JPH04501055A - 細胞のｈｉｖ―ウイルスによる感染を阻止するためのモノクローナル抗体 - Google Patents

細胞のｈｉｖ―ウイルスによる感染を阻止するためのモノクローナル抗体

Info

Publication number
JPH04501055A
JPH04501055A JP1508890A JP50889089A JPH04501055A JP H04501055 A JPH04501055 A JP H04501055A JP 1508890 A JP1508890 A JP 1508890A JP 50889089 A JP50889089 A JP 50889089A JP H04501055 A JPH04501055 A JP H04501055A
Authority
JP
Japan
Prior art keywords
cells
virus
infection
antibody
hiv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1508890A
Other languages
English (en)
Japanese (ja)
Inventor
エムリッヒ，フランク
フンスマン，ゲルハルト
リューケ，ヴォルフガング
Original Assignee
マックス―プランク―ゲゼルシャフト　ツール　フェルデルング　デル　ヴィッセンシャフテン　エー　ファウ
ドイッチェス　プリマテンツェントルム　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マックス―プランク―ゲゼルシャフト　ツール　フェルデルング　デル　ヴィッセンシャフテン　エー　ファウ, ドイッチェス　プリマテンツェントルム　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング filed Critical マックス―プランク―ゲゼルシャフト　ツール　フェルデルング　デル　ヴィッセンシャフテン　エー　ファウ
Publication of JPH04501055A publication Critical patent/JPH04501055A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP1508890A 1988-08-23 1989-08-22 細胞のｈｉｖ―ウイルスによる感染を阻止するためのモノクローナル抗体 Pending JPH04501055A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3828582.7 1988-08-23
DE3828582A DE3828582A1 (de) 1988-08-23 1988-08-23 Monoklonaler antikoerper zur inhibierung der infektion von zellen durch hiv-viren

Publications (1)

Publication Number Publication Date
JPH04501055A true JPH04501055A (ja) 1992-02-27

Family

ID=6361424

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1508890A Pending JPH04501055A (ja) 1988-08-23 1989-08-22 細胞のｈｉｖ―ウイルスによる感染を阻止するためのモノクローナル抗体

Country Status (7)

Country Link
EP (1) EP0430999A1 (da)
JP (1) JPH04501055A (da)
AU (1) AU629847B2 (da)
DE (1) DE3828582A1 (da)
DK (1) DK24891A (da)
ES (1) ES2018387A6 (da)
WO (1) WO1990002199A1 (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017039732A (ja) * 2010-12-02 2017-02-23 フラウンホーファー−ゲゼルシャフト ツール フエルデルング デア アンゲヴァンテン フォルシュング エー．ファオ． 特に移植片対宿主病（ＧｖＨＤ）を予防するための抗ＣＤ４抗体

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3919294C2 (de) * 1989-06-13 1998-04-23 Frank Prof Dr Emmrich Verwendung eines monoklonalen Antikörpers zur Behandlung einer Autoimmunerkrankung
US5961976A (en) * 1996-06-03 1999-10-05 United Biomedical, Inc. Antibodies against a host cell antigen complex for pre- and post-exposure protection from infection by HIV
SG11201702056YA (en) 2014-09-16 2017-04-27 United Biomedical Inc Treatment and functional cure of hiv infection by monoclonal antibodies to cd4 mediating competitive hiv entry inhibition
CA3033728A1 (en) 2016-08-13 2018-02-22 Ubi Ip Holdings Treatment and sustained virologic remission of hiv infection by antibodies to cd4 in haart stabilized patients

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683295A (en) * 1984-05-24 1987-07-28 Scripps Clinic And Research Foundation Method for the preparation of anti-receptor antibodies
FR2570278B1 (fr) * 1984-09-14 1987-02-13 Pasteur Institut Compositions et procede pour proteger les lymphocytes t contre l'agent etiologique des lymphadenopathies et du syndrome d'immunodepression acquise
JP3134874B2 (ja) * 1986-08-21 2001-02-13 ザ・トラステイーズ・オブ・コロンビア・ユニヴアーシテイ・イン・ザ・シテイ・オブ・ニユー・ヨーク Ｔ細胞表面タンパク質ｔ４をコードするｄｎａ並びにｔ４フラグメントのａｉｄｓ治療への使用
FI891226L (fi) * 1988-04-28 1989-10-29 Univ Leland Stanford Junior Reseptordeterminanter i anti-t-celler foer behandling av autoimmunsjukdom.
EP0380018B1 (en) * 1989-01-23 1995-07-19 Abbott Laboratories Rat monoclonal antibodies directed against human antigens and processes for preparation thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017039732A (ja) * 2010-12-02 2017-02-23 フラウンホーファー−ゲゼルシャフト ツール フエルデルング デア アンゲヴァンテン フォルシュング エー．ファオ． 特に移植片対宿主病（ＧｖＨＤ）を予防するための抗ＣＤ４抗体
US10227564B2 (en) 2010-12-02 2019-03-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anti CD4 antibodies to prevent in particular graft-versus-host-disease (GvHD)

Also Published As

Publication number Publication date
DK24891D0 (da) 1991-02-13
DK24891A (da) 1991-02-13
WO1990002199A1 (de) 1990-03-08
AU4070289A (en) 1990-03-23
AU629847B2 (en) 1992-10-15
DE3828582A1 (de) 1990-03-01
ES2018387A6 (es) 1991-04-01
EP0430999A1 (de) 1991-06-12

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