JPH04201425A - Rate of liquid efflux amount controlling member and preparation thereof - Google Patents

Abstract

PURPOSE:To make it possible to perform precisely and with a simple constitution control of the efflux amt. of a liq. by providing a synthetic resin layer on the surroundings of a metal fine pipe having an inner diameter and a length controlling flow rate of a fluid at a specified value and providing a controlling member main body consisting of a synthetic resin being brought into close contact with the surroundings. CONSTITUTION:A metal fine pipe 71 is prepd. by passing a raw material pipe through a dice with a successively narrowed diameter. The surroundings of this metal fine pipe 71 is coated with a synthetic resin layer 72 by using a cross-head type extruder. The obtd. resin-coated metal fine pipe 70 is cut into a specified length and if necessary, folding thereof is performed. This is kept in a mold and a controlling member main body 21 is integrally molded by injecting or casting a synthetic resin to communicate an end side of the metal fine pipe with an inlet 22 of a fluid and another end side with an outlet 23 of the fluid. By coating the surroundings of the metal fine pipe with the synthetic resin 72, it is possible to form the fine pipe 70 relatively thick even when an extremely thin metal fine pipe 71 is used and thereby to mount easily it to the mold, to make fusion with the controlling member main body 21 strong and to prevent a chem. liq. from leakage. In addition, the controlling member main body 21 which is molded with a resin in advance and a resin-coated metal fine pipe 70 can be combined to form the title member.

Description

[Detailed Description of the Invention] [Field of Industrial Application] The present invention relates to a continuous drug injector that sequentially injects a drug stored in a drug (liquid) storage portion into a human body, or a lubricant,
The present invention relates to a liquid outflow control member that is used in a dispenser or the like that dispenses a test liquid or other liquid to a predetermined location, and that controls the outflow amount of the liquid when injecting the liquid from a liquid storage portion into a predetermined location.

[Background technology]

Conventionally, methods for continuously injecting drug solutions into the human body include manually or automatically supplying the drug solution stored in a syringe through a needle or catheter, or by naturally or automatically supplying the drug solution in an intravenous drip container. It is supplied automatically.

Continuous infusion of such drug solutions takes several minutes to several hours, and during this time, the syringe, etc. is connected to the needle, etc., which not only causes pain to the patient and restricts his/her movements. This also causes inconvenience for practitioners such as doctors and nurses, who have to hold syringes and check the amount of intravenous drip.

For this reason, it is small and does not restrict the movement of patients or practitioners.
Continuous drug infusion devices and continuous drug infusion catheters that are easy to handle have been developed (Japanese Unexamined Patent Publication No. 102252/1983,
Special Publication No. 61-51901, Special Publication No. 1987-114
(See Japanese Patent Laid-Open No. 62-11465).

All of these conventional drug solution continuous injectors have a balloon (bag) made of an elastic material, and one end of the balloon is provided with an inlet for allowing the drug solution to flow into the balloon, while the other end is provided with an inlet for allowing the drug to flow into the balloon. is provided with an outflow portion through which the chemical solution flows out, and a check valve is provided in the inflow portion to allow the flow of the chemical solution only in the inflow direction.

In such a configuration, the contraction force of the balloon causes
The medicinal solution stored in the balloon is made to flow out from the outflow portion and flow into the human body via a human body-attached device such as a syringe needle or catheter.

[Problem to be solved by the invention]

However, in these continuous drug injectors,
The flow rate at the outflow portion of the chemical solution cannot always be controlled sufficiently, which has been a major obstacle in practical use.

That is, the outflow amount control of the medicinal solution in JP-A-56-102252 is performed using a flow path (oral cavity) that communicates the inside and outside of the bag.
This is done using an extremely thin flow control element installed in the This flow rate control element consists of a relatively short straight pipe (details unknown), and although there is no specific description, it is thought that the flow rate is changed by changing the length and inner diameter. . However, it is difficult to make the length of the flow control element sufficiently large due to the state in which it is installed in the flow path, and it is considered to be difficult in manufacturing to make the inner diameter extremely thin. For this reason, depending on the type of medicinal solution,
Although it is necessary to supply extremely small amounts to the human body over a long period of time, the flow rate control element cannot sufficiently meet such demands.

