JPH05502603A - 骨インプラント用生物活性ガラス状組成物、それから造られたフィラメント及び方法 - Google Patents

骨インプラント用生物活性ガラス状組成物、それから造られたフィラメント及び方法

Info

Publication number: JPH05502603A
Authority: JP; Japan
Prior art keywords: bone; composition; filament; glassy; produced
Prior art date: 1990-02-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP3503103A

Other languages

English (en)

Japanese (ja)

Inventor

ビタ・フィンツィ・ザルマン、エミリオ

ロカルディ、ブルノ

ガッビー、カルロ

トランクィリ・レアリ、パオロ

Original Assignee

エッセ・エ・イ・ピ・イ・ソシエタ・エスポルタツィオーネ・インポルタツィオーネ・プロドッチ・インデュストリアリ・ソシエタ・ペル・アチオニ

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-08

Filing date

1991-02-04

Publication date

1993-05-13

1991-02-04 Application filed by エッセ・エ・イ・ピ・イ・ソシエタ・エスポルタツィオーネ・インポルタツィオーネ・プロドッチ・インデュストリアリ・ソシエタ・ペル・アチオニ filed Critical エッセ・エ・イ・ピ・イ・ソシエタ・エスポルタツィオーネ・インポルタツィオーネ・プロドッチ・インデュストリアリ・ソシエタ・ペル・アチオニ

1993-05-13 Publication of JPH05502603A publication Critical patent/JPH05502603A/ja

