JPH03123714A - Acricide for interior of house - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to an indoor acaricide characterized by containing cinnamon oil as an active ingredient.

[Conventional technology]

An extremely wide variety of mite species inhabit the earth, and for example, the citrus spider mite, the two-spotted spider mite, and the neck mite, which parasitize plants, cause great damage to agricultural crops.

Acaricides for agricultural use have been under development for a long time, and new promising compounds have recently been discovered one after another.

On the other hand, due to changes in the living environment in recent years, dust mites, dust mites, etc. have been occurring in homes, causing not only discomfort but also problems such as allergic asthma and skin rashes. It has been known that organic phosphorus agents such as Sumithion and Diazinon are effective against these indoor mites, but there are obstacles to practical application due to safety and resistance issues for humans and livestock, and accurate extermination is difficult. There was a great need to establish a method.

Recently, the application of highly safe pyrethroid agents and acaricides using terpene compounds have been published in Japanese Patent Application Laid-Open No. 63-10490.
Although it is disclosed in Publication No. 5 and Japanese Unexamined Patent Publication No. 1-163104, the extermination effect is not necessarily satisfactory, and attempts to use tick repellents instead of acaricides have also been made because of the habitat. The current situation is that the development of accurate acaricides is desperately needed, as simply moving them is not a fundamental extermination method.

[Problem that the invention seeks to solve]

The present invention solves the drawbacks of conventional indoor acaricides, such as toxicity to humans and livestock, and insufficient extermination efficacy, and is superior in safety and effectiveness, as well as being inexpensive and easy to use. The present invention provides a miticide for use in the United States.

(Means for solving the problem) In order to achieve the above object, the present inventors investigated the acaricidal effect of natural essential oils that are considered to be highly safe, and discovered that cinnamon oil has a particularly strong effect of killing indoor dust mites. recognize that it has
Cinnamon oil used in the present invention is a highly safe natural product that is widely used as a natural fragrance and is also listed in the pharmacopoeia for medical use. In addition, it was already known that cinnamon powder or water or alcohol extracts of cinnamon have the effect of exterminating agricultural pests (Japanese Patent Application Laid-open No. 1-132505), but cinnamon oil has a lethal effect on indoor dust mites. Something was unknown.

Although it is possible to apply the active ingredient to the indoor acaricide of the present invention as it is, it is usually preferably applied in various forms, such as emulsions, hydrates, etc., depending on the purpose of use, using suitable carriers and other compounding agents. agents, powders, oils, aerosols, liniments,
Used as tablets, etc.

In addition, the above-mentioned active ingredients have higher volatility than conventional acaricides, so they can be used in preparations that can be released at room temperature, or in so-called so-called evaporative products that are heated and evaporated by impregnating them into a suitable holding body, such as a pulp plate, and then using a suitable heating evaporator. It can also be applied as a heating transpiration agent or fumigation agent. Examples of liquid carriers include:
Water, alcohols (methyl alcohol, ethyl alcohol, ethylene glycol, etc.), ketones (acetone,
methyl ethyl ketone, cyclohexanone, etc.), ethers (ethyl ether, dioxane, cellosolves, etc.),
Aliphatic hydrocarbons (gasoline, kerosene, kerosene, etc.),
Aromatic hydrocarbons (benzene, toluene, xylene, methino-naphthalene, etc.),
Dichloromethane, trichlorobenzene, Freon 113,
Solvents such as Freon 114B, etc.), esters, acid amides, and nitriles are suitable, and one or a mixture of two or more of these may be used. In addition, solid carriers include, for example, clays (kaolin, bentonite, etc.),
Talc, silica, calcium carbonate, alumina powder,
Activated carbons, vegetable powders such as wood flour, starch, and wheat flour, cyclodextrins, and the like are suitable, and one or a mixture of two or more of these may be used. In addition, suitable compounding agents include emulsifiers, dispersants, spreading agents, propellants, penetrants, surfactants, stabilizers, film forming agents, and volatility control agents, and one or more of these agents may be used. A mixture of is used.

In addition, examples of coating film forming agents include cellulose derivatives, vinyl resins, alkyd resins, urea resins, silicone resins, urethane resins, and epoxy chestnut resins, and examples of volatilization control agents include tricyclo decan,
Cyclododecane, 2,4,6. −) Liisobrovir −
Sublimable carriers such as 1,3,5,-) dioxane and trimethylene norbornene, higher fatty acid esters such as butyl stearate and isopropyl myristate, bepyronyl butoxide, cinepirin 500, etc. as retention agents. I can give an example.

Furthermore, the indoor acaricide of the present invention may contain various insecticides, synergists, antioxidants, bactericides, fungicides, repellents, fragrances, colorants, etc. Agents include allethrin, d-T80 allethrin, prarethrin, d-
780-Framethrin, d-T2O-phthalthrin, d
-780 resmethrin, phenothrin, permethrin,
Pyrethroid compounds such as cyphenotrin, cypermethrin, fenvalerate, and etofenbrox; organophosphorus compounds such as fenitrothion, diazinon, and pyridafenthione; and NAC, MTMC, and PH.
Examples include carbamate compounds such as C.

In addition, the indoor acaricide of the present invention includes empenthrin and DD.
VP, or a combination of volatile insect repellents such as Baladichlorobenzene, naphthalene, and camphor, DEET, N
A highly effective multi-purpose acaricide can also be obtained by appropriately mixing repellents such as -butylacetanilide and N,N-diethyl succinamate.