In addition, the outflow amount control of the chemical liquid in Japanese Patent Publication No. 61-51901 involves changing the diameter of an injection hole formed through the tube wall of the tubular body to which the balloon is attached, or changing the diameter of the injection hole formed in the tubular body according to the internal pressure of the balloon. This is done by using a diaphragm that makes the area of the inner diameter of the outflow part variable. However, injection holes formed in the tube wall cannot adequately control the flow rate because the tube wall is thin, while diaphragms are difficult to manufacture and are not suitable for mass production, making them impractical.

Furthermore, in JP-A-62-11464, the outflow amount of the drug solution is controlled by changing the diameter of the thin tube (pore) formed in the tube wall along the axial direction of the catheter. Drilling axial holes in a catheter is itself difficult, and precise control is even more difficult.

In addition, the outflow amount control in JP-A No. 62-11465 involves installing a flow rate control valve at the chemical outlet and controlling the rate of flow control of this flow rate control valve, but in this case as well, precise control is difficult. Ta.

Furthermore, prior to filing this application, the applicant
989) On November 14th, an application was filed for an invention titled "Medicinal solution flow rate control member and method for manufacturing the same" (
(Patent Application No. 1-296353). In order to improve the drawbacks of the outflow control member described in each of the above-mentioned publications, the present invention divides the outflow control member into a plurality of partial members along the flow direction of the chemical solution, and also provides grooves in the divided surfaces. and these partial members are brought into close contact with each other. According to this invention, since the grooves are relatively easy to form, the outflow amount can be precisely controlled by appropriately setting the cross-sectional area and length of the grooves.

Although these prior applications can almost solve the conventional problems, there is a desire for an outflow control member that is improved or has a different configuration from that of the prior application, and a method for manufacturing the same.

In addition, there is a desire for a device that can control not only the outflow amount of chemical liquids but also general liquids.

SUMMARY OF THE INVENTION An object of the present invention is to provide a liquid outflow amount control member that can precisely control the amount of liquid flow pressure with a simple configuration.

[Means to solve the problem]

The liquid outflow control member according to the present invention uses a metal capillary in which pores are easily formed to form the holes through which the liquid flows, and the control member with a predetermined external shape is molded with resin directly using the metal capillary. Since doing so is difficult to handle, a metal capillary whose circumferential surface is coated with resin in advance is used.

Specifically, the present invention provides a resin-coated metal capillary in which a synthetic resin layer is provided around a metal capillary having an inner diameter and length that regulates the flow rate of liquid to a predetermined value, and the resin-coated metal capillary is A liquid outflow amount control characterized in that a control member body made of synthetic resin is provided in close contact with the circumference of a thin metal tube, and one end of the metal thin tube is communicated with a liquid inlet, and the other end of the metal tube is communicated with a liquid outlet. It is a member.

The method for manufacturing a liquid outflow control member according to the present invention includes forming a resin-coated metal capillary by coating a long metal capillary tube with a synthetic resin layer to a predetermined thickness by extrusion molding, and forming a resin-coated metal capillary tube. After cutting to a predetermined length, the cut resin-coated metal thin tube is placed in an injection mold so that one end communicates with the liquid inlet and the other end communicates with the liquid outlet. It is characterized in that the control member body is molded by injecting a synthetic resin that has adhesive properties with the synthetic resin layer into the control member body.

Different methods of manufacturing the liquid outflow control member according to the present invention include:
A plurality of partial members that are divided into a plurality of parts along the liquid flow direction and each of which has a groove formed on at least one mating surface are made of synthetic resin, and the groove is formed on the mating surface of these partial members. A metal capillary tube of a predetermined length coated with a synthetic resin layer is fitted inside the tube, and each of these partial members, the resin-coated metal capillary tube, and each partial member are closely joined to each other.

[Effect]

In the liquid outflow control member according to the present invention configured as described above, the amount of liquid flowing in from the liquid inlet is regulated by the cross-sectional area and length of the metal capillary tube, and then flows out from the liquid outlet.

The metal thin tube used in the present invention can be made by passing stainless steel pipes etc. through successively smaller diameter dies, so that the inner diameter can be reduced to several tens of μm.
It can be formed into a small diameter of about m. By using this metal thin tube coated with synthetic resin, it can be easily joined to the control member main body made of synthetic resin, allowing for mass production and stabilization of quality. In addition, the resin-coated metal thin tube can be bent into any suitable shape, such as a straight line, a U-shape, or a zigzag shape, and by making its inner diameter a predetermined diameter and length,
The outflow amount of liquids such as chemical solutions can be controlled extremely easily.