Status Pending legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title claims description 67
210000000988 bone and bone Anatomy 0.000 title claims description 44
239000007943 implant Substances 0.000 title claims description 13
230000000975 bioactive effect Effects 0.000 title claims description 10
238000000034 method Methods 0.000 title claims description 9
239000000835 fiber Substances 0.000 claims description 32
239000002245 particle Substances 0.000 claims description 24
239000000843 powder Substances 0.000 claims description 14
239000000463 material Substances 0.000 claims description 13
230000007547 defect Effects 0.000 claims description 10
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 6
229910052593 corundum Inorganic materials 0.000 claims description 5
229910001845 yogo sapphire Inorganic materials 0.000 claims description 5
KKCBUQHMOMHUOY-UHFFFAOYSA-N Na2O Inorganic materials [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 claims description 3
238000005516 engineering process Methods 0.000 claims description 3
239000007921 spray Substances 0.000 claims description 3
229920000742 Cotton Polymers 0.000 claims description 2
WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 claims description 2
229910001634 calcium fluoride Inorganic materials 0.000 claims description 2
239000011247 coating layer Substances 0.000 claims description 2
GUYBGCBOZOALMT-UHFFFAOYSA-J dicalcium;fluoride;phosphate Chemical compound [F-].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O GUYBGCBOZOALMT-UHFFFAOYSA-J 0.000 claims description 2
239000012634 fragment Substances 0.000 claims description 2
239000004753 textile Substances 0.000 claims description 2
238000004519 manufacturing process Methods 0.000 claims 2
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
150000001875 compounds Chemical class 0.000 claims 1
238000005520 cutting process Methods 0.000 claims 1
238000002513 implantation Methods 0.000 claims 1
239000004615 ingredient Substances 0.000 claims 1
239000010410 layer Substances 0.000 claims 1
229910052697 platinum Inorganic materials 0.000 claims 1
238000002360 preparation method Methods 0.000 claims 1
239000007787 solid Substances 0.000 claims 1
230000000087 stabilizing effect Effects 0.000 claims 1
239000011521 glass Substances 0.000 description 19
210000002805 bone matrix Anatomy 0.000 description 9
239000011159 matrix material Substances 0.000 description 9
239000008280 blood Substances 0.000 description 6
210000004369 blood Anatomy 0.000 description 6
210000004027 cell Anatomy 0.000 description 6
238000002474 experimental method Methods 0.000 description 5
230000008569 process Effects 0.000 description 5
MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 4
239000000919 ceramic Substances 0.000 description 4
239000004744 fabric Substances 0.000 description 4
239000000499 gel Substances 0.000 description 4
241001465754 Metazoa Species 0.000 description 3
230000002776 aggregation Effects 0.000 description 3
230000008468 bone growth Effects 0.000 description 3
230000001054 cortical effect Effects 0.000 description 3
238000004090 dissolution Methods 0.000 description 3
238000011835 investigation Methods 0.000 description 3
230000002188 osteogenic effect Effects 0.000 description 3
-1 For example Substances 0.000 description 2
UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
238000005054 agglomeration Methods 0.000 description 2
230000009286 beneficial effect Effects 0.000 description 2
239000011230 binding agent Substances 0.000 description 2
230000004071 biological effect Effects 0.000 description 2
230000008512 biological response Effects 0.000 description 2
210000002449 bone cell Anatomy 0.000 description 2
230000010072 bone remodeling Effects 0.000 description 2
230000001413 cellular effect Effects 0.000 description 2
230000008859 change Effects 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
229910052588 hydroxylapatite Inorganic materials 0.000 description 2
230000002757 inflammatory effect Effects 0.000 description 2
230000003993 interaction Effects 0.000 description 2
239000000395 magnesium oxide Substances 0.000 description 2
CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 2
239000012528 membrane Substances 0.000 description 2
210000000963 osteoblast Anatomy 0.000 description 2
210000005009 osteogenic cell Anatomy 0.000 description 2
239000011236 particulate material Substances 0.000 description 2
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 2
238000001556 precipitation Methods 0.000 description 2
239000000126 substance Substances 0.000 description 2
238000012360 testing method Methods 0.000 description 2
239000010936 titanium Substances 0.000 description 2
