JPH0531423B2 - - Google Patents

Info

Publication number
JPH0531423B2
JPH0531423B2 JP59503865A JP50386584A JPH0531423B2 JP H0531423 B2 JPH0531423 B2 JP H0531423B2 JP 59503865 A JP59503865 A JP 59503865A JP 50386584 A JP50386584 A JP 50386584A JP H0531423 B2 JPH0531423 B2 JP H0531423B2
Authority
JP
Japan
Prior art keywords
pump
blood
heart
rotor
small
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP59503865A
Other languages
English (en)
Other versions
JPS61500059A (ja
Inventor
Richaado Kei Wanpuraa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIMUBASU Inc
Original Assignee
NIMUBASU Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIMUBASU Inc filed Critical NIMUBASU Inc
Publication of JPS61500059A publication Critical patent/JPS61500059A/ja
Publication of JPH0531423B2 publication Critical patent/JPH0531423B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/827—Sealings between moving parts
    • A61M60/829—Sealings between moving parts having a purge fluid supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/405—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/13—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/408—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
    • A61M60/411—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
    • A61M60/414—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/804—Impellers
    • A61M60/806—Vanes or blades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818—Bearings
    • A61M60/825—Contact bearings, e.g. ball-and-cup or pivot bearings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/871—Energy supply devices; Converters therefor
    • A61M60/88—Percutaneous cables
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818—Bearings
    • A61M60/824—Hydrodynamic or fluid film bearings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/03—Heart-lung
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S415/00—Rotary kinetic fluid motors or pumps
    • Y10S415/90—Rotary blood pump

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • External Artificial Organs (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)