5 Examples] Embodiments of the present invention will be described below based on the drawings.

1 to 3 show an embodiment in which a liquid outflow control member according to the present invention is applied to a continuous drug injector.

In FIG. 1 showing the overall configuration, a continuous drug injector 10 according to this embodiment includes a substantially cylindrical liquid outflow control member 20 made of synthetic resin. It is preferable that the control member 20 be made of a transparent or semi-transparent material in order to visually check the inside.

At one end of the liquid outflow control member 20, the right end in the figure, there is a liquid injection part 1 to which a syringe 12 as a liquid supply means can be attached.
3 is provided. Inside the liquid injection part 13, a liquid outflow prevention means 1 is provided which prevents the medicinal liquid injected from the syringe 12 into the control member 20 from flowing out from the liquid injection part 13.
4 is tightly fixed. The liquid outflow prevention means 14 is composed of a check valve that allows only the flow of the chemical liquid in the direction of arrow P or a cock that can open and close the flow path 13A of the liquid injection part 13. These check valves or cocks are commercially available. can be used.

The liquid outflow control member 20 includes a control member main body 21 made of synthetic resin or the like, and a resin-coated metal capillary tube 70 for flow rate control that is integrally provided inside the main body 21. One end of this thin tube 70, the upper tip bent in a left-hand shape in FIG.
At the other end, the tip located on the left side in FIG. 1, the end of the thin tube itself is used as a liquid outlet 23.

The thin tube 70 is, for example, bent into a substantially U-shape as shown in the figure to ensure a predetermined length, and the inner diameter of the thin tube 70 is, for example, several 10. czm to several hundred μm, and by appropriately selecting this length and inner diameter, the thin tube 7
It is possible to control the outflow amount of the chemical solution flowing through the chamber.

As shown in FIG. 2, the resin-coated metal capillary tube 70 has a synthetic resin layer 72 of a predetermined thickness coated on the circumferential surface of a metal capillary tube 71 made of stainless steel, chrome steel, or other metal material by extrusion molding or the like. It is composed of

As the synthetic resin for the resin layer 72 and the control member main body 21, silicone resin, acrylic, polycarbonate (P
C), polyethylene (PE), polypropylene (P
P), polyacetal (POM), polyamide (P)
A) Fluororesin, Bakelite, and other thermoplastic and thermosetting resins can be used, but they are thermoplastic, have good injection moldability and extrusion moldability, and are stable against liquids such as chemicals. , materials with some degree of translucency, such as polycarbonate, are preferred. In addition, the synthetic resin layer 72
It is preferable that the control member body 21 and the control member main body 21 are made of resin that has weldability to each other during molding of the control member 21, and it is more preferable that both of them are made of the same resin. Furthermore, when the resin-coated metal thin tube 70 is bent and formed as shown in FIG. 1, it is more preferable to use a flexible resin.

A plurality of communication holes 24 communicating with the outer surface of the liquid outflow control member 20 are formed in the flow path 27 . A circumferential groove 25 is formed at the outer circumferential opening position of each of these communication holes 24.
is formed so that the chemical solution can easily flow in and out through the communication hole 24.

In addition, among the communication holes 24, the communication hole 24L at the left end in the figure is
It is provided with a large diameter. As a result, the control member main body 21
A holder (not shown) for holding the upper end of the resin-coated metal capillary tube 70 inserted into the main body 21 in the mold when integrally molding the resin-coated capillary tube 70 with the resin-coated capillary tube 70 using a mold (not shown). can be inserted through this large diameter communication hole 24L.

A cylindrical rubber-like elastic membrane 31 is attached to the outer periphery of the control member 20 so as to cover all the communicating holes 24 of the control member 20. Both ends 31A of this rubber-like elastic membrane 31
is airtightly fixed to the outer periphery of the control member 20 with an adhesive or the like, and its intermediate portion 31B can be separated from the outer periphery of the control member 20. The rubber-like elastic membrane 31 is preferably made of a material with high elasticity and abrasion resistance and high toughness that is not easily damaged by external action, and in particular, transparent or translucent materials are preferable. . Suitable materials for the rubber-like elastic membrane 31 include, for example, commercially available silicone rubber or latex rubber.

