JPH042359A - Hollow yarn membrane type blood treatment apparatus - Google Patents

Abstract

PURPOSE:To prevent the generation of a thrombus or the mixing thereof with blood without bringing formed burr into contact with blood by pressing an annular elastomer by a blood port and a partition wall to deform the same so as to fill the annular space thereof. CONSTITUTION:A blood port 9 is subjected to injection molding and the mold forming the inner surface shape thereof is taken out before a resin is cooled and an annular elasmomer forming mold 40 is mounted to the blood port 9 to inject an annular elastomer molding resin in an annular recessed part 26 to form the blood port 9 wherein the annular elastomer is fixed to the annular recessed part 26. When the blood port 9 is mounted on a housing 2 and an annular elastic rib 20 is pressed along with the annular elastomer 17, a part of the annular elastomer 17 fills an annular space 32 and the contact possibility with blood is eliminated. Further, a part of the annular elastic rib 20 is deformed between the annular rib 22 of the blood port 9 and a partition wall 5 to seal both of the annular rib 22 and the partition wall 5 and the space between the annular rib 22 and the partition wall 5 is also reduced.

Description

Detailed Description of the Invention Industrial Application ytH The present invention is applicable to hollow fiber membrane type liquid processing such as hollow fiber membrane type artificial dialyzer, hollow fiber membrane type oxygenator, hollow fiber membrane type plasma separator, etc. Concerning vessels.

BACKGROUND OF THE INVENTION 1. Conventionally, many hollow fiber membrane type liquid treatment devices have been used. A typical example of this is the hollow fiber membrane type artificial dialysis machine, which has a hollow fiber membrane structure consisting of a large number of hollow fiber membranes for dialysis inside a cylindrical haununk that has an inlet and an outlet for dialysate. Both ends of the hollow fiber membrane bundle are fluid-tightly fixed to both ends of the cylindrical housing by partition walls formed with a boating agent, and blood flows outside of the partition walls. and a cap-like blood port forming a blood outlet. As the hollow fiber membrane for dialysis, a hydrophilic membrane such as regenerated cellulose such as cellulose acetate or cuprammonium cellulose is used, and as a potting agent, polyurethane or the like is used.

[Problems to be Solved by the Invention] Blood ports used in conventional hemodialysis devices have a blood inlet or a blood outlet and an annular recess. A cap-shaped blood inflow side blood port equipped with an O-ring formed by the above is fixed to the housing by an inseparable bolt or a boat hook.

However, [7] With such blood vessels, if the O-rings are not inserted correctly into the four annular parts during assembly of the dialysis machine, or the O-rings may become displaced during assembly, blood may leak. There was.

A method that solves these problems is disclosed in Japanese Utility Model Application Laid-open No. 61-63240. In this hollow fiber type mass transfer device, as shown in Fig. 10, an annular elastic body 54 is integrally molded on the inner surface of the cap-shaped blood bowl 1-50, and the tightening is performed directly without using a ring. Fixed to Hau/Fugu. If such a blood port 50 is used, the above-mentioned problems can be solved.For example, if the annular elastic body 54 is first molded and then the blood port 50 is molded by injection Sj, 58 The material used for molding the blood port 50 tends to be stiff in some parts. On the other hand, if the annular elastic body 54 is molded by injection after the blood vessel h50 is molded, the material used to mold the annular elastic body tends to be stiff at the 56 portion. Furthermore, since this stiffness comes into contact with blood during blood circulation, it may cause the formation of blood clots, and there is also the risk that it may separate from the blood port, mix in the blood, and flow into the body.

Means for Solving the Problems Therefore, an object of the present invention is to solve the problems of the prior art described above, and to maintain a fluid-tight state between the blood port and the septum without using an O-ring. be able to do so, and
The present invention provides a blood processing device that can prevent the formation of thrombi due to stiffness generated during blood circulation during blood circulation or molding of a blood port or annular elastic body, and furthermore, prevent the mixing of blood into the blood by removing the stiffness.

