JPH0514219B2 - - Google Patents
Info
- Publication number
- JPH0514219B2 JPH0514219B2 JP63275373A JP27537388A JPH0514219B2 JP H0514219 B2 JPH0514219 B2 JP H0514219B2 JP 63275373 A JP63275373 A JP 63275373A JP 27537388 A JP27537388 A JP 27537388A JP H0514219 B2 JPH0514219 B2 JP H0514219B2
- Authority
- JP
- Japan
- Prior art keywords
- photoacoustic
- sample
- light
- excitation
- wavelength
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000005284 excitation Effects 0.000 claims description 64
- 238000004458 analytical method Methods 0.000 claims description 27
- 239000012491 analyte Substances 0.000 claims description 24
- 238000006243 chemical reaction Methods 0.000 claims description 22
- 239000000356 contaminant Substances 0.000 claims description 21
- 239000007795 chemical reaction product Substances 0.000 claims description 15
- 230000003287 optical effect Effects 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 13
- 238000010521 absorption reaction Methods 0.000 claims description 12
- 230000001678 irradiating effect Effects 0.000 claims description 10
- 230000001360 synchronised effect Effects 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 238000010895 photoacoustic effect Methods 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 230000031700 light absorption Effects 0.000 claims description 5
- 230000008105 immune reaction Effects 0.000 claims 6
- 239000000047 product Substances 0.000 claims 4
- 239000000523 sample Substances 0.000 description 35
- 238000005259 measurement Methods 0.000 description 17
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 16
- 238000012545 processing Methods 0.000 description 9
- 238000003018 immunoassay Methods 0.000 description 8
- 239000012535 impurity Substances 0.000 description 7
- 238000004445 quantitative analysis Methods 0.000 description 7
- 102100023635 Alpha-fetoprotein Human genes 0.000 description 6
- 239000003153 chemical reaction reagent Substances 0.000 description 6
- 238000001514 detection method Methods 0.000 description 6
- 239000004816 latex Substances 0.000 description 6
- 229920000126 latex Polymers 0.000 description 6
- 238000011088 calibration curve Methods 0.000 description 4
- 239000000284 extract Substances 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 3
- 238000002835 absorbance Methods 0.000 description 3
- 229940098773 bovine serum albumin Drugs 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000008363 phosphate buffer Substances 0.000 description 3
- 101000848653 Homo sapiens Tripartite motif-containing protein 26 Proteins 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 102000013529 alpha-Fetoproteins Human genes 0.000 description 2
- 108010026331 alpha-Fetoproteins Proteins 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 102000046101 human AFP Human genes 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000012488 sample solution Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 239000004793 Polystyrene Substances 0.000 description 1
- 238000000862 absorption spectrum Methods 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 238000004867 photoacoustic spectroscopy Methods 0.000 description 1
- 238000001834 photoacoustic spectrum Methods 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000013076 target substance Substances 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63275373A JPH02122243A (ja) | 1988-10-31 | 1988-10-31 | 光音響分析方法及び装置 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63275373A JPH02122243A (ja) | 1988-10-31 | 1988-10-31 | 光音響分析方法及び装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH02122243A JPH02122243A (ja) | 1990-05-09 |
| JPH0514219B2 true JPH0514219B2 (de) | 1993-02-24 |
Family
ID=17554580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63275373A Granted JPH02122243A (ja) | 1988-10-31 | 1988-10-31 | 光音響分析方法及び装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH02122243A (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3714883B2 (ja) * | 2001-03-30 | 2005-11-09 | 日立造船株式会社 | 物体の材質判別方法および材質判別装置並びに物体の選別設備 |
| JP4963482B2 (ja) * | 2008-03-18 | 2012-06-27 | 日本電信電話株式会社 | 成分濃度測定装置及び成分濃度測定方法 |
| JP6264183B2 (ja) * | 2014-05-14 | 2018-01-24 | 昭和電工株式会社 | 光音響分光方法および光音響分光装置 |
-
1988
- 1988-10-31 JP JP63275373A patent/JPH02122243A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02122243A (ja) | 1990-05-09 |
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