The rubber-like elastic membrane 31 is made expandable as shown by the two-dot chain line in FIG. 1 by the inflow of a chemical solution through the communication hole 24. This expanded rubber-like elastic membrane (balloon)
31 constitutes a means for pressurizing the medicinal solution (liquid), and the inside of this expanded rubber-like elastic membrane 31 and the control member 20
A liquid storage section 35 is configured inside.

A cock 40 serving as an opening/closing means is detachably attached to the other end of the liquid outflow control member 20. This cock 40 is attached to the other end of the control member 20 and has a cock body 4 having a flow path 41A communicating with the liquid outlet 23.
1, and a knob 42 that is rotatably attached to the cock body 41 and has a communication hole 42A that can communicate with the flow path 41A.

Therefore, by rotating the knob 42, the flow path 4
1A can be blocked or communication can be performed through the communication hole 42A. In the state shown in FIG. 1, the communication hole 42A is arranged in a direction perpendicular to the flow path 4IA, and the flow path 41A is in a blocked state.By rotating the knob 42 by 90 degrees from the state shown, the flow path 41A is now open to traffic.

The cock body 41 has connectors 45.4 at both ends.
An injection needle 50 as a human body attachment device is removably attached via a flexible connecting tube 47 having a diameter of 6.

This injection needle 50 is commercially available and is composed of a mounting portion 51 that can be mounted on one connector 46 of the connecting tube 47 and a needle tip 52 that is implanted in the mounting portion 51.

In addition, in FIG. 1, the rubber-like elastic membrane 3 expanded into a spherical shape
A transparent cover 38 is attached as necessary to cover the outer diameter of the rubber-like elastic membrane 31 in an inflated state.
and can be attached to the patient.

Next, an example of the manufacturing method of this embodiment will be described.

The metal capillary tube 71 is manufactured by passing the raw material tube for the metal capillary tube 71 through a die whose hole diameter is successively reduced to a predetermined inner diameter. A commercially available metal tube 71 can be used.

In addition, for manufacturing the resin-coated metal thin tube 70, for example, a third
A so-called crosshead type extrusion molding machine 8 as shown in the figure
0 is used. This extrusion molding machine 80 is equipped with a crosshead 81, and inside this crosshead 81 is a thin metal tube 7.
1 and a nipple holder 83 that holds this nipple 82 are provided.
A die 84 is attached to the crosshead 81 opposite to the crosshead 2.

A molten resin 88 is supplied into the crosshead 81 from the screw 87 side of the extruder main body 86 via a breaker plate 85, and this molten resin 88 is applied to the circumferential surface of the thin metal tube 71 that is sequentially transferred within the die 84. It is coated with a synthetic resin layer 72 to form a continuous resin-coated metal thin tube 70.

In order to increase the strength of the welding between the thin metal tube 71 and the synthetic resin layer 72, the surface of the thin metal tube 71 is subjected to surface roughening treatment such as knurling or sandblasting, or to a known method for metal-resin adhesion such as epoxy treatment. method may be applied.

The continuous long resin-coated metal thin tube 70 formed as described above is cut into a predetermined length and then bent into a predetermined shape as necessary. This processed thin tube 70 is held in a mold for injection molding, injection molding, etc. (not shown) in a state in which resin does not flow into each end. In this state, the aforementioned synthetic resin is injected or injected into the mold, whereby the control member main body 21 is molded integrally with the resin-coated metal capillary tube 70 having the synthetic resin layer 72, and the liquid outflow control member 20 is manufactured. be done.

A rubber-like elastic member 31 is fitted onto the circumferential surface of the liquid outflow amount control member 20, and both ends 31A are fixed to the control member 20. Furthermore, a liquid injection part 13 is attached to the control member 20. The continuous drug injector 10 is completed.

Next, the operation of this embodiment will be explained.

A cock 40 as an opening/closing means is attached to one end of the control member 20 of the continuous drug injector 10, and the knob 4 of the cock 40 is attached to one end of the control member 20.
2 as shown in FIG. 1 to bring it into the closed state. In this state, the syringe 12 as a liquid supply means is attached to the liquid injection part 13 of the control member 20, and the medicinal liquid previously measured and stored in the syringe 12 is injected in the direction of arrow P.