- A device that achieves the purpose described in F is a housing, a hollow fiber membrane bundle consisting of a large number of hollow fiber membranes for blood treatment inserted into the housing, and a blood treatment fluid provided near both ends of the housing. a blood inlet side blood port having an inlet and an outlet thereof, a partition wall that fixes both ends of the hollow fiber membrane bundle to both ends of the how/knob, and a blood inlet port attached to an end of one of the partition walls. and a blood outflow side blood port having a blood outflow port provided at the end of the other partition wall 2, and the two blood ports are connected to an annular recess formed in the inner periphery. , an annular arcuate body fixed to the annular recess, and an annular space formed between the annular elastic body and an annular rib forming an inner side surface of the annular recess of the blood port; BO! is a hollow fiber membrane type blood processing device in which the annular elastic body is fixed to the howling in a state where it is pressed against the partition wall.

Preferably, the annular elastic body is deformed by pressure to compensate for the annular space. Further, the annular elastic body has an annular elastic rib in a portion protruding outward from the annular recess of the Aii blood date, and the annular elastic rib forms an inner side surface of the annular recess of the blood port. It is preferable that the annular rib be compressed between the annular rib and the partition wall. Furthermore, the annular elastic rib protrudes from the central portion of the annular elastic body and has a diameter that decreases toward the outer side surface or the tip of the annular elastic rib, and the annular elastic rib becomes thinner toward the tip. It is preferable that

The annular elastic body protrudes from a center side portion of the annular elastic body, and the first rib is pressed between the partition wall and an annular rib that forms an inner side surface of the annular recess of the blood port.
a second annular elastic rib sandwiched between the partition wall and an N portion that protrudes from the outer side of the annular elastic body and forms an outer side surface of the annular recess of the blood port; It is preferable to have a sexual rib. Furthermore, it is preferable that the partition wall has a peripheral edge where no hollow fibers are present, and the annular elastic rib of the annular elastic body is in contact with the peripheral edge where no hollow fibers are present. . The hollow fiber membrane type blood processing device is, for example, a hollow fiber membrane type dialysis device. Further, it is preferable that the annular elastic body is integrally molded by a color molding method.

The hollow fiber membrane type liquid treatment device of the present invention will be explained using an embodiment shown in the drawings.

FIG. 1 is a partial sectional view showing an embodiment in which the hollow fiber membrane type liquid treatment device of the present invention is applied to a hollow fiber membrane type artificial dialyzer.
The figure is an enlarged sectional view of a blood vessel used in the hollow fiber membrane type blood processing device shown in FIG. 1.

The hollow fiber membrane type liquid treatment device 1 of the present invention includes a housing 2,
A hollow fiber membrane bundle 3 consisting of a large number of hollow fiber membranes for blood treatment inserted into the inside of the how/knob 2 and an inflow of blood treatment fluid provided near both ends of the how/knob 2 [,,,i
l 11 and an outlet 12, partition walls 5, 6 that fix both ends of the hollow fiber membrane to both ends of the how/knob 2, and a blood inflow side having a blood inflow lower attached to the end of one partition 5. The liquid port 9 and one end of the other corner wall 6]
Blood outflow side liquid port 1- with a cut blood outflow port 8
10, the blood bow 1-9.1.0 has an annular four part 26 provided on the inner periphery, an annular elastic body 17.18 fixed to the annular recess 26, and a blood port 9.10. The blood port 910 has an annular rib 22 forming the inner side surface of the annular portion 26 and an annular space 32 formed between the annular elastic body 17. 17 and 18 are fixed in a pressed state to the partition wall 5.6.

Here, the blood ports 9 and 10 have the same shape and mechanism, except for the blood flow direction, so the blood port 9 will be described below.

