JPH04501357A - フラジルｘ症候群を検出するためのプローブ - Google Patents

フラジルｘ症候群を検出するためのプローブ

Info

Publication number
JPH04501357A
JPH04501357A JP1511190A JP51119089A JPH04501357A JP H04501357 A JPH04501357 A JP H04501357A JP 1511190 A JP1511190 A JP 1511190A JP 51119089 A JP51119089 A JP 51119089A JP H04501357 A JPH04501357 A JP H04501357A
Authority
JP
Japan
Prior art keywords
dna
flagyl
iai
human
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1511190A
Other languages
English (en)
Japanese (ja)
Inventor
デイヴィース，ケイ，エリザベス
ベル，マーティン
パターソン，マーク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Research Council filed Critical Medical Research Council
Publication of JPH04501357A publication Critical patent/JPH04501357A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP1511190A 1988-11-01 1989-11-01 フラジルｘ症候群を検出するためのプローブ Pending JPH04501357A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888825530A GB8825530D0 (en) 1988-11-01 1988-11-01 Probe
GB8825530.2 1988-11-01

Publications (1)

Publication Number Publication Date
JPH04501357A true JPH04501357A (ja) 1992-03-12

Family

ID=10646112

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1511190A Pending JPH04501357A (ja) 1988-11-01 1989-11-01 フラジルｘ症候群を検出するためのプローブ

Country Status (5)

Country Link
EP (1) EP0441821A1 (fr)
JP (1) JPH04501357A (fr)
AU (1) AU4487189A (fr)
GB (1) GB8825530D0 (fr)
WO (1) WO1990005194A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8928029D0 (en) * 1989-12-12 1990-02-14 Medical Res Council Probe
EP0724646B1 (fr) * 1991-01-04 2001-06-27 Washington University Sequences d'adn associees au syndrome de chromosome x fragile isole
FR2672618B1 (fr) * 1991-02-13 1994-12-02 Centre Nat Rech Scient Fragment d'acide nucleique de la region du chromosome x implique dans le syndrome x fragile, sonde nucleotidique et procede pour le diagnostic du retard mental avec x fragile.
WO1992014840A1 (fr) * 1991-02-13 1992-09-03 Institut National De La Sante Et De La Recherche Medicale Fragment d'acide nucleique de la region du chromosome x implique dans le syndrome x fragile, sonde nucleotidique et procede pour le diagnostic du retard mental avec x fragile
US6180337B1 (en) * 1991-05-24 2001-01-30 Baylor College Of Medicine Diagnosis of the fragile X syndrome
US5876949A (en) * 1995-05-31 1999-03-02 The Trustees Of The University Of Pennsylvania Antibodies specific for fragile X related proteins and method of using the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8627123D0 (en) * 1986-11-13 1986-12-10 Amersham Int Plc Dna sequence

Also Published As

Publication number Publication date
EP0441821A1 (fr) 1991-08-21
AU4487189A (en) 1990-05-28
GB8825530D0 (en) 1988-12-07
WO1990005194A1 (fr) 1990-05-17

Similar Documents

Publication Publication Date Title
Carrier et al. Mapping of a novel gene for familial hypertrophic cardiomyopathy to chromosome 11
Severini et al. A new locus for arrhythmogenic right ventricular dysplasia on the long arm of chromosome 14
Barton et al. The myosin alkali light chains of mouse ventricular and slow skeletal muscle are indistinguishable and are encoded by the same gene.
Bhattacharya et al. Close genetic linkage between X-linked retinitis pigmentosa and a restriction fragment length polymorphism identified by recombinant DNA probe L1. 28
JP2750228B2 (ja) 遺伝的特性決定用ポリヌクレオチド
Pereira et al. Novel viruses in human faeces
Ranum et al. Localization of the autosomal dominant HLA-linked spinocerebellar ataxia (SCA1) locus, in two kindreds, within an 8-cM subregion of chromosome 6p
Georges et al. Characterization of a set of variable number of tandem repeat markers conserved in Bovidae
US5654148A (en) Multicolor in situ hybridization methods for genetic testing
Flomen et al. Construction and Analysis of a Sequence-Ready Map in 4q25: Rieger Syndrome Can Be Caused by Haploinsufficiency ofRIEG, but Also by Chromosome Breaks≈ 90 kb Upstream of This Gene
Rich et al. Spinocerebellar ataxia: localization of an autosomal dominant locus between two markers on human chromosome 6
Wainscoat et al. The molecular basis for the clinical diversity of β thalassaemia in Cypriots
Darras et al. Normal human genomic restriction-fragment patterns and polymorphisms revealed by hybridization with the entire dystrophin cDNA
US5498521A (en) Diagnosis of hereditary retinal degenerative diseases
US5723293A (en) Diagnostic method and kit for determining Rh blood group genotype
EP0724646A4 (fr) Sequences d'adn associees au syndrome de chromosome x fragile isole
Overhauser et al. Identification of 28 DNA fragments that detect RFLPs in 13 distinct physical regions of the short arm of chromosome 5
JP4130125B2 (ja) 牛における複合脊椎奇形キャリアーを同定するための遺伝試験
US5262529A (en) Diagnosis of hereditary retinal degenerative diseases
EP0441821A1 (fr) Sonde permettant de detecter la presence d'un syndrome x fragile
Wakui et al. Familial 14-Mb deletion at 21q11. 2–q21. 3 and variable phenotypic expression
Bettecken et al. Identification of a 220-kb insertion into the Duchenne gene in a family with an atypical course of muscular dystrophy
Diehl et al. A refined genetic map of the region of chromosome 17 surrounding the von Recklinghausen neurofibromatosis (NF1) gene
DE69225797T2 (de) Nukleinsäure fragment des x-chromosomen bereichs beteiligt am empfindlichen x-syndrom, nukleotidische sonde und verfahren für die diagnose von geistiger zurückgebliebenheit mit empfindlichem x
Connor et al. Application of an intragenic genomic probe to genetic counselling for haemophilia B in the west of Scotland.