The injected chemical liquid flows into the flow path 27 from the liquid inlet 22 of the control member 20 via the liquid outflow prevention means 14 . At this time, since the cock 40 attached to the liquid outlet 23 side of the control member 20 is in a closed state, the outflow of the chemical solution from the liquid outlet 23 is stopped. Therefore, the chemical liquid flows through the flow path 27 through the liquid inlet 22 of the outflow amount control member 20.
It flows into the rubber-like elastic membrane 31 through each communication hole 24 formed in the , and expands the rubber-like elastic membrane 31 into a spherical shape. As a result, the rubber-like elastic membrane 31 applies a predetermined pressure to the medical solution as a pressurizing means by the contraction force as a reaction force due to its expansion, and the inside of the control member 20 and the inside of the expanded rubber-like elastic membrane 31 become liquid. This is referred to as a storage section 35.

Moreover, the liquid medicine filled in the rubber-like elastic membrane 31 does not flow back from the liquid injection part 13 due to the action of the liquid outflow prevention means 14 provided in the liquid injection part 13.

If it is necessary to prevent air from entering the liquid outflow control member 20 and the rubber-like elastic membrane 31, the same type of chemical solution, physiological saline, or a predetermined liquid may be injected into the control member 20 in advance. Alternatively, after injecting the liquid, if the control member 20 is stood upright with the liquid injection part 13 facing upward, air bubbles in the rubber-like elastic membrane 31 and the control member 20 can be removed from the control member 20.
floats to the liquid injection part 13 side. Therefore, by inserting an air vent thin tube (not shown) into the liquid injection part 13 and opening the liquid outflow prevention means 14, the air can be easily discharged.

After injecting a predetermined amount of the drug into the continuous drug injector 10 as described above, the injection needle 50 as a body-worn device is attached to the cock 40 via the connecting tube 45 as necessary. Preparations for inserting it into the human body and injecting the medicinal solution into the human body are completed.

Before inserting the injection needle 50 into the human body, the medicinal solution is allowed to flow out of the injection needle 50 as necessary, and a normal air bleeding operation is performed.

After inserting the injection needle 50 into the human body, the knob 42 of the cock 40
When rotated to open the flow path 41A through the communication hole 42A, the medicinal solution stored in the liquid storage section 35 and pressurized by the rubber-like elastic membrane 31 as a pressurizing means is transferred to the entire circumferential groove 25.
, flows into the resin-coated metal capillary tube 70 of the liquid outflow amount control member 20 through the communication hole 24 and the circulation hole 27 . The chemical solution that has flown into the liquid outflow amount control member 20 is controlled in its outflow speed, or in other words, the outflow amount, by the inner diameter and length of the resin-coated metal capillary tube 70, and the flow path 40 of the cock 40 is controlled.
A, flows out in the direction of arrow T, and further flows into the human body (not shown) via the connecting tube 47 and injection needle 50. At this time, since the outflow amount of the chemical solution is controlled by the liquid outflow amount control member 20, a predetermined outflow time is maintained despite the pressing force of the expanded rubber-like elastic membrane 31.

The outflow time of the medicinal solution is determined by the injection amount of the medicinal solution, its viscosity, the elastic properties of the rubber-like elastic membrane 31, the inner diameter and length of the resin-coated metal capillary tube 70 of the liquid outflow amount control member 20, the pressure inside the human body to which it is injected, etc. . In reality, the value is determined by actually measuring the outflow time of a predetermined drug solution for each continuous drug solution injector 10.

According to this embodiment as described above, there are the following effects.

That is, the liquid outflow amount control member 20 according to this embodiment is as follows:
Since the structure includes a resin-coated metal capillary tube 70 whose inner diameter is precisely controlled by precision molding with a die, by appropriately setting the inner diameter and length of the capillary tube 70, extremely accurate outflow of the chemical solution can be achieved. It is possible to control the amount.

Furthermore, the inner diameter and length of the thin tube 70 can be set using the metal thin tube 71.
Since this process can be carried out by selecting the material and cutting, it can be mass-produced very easily, and the continuous drug injector IO itself can be manufactured at low cost.

