JPH0322943B2 - - Google Patents

Info

Publication number: JPH0322943B2
Authority: JP; Japan
Prior art keywords: hole; holes; centrifugation; sample; liquid
Prior art date: 1982-09-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP58160609A

Other languages

English (en)

Japanese (ja)

Other versions

JPS5965747A (ja

Inventor

Eberure Gyunteru

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ANDOREASU HETSUTEITSUHI

Original Assignee

ANDOREASU HETSUTEITSUHI

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-09-02

Filing date

1983-09-02

Publication date

1991-03-27

1983-09-02 Application filed by ANDOREASU HETSUTEITSUHI filed Critical ANDOREASU HETSUTEITSUHI

1984-04-14 Publication of JPS5965747A publication Critical patent/JPS5965747A/ja

1991-03-27 Publication of JPH0322943B2 publication Critical patent/JPH0322943B2/ja

Status Granted legal-status Critical Current

Links

238000000034 method Methods 0.000 claims abstract description 34
210000002919 epithelial cell Anatomy 0.000 claims abstract description 25
238000010186 staining Methods 0.000 claims abstract description 24
238000000926 separation method Methods 0.000 claims abstract description 18
238000005119 centrifugation Methods 0.000 claims description 94
239000007788 liquid Substances 0.000 claims description 90
239000011521 glass Substances 0.000 claims description 64
239000000725 suspension Substances 0.000 claims description 23
230000008878 coupling Effects 0.000 claims description 17
238000010168 coupling process Methods 0.000 claims description 17
238000005859 coupling reaction Methods 0.000 claims description 17
210000004027 cell Anatomy 0.000 claims description 15
230000008859 change Effects 0.000 claims description 4
239000013049 sediment Substances 0.000 claims description 4
238000010030 laminating Methods 0.000 claims 1
230000003287 optical effect Effects 0.000 claims 1
230000008569 process Effects 0.000 abstract description 16
239000012530 fluid Substances 0.000 abstract description 3
239000006285 cell suspension Substances 0.000 abstract description 2
238000011835 investigation Methods 0.000 abstract 1
238000011049 filling Methods 0.000 description 13
239000000463 material Substances 0.000 description 10
238000004043 dyeing Methods 0.000 description 8
238000012360 testing method Methods 0.000 description 8
230000009471 action Effects 0.000 description 7
238000004062 sedimentation Methods 0.000 description 6
239000000243 solution Substances 0.000 description 6
239000011148 porous material Substances 0.000 description 5
210000005056 cell body Anatomy 0.000 description 4
238000009826 distribution Methods 0.000 description 4
238000012545 processing Methods 0.000 description 4
230000007704 transition Effects 0.000 description 4
230000008901 benefit Effects 0.000 description 3
238000011161 development Methods 0.000 description 3
238000010586 diagram Methods 0.000 description 3
238000003860 storage Methods 0.000 description 3
238000011282 treatment Methods 0.000 description 3
229920000742 Cotton Polymers 0.000 description 2
206010028980 Neoplasm Diseases 0.000 description 2
238000000151 deposition Methods 0.000 description 2
238000011156 evaluation Methods 0.000 description 2
238000001746 injection moulding Methods 0.000 description 2
210000000265 leukocyte Anatomy 0.000 description 2
238000011068 loading method Methods 0.000 description 2
230000009467 reduction Effects 0.000 description 2
238000007789 sealing Methods 0.000 description 2
238000007447 staining method Methods 0.000 description 2
239000012192 staining solution Substances 0.000 description 2
229920002994 synthetic fiber Polymers 0.000 description 2
238000005406 washing Methods 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
239000004677 Nylon Substances 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
210000003855 cell nucleus Anatomy 0.000 description 1
210000003679 cervix uteri Anatomy 0.000 description 1
238000004042 decolorization Methods 0.000 description 1
230000008021 deposition Effects 0.000 description 1
238000013461 design Methods 0.000 description 1
238000003745 diagnosis Methods 0.000 description 1
238000005553 drilling Methods 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
210000003743 erythrocyte Anatomy 0.000 description 1
238000005429 filling process Methods 0.000 description 1
238000005194 fractionation Methods 0.000 description 1
230000005484 gravity Effects 0.000 description 1
239000012535 impurity Substances 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
238000009434 installation Methods 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000000203 mixture Substances 0.000 description 1
229920001778 nylon Polymers 0.000 description 1
230000000149 penetrating effect Effects 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000000746 purification Methods 0.000 description 1
230000003068 static effect Effects 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000002699 waste material Substances 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
- G01N2001/2846—Cytocentrifuge method
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/111666—Utilizing a centrifuge or compartmented rotor