As described above, in the hollow fiber membrane type blood processing device of the present invention, as described above, the annular rib 22 forming the inner side surface of the annular recess 26 of the blood port 9 and the annular elastic bodies 17 and 18 are Since it has an annular space 32, the annular elastic body 17
The firmness that occurs when the blood port 9 is molded by injection after molding the annular elastic body 17 of the annular space 32
On the contrary, after forming the blood port 9,
Harness that occurs when the annular elastic body [7] is molded by injection is formed on the inner surface of the annular rib 22 of the annular space 32. The annular elastic body 17 is deformed by being pressed by the blood port 9.10 and the partition wall, and deforms to compensate for the annular space 32, as shown in FIG. There is no contact with blood during blood circulation, which prevents the occurrence of blood clots caused by stiffness.
It also prevents it from separating from the blood port, mixing with the blood, and flowing into the body.

Therefore, the liquid processing device 1 of the present invention will be explained using an embodiment of a hollow fiber membrane type artificial dialyzer shown in FIG.

This hollow fiber membrane type blood processing device 1 has a cylindrical housing 2
6,000 to 50,000 hollow fiber membranes 3 for dialysis are housed throughout the housing 2. Then, the openings at both ends of this hollow fiber membrane 3 for dialysis are closed.
In this state, the housing 2 is fluid-tightly fixed to the end portion of the housing 2 by partition walls 5 and 6. Due to the partition walls 5 and 6, the inside of the housing is divided into a dialysate chamber formed by the outer wall of the hollow fiber membrane 3 for dialysis, the inner wall of the housing 2, and the partition wall 5.6, and a blood chamber formed inside the hollow fiber membrane 3. It is divided into

The cylindrical housing 2 is made of polycarbonate, acrylonitrile-styrene copolymer, styrene, butane-styrene copolymer, etc., and has a cylindrical shape, preferably a cylindrical shape. has a dialysate inlet 11 on the side wall near one end, or a dialysate inlet 11 on the other end.
The outlet 12 is provided in the nearby side wall.

The hollow fiber membrane 3 for dialysis is a hollow fiber membrane for dialysis having hydrophilic properties formed of regenerated cellulose such as cellulose acetate, cuprammonium cellulose, cellulose derivatives, ethylene-vinyl alcohol copolymer, acrylonitrile copolymer, etc. and has a wall thickness of 5 to 35 μm, preferably 10 to 35 μm.
20 μm, outer diameter 50 to 500 μm, preferably 100 μm
~300 μm, and has a hollow portion extending through the entire length.

The partition walls 5 and 6 are formed of a botting agent such as polyurethane or briquette.

Preferably, the partition walls 5 and 6 have a portion in which no hollow fibers are present at their peripheral edges.

It is preferable that the annular elastic bodies 17 and 18, which will be described later, come into contact with the periphery where no hollow fibers are present. it is,
This is because if the annular elastic body 17, 18 comes into contact with a portion where hollow fibers are present, the hollow fibers in that portion will be blocked, making it impossible to effectively utilize the hollow fibers inserted into the housing.

Blood ports are attached to both ends of the housing l.

In the embodiment shown in FIG. 1, the blood ports 9 and 10 are
It has an attachment part 23 to the housing 2, and this attachment part 23 is fused and fixed to the housing 2 by high frequency, ultrasonic waves, or the like.

An elastic body 17.18 is fixed to the annular recess 26 of the blood port 9.10.

When the blood ports 9 and 10 are attached to the housing 2, the annular elastic bodies 17 and 18 are attached to the partition walls 5 and 5 at both ends of the housing.
6 and presses/ruts the peripheral edge of the partition wall.

As shown in FIG. 2, an annular recess 26 is provided on the inner peripheral edge of the blood port 9.
The side of 6 is an annular rib 2 provided inside the blood port.
2 and an inner side surface of the shoulder portion 24. The annular elastic body 17 is connected to this tubular recess 26.
It is designed to be filled with. Furthermore, the annular elastic body 17 protrudes in an annular manner to the outside of the annular recess 26, in other words, below the annular elastic body 7.
It has an annular space 32 between the annular rib 22 forming the inner side surface of the annular elastic body 17 and the annular elastic body 17 . The annular space 32 may have a width of 02 to 1, depending on the size of the blood port and the size of the annular elastic body. About 0mm, depth is 05π,
It is preferable that the depth is 7 or more and 374 or less, which is the depth of the annular recess 26 described later. Further, it is preferable that the annular elastic body 17 has a protruding annular elastic rib 20, as shown in FIG.

