JPH0466514A - Cosmetic - Google Patents

Abstract

PURPOSE:To obtain a cosmetic capable of imparting a skin with excellent moisturizing effect and emollient effect, suppressing tyrosinase activity and exhibiting general cosmetic effect such as humectant effect and skin-beautifying effect by compounding an extract obtained from a gastropod. CONSTITUTION:A gastropod such as spiny top shell, Japanese abalone and sea slug (excluding the guts) is cut into small pieces, immersed in a solvent such as water or ethanol and extracted by warming at 30-70 deg.C. The extract is used as an active component and properly compounded with conventional cosmetic components such as vehicle, perfume, oil and fat, surfactant, humectant, pH-conditioner, thickener, antioxidant and UV absorber to obtain the objective cosmetic. The amount of the extract is 0.01-90pts.wt. (in terms of solid) based on 100pts.wt. of the cosmetic. It can be used in the form of cream, lotion, milky lotion, face lotion, pack, lipstick, foundation, body soap, soap, bathing agent, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to cosmetics. More specifically, the present invention relates to cosmetics that can be suitably used in basic cosmetics, make-up cosmetics, hair cosmetics, bath additives, and the like.

[Conventional technology] The development of cosmetics that provide excellent moisturizing and emollient effects to the skin, suppress tyrosinase activity, and provide comprehensive cosmetic effects such as moisturizing and whitening have long been awaited. .

Therefore, as a cosmetic that is easily absorbed through the skin and activates skin metabolism by supplying physiologically active substances to the skin, JP-A-59-110608 and JP-A-5
A cosmetic described in Japanese Patent No. 9-95210 has been proposed.

However, although all of the cosmetics described in these publications do have the effect of activating skin metabolism, they do not suppress tyrosinase activity and sufficiently exhibit moisturizing and whitening effects at the same time. It's not something you do.

[Problem to be solved by the invention i] Therefore, in view of the above-mentioned prior art, the present inventors have provided the skin with an excellent moisturizing effect and emollient effect that is effective for stains and freckles, suppressing the activity of tyrosinase, and providing a moisturizing effect. As a result of intensive research aimed at developing cosmetics that have both effective and whitening effects, surprisingly,
Extracts from gastropods (excluding internal organs) are
All of these effects are exhibited at the same time [2] Furthermore, it was discovered that such an extract exhibits a hair protection effect and a heat-retaining effect as a bath additive.1-1 The present invention was completed.

[Means for Solving the Problems] In other words, the present invention relates to a cosmetic containing an extract obtained from gastropods (excluding snails and internal organs).

[Operations and Examples] Although the components in the extract obtained from gastropods (excluding snails and internal organs) used in the present invention are not yet clear, according to the research of the present inventors, the extract It has been confirmed that these substances contain water-soluble proteins. It is believed that these various components exert the cosmetic effects aimed at in the present invention.

Examples of gastropods (excluding snails and internal organs) used in the present invention include abalones, turban shells, tokobushi, claw snails, snails, snails, Aplysia snails, laminas, snails, snails, and slugs. The examples are not limited to examples only.

Extracts obtained from gastropods (excluding internal organs) used in the present invention include, for example, fresh salmon gastropods (excluding internal organs) and gastropods frozen in fresh salmon state (excluding internal organs). Extract obtained by immersing and extracting (except for Examples include granules□ and particulate matter,
The present invention is not limited by the form of such extracts.

There are various methods to prepare the extract, but one example is to cut a gastropod (excluding internal organs) into thin pieces, immerse it in an extraction solvent described below, The present invention is not limited to such methods, but may include methods such as heating I and extraction from scratch.

Examples of the extraction solvent include water; aqueous sodium citrate solution; lower alcohols such as methanol and ethanol; polyols such as ethylene glycol, propylene glycol, glycerin, and 13-butylene glycol, oleyl alcohol, stearyl alcohol, and octyl alcohol. Higher alcohols such as dodecanol.