The amount of active ingredient in the indoor acaricide of the present invention and its usage amount are appropriately determined depending on the dosage form, application target, application method, application location, etc. For example, to exterminate mites that live on tatami mats, such as mites, 0.1 or more, preferably 1 to 2 mites per tatami mat.
g of the above-mentioned active ingredients, and 0.5 to 2 g per rrr for exterminating the Dermatophagoides mites that live in carpets.
It is desirable to treat the active ingredients of

The present invention also provides a mite-controlling material in which the above-mentioned acaricide is retained in a base material.

The mite-controlling material is used as a film, sheet, cushion, filler for bedding, architecture, and construction material that has mite-controlling properties by utilizing the characteristics of its base material. Examples of the base material here include synthetic resin sheets such as polyethylene, polypropylene, polyester, and ethylene-vinyl acetate, animal and plant materials or inorganic fiber sheets, cushions,
Examples of fillers for bedding include natural cotton, synthetic cotton, feathers, buckwheat, and foamed plastic.

The thus obtained indoor miticide of the present invention or the mite control material containing the same exhibits a high extermination effect against various mites, and is particularly effective against bronchial asthma, atopic dermatitis, nasal allergies, etc. Dermatophagoides mites, such as Dermatophagoides nigra, which are said to cause
It is extremely useful for exterminating mites such as woolly mites, mites, mites, and dust mites, which are thought to be the cause of allergic diseases and human mite diseases. Hereinafter, the present invention will be explained in more detail using test examples and examples, but the present invention is not limited to the following examples unless the gist thereof is exceeded.

Test example 1 The effects of various essential oils on indoor dust mites were investigated.

100μ of Long/d acetone solution of various essential oils on approximately 1cm square cloth! (200 μl in the case of woolly mites) was dropped, air-dried, and used as a sample.

On the other hand, a rectangular filter paper of 5C11 x 10C11 was folded in half, and 50 to 150 Dermatophagoides or Pleurotus mites were released into it, sandwiched between two acrylic cylinders (inner diameter 4.1 CI, height 2 cm), and fixed with a rubber band. ,
1 was placed in a container with a lid (65χRH) so as to cover the essential oil-impregnated sample. 27~28°C1
After standing for 24 hours, the number of molten mites and the number of dead mites were counted, and the lethal efficacy was determined as shown in the following table.

Table 1. Fatal effect of various essential oils on indoor dust mites Katsura
Peel oil Eucalyptus oil Lavender oil Clove oil Bergamot oil Rose oil Lanidel oil too to.

12.0 10.010.0
8.09.5
7.5 5.9 5.0 5.5 5.6 B, 2 6.2 As a result of the test, the cinnamon oil used in the present invention has an extremely high lethal effect of volatile molecules against indoor dust mites, and is suitable for sustained release preparations. It was confirmed that it has excellent applicability to evaporated preparations that do not require heating or heating.

On the other hand, eucalyptus oil, which is said to have repellent and acaricidal effects, had no effect in this experiment.

Test Example 2 Cinnamon oil 10μ/d on 5CIIX10C1 rectangular filter paper
Two drops of 0.5μ of an acetone solution were added, and after air-drying, it was folded in two, and about 100 Dermatophagoides mites were released in between. V: As in Experiment 1, this filter paper was sandwiched between acrylic cylinders and fixed with rubber bands, and then placed in a container with a volume of 12M (27-28°C, 165°C).
XRH) was placed, and after being left for 24 hours, the number of live mites and the number of dead mites were counted, and the acaricidal efficacy of each test compound was examined.

As a control, the pyrethroid compound d-T2O
- A 10 mM acetone solution of resmethrin and citral and carvone disclosed in JP-A-1-163104 was used.

Table 2. Effect of cinnamon oil by filter paper contact method Cinnamon oil 0 96 96 d-T2O-Resume) phosphorus 108
25 133 Citral 422668 L-Carvone 57 18 7500 18.8 38.2 24.0 As a result of the test, the cinnamon oil used in the present invention showed high contact miticidal efficacy against Dermatophagoides nigricans, and compared to the control compound d-
It was very superior to T2O-resmethrin, citral and carvone disclosed in JP-A-1-163104.

Example 1 The above compounds (1), (2), (6), (8),
Oω and 03) l each.

g, add a small amount of fragrance and kerosene to make a total of 120d, and mix this with a mixture of liquefied petroleum gas and dimethyl ether (
After filling a pressure-resistant aerosol can with 1801d (1:1 volume ratio), an injection device was attached to obtain an indoor acaricide of the present invention in the form of an aerosol.

20I per 1M for carpets infested with Dermatophagoides
When we observed the number of mites in the carpet one day after spraying, the ratio of dead mites to the number of collected mites was 90%.
That was it.

Example 2 The compounds Nα (2), (4), (5) and (8)
An indoor acaricide of the present invention in the form of a tablet was prepared by mixing 2 g of each with 8 g of a gelling agent by a conventional method.

When two of the above tablets (wrapped in Japanese paper) were placed and stored in a cloth bag containing a futon, no mites were observed living on the futon.

〔Effect of the invention〕

The indoor acaricide of the present invention contains cinnamon oil as an active ingredient, and therefore has excellent safety and usability, and exhibits high acaricidal efficacy.

Claims (1)

[Claims] An indoor acaricide characterized by containing cinnamon oil as an active ingredient.