By providing such an annular elastic rib, as shown in FIG. 4, the annular elastic body 1a, especially the annular elastic rib 2
By being pressed, a part of the elastic rib 2o or
It is deformed between the annular rib 22 of the blood port 9 and the partition wall 5, and is compressed between the annular rib 22 and the partition wall 5, thereby ensuring a secure seal between the two. Furthermore, the space between the annular rib 22 and the partition wall 5 is also reduced, making it possible to prevent thrombus formation due to blood retention in this area. Specifically, it is preferable that the annular elastic rib 20 protrudes from the center side portion of the annular elastic body 17, and that the diameter of the annular elastic rib 20 decreases toward the outer side surface or the tip. By doing this, the annular elastic rib 20 becomes thinner toward the tip, and the annular elastic rib 20 becomes thinner toward the blood port 9.
Deformation toward the annular rib 22 side is ensured. More preferably, the outer side surface of the annular elastic rib 20 is recessed as shown in FIG.
・It is preferable to draw a circle. By doing this, the annular elastic rib 20 can be more easily
Easily deforms to the side. The shape of the annular elastic body 17 is not limited to the cross section shown in FIG. 3, but may be semicircular as shown in FIG. 9, rectangular, triangular, etc. The top surface or the bottom surface may be wider than the opening 26. - For boat fishing, the size of the annular recess 26 is as follows:
Preferably, the width is about 20 to 5.0 mm and the depth is about 10 to 3.0 mm. Further, the annular elastic rib 20 provided on the annular elastic body 17 preferably has a height of about 05 to 2.0 mm, and further, as shown in FIG. Width at base, 20-50m
m, the width at the tip is 2.5ml! It is preferable to set it to about the following. Further, it is preferable that the tip end surface of the annular elastic rib 20 be a curved surface or a substantially flat surface. Further, it is preferable that the inner side surface of the annular elastic rib 20 has a shape that does not hinder the deformation of the elastic rib 20, and more specifically, it is preferable that the inner side surface of the annular elastic rib 20 has a substantially flat surface. Furthermore, it is preferable that the inner surface end of the shoulder 24 of the blood port 9 forms a protrusion 36 . By forming such a protrusion 36, the annular elastic body 17 is securely fixed to the annular recess 26, and the material forming the blood port 9 and the material forming the annular elastic body are non-adhesive or have low adhesive properties. Even when a device is used, the annular elastic body 17 can be prevented from coming off from the annular recess 26 of the blood port.

In addition, instead of the protrusion 36 described above, the annular recess 26 or the shoulder 2 of the blood port 9 has a diameter that decreases toward the opening.
4 may be formed. From the standpoint of molding technology, the method of providing the above-mentioned protrusions is preferable.

Therefore, a method of forming such a blood port 9 will be briefly explained using FIG. 5.

First, the blood port 9 is molded in a mold by injection molding. Then, the mold in which the inner surface shape of the blood port 9 has been created is removed before the resin forming the blood port 9 is completely cooled, and the annular elastic body molding mold 40 is attached. This lawyer is shown in Figure 5. As shown in FIG. 5, the elastic body molding die 40 has a protruding rib 42 for forming an annular space and an annular protrusion 44 that bites into the shoulder of the blood port 9. This protrusion 44 or blood port 9
By biting into the annular recess 26, a protrusion 36 is formed on the inner surface of the shoulder portion of the annular recess 26. Alternatively, as shown in FIG. 6, by providing an annular projection 44 on the outside of the roughening annular recess 26 and attaching a mold 41 for forming the elastic body, the annular projection 44 can be
The protrusion 36 may be formed by tilting the inner side wall of the annular recess 26 toward the annular recess 26 . This protrusion 36 functions as a stop for the annular elastic body to be formed later. Subsequently, the annular elastic body molding resin is injected into the annular recess 26 and solidified, thereby forming the blood port 9 to which the annular elastic body is fixed. Further, when molded in this manner, a gap between the protruding rib 42 and the blood port 9 or a gap L1 may be formed.