Examples include ketones such as acetone; esters with ethyl acetate; hydrocarbon solvents such as hexane, dichloromethane, benzene, toluene, and ethers; these may be used alone or in combination of two or more. Among these, water and water-soluble solvents are preferred from the viewpoint of wide application to cosmetics, and water, ethanol, glycerin, and 1,3-butylene glycol are particularly preferred.

In the present invention, during extraction, for example, proteolytic enzymes such as trypsin, pepsin, actinase, glycylglycine bebutitase, carboxypebutidase, aminobebutitase, papain, promelain, chymopapain, and chymotrypsin are used. It is preferable that the extract is subjected to a treatment in order to further exhibit the effect of suppressing the activity of tyrosinase. The amount of the protease used is 100 parts of the gastropod (excluding internal organs).
It is preferably 10 to 50 parts, preferably <20 to 30 parts, based on the dry weight (the same applies hereinafter). If the amount used is less than the above range, protein decomposition will be insufficient, and the effects of the extract will tend to decrease; if it exceeds the above range, adding more than the necessary amount will
It makes no sense considering the characteristics of the enzyme.

The extraction time varies depending on the type of solvent and extraction temperature, so it cannot be determined generally, but it is usually between 1 and 48
time, preferably 10 to 30 hours. In addition, since the extraction temperature varies depending on the type of solvent, etc., it cannot be determined generally, but it should be 0°C or higher, and usually 30°C or higher.
A suitable temperature is 70°C.

In addition, the pH of the obtained extract was adjusted to ensure safety for the skin.
It is preferable to adjust it to about 4 to 8.

The extract obtained in this way has an excellent moisturizing effect on human skin and an inhibitory effect on melanin production by suppressing tyrosinase activity.Furthermore, when added to hot water, it helps maintain body temperature during and after bathing. It has excellent maintenance effects.

The cosmetics of the present invention contain the above-mentioned extracts, but in addition to the extracts, they may also contain, for example, excipients and fragrances commonly used in cosmetics, oils and fats, surfactants,
Humectants, p)I regulators, thickeners, preservatives, antioxidants,
Various cosmetic ingredients such as ultraviolet absorbers, pigments, detergents, desiccants, and emulsifiers are appropriately blended.

The oils and fats include vegetable oils commonly used in cosmetics, such as liquid paraffin, paraffin, cetanol, avocado oil, olive oil, jojoba oil, and coconut oil; beef tallow, lard, horse tallow, tuttle oil, and mink oil. , parcellin oil,
Animal fats and oils such as squalane; methylpolysiloxane,
Examples include behenyl alcohol, glyceryl tricaprylcaprate, glyceryl trioctanoate, glyceryl triisopalmitate, and synthetic oils and fats such as silicone oil.

Examples of the surfactant include anionic surfactants such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and jetanolamide laurate; cationic surfactants such as stearyltrimethylammonium chloride, cetyltrimethylammonium chloride, and benzalkonium chloride; Nonionic surfactants such as glyceryl monostearate, sorbitan monostearate, polyoxyethylene sorbitan monostearate, polyoxyethylene hardened mustard oil, sucrose ester, fatty acid amide, etc. .

Examples of the moisturizer include synthetic moisturizers such as glycerin, propylene glycol, 1,3-butylene glycol, and sodium pyrrolidone carboxylate; hyaluronic acid, collagen, elastin, placenta extract, royal jelly,
Examples include natural moisturizing liquids such as microbial fermentation liquid.

Examples of the pH adjuster include sodium citrate and citric acid.

Examples of the thickener include carboxymethylcellulose, hydroxymethylcellulose, hydroxyethylcellulose, carboxyvinyl polymer polyvinyl alcohol, and gum tragacanth.

Examples of the preservative include paraoxybenzoic acid esters such as methylparaben, ethylparaben, propylparaben, and butylparaben, ethanol, and dehydroacetic acid.

Examples of the antioxidant include vitamin E1 butyloxytoluene (BIT) and butyloxyanisole (Bl(A)).

Examples of the pigment include red iron oxide, yellow iron oxide, black iron oxide, titanium oxide, nylon powder, sericite, mica, and talc.

Examples of the cleaning agent include sodium hydrogen carbonate.