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Immunology (AREA)
Pathology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
General Physics & Mathematics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Sampling And Sample Adjustment (AREA)
Centrifugal Separators (AREA)
Investigating Or Analysing Biological Materials (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

JP58160609A 1982-09-02 1983-09-02 上皮細胞を細胞診断学的に検査する方法およびこの方法を実施するための遠心分離室 Granted JPS5965747A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3232581.9		1982-09-02
DE3232581		1982-09-02

Publications (2)

Publication Number	Publication Date
JPS5965747A JPS5965747A (ja)	1984-04-14
JPH0322943B2 true JPH0322943B2 (de)	1991-03-27

Family

ID=6172265

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP58160609A Granted JPS5965747A (ja)	1982-09-02	1983-09-02	上皮細胞を細胞診断学的に検査する方法およびこの方法を実施するための遠心分離室

Country Status (6)

Country	Link
US (1)	US4612873A (de)
EP (1)	EP0105194B1 (de)
JP (1)	JPS5965747A (de)
AT (1)	ATE34618T1 (de)
CA (1)	CA1213200A (de)
DE (1)	DE3376763D1 (de)

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DE3316336C2 (de) *	1983-05-04	1985-03-07	Fa. Andreas Hettich, 7200 Tuttlingen	Zentrifugationskammer mit lösbarer Trägerplatte
DE3706998A1 (de) *	1987-03-05	1988-09-15	Hettich Andreas Fa	Zentrifugationskammer zur zytologischen untersuchung von zellsuspensionen
JPH03247276A (ja) *	1990-02-27	1991-11-05	Hitachi Ltd	細胞の配列方法及び装置
DE9107153U1 (de) *	1991-05-14	1992-06-25	Fa. Andreas Hettich, 7200 Tuttlingen	Zentrifugationskammer, insbesondere zur Liquor-Untersuchung
US6048734A (en) *	1995-09-15	2000-04-11	The Regents Of The University Of Michigan	Thermal microvalves in a fluid flow method
US6008009A (en) *	1998-04-17	1999-12-28	Universities Space Research Association	Centrifuge-operated specimen staining method and apparatus
US6692700B2 (en)	2001-02-14	2004-02-17	Handylab, Inc.	Heat-reduction methods and systems related to microfluidic devices
US6743632B2 (en)	2001-03-14	2004-06-01	Universities Space Research Association	Directional acceleration vector-driven displacement of fluids (DAVD-DOF)
US7829025B2 (en)	2001-03-28	2010-11-09	Venture Lending & Leasing Iv, Inc.	Systems and methods for thermal actuation of microfluidic devices
US6852287B2 (en)	2001-09-12	2005-02-08	Handylab, Inc.	Microfluidic devices having a reduced number of input and output connections
US7010391B2 (en)	2001-03-28	2006-03-07	Handylab, Inc.	Methods and systems for control of microfluidic devices
US7323140B2 (en)	2001-03-28	2008-01-29	Handylab, Inc.	Moving microdroplets in a microfluidic device
US8895311B1 (en)	2001-03-28	2014-11-25	Handylab, Inc.	Methods and systems for control of general purpose microfluidic devices
US7666661B2 (en)	2001-08-27	2010-02-23	Platypus Technologies, Llc	Substrates, devices, and methods for quantitative liquid crystal assays
WO2003104801A1 (en) *	2002-04-13	2003-12-18	Newport Instruments	Centrifugal cytology system, chamber block and method for the preparation of treated monolayers of sample material
WO2004041061A2 (en) *	2002-05-22	2004-05-21	Platypus Technologies, Llc	Substrates, devices, and methods for cellular assays
EP1654390B1 (de) *	2003-07-25	2009-11-11	Platypus Technologies, LLC	Analytnachweis auf flüssigkristallbasis
EP1654066B1 (de)	2003-07-31	2014-11-12	Handylab, Inc.	Verarbeitung von teilchenhaltigen proben
EP1687396A2 (de)	2003-11-10	2006-08-09	Platypus Technologies, LLC	Substrate, vorrichtungen und verfahren für zelltests