Description

請求の範囲 １ ａ 両端部が開放しており、人間の血管に通
すことのできる形状および大きさを有している
細長形のハウジングと； ｂ 前記ハウジングを経て長手方向に血液を送り
出す前記ハウジング内の回転ポンプ手段と； ｃ 前記ハウジングから延在し、かつ前記血液内
に該血管を閉塞することなく入れられる導管手
段と； ｄ 前記ポンプ手段に動力を供給するための動力
手段と； ｅ 前記動力手段から前記ポンプ手段に駆動力を
伝達するための前記導管内の駆動手段； とを具えることを特徴とする脈管内血液ポンプ。
２ 前記駆動手段が前記導管手段を経て延在する
可撓性のケーブルを含むようにしたことを特徴と
する請求の範囲第１項に記載のポンプ。
３ 前記回転ポンプ手段が、固定子および回転子
手段と、これらの固定子および回転子手段を相対
的に回転させるように取付ける軸受手段とを具
え；前記軸受手段をパージシールし；かつパージ
流体を前記導管手段を経て前記軸受手段に十分な
速度で放出させて、血液要素が前記パージシール
に入らないようにしたことを特徴とする請求の範
囲第１項に記載のポンプ。
４ 前記回転ポンプ手段をほぼ10000〜20000rpm
の回転速度で作動する軸流ポンプとしたことを特
徴とする請求の範囲第１項に記載のポンプ。
５ 前記回転ポンプ手段の血流速度を毎分当たり
ほぼ４リツトルとしたことを特徴とする請求の範
囲第１項に記載のポンプ。
技術分野 本発明は血液ポンプ、特に大手術をすることな
く脈管系内に経皮挿入して右または左心室の血液
流動を十分にすることにより一時的に心臓機能を
助けることのできる小形血液ポンプに関するもの
である。
背景技術 医者は心臓性シヨツクの症例（すなわち、心臓
はまだ機能しているも、患者を生存させるのには
十分な血液を送り出していない状態）に頻繁に直
面する。このような状態の緊急処置には、患者を
生存させるのに十分な程度に血流を維持する何等
かの形態の心臓機能救援手段がしばしば必要とさ
れるも、他の手段を着手して心臓そのものを一層
正常に機能すべく回復させる必要がある。
現在斯種の心臓機能救援手段に対する有効な方
法は、大手術をして脈管系に接続するポンプ装置
によるものか、または適当な動脈内に挿入するバ
ルーンカテーテルによるものだけである。遺憾な
がら、大手術は心臓性シヨツクの患者には時間が
かかり過ぎ、また危険を伴ない、しかもバルーン
カテーテルは心臓からの血液の送り出しを十分に
向上させることができない。
非開胸脈管接近法を用いて血液の左側循環を支
えることが提案されている。斯種の方式では２つ
の動脈部位を同時に用いて血液を心臓から動脈系
へと送り出すようにしている。しかし、この技法
には長くて孔の小さいカニユーレを使用する必要
があり、斯様なカニユーレでは圧力降下が大きく
なる。カニユーレの導管が負圧を受けると、空気
塞栓症および重い合併症をまねくことになる。さ
らに、ポンプを心臓に接近させるためには鎖骨下
動脈を用いてポンプを挿入する必要がある。斯か
る動脈への外科的接近法は大腿部動脈への場合よ
りもずつと困難である。
右心機能を支えるため外部ポンプを用いるに
は、２つの静脈部位にて同時に接近させる必要が
ある。この場合にはポンプ出力を長くて孔の小さ
いカニユーレによつて肺動脈に戻す必要がある。
この場合にも負圧による圧力降下が大きくて同様
な合併症や、場合によつては空気塞栓症が生じた
りする。従つて従来技術では心臓の血流を迅速に
十分なものして、重症患者を助けることのできる
簡単な構成で、危険度の低い血液循環救援装置を
提供することはできなかつた。
発明の開示 本発明は、末梢静脈または動脈系のいずれかを
介して右または左心室に直接接近させて、血液循
環を助けるのに十分な程度に小さい軸方向タイプ
を可とする高速小形血液ポンプを提供することに
より従来の諸問題を解決することにある。斯かる
装置は末梢経皮挿入するものであり、しかもその
装置の流量は毎分当り３〜４程度とすることが
できる。
右心室の機能を支えるにはポンプを三尖弁およ
び肺動脈弁を経て肺動脈内へと前向きに挿入す
る。斯様な処置は末梢血管から大腿部静脈，外頚
静脈または頭部付近の静脈を経て行うことができ
る。
左心室の機能を支えるにはポンプを大動脈弁を
経て左心室へと逆向きに挿入して行う。これは鎖
骨下動脈または大腿部静脈のいずれかから行うこ
とができる。
ポンプを周囲から接近させるのが困難な場合に
は、少し胸壁切開して脈管接近させることにより
ポンプを心室先端部へと導入させることができ
る。
本発明によるポンプは全身の循環通路の部位に
小直径のカニユーレを経て延在させる可撓性ケー
ブルまたは水圧管路を介して人体の外側における
小形動力ユニツトによつて駆動させる。
必要な血液を放出させるためには、本発明のポ
ンプを10000〜20000rpmの軸速度で作動させる必
要がある。このような高速回転ポンプは以前は血
液ポンプの用途には適さないと考えられていた。
その理由は、羽根車チヤンバの固定壁部付近を通
る羽根車の羽根の先端部がゼブリ溶血を生ぜしめ
る程に大きい剪断力を生ずるであろうと一般に考
えられていたからである。本発明は、羽根の先端
部の線速度がポンプの直径に依存し、このために
本発明によるような小形ポンプでは斯かる線速度
が十分に小さくなり、ポンプ動作に必要な速度で
もさほど溶血を生じないと云う認識に基づいて成
したものである。
本発明によるポンプでは、その回転部と固定部
との間にパージシールを用いることとによつて血
栓形成を回避させる。さらに、軸受潤滑剤として
作用し得るエタノールまたは同様な静菌剤をパー
ジ液体として用いることによつて静菌効果を達成
することもできる。
従つて、本発明の目的は心臓の機能を助ける目
的のために大手術をすることなく脈管系を経て心
臓に迅速に接近させることができ、しかも患者へ
の危険度が低い高容量小形血液ポンプを提供する
ことにある。
本発明の他の目的は血液凝固を阻止する上述し
たタイプのポンプを提供することにある。
【図面の簡単な説明】
第１ａ図は心臓機能を助ける目的のための本発
明ポンプの好適な位置付けの様子を示しているほ
ぼ大動脈平面での人間の心臓の切開図； 第１ｂ図は大腿部動脈を経て本発明ポンプの挿
入の様子を示している人間の概略図； 第２図は本発明ポンプの一部を概略的に示す軸
方向断面図； 第３ａ図および第３ｂ図は第２図のポンプの３
ａ−３ａおよび３ｂ，３ｂ線に沿う断片的横断面
図； 第４図は第２図のポンプの４−４線に沿う断片
的断面図である。
発明を実施するための最良の形態 本発明の脈管内血液ポンプ１０は、適当に短く
て、可撓性の送り込みカニユーレ１４を逆向きに
挿入することによつて大動脈弁１５を経て心臓１