Examples of the excipient include sodium sulfate.

Examples of the emulsifier include soybean lecithin oil.

The amount of each of these cosmetic ingredients varies depending on the intended use of the cosmetic, and therefore cannot be determined generally, and is preferably adjusted as appropriate depending on the intended use.

The thus obtained cosmetic of the present invention moisturizes the skin,
It has excellent properties such as preventing stains, freckles, wrinkles, etc., so it can be used for example in creams, milky lotions, etc.
Basic cosmetics such as lotions, face washes, bags, lipsticks,
It is prepared and used in the form of makeup cosmetics such as foundation, toiletry products such as body wash and soap, and bath additives.

In addition, the cosmetics of the present invention are effective for preventing split ends and hair breakage and protecting the hair by improving the environment around the hair roots and acting directly on the hair. It can be appropriately prepared into hair products such as liquid, hair blow agent, hair setting lotion, hair cream, and hair toiletry products such as shampoo conditioner and hair treatment.

The amount of the extract to be added to cosmetics varies depending on the type of cosmetic, so it cannot be determined unconditionally.
(the same applies below), the solid content of the extract is 0. [)1~
It is desirable that the amount is 90 parts, preferably 0.5 to 50 parts. If the blending amount is less than the above-mentioned range, the effect of blending the extract tends to be reduced, and if it exceeds the above-mentioned range, no further improvement in the effect can be expected.

In addition, as mentioned above, the extract and its dry powder have an excellent effect of retaining body temperature when added to hot water, so the cosmetic composition of the present invention is suitable for use as a bath additive. It is. In this way, when the cosmetic of the present invention is used as a bath agent, the amount of extract added to the cosmetic is as follows:
0.1 to 100 parts of cosmetics in terms of solid content of extract
It is desirable that the amount is 90 parts, preferably 20 to 60 parts. When using the bath additive, the amount of the bath additive used is:
It is preferable to adjust the amount of bath agent to about 5 to 25 g per 200 g of normal hot water.

Next, the cosmetic composition of the present invention will be explained in more detail based on Examples, but the present invention is not limited to these Examples.

Preparation Example 1 (Production of extract of turban shell excluding internal organs) After removing the shell and internal organs from a fresh turban shell, it is cut into thin pieces, soaked in ethyl alcohol to degrease, and dried [later, harvested]. 1 kg of the dried product was immersed in 50 g of a slightly alkaline aqueous sodium citrate solution.

Next, trypsin 2 as a proteolytic enzyme is added to this aqueous solution.
After adding 50g and extracting for about 6 hours while heating to 7.55℃, 10% lactic acid aqueous solution was added to adjust the pH to 7.0, and filtered and purified to obtain a colorless and transparent extract (solid content Approximately 4% by weight) I gained 45kg.

Preparation Example 2 (Manufacture of an extract of the part of the tokobushi excluding the internal organs) → A colorless and transparent extract was prepared in the same manner as in Preparation Example 1, except that the part of the tokobushi with the shell and internal organs removed was used instead of the tokobushi. Extract liquid (solid content & ffi: about 4 times).

Preparation Example 3 (Manufacture of extract of Aplysia Aplysia, excluding internal organs) A colorless and transparent extract was prepared in the same manner as Preparation Example 1, except that fresh Aplysia, excluding shells and internal organs, was used instead of turban shell. (Solid content: about 4% by weight) 45 kg was obtained.

Preparation Example 4 (Production of extract of abalone excluding internal organs) After removing the shell and internal organs from a fresh abalone, shred it, soak it in acetone to degrease it, and then add 1 kg of the resulting dried product. It was immersed in 50 ρ of a weakly alkaline aqueous solution containing 10% 1.3-butylene glycol. 250 g of trypsin as a proteolytic enzyme was added to this aqueous solution, and 60 g of trypsin was added as a protease.
After extraction for about 6 hours while heating to ℃, 10% aqueous phosphoric acid solution was added to adjust the pH to 6.07, and the extract was purified by filtration to produce a colorless and transparent extract (solid content: about 4% by weight). 45k
I got g.