Further, the annular elastic body 17 is limited to one using the annular elastic rib 20 as described above, for example, as shown in FIG. , Furthermore, a substantially rectangular shape may be used.

As shown in FIG. 4, which is a partially enlarged sectional view of the blood port 9 attached to the housing 2, the annular elastic rib 20 is pressed together with the annular elastic body 17, so that a part of the annular elastic body 17 is deformed to compensate for the annular space 32, so that there is no possibility of contact with blood. Therefore, the tension 60 is also covered by the annular elastic body.

Further, a part of the annular elastic rib 20 is deformed between the annular rib 22 of the blood port 9 and the partition wall 5, and is pinched by the lock between the annular rib 22 and the lock wall 5, resulting in a seal between the two. Ru. Furthermore, the space between the annular rib 22 and the partition wall 5 is also reduced.

Further, as shown in FIG. 7, the annular elastic body I7 protrudes from the center side portion of the annular elastic body 17, and is spaced between the annular first flap 22 forming the inner side surface of the annular recess 26 of the blood port 9 and the partition wall 5. It is sandwiched between the first annular elastic rib 20 which is pressed between the first annular elastic rib 20 and the septum 5 and the shoulder part 24 that protrudes from the outer part of the annular arch body 17 and forms the outer side surface of the annular recess 26 of the blood port 9. The second annular elastic rib may have a pressure of 4Ω.

FIG. 8 shows a partially enlarged cross-section of the mouth blood port 9 attached to the housing 2.

As shown in FIG. 9, when the annular elastic rib 20 is pressed together with the annular elastic body I7, a part of the annular elastic body 17 is deformed to compensate for the annular space 32. By providing two annular elastic ribs 20.30, the sealing performance between the partition wall 5 and the annular elastic body 17 is further improved. The first annular elastic rib 20 may be deformed before the second annular elastic rib 20. For this reason, the protrusion height of the second annular elastic rib 30 is higher than that of the first annular elastic rib 20. Slightly, specifically, 0.2
The culm degree may be lower by ~0.5 mrtt. Further, like the first annular elastic rib 20, the second annular elastic rib 30 also has a diameter that increases toward the inner side surface or the tip, and becomes thinner toward the tip, in order to make it easy to deform. It's good that it is. The height of the second annular elastic rib 30 is preferably about 0.3 to 2.0 mm, and if the thickness is thinner toward the tip as shown in FIG. , 10 to 25 mm, and the width at the tip is preferably about 0 to 1.5 Ri.

A blood inflow chamber and a blood outflow chamber are formed between the blood port 9 and the partition wall 5, respectively.

Then, by attaching the blood port 9 formed by integrally molding the annular elastic body 17 as described above to the housing,
The annular elastic body 17 is pressed against the annular elastic rib 20 or the annular rib 22 of the blood port 9 and the periphery of the partition wall 5, that is, the periphery of the partition wall where no hollow fiber membrane bundle is present, thereby providing good sealing performance. It is maintained.

As a method for integrally molding the annular elastic body 17 on the blood bow 1-9, for example, by two-color injection molding, the blood port is first injection molded, and then the annular elastic body 17 is continuously fixed to the annular recess of the blood port. There is a method of injection molding an annular elastic body.

Another method is to first place or inject the annular elastic body into an injection mold, and then mold the blood port resin by injection molding, insert molding, or two-color molding. I can think of a way to mold it. In the two-color injection molding method described above, bulges may occur near the apex of 42 in FIG. It is covered by an annular elastic body.

In insert molding, whether the synthetic resin forming the blood port 9.10 and the elastic body 17.18 are melt-bonded to each other, or whether the annular elastic body 17.18 or the annular recess as shown in FIG. It is preferable to have a structure that prevents it from coming off easily.

