JPH0466208B2 - - Google Patents

Info

Publication number: JPH0466208B2
Authority: JP; Japan
Prior art keywords: constipation; phytosterol; phytosterols; intestinal; sterol
Prior art date: 1984-08-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP17364084A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6150919A (ja

Inventor

Akira Kitano

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

TENKOSHA KK

Original Assignee

TENKOSHA KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-20

Filing date

1984-08-20

Publication date

1992-10-22

1984-08-20 Application filed by TENKOSHA KK filed Critical TENKOSHA KK

1984-08-20 Priority to JP17364084A priority Critical patent/JPS6150919A/ja

1986-03-13 Publication of JPS6150919A publication Critical patent/JPS6150919A/ja

1992-10-22 Publication of JPH0466208B2 publication Critical patent/JPH0466208B2/ja

Status Granted legal-status Critical Current

Links

206010010774 Constipation Diseases 0.000 claims description 18
OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 claims description 8
LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 claims description 8
NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 claims description 8
KZJWDPNRJALLNS-VPUBHVLGSA-N (-)-beta-Sitosterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@@H](C(C)C)CC)C)CC4)CC3)CC=2)CC1 KZJWDPNRJALLNS-VPUBHVLGSA-N 0.000 claims description 4
CSVWWLUMXNHWSU-UHFFFAOYSA-N (22E)-(24xi)-24-ethyl-5alpha-cholest-22-en-3beta-ol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 CSVWWLUMXNHWSU-UHFFFAOYSA-N 0.000 claims description 4
KLEXDBGYSOIREE-UHFFFAOYSA-N 24xi-n-propylcholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CCC)C(C)C)C1(C)CC2 KLEXDBGYSOIREE-UHFFFAOYSA-N 0.000 claims description 4
OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 claims description 4
OILXMJHPFNGGTO-NRHJOKMGSA-N Brassicasterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@](C)([C@H]([C@@H](/C=C/[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 OILXMJHPFNGGTO-NRHJOKMGSA-N 0.000 claims description 4
SGNBVLSWZMBQTH-FGAXOLDCSA-N Campesterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 SGNBVLSWZMBQTH-FGAXOLDCSA-N 0.000 claims description 4
LPZCCMIISIBREI-MTFRKTCUSA-N Citrostadienol Natural products CC=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4[C@H](C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C LPZCCMIISIBREI-MTFRKTCUSA-N 0.000 claims description 4
ARVGMISWLZPBCH-UHFFFAOYSA-N Dehydro-beta-sitosterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CC=C21 ARVGMISWLZPBCH-UHFFFAOYSA-N 0.000 claims description 4
BTEISVKTSQLKST-UHFFFAOYSA-N Haliclonasterol Natural products CC(C=CC(C)C(C)(C)C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C BTEISVKTSQLKST-UHFFFAOYSA-N 0.000 claims description 4
OILXMJHPFNGGTO-ZRUUVFCLSA-N UNPD197407 Natural products C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)C=C[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZRUUVFCLSA-N 0.000 claims description 4
HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 claims description 4
MJVXAPPOFPTTCA-UHFFFAOYSA-N beta-Sistosterol Natural products CCC(CCC(C)C1CCC2C3CC=C4C(C)C(O)CCC4(C)C3CCC12C)C(C)C MJVXAPPOFPTTCA-UHFFFAOYSA-N 0.000 claims description 4
NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 claims description 4
235000004420 brassicasterol Nutrition 0.000 claims description 4
OILXMJHPFNGGTO-ZAUYPBDWSA-N brassicasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZAUYPBDWSA-N 0.000 claims description 4
235000000431 campesterol Nutrition 0.000 claims description 4
SGNBVLSWZMBQTH-PODYLUTMSA-N campesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]1(C)CC2 SGNBVLSWZMBQTH-PODYLUTMSA-N 0.000 claims description 4
239000000203 mixture Substances 0.000 claims description 4
235000015500 sitosterol Nutrition 0.000 claims description 4
KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 claims description 4
229950005143 sitosterol Drugs 0.000 claims description 4
HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 claims description 4
235000016831 stigmasterol Nutrition 0.000 claims description 4
229940032091 stigmasterol Drugs 0.000 claims description 4
BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 claims description 4
241001465754 Metazoa Species 0.000 claims description 3
239000000470 constituent Substances 0.000 claims description 3
229930182558 Sterol Natural products 0.000 description 7
150000003432 sterols Chemical class 0.000 description 7
235000003702 sterols Nutrition 0.000 description 7
229940079593 drug Drugs 0.000 description 6
239000003814 drug Substances 0.000 description 6
229940068065 phytosterols Drugs 0.000 description 6
244000068988 Glycine max Species 0.000 description 5
235000010469 Glycine max Nutrition 0.000 description 5
239000003795 chemical substances by application Substances 0.000 description 4
230000013872 defecation Effects 0.000 description 4
230000000694 effects Effects 0.000 description 4
239000000284 extract Substances 0.000 description 4
230000000968 intestinal effect Effects 0.000 description 4
239000003921 oil Substances 0.000 description 4
241000196324 Embryophyta Species 0.000 description 3
235000013305 food Nutrition 0.000 description 3
210000002429 large intestine Anatomy 0.000 description 3
239000008141 laxative Substances 0.000 description 3
240000002791 Brassica napus Species 0.000 description 2
235000004977 Brassica sinapistrum Nutrition 0.000 description 2
241000282412 Homo Species 0.000 description 2
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
230000001684 chronic effect Effects 0.000 description 2
229940000425 combination drug Drugs 0.000 description 2
210000001035 gastrointestinal tract Anatomy 0.000 description 2
239000004615 ingredient Substances 0.000 description 2
239000008101 lactose Substances 0.000 description 2
229940125722 laxative agent Drugs 0.000 description 2
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
238000000034 method Methods 0.000 description 2
235000002378 plant sterols Nutrition 0.000 description 2
230000011514 reflex Effects 0.000 description 2
-1 steroid alcohols Chemical class 0.000 description 2
239000008143 stimulant laxative Substances 0.000 description 2
241001474374 Blennius Species 0.000 description 1
241000282472 Canis lupus familiaris Species 0.000 description 1
229920002261 Corn starch Polymers 0.000 description 1
206010059866 Drug resistance Diseases 0.000 description 1
208000036115 Faecal volume increased Diseases 0.000 description 1
206010056325 Faecaloma Diseases 0.000 description 1
208000008415 Fecal Impaction Diseases 0.000 description 1
241000282326 Felis catus Species 0.000 description 1
241000233866 Fungi Species 0.000 description 1
206010020751 Hypersensitivity Diseases 0.000 description 1
206010049816 Muscle tightness Diseases 0.000 description 1
240000007594 Oryza sativa Species 0.000 description 1
235000007164 Oryza sativa Nutrition 0.000 description 1
229920002472 Starch Polymers 0.000 description 1
210000003815 abdominal wall Anatomy 0.000 description 1
230000033228 biological regulation Effects 0.000 description 1
239000008142 bulk forming laxative Substances 0.000 description 1
239000004067 bulking agent Substances 0.000 description 1
229940084030 carboxymethylcellulose calcium Drugs 0.000 description 1
239000001913 cellulose Substances 0.000 description 1
229920002678 cellulose Polymers 0.000 description 1
235000012000 cholesterol Nutrition 0.000 description 1
230000008602 contraction Effects 0.000 description 1
239000008120 corn starch Substances 0.000 description 1
239000002537 cosmetic Substances 0.000 description 1
239000010779 crude oil Substances 0.000 description 1
230000002354 daily effect Effects 0.000 description 1
230000001877 deodorizing effect Effects 0.000 description 1
235000005911 diet Nutrition 0.000 description 1
230000037213 diet Effects 0.000 description 1
235000014113 dietary fatty acids Nutrition 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
239000008157 edible vegetable oil Substances 0.000 description 1
230000003203 everyday effect Effects 0.000 description 1
239000003925 fat Substances 0.000 description 1
239000000194 fatty acid Substances 0.000 description 1
229930195729 fatty acid Natural products 0.000 description 1
230000003636 fecal output Effects 0.000 description 1
235000021197 fiber intake Nutrition 0.000 description 1
239000000796 flavoring agent Substances 0.000 description 1
235000013355 food flavoring agent Nutrition 0.000 description 1
235000011389 fruit/vegetable juice Nutrition 0.000 description 1
230000002496 gastric effect Effects 0.000 description 1
229930182470 glycoside Natural products 0.000 description 1
150000002338 glycosides Chemical class 0.000 description 1
238000011835 investigation Methods 0.000 description 1
230000002475 laxative effect Effects 0.000 description 1
150000002632 lipids Chemical class 0.000 description 1
230000007774 longterm Effects 0.000 description 1
235000019359 magnesium stearate Nutrition 0.000 description 1
235000012054 meals Nutrition 0.000 description 1
235000013372 meat Nutrition 0.000 description 1
230000002503 metabolic effect Effects 0.000 description 1
230000007659 motor function Effects 0.000 description 1
210000003205 muscle Anatomy 0.000 description 1
229930014626 natural product Natural products 0.000 description 1
235000008935 nutritious Nutrition 0.000 description 1
239000000843 powder Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000003825 pressing Methods 0.000 description 1
210000000664 rectum Anatomy 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
235000009566 rice Nutrition 0.000 description 1
210000002027 skeletal muscle Anatomy 0.000 description 1
210000002460 smooth muscle Anatomy 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000000126 substance Substances 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP17364084A 1984-08-20 1984-08-20 人間及び動物用の便秘解消剤 Granted JPS6150919A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP17364084A JPS6150919A (ja)	1984-08-20	1984-08-20	人間及び動物用の便秘解消剤