１の左心室１２（第１ａ図）に接近させることが
できる。カニユーレ１４は、それを有利に挿入さ
せることのできる大腿部１８における大腿部動脈
１７（第１ｂ図）から大動脈１６を経て案内させ
る。ポンプ１０の作動時には血液が左心室１２か
らカニユーレ１４の入口素子１９およびカニユー
レ１４の内部を経てポンプ１０内に矢印（第１ａ
図）の方向に送り出される。ポンプ１０の出口に
は送り出された血液が出口素子２０を経て大動脈
１６へと放出される。
本発明ポンプを、ここでは大腿部動脈を経て逆
向きに挿入して左心室の機能を助けることについ
て述べたが、本発明ポンプはさほど変更しなくて
も所要に応じ他の挿入技法により上述したように
して左心室または右心室の機能を助けるように使
用することもできることは明らかである。
ポンプ１０は大腿部動脈１７および大動脈１６
内に入れたカテーテル２６を経て延在させる可撓
性の軸２４によつて駆動させるのが好適である。
カテーテル２６は下記に述べるような目的および
機能をするパージ流体用の導管としても作用す
る。ポンプ１０に動力を与えるのには軸２４代り
にカテーテル２６を用いる水圧系を同等に用いる
ことができる。
第１ａ図および第１ｂ図の配置では、患者の身
体の外側に置いた適当な支持ユニツト２８によつ
て軸２４に対する駆動力を与えると共に、カテー
テル２６を経てポンプ１０にパージ流体も与え
る。カテーテル２６の直径は十分小さくして、そ
れを動脈に挿入する際に血液がそのまわりを比較
的支障なく流れるようにする。
次に第２図に転ずるに、ポンプ１０はそのポン
プ本体に沿つてほぼ円筒形をしているハウジング
３０を有している。入口素子１９および出口素子
２０にはテーパーを付けて、患者の脈管系を経て
のポンプ１０の挿入および引出しをし易くする。
支持支柱３８（これは固定子羽根としても作用す
る）はハウジング３０を固定子支持軸受４０およ
びチユーブ取付け円錘部４２に接続する。
円筒状固定子ハブ４０はケーブル２４によつて
駆動されるような回転運動に対して回転子４４を
支持する。回転子４４の軸方向運動は軸受フラン
ジ４６によつて防止される。回転子４４は一連の
回転子羽根を支承し、これらの羽根の湾曲断面
（第４図に明示してある）は固定子羽根３６のそ
れに似ている。かし、各羽根リングにおける回転
子羽根の数は、第３図に明示したように、各リン
グにおける固定子羽根の数とは相違させる（例え
ば、回転子羽根はリング当り７個とし、固定子羽
根はリング当り11個とすることができる）。
ジヤーナル軸受４１はカテーテル２６を経てポ
ンプ１０内に圧力下で導入させるパージ流体を絶
えず流すことによつて滑らかにする。パージ流体
５０はフエースシール５２を経て流れ、最終的に
は界面５６の個所にて血流５４に放出される。
1983年９月28日出願の凝血抑制血液ポンプなる名
称の同時係属米国特許出願第537243号に記載した
ように、ポンプ１０内での血栓形成は、環状界面
５６に沿つてパージ流体を十分に流出し続けて界
面５６の個所にて血液要素が回転子および固定子
表面に接触しないようにすることによつて防止さ
れる。
本発明のポンプは極めて小さくする必要があ
る。その外径は理想的には７〜９mm以下とすべき
である。ほぼ４／分の流量で必要な血液を流す
ためには、本発明のポンプをほぼ10000〜
20000rpmの速度で作動させる必要がある。ポン
プの作動時には、羽根３６および４８の先端部が
絶えず回転子４４およびハウジング３０にそれぞ
れ接近して動く第２図の５８および６０の個所に
おける羽根先の環状領域にて剪断作用が生ずる。
しかし、ポンプの寸法が極めて小さいため、領域
５８にて生ずる最悪のケースでのハウジング３０
に対する羽根４８の先端部の相対運動は５ｍ／秒
以下に留まる。この相対速度は、羽根先端部の適
当な隙間（ほぼ0.1mm）と相俟つてスペース５８
内の剪断力を十分低いレベルに維持して、不当な
溶血を生ぜしめなくするに十分な低い値である。
スペース６０の方がスペース５８よりもポンプ１
０の軸線に近いために、固定子羽根３６と回転子
４４との間の相対速度が小さくなるので、スペー
ス６０内での赤血球細胞膜の破壊は一層少なくな
る。
本発明は手術することなく、しかも患者への危
険も最小にして迅速にあてがうことができ、かつ
取外すことのできる有効な脈管心臓機能救援方法
および装置を提供すること明らかである。
JP59503865A 1983-09-28 1984-09-28 経皮接近を利用する高容量の脈管内血液ポンプ Granted JPS61500059A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/537,244 US4625712A (en) 1983-09-28 1983-09-28 High-capacity intravascular blood pump utilizing percutaneous access
US537244 1995-09-29

Publications (2)

Publication Number Publication Date
JPS61500059A JPS61500059A (ja) 1986-01-16
JPH0531423B2 true JPH0531423B2 (ja) 1993-05-12

Family

ID=24141837

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59503865A Granted JPS61500059A (ja) 1983-09-28 1984-09-28 経皮接近を利用する高容量の脈管内血液ポンプ

Country Status (7)

Country Link
US (1) US4625712A (ja)
EP (1) EP0157871B1 (ja)
JP (1) JPS61500059A (ja)
BR (1) BR8407086A (ja)
CA (1) CA1240802A (ja)
DE (1) DE3482656D1 (ja)
WO (1) WO1985001432A1 (ja)

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EP0157871B1 (en) 1990-07-04
US4625712A (en) 1986-12-02
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BR8407086A (pt) 1985-08-13
CA1240802A (en) 1988-08-23

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