EP1693675A4 (de) *	2003-12-08	2013-09-18	Wako Pure Chem Ind Ltd	Reaktionsscheibe und trennzelle zur verwendung in einem analyseautomaten
EP2345739B8 (de)	2004-05-03	2016-12-07	Handylab, Inc.	Mikrofluidische Vorrichtung zur Verarbeitung polynukleotidhaltiger Proben
US8852862B2 (en)	2004-05-03	2014-10-07	Handylab, Inc.	Method for processing polynucleotide-containing samples
US7662572B2 (en)	2005-08-25	2010-02-16	Platypus Technologies, Llc.	Compositions and liquid crystals
US8088616B2 (en)	2006-03-24	2012-01-03	Handylab, Inc.	Heater unit for microfluidic diagnostic system
US10900066B2 (en)	2006-03-24	2021-01-26	Handylab, Inc.	Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en)	2006-03-24	2011-08-16	Handylab, Inc.	Microfluidic system for amplifying and detecting polynucleotides in parallel
US9040288B2 (en)	2006-03-24	2015-05-26	Handylab, Inc.	Integrated system for processing microfluidic samples, and method of using the same
US11806718B2 (en)	2006-03-24	2023-11-07	Handylab, Inc.	Fluorescence detector for microfluidic diagnostic system
US7842499B2 (en) *	2006-08-07	2010-11-30	Platypus Technologies, Llc	Substrates, devices, and methods for cellular assays
WO2008021071A2 (en) *	2006-08-07	2008-02-21	Platypus Technologies, Llc	Substrates, devices, and methods for cellular assays
WO2008061165A2 (en)	2006-11-14	2008-05-22	Handylab, Inc.	Microfluidic cartridge and method of making same
WO2008060604A2 (en)	2006-11-14	2008-05-22	Handylab, Inc.	Microfluidic system for amplifying and detecting polynucleotides in parallel
US7758816B2 (en) *	2007-03-01	2010-07-20	Wescor Inc.	Large area cytocentrifuge sample chamber
US8133671B2 (en)	2007-07-13	2012-03-13	Handylab, Inc.	Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US9618139B2 (en)	2007-07-13	2017-04-11	Handylab, Inc.	Integrated heater and magnetic separator
US8287820B2 (en)	2007-07-13	2012-10-16	Handylab, Inc.	Automated pipetting apparatus having a combined liquid pump and pipette head system
US8182763B2 (en)	2007-07-13	2012-05-22	Handylab, Inc.	Rack for sample tubes and reagent holders
US8105783B2 (en)	2007-07-13	2012-01-31	Handylab, Inc.	Microfluidic cartridge
ES2648798T3 (es)	2007-07-13	2018-01-08	Handylab, Inc.	Materiales de captura de polinucleótidos y métodos de utilización de los mismos
US9186677B2 (en)	2007-07-13	2015-11-17	Handylab, Inc.	Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
USD621060S1 (en)	2008-07-14	2010-08-03	Handylab, Inc.	Microfluidic cartridge
US20090136385A1 (en)	2007-07-13	2009-05-28	Handylab, Inc.	Reagent Tube
EP2193365A4 (de)	2007-08-20	2015-05-13	Platypus Technologies Llc	Verbesserte vorrichtungen für zelltests
USD618820S1 (en)	2008-07-11	2010-06-29	Handylab, Inc.	Reagent holder
USD787087S1 (en)	2008-07-14	2017-05-16	Handylab, Inc.	Housing
EP2264424B1 (de)	2009-06-19	2013-08-21	Switch bvba	Zentrifugationseinheit mit Twist-fit-Verbindung
CN106190806B (zh)	2011-04-15	2018-11-06	贝克顿·迪金森公司	扫描实时微流体热循环仪和用于同步的热循环和扫描光学检测的方法
USD692162S1 (en)	2011-09-30	2013-10-22	Becton, Dickinson And Company	Single piece reagent holder
DK2761305T3 (da)	2011-09-30	2017-11-20	Becton Dickinson Co	Forenet reagensstrimmel
WO2013067202A1 (en)	2011-11-04	2013-05-10	Handylab, Inc.	Polynucleotide sample preparation device
DK2810080T3 (da)	2012-02-03	2024-06-17	Becton Dickinson Co	Eksterne filer til fordeling af molekylære diagnostiske tests og bestemmelse af kompatabilitet imellem tests
JP2018142671A (ja) *	2017-02-28	2018-09-13	株式会社村田製作所	インダクタ