As the material for the blood port 9, thermoplastic resins such as polypropylene, polyolefins such as polyethylene, polycarbonate, acrylonitrile-styrene copolymer, butane-styrene copolymer, polystyrene, etc. are preferably used. The annular elastic body 17 is preferably made of polyolefin elastomer, vulcanized comb, isoprene comb, butane comb, ethylene-propylene comb, styrene-based elastomer (e.g., styrene-butane-styrene flock copolymer), or the like. used for.

When a two-color molding method is used as a molding method for the annular elastic body 17, it is preferable to use a material that is compatible or adhesive with the material of the flow path forming member. For example, if the blood port 9 is made of polyolefin, it is preferable to use polyolefin elastomer. but,
In the case of the blood port 9 having the shape shown in FIG. 3, since it has the protrusion 36, the resin forming the blood port 9 and the resin forming the annular elastic body 17 are compatible or adhesive. In this case, silicone comb, polyurethane, or vulcanized comb may be used as the elastic body molding resin. In particular, by using room-temperature curing type 7Ribuncom polyurethane as the elastic body molding resin,
Injection molding of the elastic body can be performed at almost room temperature, so when the resin for molding the elastic body is injected, the injected resin is not at high temperature, so the molded blood port may be deformed, especially.
This is preferable because it does not cause deformation or molten state on the contact surface with the injected resin. In addition, when insert molding is used, isoprene comb, ethylene-propylene comb, /
It is preferable to use an elastomer such as silicon comb.

The hollow fiber membrane type artificial dialyzer 1 is then sterilized before use. For sterilization, known methods such as ethylene oxide gas sterilization and autoclave sterilization are used. When performing autoclave sterilization, add a liquid (e.g., physiological saline,
Sterilization is performed by autoclaving with the openings (dialysate inlet and outlet [-'', blood inlet and outlet) sealed with an elastic member.

The blood processing apparatus of the present invention has been described using an example in which the blood processing apparatus of the present invention is applied to an artificial dialysis machine, but the blood processing apparatus of the present invention can also be applied to an artificial lung, a plasma separator, and the like.

[Effects of the Invention] The hollow fiber membrane type liquid treatment device of the present invention comprises a hollow fiber membrane bundle consisting of a haw/fugu, a large number of hollow fiber membranes for blood processing inserted into the haunong, and a hollow fiber membrane bundle consisting of a haw/fugu and a large number of hollow fiber membranes for blood treatment inserted in the haunong, and the vicinity of both ends of the haunong. an inlet and an outlet for a blood processing fluid provided in each;
a partition wall that fixes both ends of the hollow fiber membrane bundle to both ends of the hanging; a blood inflow side liquid port having a blood inlet port attached to the end of one partition wall; and a blood inflow side liquid port attached to the end of the other partition wall. and a blood outflow side blood port having a blood outflow port, the two blood ports each having an annular recess provided on the inner peripheral edge, an annular elastic body fixed to the annular recess, and a blood outflow side blood port having a blood outflow port. has an annular rib forming an inner side surface of an annular recess and an annular space formed between the annular elastic body, and the blood port is connected to the annular elastic body. Since the annular elastic body is fixed in a pressed state against the partition wall, the tension that occurs when the annular elastic body is molded first (i) and the blood port is molded by injection is due to the tension of the annular elastic body in the annular space. On the other hand, the firmness that is formed on the side surface and that occurs when the annular elastic body is molded by injection after molding the blood port is formed on the inner surface of the annular rib in the annular space. It is deformed by being pressed by the port and septum, and deforms to compensate for the annular space, so the formed bulge does not come into contact with blood during blood circulation, preventing the formation of blood clots caused by stiffness. Moreover, it also prevents it from coming off from the blood port, mixing with the blood, and flowing into the body.