Furthermore, since the length of the thin tube 71 can be made longer by bending it, the pore diameter can be increased by the longer length for the same amount of outflow control, and problems such as hole clogging occur. do not have.

Further, since the metal capillary tube 71 is coated with a synthetic resin layer 72 to form the resin-coated metal capillary tube 70, even if an extremely thin metal tube 71 is used, the thin tube 70 can be formed relatively thick, and the mold can be Easy handling such as installation. Furthermore,
Since the resin layer 72 is formed, when the control member main body 21 is resin-molded, the welding between the main body 21 and the thin tube 70 can be made strong, and leakage of the chemical liquid between the two can be sufficiently prevented.

In addition, since the continuous drug injector 10 of this embodiment can serve both of storing the drug and pressurized injection, the structure is small and
Moreover, it has the advantage of being easy to make and easy to handle. Therefore, the patient's behavior etc. are not restricted, and the labor and restraint time of the practitioner can be reduced. Furthermore, the liquid injection part 13 is provided with a liquid outflow prevention means 14, and since the continuous drug injector 10 has a sealed structure as a whole, once the air in the syringe IO is vented, the rubber-like elasticity Air intrusion does not occur until the membrane 31 is completely shrunk.

Further, since the rubber-like elastic membrane 31 is used as the pressurizing means, the structure is simple, and from this point of view as well, the device can be manufactured in a small size and light weight.

It should be noted that the present invention is not limited to the above-mentioned embodiments, and the present invention includes modifications within a range that can achieve the purpose of the present invention. In addition, in the modified examples of the present invention shown below, the same or equivalent components as in the above embodiments include:
The same reference numerals will be used to omit or simplify explanations of overlapping parts.

For example, as the liquid outflow control member 20, the control member main body 2 is attached around the resin-coated metal capillary tube 70 as in the above embodiment.
The control member main body 21 is not limited to being directly molded with resin, and may be created by combining the control member main body 21 molded with resin in advance and the resin-coated metal thin tube 70.

That is, FIG. 4 and FIG. 5 show a component diagram and a side view of the assembled state of the liquid outflow control member 20, which has a structure in which resin molding is performed in advance.

The control member main body 21 of the liquid outflow control member 20 in this embodiment has a plurality of partial members 21A, 21 divided approximately equally in this embodiment along the drug flow direction, that is, the direction of arrow P.
These partial members 21A and 21B are each independently formed from the same synthetic resin as described above by injection molding or the like.

Since the partial members 21A and 21B are formed symmetrically with respect to the mating surface 26 of both members, corresponding portions of both members will be described with reference numeral A or B, respectively.

The partial members 21A and 21B have grooves 2 for forming flow passages 27.
7A, 27B and grooves 28A, 28B for mounting U-shaped resin-coated metal thin tubes 70, respectively, and these grooves 28A.

Inlet portions 22A, 22B and outlet portion 23 corresponding to liquid inlet 22 and liquid outlet 23 are provided at one end and the other end of 28B.
A, 23B, and further includes partial members 21A, 21
B has concave grooves 24A, 24B and 25A, 25B for forming a communication hole 24 and a circumferential groove 25.

The partial members 21A, 21B have grooves 28A, 28
A resin-coated metal capillary tube 70 is joined into either one of B by an appropriate joining means. Thereafter, as shown in FIG. 5, each partial member 21A, 21B is faced to each other so that their symmetrical shapes match at the mating surface 26A.
, 26B are joined by suitable joining means. Although ultrasonic welding is preferable as the above-mentioned joining means, other means such as adhesion may be used as long as it can effectively prevent the adhesive from flowing into the thin tube 7o.

Further, as the liquid outflow amount control member 20, in order to attach the thin tube 70, the mating surface 26A of each partial member 21A, 21B as in the embodiment shown in FIGS. 4 and 5 is used.

The grooves 28A and 28B are not limited to being provided on both of the parts 26B, but as shown in FIG. 6, in this embodiment, the grooves 28A may be provided only on the mating surface 26A of the partial member 2OA. . At this time, the groove 24A for the communication hole 24 is also provided only in one partial member 21A, and the mating surface 26B of the other partial member 21B is made flat. Further, the synthetic resin layer 71 of the resin-coated metal thin tube 70 has a substantially horseshoe-shaped cross section in accordance with the shape of the groove 28A. If formed like this,
Since the mating surface 26B on one side of the partial members 21A, 21B is a flat surface, the positioning of the image portion members 21A, 21B becomes easy, and the joining operation can be performed quickly.