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US3977598A (en) *	1973-05-24	1976-08-31	Mcdonald Bernard	Centrifuge tube
US3994594A (en) *	1975-08-27	1976-11-30	Technicon Instruments Corporation	Cuvette and method of use
NL7613690A (nl) *	1976-12-09	1978-06-13	Cenco Instr Bv	Cytocentrifuge.
US4175860A (en) *	1977-05-31	1979-11-27	Rush-Presbyterian-St. Luke's Medical Center	Dual resolution method and apparatus for use in automated classification of pap smear and other samples
US4241005A (en) *	1979-02-21	1980-12-23	The Trustees Of Boston University	Process for producing a molecularly oriented film
US4423699A (en) *	1979-02-28	1984-01-03	E. I. Du Pont De Nemours & Co.	Centrifuge rotor apparatus for preparing particle spreads
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US4344560A (en) *	1979-11-02	1982-08-17	Asahi Kasei Kogyo Kabushiki Kaisha	Container, apparatus and method for separating platelets
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US4327661A (en) *	1980-08-05	1982-05-04	E. I. Du Pont De Nemours And Company	Chamber block having a supernatant collection receptacle therein

1983
- 1983-08-31 DE DE8383108568T patent/DE3376763D1/de not_active Expired
- 1983-08-31 EP EP83108568A patent/EP0105194B1/de not_active Expired
- 1983-08-31 AT AT83108568T patent/ATE34618T1/de not_active IP Right Cessation
- 1983-09-02 US US06/529,126 patent/US4612873A/en not_active Expired - Fee Related
- 1983-09-02 CA CA000436034A patent/CA1213200A/en not_active Expired
- 1983-09-02 JP JP58160609A patent/JPS5965747A/ja active Granted

Also Published As

Publication number	Publication date
DE3376763D1 (en)	1988-06-30
CA1213200A (en)	1986-10-28
JPS5965747A (ja)	1984-04-14
EP0105194B1 (de)	1988-05-25
EP0105194A1 (de)	1984-04-11
US4612873A (en)	1986-09-23
ATE34618T1 (de)	1988-06-15

Publication	Publication Date	Title
JPS5965747A (ja)	1984-04-14	上皮細胞を細胞診断学的に検査する方法およびこの方法を実施するための遠心分離室
US6544162B1 (en)	2003-04-08	Semi-continuous, small volume centrifugal blood separator and method of using therefor
US10406265B2 (en)	2019-09-10	Method and device for isolating tissue cells from a liquid
US9101925B2 (en)	2015-08-11	Centrifuge and separation vessel therefore
US9095798B2 (en)	2015-08-04	Centrifuge separation method and apparatus using a medium density fluid
CN113634124B (zh)	2022-11-18	用于处理和分析通过切向过滤提取的颗粒的方法和装置
SK138394A3 (en)	1995-06-07	Method for separating of liquid sample and device for realization of this method
US11338283B2 (en)	2022-05-24	Kit for centrifugal separation of biological fluid components and a method for centrifugal separation of biological fluid components
JP2810545B2 (ja)	1998-10-15	液体サンプルおよびその成分の吸引装置、ならびに、それらと併用するスライドアセンブリ
JPH08508395A (ja)	1996-09-10	細胞学検査用単層採取のための方法と装置
JP7110344B2 (ja)	2022-08-01	細胞検査装置及び細胞検査方法
CN102869761A (zh)	2013-01-09	再生细胞提取系统
JP4412029B2 (ja)	2010-02-10	密度勾配遠心分離による微生物抽出方法
US5645715A (en)	1997-07-08	Collection tip for fractionating solution gradients
CN114371052A (zh)	2022-04-19	一种液基细胞样本制作装置
US20050260100A1 (en)	2005-11-24	Centrifugal cytology system, chamber block and method for the preparation of treated monolayers of sample material
US2461674A (en)	1949-02-15	Centrifuge apparatus for obtaining blood plasma
US4003834A (en)	1977-01-18	Density gradient fractionation by piston displacement
CN113646419A (zh)	2021-11-12	用于提取目标物质的提取装置、提取方法和流体芯片
JPH09143081A (ja)	1997-06-03	血漿分離フィルター、それを用いる血漿分離方法および血漿分離装置
US4863582A (en)	1989-09-05	Process and apparatus for purifying and concentrating DNA from crude mixtures containing DNA
WO2022190017A1 (en)	2022-09-15	Off-chip pressure-controlled centrifugal microfluidic fractionation
KR20210043219A (ko)	2021-04-21	광경화성 하이드로겔을 이용한 pbmc 분리 디스크
JPH11281535A (ja)	1999-10-15	細胞洗浄装置
JPS583658A (ja)	1983-01-10	液体成分の分離，分取，排出用遠心ロ−タ−