[Brief explanation of drawings]

Fig. 1 is a partial sectional view of a hollow fiber membrane type liquid treatment device according to an embodiment of the present invention, and Fig. 2 is an enlarged view of a blood port used in a hollow fiber membrane type liquid treatment device according to an embodiment of the present invention. 3 is an enlarged sectional view of the annular elastic body of the blood port shown in FIG. 2, and FIG. 4 is a section showing the blood port shown in FIG. 3 attached to the housing. The enlarged sectional view, FIG. S, is an explanatory diagram for molding the blood port shown in FIG. 3, and FIG.
FIG. 7 is an enlarged sectional view of the vicinity of the annular elastic body of a blood port of another example, FIG. 8 is a partially enlarged sectional view showing the blood port shown in FIG. 7 attached to a housing, and FIG. 9 is an enlarged cross-sectional view of the vicinity of the annular elastic body of another example of the blood port,
FIG. 10 is an enlarged sectional view of a blood port used in a conventional hollow fiber membrane type liquid treatment device. DESCRIPTION OF SYMBOLS 1... Hollow fiber membrane type liquid treatment device, 2... Hau, Ng, 3... Hollow fiber membrane, 5.6
... septum, 9.10 ... blood port, 17,
18... Annular elastic body, 20... Annular elastic rib, 22... Annular rib, 23.
... Attachment part, 24...6 part, 26... Annular recess, 30... Second annular arch neutral rib, 32... Annular space, 36... Projection part, Fig. 2 Figure 1 Figure 3 Figure 9 Figure 10

Claims (9)

[Claims] (1) A housing, a hollow fiber membrane bundle consisting of a large number of hollow fiber membranes for blood treatment inserted into the housing, and an inlet and an outlet for blood treatment fluid provided near both ends of the housing, respectively. , a partition that fixes both ends of the hollow fiber membrane bundle to both ends of the housing, a blood inflow side blood port having a blood inlet attached to an end of one partition, and an end of the other partition wall. a blood outflow side blood port having an attached blood outflow port, the two blood ports each having an annular recess provided in an inner peripheral edge;
The blood port has an annular elastic body fixed to the annular recess, and an annular space formed between the annular rib and the annular elastic body forming an inner side surface of the annular recess of the blood port. The hollow fiber membrane type blood processing device is characterized in that the annular elastic body is fixed to the housing in a state where it is pressed against the partition wall. (2) The hollow fiber membrane type blood processing device according to claim 1, wherein the annular elastic body is deformed by pressure to compensate for the annular space. (3) the annular elastic body has an annular elastic rib in a portion projecting outward from the annular recess of the blood port;
3. The hollow fiber membrane type blood processing device according to claim 1, wherein the annular elastic rib is compressed between an annular rib forming an inner side surface of the annular recess of the blood port and the partition wall. (4) The annular elastic rib protrudes from the central portion of the annular elastic body, and the outer side surface of the annular elastic rib has a diameter that decreases toward the tip. The hollow fiber membrane type blood processing device according to any one of claims 1 to 3, which has a thin wall. (5) The annular elastic body has a first annular rib that protrudes from a center side portion of the annular elastic body and is pressed between the partition wall and an annular rib that forms an inner side surface of the annular recess of the blood port. An elastic rib, a shoulder portion that protrudes from the outer side of the annular elastic body and forms an outer side surface of the annular recess of the blood port, and a second annular elastic rib that is pressed between the partition wall. The hollow fiber membrane type blood processing device according to any one of claims 1 to 4. (6) The hollow fiber membrane type blood processing device according to claim 5, wherein the second annular elastic rib has an inner side surface that increases in diameter toward the tip and becomes thinner toward the tip. (7) The partition wall has a peripheral edge where no hollow fibers are present, and the annular elastic rib of the annular elastic body is in contact with the peripheral edge where no hollow fibers are present. 6. The hollow fiber membrane type blood processing device according to any one of 6. (8) The hollow fiber membrane type blood processing device according to any one of claims 1 to 7, wherein the hollow fiber membrane type blood processing device is a hollow fiber membrane type dialysis device. (9) The hollow fiber membrane type blood processing device according to any one of claims 1 to 8, wherein the annular elastic body is integrally molded by a two-color molding method.