin surface, 6... bias DC power supply, 7...Lead wire.

Claims (1)

[Claims] 1. A mineral iontophoresis element formed by electrically bonding two types of conductive minerals with different standard unipolar potentials;
A device comprising a permanent magnet capable of applying a strong magnetic field that influences the direction of motion of penetrating ions generated and released from the element, and skin contact means affixed to the element. A leather fitting characterized in that the mineral with a lower polar potential is a semiconductor consisting of a single crystal or a polycrystal with a grain size of 100 μm or more. 2. The mineral iontophoretic device according to claim 1, wherein the two types of conductive minerals are one type selected from the group consisting of elements, alloys, and compounds. 3. In the mineral iontophoretic device according to claim 1, between the two types of conductive minerals, the conductive mineral with a lower standard unipolar potential is directly the conductive mineral with a higher standard unipolar potential. A skin contact that connects a DC power source in a direction that biases it negatively. 4. Mineral ions, such that a part of the magnetic circuit of the permanent magnet according to claim 1 is composed of at least one of the two types of conductive minerals constituting the mineral iontophoresis element. A skin fitting with a structure in which the permeation element and the permanent magnet are in close contact with each other.