Preparation Example 5 (Manufacture of an extract of the viscera of Lami slug) A colorless and transparent extract (solid The total weight was 45 kg (approximately 4% by weight).

Preparation Example 6 (Production of extract of snail snail excluding internal organs) A colorless and transparent extract (solid 45 kg (content about 4% by weight) was obtained.

Preparation Example 7 (Manufacture of extract of turban shell excluding internal organs) A colorless and transparent extract (solid content of about 0.5%) was prepared in the same manner as in Preparation Example 1 except that no protease was used.
1% by weight) gained about 45 kg.

Preparation Example 8 (Manufacture of Extract from the Part of Tokobushi excluding Internal Organs) A colorless and transparent extract (solid content of about 0.0%) was prepared in the same manner as in Preparation Example 2 except that no protease was used.
1% by weight) gained about 45 kg.

Preparation Example 9 (Production of Extract of Aplysia Aplysia Excluding Internal Organs) A colorless and transparent extract (solid content of about 0.00% was prepared in the same manner as in Preparation Example 3 except that no protease was used).
1% by weight) gained about 45 kg.

Preparation Example 10 (Manufacture of Extract of Abalone Excluding Internal Organs) A colorless and transparent extract (solid content of about 0.0%) was prepared in the same manner as in Preparation Example 4, except that no protease was used.
1% by weight) gained about 45 kg.

Preparation Example 11 (Manufacture of Extract of Rami Slug Excluding Internal Organs) A colorless and transparent extract (with a solid content of about 0.5%) was prepared in the same manner as in Preparation Example 5, except that no protease was used in Preparation Example 5.
1% by weight) gained about 45 kg.

Preparation Example 12 (Production of Extract of Snail Snail Excluding Internal Organs) A colorless and transparent extract (solid content of approximately 0.00% was prepared in the same manner as Preparation Example 6 except that no protease was used).
1% by weight) gained about 45 kg.

Reference Examples 1 to 13 The following tests were conducted using the extracts obtained in Preparation Examples 1 to 12 as samples.

(1) Tyrosinase activity inhibition effect (tyrosinase reaction method) Tyrosinase (2200 units) 1. Accurately weigh the oig and add phosphate buffer (pH 8,8) 2. A tyrosinase solution was prepared by dissolving in Oml.

Next, 0.8 ml of an aqueous solution obtained by diluting the extract obtained in each preparation example 10 times was weighed accurately, and 0.05% L
- 1.0 ml of tyrosine solution and phosphate buffer (pH 6)
,8) 1. Oml was added and thoroughly stirred to mix. 0.2 ml of the above tyrosinase solution was added to this solution and mixed by thorough stirring. The absorbance of this solution at a wavelength of 475 nIm was immediately measured, and then placed in a constant temperature bath at 37°C.

After 24 minutes had elapsed, this solution was taken out from the thermostatic bath, the absorbance at a wavelength of 475 nm was measured again, and the tyrosinase activity index was determined from the following formula. In addition, a blank was prepared by performing the same operation using water instead of the extract. The results are shown in Table 1.

[Tyrosinase activity index CoB (where T24 is the absorbance of the solution to which the extract was added 24 minutes after the start of the test, and B24 is the absorbance of the solution 24 minutes after the start of the test.
The absorbance of the solution in which water was added instead of the extract after a minute has elapsed, To is the absorbance of the solution in which the extract was added immediately after the start of the test, and Bo is the absorbance of the solution in which water was added instead of the extract immediately after the start of the test. Indicates the absorbance of the solution. ) Reference Examples 14 and 15 The extract obtained in Preparation Example 3 and the acid hydrolyzate of the extract were analyzed using a high-speed amino acid automatic analyzer (Newly manufactured by Hitachi, product number: L8500, for biological sample analysis). Amino acid analysis was performed. The amino acid analysis results of the extract obtained in Preparation Example 3 are shown in Table 2, and the amino acid analysis results of the acid hydrolyzate of the extract are shown in Table 3.