229910052719 titanium Inorganic materials 0.000 description 2
210000002268 wool Anatomy 0.000 description 2
239000005995 Aluminium silicate Substances 0.000 description 1
102000008186 Collagen Human genes 0.000 description 1
108010035532 Collagen Proteins 0.000 description 1
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
229920002683 Glycosaminoglycan Polymers 0.000 description 1
206010020772 Hypertension Diseases 0.000 description 1
229910019714 Nb2O3 Inorganic materials 0.000 description 1
241000283973 Oryctolagus cuniculus Species 0.000 description 1
208000006735 Periostitis Diseases 0.000 description 1
241000700159 Rattus Species 0.000 description 1
208000007536 Thrombosis Diseases 0.000 description 1
238000004125 X-ray microanalysis Methods 0.000 description 1
230000009471 action Effects 0.000 description 1
238000004220 aggregation Methods 0.000 description 1
235000012211 aluminium silicate Nutrition 0.000 description 1
230000004888 barrier function Effects 0.000 description 1
239000005313 bioactive glass Substances 0.000 description 1
230000031018 biological processes and functions Effects 0.000 description 1
230000017531 blood circulation Effects 0.000 description 1
210000001185 bone marrow Anatomy 0.000 description 1
239000001506 calcium phosphate Substances 0.000 description 1
229910000389 calcium phosphate Inorganic materials 0.000 description 1
235000011010 calcium phosphates Nutrition 0.000 description 1
239000002775 capsule Substances 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
HPNSNYBUADCFDR-UHFFFAOYSA-N chromafenozide Chemical compound CC1=CC(C)=CC(C(=O)N(NC(=O)C=2C(=C3CCCOC3=CC=2)C)C(C)(C)C)=C1 HPNSNYBUADCFDR-UHFFFAOYSA-N 0.000 description 1
230000004087 circulation Effects 0.000 description 1
230000035602 clotting Effects 0.000 description 1
239000011248 coating agent Substances 0.000 description 1
238000000576 coating method Methods 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
210000002808 connective tissue Anatomy 0.000 description 1
238000010276 construction Methods 0.000 description 1
239000013078 crystal Substances 0.000 description 1
210000000805 cytoplasm Anatomy 0.000 description 1
230000007423 decrease Effects 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
230000006866 deterioration Effects 0.000 description 1
238000011161 development Methods 0.000 description 1
239000000428 dust Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
210000003722 extracellular fluid Anatomy 0.000 description 1
239000002657 fibrous material Substances 0.000 description 1
239000012530 fluid Substances 0.000 description 1
239000003365 glass fiber Substances 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
238000007373 indentation Methods 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 1
239000000155 melt Substances 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
239000003607 modifier Substances 0.000 description 1
239000006060 molten glass Substances 0.000 description 1
230000003448 neutrophilic effect Effects 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
210000002997 osteoclast Anatomy 0.000 description 1
210000003460 periosteum Anatomy 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
230000000750 progressive effect Effects 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
239000011044 quartzite Substances 0.000 description 1
230000009257 reactivity Effects 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
238000004626 scanning electron microscopy Methods 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
229910001948 sodium oxide Inorganic materials 0.000 description 1
238000005507 spraying Methods 0.000 description 1
238000005728 strengthening Methods 0.000 description 1
239000000758 substrate Substances 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1
230000008961 swelling Effects 0.000 description 1
ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 description 1
210000002303 tibia Anatomy 0.000 description 1
238000013519 translation Methods 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C3/00—Glass compositions
- C03C3/04—Glass compositions containing silica
- C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
- C03C3/097—Glass compositions containing silica with 40% to 90% silica, by weight containing phosphorus, niobium or tantalum
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Inorganic Chemistry (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Geochemistry & Mineralogy (AREA)
Materials Engineering (AREA)
Ceramic Engineering (AREA)
Molecular Biology (AREA)
Materials For Medical Uses (AREA)
Secondary Cells (AREA)
Electric Propulsion And Braking For Vehicles (AREA)