Furthermore, as shown in FIG. 7, the liquid inlet 22 is not directly connected to the flow path 27, but passes between the flow path 29, the outer periphery of the liquid outflow control member 20, and the rubber-like elastic membrane 31, Furthermore, it may be communicated with the flow path 27 through the circumferential groove 25 and the communication hole 24, and even if formed in this way, the same effect as the embodiment shown in FIG. 1 can be achieved.

In addition, the pressurizing means is not limited to the rubber-like elastic membrane 31;
Other pressurizing means may also be used.

Furthermore, the position at which the rubber-like elastic membrane 31 is attached to the liquid outflow control member 20 is not limited to the middle of the control member 20, but may be at one end as shown in FIG. In this case, the rubber-like elastic membrane 31 is fitted into a cylindrical elastic membrane holder 33 made of synthetic resin, and a plurality of communication holes 24 are formed in the elastic membrane holder 33, and a control hole is formed at one end of the holder 33. Member 20
However, a liquid injection part 13 is attached to the other end. At this time, the control member 20 is not formed with a circumferential groove or a communication hole.

In addition, in FIG. 8, the elastic membrane holder 33 is removed,
In addition, the other end of the rubber-like elastic membrane 31 is closed to form the rubber-like elastic membrane 31 into a bag shape, while the liquid injection part 13 is branched from the middle of the control member 20 and the flow path 13A is connected to the flow path 27.
It goes without saying that it may be communicated with the thin tube 70 via a.

Further, depending on the flow rate of the chemical liquid, the thin tube 70 may be provided as a one-pass groove connecting the liquid inlet 22 and the liquid outlet 23 in a straight line, as shown in FIG. There is no need to bend it. This straight shape has the advantage that the thin tube 70 can be easily installed into the control member body 21, and the material for the elongated control member body 21 into which the thin tube 70 is inserted can be prepared in advance. This can also be created into a predetermined shape by machining using a lathe or the like. On the other hand, the embodiment shown in FIG. 9 is disadvantageous in that the length dimension becomes large.

Moreover, in FIG. 10.11, it has a linear thin tube 70,
Moreover, an embodiment is shown which eliminates the drawback of the embodiment shown in FIG. 9, which is large in size.

That is, in FIG. 10, the control member main body 21 is formed to be thinner on the inlet 22 side, and
A plurality of radially projecting end holding protrusions 218, for example, three radially projecting protrusions 218, are formed at the side ends. A bottomed cylindrical elastic membrane holder 33 is fitted onto the outer edge of the protrusion 218 .
3 and the control member main body 21 having a small diameter is a flow path 2.
7 is formed. The flow path 27 communicates with the inner surface of the rubber-like elastic membrane 31 via a large number of communication holes 24 provided in the elastic membrane holder 33. Further, a liquid injection part 1 having a liquid outflow prevention means 14 is provided at the bottom of the cylinder of the elastic membrane holder 33.
3 is fixed.

According to the embodiment shown in FIGS. 10 and 11, the disadvantage of the large size of the embodiment shown in FIG. 9 can be overcome.

In short, the regulation of the flow rate of liquids such as chemical solutions is determined by the inner diameter cross-sectional area and length of the thin tube 70, so the cross-sectional area and length of the thin tube 70 can be determined according to manufacturing needs. Its external shape does not matter.

Further, the control of the outflow amount by the liquid outflow amount control member 20 is as follows.
It can be applied not only to chemical liquids but also to all other liquids such as lubricants, test liquids, adhesives, etc.

Further, the liquid storage portion 35 is not limited to the inside of the expanded rubber-like elastic membrane 31 and the control member 20, but may be any place that can store a liquid such as a medicinal solution, and its shape is not limited.

Further, the shape of the liquid outflow amount control member 20 is not limited to a round bar shape, but may be other shapes such as a prismatic shape or a flat shape. Furthermore, the division of the control member 20 is not limited to approximately equal two divisions as in the embodiments shown in FIGS. 4 and 5, but may be divided into three or more plural divisions.
In this case, it is sufficient that the thin tube 70 is attached to at least one mating surface 26, but it may be provided to two or more mating surfaces 26.