From the results shown in Tables 2 and 3, it can be seen that the extract obtained in Preparation Example 3 contains almost no free amino acids, and the amino acids exist in the form of bound proteins.

Margin below U Prescription Example 1 [Cream Co [Component (A)] (Part) Liquid Paraffin 9.0 Paraffin
5.0 cetanol
2.0 Glyceryl monostearate 2.0 Polyoxyethylene Sorbitan monostearate 5.0 Butylparaben 0.1 [Component (B)] Extract obtained in Preparation Example 1 30.0 Glycerin 5.0 Carboxymethyl cellulose 0.1 methylparaben
0.1 Purified water 41.4 [(
C) Ingredient fragrance
0.8 Each of the above (A) component and (B) component
After heating to 0° C. or higher, the components (A) and (B) were mixed and stirred. After cooling this to 50°C, the above (C)
The ingredients were added and further stirred and mixed to prepare a uniform ream.

Formulation example 2 [Emulsion] [Component (A)] (Part) Liquid paraffin 10.00 Jojoba oil
1.00 polyoxyethylene■
Sorbitan monostearate 2.00 Soybean lecithin oil 1.50 Methylparaben
0.15 ethylparaben
0.03 [Component (B) extract obtained in Preparation Example 3 ao, o.

Glycerin 3,001.3-Butylene glycol 2.00 Sodium carboxymethyl cellulose 0.30 Purified water
49.97 [Ingredient (C)] Fragrance 0.05 The above human ingredients and ([31 ingredients were each heated to lllO ℃, then mixed and stirred. After cooling to 50 ℃, the above fc
) ingredients were added and stirred to prepare a homogeneous emulsion.

Prescription example 3 [Lotion Co "Ingredients (Part) Ethanol 10.0 Glycerin
3.01.3-Butylene glycol
2.0 Methylparaben 0
．． 2 Citric acid 0.1 Sodium citrate 0.3 Carboxyvinyl polymer 0.1 Extract obtained in Preparation Example 2
50.0 fragrance
Micro-purified water total amount is 10
A homogeneous lotion was prepared by mixing the above components in an amount of 0.0 part.

Formulation example 4 [Back] Ingredients (Part) Polyvinyl alcohol 15.0 Hydroxymethyl cellulose 5.0 Propylene glycol
5.0 Ethanol 10.
0 Methylparaben 0.1 Preparation Example 3
The resulting extract 10.0 fragrance
micro purified water
A uniform bag was prepared by mixing and stirring the above components in amounts such that the total amount was 100.0 parts.

Formulation Example 5 [Pressed Powder] The extract obtained in Preparation Example 4 is freeze-dried by removing water with a freeze-dried powder, and this is ground by a ball mill to obtain a powder (particle size of about 30 mm or less), Powder was used.

[(A) Component] (Part) Red iron 0.5 yellow iron oxide
1.5 black iron oxide
0.1 titanium oxide 1
0.0 nylon powder 4゜0 sericite 28.0 mica
23,0 talc
25.0 Freeze-dried powder of the extract obtained in Preparation Example 4 0.7 [[B] Component] Squalane 1.0 Methylpolysiloxane 4,0 Propylparaben
0.1 dehydroacetic acid
0.1 Liquid paraffin 2.0 Fragrance Small amount The above (A) component and (B) component are mixed and stirred, and after mixing the (A) component and (B) component,
A uniform pressed powder was prepared by passing through a 200-mesh Tyler mesh sieve and pressing into a mold.

Formulation Example 6 [Shampoo] The extract obtained in Preparation Example 3 was freeze-dried in the same manner as in Formulation Example 5, and a powder obtained by pulverization (particle size of approximately 30.L)
a below) was used.

[Ingredients] (Part) Lauryl sulfate triethanolamine 15.0 Lauric acid diethanolamide
5.0 Methylvarachen
0.1 propylparaben
0.1 Freeze-dried powder of the extract obtained in Preparation Example 3 0.5 Flavor
micro purified water
A uniform shampoo was prepared by mixing and stirring the above ingredients in amounts such that the total amount was 100.0 parts.

