JPH05504774A - エイズ治療を増進するためのメタロポルフィリン類の使用 - Google Patents

エイズ治療を増進するためのメタロポルフィリン類の使用

Info

Publication number
JPH05504774A
JPH05504774A JP3514118A JP51411891A JPH05504774A JP H05504774 A JPH05504774 A JP H05504774A JP 3514118 A JP3514118 A JP 3514118A JP 51411891 A JP51411891 A JP 51411891A JP H05504774 A JPH05504774 A JP H05504774A
Authority
JP
Japan
Prior art keywords
heme
azt
acid addition
treatment
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3514118A
Other languages
English (en)
Japanese (ja)
Inventor
カパス，アタラー
レヴェレ，リチャード　ディ．
アブラハム，ネイダー　ジイ．
ブチャー，ドリス　ジェイ．
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Original Assignee
Rockefeller University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rockefeller University filed Critical Rockefeller University
Publication of JPH05504774A publication Critical patent/JPH05504774A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP3514118A 1990-07-31 1991-07-25 エイズ治療を増進するためのメタロポルフィリン類の使用 Pending JPH05504774A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56019190A 1990-07-31 1990-07-31
US560,191 1990-07-31
US73509091A 1991-07-24 1991-07-24
US735,090 1991-07-24

Publications (1)

Publication Number Publication Date
JPH05504774A true JPH05504774A (ja) 1993-07-22

Family

ID=27072276

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3514118A Pending JPH05504774A (ja) 1990-07-31 1991-07-25 エイズ治療を増進するためのメタロポルフィリン類の使用

Country Status (5)

Country Link
EP (1) EP0543902A4 (fr)
JP (1) JPH05504774A (fr)
AU (1) AU645131B2 (fr)
CA (1) CA2088593A1 (fr)
WO (1) WO1992002242A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE201595T1 (de) * 1992-09-03 2001-06-15 Univ California Metallporphyrinzusammensetzungen
TW247876B (en) 1993-12-28 1995-05-21 New York Blood Ct Inc Pharmaceutical compositions for prevention or treating HIV-1 or HIV-2 infection
WO1995017893A1 (fr) * 1993-12-28 1995-07-06 New York Blood Center Methodes destinees a prevenir ou a traiter l'infection a vih-1 ou vih-2
US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
AU765856B2 (en) * 1996-08-27 2003-10-02 Hemosol Inc. Enhanced stimulation of erythropoiesis
WO1998008537A1 (fr) * 1996-08-27 1998-03-05 Hemosol Inc. Stimulation amelioree de l'erythropoiese
US20020072512A1 (en) * 2000-12-08 2002-06-13 Metaphore Pharmaceuticals, Inc Method of preventing and treating HIV-mediated central nervous system damage
EP1519750A2 (fr) * 2002-03-28 2005-04-06 Exponential Biotherapies, Inc. Utilisation d'agents oxygenants pour accroitre la reponse d'un hote aux infections
GB0519169D0 (en) 2005-09-21 2005-10-26 Leuven K U Res & Dev Novel anti-viral strategy
RU2475498C1 (ru) 2011-11-17 2013-02-20 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Новые производные гемина с антибактериальной и противовирусной активностью

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049493A (en) * 1987-10-23 1991-09-17 California Institute Of Technology Enhancement of cell growth by expression of a cloned hemoglobin gene
EP0337598A3 (fr) * 1988-02-26 1991-07-03 Georgia State University Foundation, Inc. Utilisation de porphyrines et de métalloporphyrines dans le traitement de maladies causées par HIV
US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions

Also Published As

Publication number Publication date
AU645131B2 (en) 1994-01-06
EP0543902A4 (en) 1993-10-27
CA2088593A1 (fr) 1992-02-01
AU8410491A (en) 1992-03-02
EP0543902A1 (fr) 1993-06-02
WO1992002242A1 (fr) 1992-02-20

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JPH02145527A (ja) エイズ治療および阻害剤