However, in practice, dividing into two parts is advantageous in terms of ease of joining. Furthermore, the resin coating on the metal capillary tube 71 is not limited to the negative synthetic resin layer 72, but may include two or more resin layers 72.

At this time, it is preferable to select a material that has a high bonding strength with metal for the layer in contact with the circumferential surface of the thin metal tube 71.

As the liquid supply means, the syringe 1 as in the above embodiment is used.
The opening/closing means is not limited to the cock 40, but may be other means such as a metering discharge pump.
It may be a simple pinch that connects an elastic tube to 3 and clamps the elastic tube, or it may be a general on-off valve or the like.

Furthermore, the device to be worn on the human body is not limited to the injection needle 50 as in the above embodiment, but may also be an injection needle having a structure in which a flexible tube is interposed between the attachment portion 51 and the needle tip 52, or a catheter. It's okay. Of course, any type of catheter can be used, such as general venous catheters, urinary catheters, digestive catheters, obstetrics and gynecology catheters, and neurosurgical catheters.

The positions at which these various body-worn devices are attached are not limited to those that are attached to the liquid outlet 23 of the continuous drug injector 10 via the cock 40, but are also those that are attached directly to the outer periphery of the liquid outlet 23. In other words, it is sufficient as long as it is on the liquid outlet side.

〔Effect of the invention〕

According to the present invention as described above, there is an effect that precise control of the outflow amount of liquid can be performed with a structure that can be easily mass-produced.

[Brief explanation of the drawing]

FIG. 1 is a longitudinal sectional view showing an embodiment in which a liquid outflow control member according to the present invention is applied to a continuous drug injector, and FIG. 2 is a partially cutaway perspective view of a resin-coated metal thin tube used in the embodiment. Figure 3 is a sectional view showing an example of a method for manufacturing a resin-coated metal thin tube, and Figure 4 (A). (B) is a plan view of a partial member used in another embodiment of the liquid outflow control member, FIG. 5 is an enlarged side view showing the joined state of the partial member of FIG. 4, and FIG. An enlarged side view of a main part showing a modification of the embodiment shown in the figure; FIGS. 7 to 1θ are sectional views showing still other embodiments of the present invention,
FIG. 11 is a sectional view taken along the line XI-XI in FIG. 10. IO... Liquid drug continuous injector, 20... Liquid outflow control member, 21... Control member body, 21A, 21B...
Partial member, 22...Liquid inlet, 23...Liquid outlet, 24...Communication hole, 26.26A, 26B...Matching surface, 28A, 28B...Concave groove, 31... Rubber-like elastic membrane as pressurizing means, 70...resin-coated metal capillary,
71... Metal thin tube, 72... Synthetic resin layer.

Claims (3)

[Claims] (1) A synthetic resin layer is provided around a metal capillary tube having an inner diameter and length that regulates the flow rate of liquid to a predetermined value, making it a resin-coated metal capillary tube, and a synthetic resin layer is provided around the resin-coated metal capillary tube. A liquid outflow amount control member, characterized in that a control member main body consisting of the metal tube is provided in close contact with each other, and one end side of the metal capillary tube is connected to a liquid inlet, and the other end side is connected to a liquid outflow port. (2) A long metal capillary tube is coated with a synthetic resin layer to a predetermined thickness by extrusion molding to form a resin-coated metal capillary tube, and this resin-coated metal capillary tube is cut to a predetermined length. A resin-coated metal thin tube is placed in an injection mold so that one end communicates with a liquid inlet and the other end communicates with a liquid outlet, and a synthetic resin that is in close contact with the synthetic resin layer is placed in the injection mold. 1. A method for manufacturing a liquid outflow control member, comprising: molding a control member main body by injecting the liquid. (3) A plurality of partial members that are divided into a plurality of parts along the liquid flow direction and each having a groove formed on at least one mating surface are made of synthetic resin, and a plurality of partial members are formed on the mating surfaces of these partial members. A thin metal tube of a predetermined length coated with a synthetic resin layer is fitted into the groove, and each of these partial members, the resin-coated metal thin tube, and each partial member are closely joined to each other. A method for manufacturing a liquid outflow control member.