Prescription Example 7 [Hair Set Lotion] Powder obtained by drying and powdering the extract obtained in Preparation Example 2 by spray drying (particle size: 100- or less)
was used.

[Ingredients] (Part) Gum tragacanth 2.0 Glycerin
1.0 ethanol
20.0 Methylparaben 0.2
Freeze-dried powder of extract obtained in Preparation Example 2 0.5 Flavor
micro purified water
The above ingredients were mixed and stirred in such amounts that the total amount was 100.0 parts to obtain a uniform hair setting lotion.

Formulation Example 8 [Hair Rinse] The extract obtained in Preparation Example 1 was freeze-dried in the same manner as in Formulation Example 7, and pulverized to obtain a powder (particle size of 100- or less), which was used.

[Component (A)] (Part) Behenyl alcohol 0.2 cetanol
1.5 Stearyltrimethylammonium chloride 2.0 Glyceryl monostearate (self-emulsifying type) 2.0 Hexalan (glyceryl trioctanoate, manufactured by Kyoei Kagaku Kogyo ■) 1.0 Freeze-dried powder of the extract obtained in Preparation Example 1 1.0 [Component (B)] Hydroxyethylcellulose 1.0 Methylparaben 0.2 Glycerin
3.0 Purified water 8
7.9 [(C) Component] Fragrance
0.2 Each of the above (A) component and (B) component
After heating to 0° C. or higher, the mixture was mixed and stirred. After cooling to 50℃,
Component (C) was added and further stirred and mixed to prepare a uniform hair rinse.

Formulation Example 9 [Bath Salt] The extract obtained in Preparation Example 3 was freeze-dried in the same manner as in Formulation Example 7, and the resulting powder (particle size of about 100 particles or less) was used.

[Ingredients] (Part) Sodium sulfate 47.0 Sodium hydrogen carbonate
47.0 Freeze-dried powder of the extract obtained in Preparation Example 3 6.0 Flavor
A uniform bath agent was prepared by mixing and stirring trace amounts of the above components.

Formulation Example 10 [Cream was prepared in the same manner as Formulation Example 1 except that the extract obtained in Preparation Example 7 was used instead of the extract obtained in Creamco Preparation Example 1.

Formulation Example 11 [Emulsion] A milky lotion was prepared in the same manner as in Formulation Example 2, except that the extract obtained in Preparation Example 9 was used instead of the extract obtained in Preparation Example 3.

Formulation Example 12 [Lotion] A lotion was prepared in the same manner as Formulation Example 3, except that the extract obtained in Preparation Example 8 was used instead of the extract obtained in Preparation Example 2.

Formulation Example 13 [Bag] A bag was prepared in the same manner as Formulation Example 4 except that the extract obtained in Preparation Example 9 was used instead of the extract obtained in Preparation Example 3.

Formulation Example 14 [Shampoo] A shampoo was prepared in the same manner as Formulation Example 6 except that the extract obtained in Preparation Example 10 was used instead of the extract obtained in Preparation Example 3.

Formulation Example 15 [Hair Setting Lotion] A hair setting lotion was prepared in the same manner as Formulation Example 7 except that the extract obtained in Preparation Example 11 was used instead of the extract obtained in Preparation Example 2.

Formulation Example 1B [Hair Rinse] A hair rinse was prepared in the same manner as Formulation Example 8 except that the extract obtained in Preparation Example 12 was used instead of the extract obtained in Preparation Example 11.

Comparative Prescription Example] [Cream] A cream was prepared in the same manner as Preparation Example 1 except that purified water was used instead of the extract obtained in Preparation Example 1.

Comparative Prescription Example 2 [Emulsion Co] An emulsion was prepared in the same manner as Preparation Example 2, except that purified water was used instead of the extract obtained in Preparation Example 3.

Comparative Prescription Example 3 [Lotion Co. A lotion was prepared in the same manner as Preparation Example 3 except that purified water was used instead of the extract obtained in Preparation Example 2.

Comparative Formulation Example 4 [Barafco A bag was prepared in the same manner as Formulation Example 4 except that purified water was used instead of the extract obtained in Preparation Example 3.

