JPH05504774A - エイズ治療を増進するためのメタロポルフィリン類の使用 - Google Patents

エイズ治療を増進するためのメタロポルフィリン類の使用

Info

Publication number
JPH05504774A
JPH05504774A JP3514118A JP51411891A JPH05504774A JP H05504774 A JPH05504774 A JP H05504774A JP 3514118 A JP3514118 A JP 3514118A JP 51411891 A JP51411891 A JP 51411891A JP H05504774 A JPH05504774 A JP H05504774A
Authority
JP
Japan
Prior art keywords
heme
azt
acid addition
treatment
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3514118A
Other languages
English (en)
Japanese (ja)
Inventor
カパス,アタラー
レヴェレ,リチャード ディ.
アブラハム,ネイダー ジイ.
ブチャー,ドリス ジェイ.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Original Assignee
Rockefeller University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rockefeller University filed Critical Rockefeller University
Publication of JPH05504774A publication Critical patent/JPH05504774A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP3514118A 1990-07-31 1991-07-25 エイズ治療を増進するためのメタロポルフィリン類の使用 Pending JPH05504774A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56019190A 1990-07-31 1990-07-31
US560,191 1990-07-31
US73509091A 1991-07-24 1991-07-24
US735,090 1991-07-24

Publications (1)

Publication Number Publication Date
JPH05504774A true JPH05504774A (ja) 1993-07-22

Family

ID=27072276

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3514118A Pending JPH05504774A (ja) 1990-07-31 1991-07-25 エイズ治療を増進するためのメタロポルフィリン類の使用

Country Status (5)

Country Link
EP (1) EP0543902A4 (de)
JP (1) JPH05504774A (de)
AU (1) AU645131B2 (de)
CA (1) CA2088593A1 (de)
WO (1) WO1992002242A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005285A1 (en) * 1992-09-03 1994-03-17 The Regents Of The University Of California Metallo porphyrin compositions
AU1296795A (en) * 1993-12-28 1995-07-17 New York Blood Center, Inc., The Methods for preventing or treating hiv-1 or hiv-2 infection
TW247876B (en) 1993-12-28 1995-05-21 New York Blood Ct Inc Pharmaceutical compositions for prevention or treating HIV-1 or HIV-2 infection
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
EP0939644B1 (de) * 1996-08-27 2004-01-14 Hemosol Inc. Gesteigerte stimulation der erythropoesis
AU765856B2 (en) * 1996-08-27 2003-10-02 Hemosol Inc. Enhanced stimulation of erythropoiesis
US20020072512A1 (en) * 2000-12-08 2002-06-13 Metaphore Pharmaceuticals, Inc Method of preventing and treating HIV-mediated central nervous system damage
AU2003258604A1 (en) * 2002-03-28 2003-10-13 Exponential Biotherapies, Inc. Oxygenating agents for enhancing host responses to microbial infections
GB0519169D0 (en) 2005-09-21 2005-10-26 Leuven K U Res & Dev Novel anti-viral strategy
RU2475498C1 (ru) * 2011-11-17 2013-02-20 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Новые производные гемина с антибактериальной и противовирусной активностью

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049493A (en) * 1987-10-23 1991-09-17 California Institute Of Technology Enhancement of cell growth by expression of a cloned hemoglobin gene
EP0337598A3 (de) * 1988-02-26 1991-07-03 Georgia State University Foundation, Inc. Verwendung von Porphyrinen und Metalloporphyrinen zur Behandlung von durch HIV verursachten Krankheiten
US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions

Also Published As

Publication number Publication date
WO1992002242A1 (en) 1992-02-20
EP0543902A1 (de) 1993-06-02
CA2088593A1 (en) 1992-02-01
EP0543902A4 (en) 1993-10-27
AU645131B2 (en) 1994-01-06
AU8410491A (en) 1992-03-02

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