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP17364084A JPS6150919A (ja)	1984-08-20	1984-08-20	人間及び動物用の便秘解消剤

Publications (2)

Publication Number	Publication Date
JPS6150919A JPS6150919A (ja)	1986-03-13
JPH0466208B2 true JPH0466208B2 (2)	1992-10-22

Family

ID=15964353

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP17364084A Granted JPS6150919A (ja)	1984-08-20	1984-08-20	人間及び動物用の便秘解消剤

Country Status (1)

Country	Link
JP (1)	JPS6150919A (2)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6972195B2 (en)	2002-09-27	2005-12-06	Rongxiang Xu	Composition and method for culturing potentially regenerative cells and functional tissue-organs in vitro
US6685971B2 (en) *	2001-06-28	2004-02-03	Rongxiang Xu	Method and composition for repairing and promoting regeneration of mucosal tissue in the gastrointestinal tract
CN1827766B (zh)	2001-06-28	2010-08-25	徐荣祥	体外细胞的培养方法
EP1737537A1 (en) *	2004-04-13	2007-01-03	Boehringer Ingelheim International GmbH	Use of simethicone in constipated patients

1984
- 1984-08-20 JP JP17364084A patent/JPS6150919A/ja active Granted

Also Published As

Publication number	Publication date
JPS6150919A (ja)	1986-03-13

Legal Events

Date	Code	Title	Description
2004-08-20	EXPY	Cancellation because of completion of term

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