JP3503103A 1990-02-08 1991-02-04 骨インプラント用生物活性ガラス状組成物、それから造られたフィラメント及び方法 Pending JPH05502603A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT67096A IT1240938B (it)	1990-02-08	1990-02-08	Composizione vetrosa bioattiva per impianti ossei e prodotti ottenuti con tale composizione o che la comprendono
IT67096A/90		1990-02-08

Publications (1)

Publication Number	Publication Date
JPH05502603A true JPH05502603A (ja)	1993-05-13

Family

ID=11299541

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP3503103A Pending JPH05502603A (ja)	1990-02-08	1991-02-04	骨インプラント用生物活性ガラス状組成物、それから造られたフィラメント及び方法

Country Status (10)

Country	Link
EP (1)	EP0514401A1 (fr)
JP (1)	JPH05502603A (fr)
KR (1)	KR950008173B1 (fr)
AU (1)	AU639981B2 (fr)
BR (1)	BR9106030A (fr)
CA (1)	CA2075281A1 (fr)
FI (1)	FI923561A7 (fr)
HU (1)	HUT61899A (fr)
IT (1)	IT1240938B (fr)
WO (1)	WO1991012032A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2682968B1 (fr) *	1991-10-28	1994-08-26	Icmc	Procede de realisation d'un implant osseux, dispositif permettant de mettre en óoeuvre le procede et implant ainsi realise.
WO1993017976A1 (fr) *	1992-03-09	1993-09-16	Turku Implant Team Oy	Verre bioactif utilise comme substitut osseux
US6121172A (en) *	1993-11-15	2000-09-19	The Trustees Of The University Of Pennsylvania	Composite materials using bone bioactive glass and ceramic fibers
US5468544A (en) *	1993-11-15	1995-11-21	The Trustees Of The University Of Pennsylvania	Composite materials using bone bioactive glass and ceramic fibers
FI101129B (sv) *	1995-01-13	1998-04-30	Vivoxid Oy	Nya bioaktiva glas och deras användning
FI110063B (fi) *	1998-12-11	2002-11-29	Antti Yli-Urpo	Uusi bioaktiivinen tuote ja sen käyttö
FI117963B (fi)	2001-04-26	2007-05-15	Eija Marjut Pirhonen	Luuta korvaavat materiaalit
AU2007268175B2 (en)	2006-05-26	2013-05-23	Baxter Healthcare S.A.	Injectable fibrin composition for bone augmentation
ATE452863T1 (de)	2006-09-20	2010-01-15	Inion Oy	Bioaktive glaszusammensetzungen
EP2142224B1 (fr)	2007-04-23	2016-03-23	Baxter International Inc.	Compositions de fibrine contenant des composés de strontium
US10751367B2 (en)	2016-05-27	2020-08-25	Corning Incorporated	Bioactive glass microspheres
US20170342383A1 (en)	2016-05-27	2017-11-30	Corning Incorporated	Lithium disilicate glass-ceramic compositions and methods thereof
CN111417603B (zh)	2017-11-28	2023-10-31	康宁股份有限公司	生物活性硼酸盐玻璃及其方法
CN111433165A (zh) *	2017-11-28	2020-07-17	康宁股份有限公司	高液相线粘度生物活性玻璃
WO2019108556A1 (fr)	2017-11-28	2019-06-06	Corning Incorporated	Compositions de verre bioactif et restauration de l'hypersensibilité de la dentine
TWI794344B (zh)	2017-11-28	2023-03-01	美商康寧公司	經化學強化之生物活性玻璃陶瓷
WO2020236501A1 (fr) *	2019-05-22	2020-11-26	Corning Incorporated	Compositions de verre bioactives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1477899A (en) *	1973-09-17	1977-06-29	Leitz Ernst Gmbh	Manufacture of therapeutically useful composite materials
JPS573739A (en) *	1980-06-11	1982-01-09	Nippon Kogaku Kk <Nikon>	Bioactive glass and glass ceramic
JPS58118746A (ja) *	1982-01-07	1983-07-14	株式会社ニコン	歯科用インプラント及びその製造方法
CA1250494A (fr) *	1984-03-01	1989-02-28	Chhattar S. Kucheria	Liaisonnement d'enduits de verre bio-actifs
JPS60186455A (ja) *	1984-03-06	1985-09-21	株式会社ニコン	アパタイトコンポジツトセラミクス
US4960733A (en) *	1987-02-28	1990-10-02	Hoya Corporation	Inorganic biomaterial and process for producing the same
JPH02149447A (ja) *	1988-12-01	1990-06-08	Nippon Electric Glass Co Ltd	歯科用結晶化ガラス

1990
- 1990-02-08 IT IT67096A patent/IT1240938B/it active IP Right Grant
1991
- 1991-02-04 FI FI923561A patent/FI923561A7/fi not_active Application Discontinuation
- 1991-02-04 CA CA002075281A patent/CA2075281A1/fr not_active Abandoned
- 1991-02-04 BR BR919106030A patent/BR9106030A/pt not_active Application Discontinuation
- 1991-02-04 WO PCT/EP1991/000201 patent/WO1991012032A1/fr not_active Ceased
- 1991-02-04 KR KR1019920701897A patent/KR950008173B1/ko not_active Expired - Lifetime
- 1991-02-04 HU HU9202578A patent/HUT61899A/hu unknown
- 1991-02-04 EP EP91902954A patent/EP0514401A1/fr not_active Withdrawn
- 1991-02-04 JP JP3503103A patent/JPH05502603A/ja active Pending
- 1991-02-04 AU AU71491/91A patent/AU639981B2/en not_active Ceased

Also Published As

Publication number	Publication date
CA2075281A1 (fr)	1991-08-09
EP0514401A1 (fr)	1992-11-25
FI923561A0 (fi)	1992-08-07
IT1240938B (it)	1993-12-27
AU7149191A (en)	1991-09-03
FI923561L (fi)	1992-08-07
IT9067096A1 (it)	1991-08-08
BR9106030A (pt)	1993-03-02
KR950008173B1 (ko)	1995-07-26
FI923561A7 (fi)	1992-08-07
IT9067096A0 (it)	1990-02-08
HUT61899A (en)	1993-03-29
WO1991012032A1 (fr)	1991-08-22
AU639981B2 (en)	1993-08-12

Publication	Publication Date	Title
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