Comparative Formulation Example 5 [Shampoo] A shampoo was prepared in the same manner as Formulation Example 6, except that purified water was used instead of the extract obtained in Preparation Example 3.

Comparative Prescription Example 6 [Hair Set Lotion] Preparation Example 7 except that purified water was used instead of the extract obtained from Preparation Example 2.
A hair setting lotion was prepared in the same manner as above.

Comparative Prescription Example 7 "Hair Rinsco" A hair rinse was prepared in the same manner as Preparation Example 8 except that purified water was used instead of the extract obtained in Preparation Example 1.

Comparative Formulation Example 8 [Bath Agent] A bath agent was prepared in the same manner as in Formulation Example 9 (2) except that purified water was used instead of the extract obtained in Preparation Example 3.

Example 1 Prescription Examples 1-4 and 10-13 and Comparative Prescription Examples 1-
The following monitor tests were conducted on each of the cosmetics obtained in step 4. The results are shown in Table 4.

(Monitor test) The moisturizing effect, emollient effect, and skin luster when each cosmetic was applied to the skin of the face and cheeks were evaluated according to the following criteria for 100 randomly selected women aged 18 to 55. The evaluation was conducted based on the following.

[Moisture effect] A: Very moist B: Somehow moist C: Not very moist feeling compared to average E: No moist feeling at all [Emollient effect] A: Very soft and pleasant to the touch Good B: Somewhat soft and good to the touch C: Average to average Not very flexible and has a good feel E: Not at all flexible and has a poor feel [Skin gloss] A: Very shiny B: Somehow became shiny C: No change D: Somehow lost luster E: Clearly lost luster Furthermore, as a result of the monitor test, no one complained of any skin abnormality.

[Margin below] Example 2 Prescription Examples 6 to 8 and 14 to IB and Comparative Prescription Example 5 to
The hair cosmetics obtained in step 7 were subjected to the following half-head test.

The results are shown in Table 5.

(Half-head test) 20 randomly selected men between the ages of 18 and 60 used each hair cosmetic twice a day for 30 days. The street was evaluated based on the following criteria.

[Shininess] A: Very shiny B: Somehow shiny C: No change D: Somehow lost gloss E: No shiny at all [Moist feeling] A: Very moist The feeling has improved B: It has somehow become moisturized and feels better C: There has been no change D = It has not felt so moist E: It has not felt moist at all [<Exactly] A: It has improved very much. B: Somewhat improved C: No change D: Somewhat worse E: Completely worse In addition, as a result of the half-head test, no one complained of any abnormality with their hair or scalp.

[Left below] Example 3 The following monitor tests were conducted on the bath additives obtained in Formulation Example 9 and Comparative Formulation Example 8. The results are shown in Table 6.

(Monitor test) 20 randomly selected women aged 30 to 60 were given 25 g of each bath salt per 200 Il of hot water while taking a bath. The effectiveness of keeping body temperature after a 15-minute rest was evaluated based on the following criteria.

(Heat retention effect) A: Feels very warm B: Feels pleasantly warm C: Average D: Feels slightly chilly E: Chilly However, as a result of the monitor test, no one complained of any skin abnormalities. .

Table 1 [Effects of the Invention] The extract obtained from gastropods (excluding snails and internal organs) used in the present invention, especially the extract treated with proteolytic enzymes, has high moisturizing power, Moreover, since it has the effect of suppressing tyrosinase activity, the cosmetics of the present invention containing this compound exhibit excellent moisturizing and emollient effects on the skin, and provide comprehensive cosmetic effects such as moisturizing and whitening. .

Furthermore, when the cosmetic of the present invention is used as a bath agent, it has an excellent effect of keeping body temperature during and after bathing.

Furthermore, when the cosmetic of the present invention is used as a hair cosmetic, it exhibits effects such as preventing split ends and hair breakage and protecting the hair.

Claims (1)

[Claims] 1. A cosmetic containing an extract obtained from gastropods (excluding internal organs). 2. The cosmetic according to claim 1, wherein the extract has been treated with a proteolytic enzyme.