JPH0597645A - Cosmetic - Google Patents

Abstract

PURPOSE:To obtain a cosmetic, not only having excellent ultraviolet ray screening effects but also providing natural finish with high transparency without whiteness and good in feeling of use. CONSTITUTION:A cosmetic is obtained by blending one or more of a metallic salt of an amino acid, preferably zinc glycinate, zinc glutamate, zinc salt of alanine, zinc salt of valine, zinc salt of methionine or zinc salt of lysine having 0.01-50mum, preferably 0.1-20mum particle diameter, especially the zinc glycinate or zinc glutamate in an amount of 0.01-95wt.%, preferably 0.1-50wt.% based on the total amount of the cosmetic as an active ingredient with other ingredients. This cosmetic has the above-mentioned effects. Furthermore, when the metallic salt of the amino acid is blended in the cosmetic, surface treatment such as surface coating treatment with usually well-known raw materials of fats and oils, etc., treatment with an activator or a metallic soap, etc., are carried out for the purpose of utilizing characteristics of the metallic salt and improving dispersibility and usability. The resultant metallic salt of the amino acid can further be blended.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to cosmetics. More specifically, it is a cosmetic product characterized by containing an amino acid metal salt as an active ingredient, which not only protects the skin from harmful ultraviolet rays, but also has a natural finish with high transparency without whiteness and a good usability. Regarding

[0002]

2. Description of the Related Art Conventionally, various cosmetics containing metal oxides such as titanium oxide and zinc oxide as active ingredients are known to have an excellent protective action against ultraviolet rays. .. However,
Since these cosmetics have too large a covering power, when they are applied to the skin, the cosmetic film becomes white, resulting in an unnatural finish such as a thick makeup. Further, in order to eliminate the defects of these powders or to further enhance the protective action against ultraviolet rays, particles of fine particle powder such as titanium oxide to be incorporated into cosmetics are streaked when applied to the skin because the particles are too fine. There was a problem such as the cause of the above and powder entering the skin groove and pores, resulting in an unnatural finish.

[0003]

In view of the above points, the inventors of the present invention have conducted extensive studies to solve the above problems, and as a result, by adding an amino acid metal salt as an active ingredient, an excellent ultraviolet blocking effect was obtained. The present invention has been completed based on the finding that a cosmetic having not only whiteness but also a natural finish with high transparency and a good feeling of use can be obtained.

That is, the present invention relates to a cosmetic composition containing an amino acid metal salt as an active ingredient.
Furthermore, the present invention provides that the content of the amino acid metal salt is 0.01 to 95% by weight of the total amount of the cosmetic, the particle size of the amino acid metal salt is 0.01 to 50 μm, the amino acid metal salt is glycine zinc, and the amino acid The present invention relates to a cosmetic, wherein the metal salt is zinc glutamate.

[0005]

EXAMPLE The particle size of the amino acid metal salt used in the present invention is 0.01 to 50 μm, preferably 0.1 to 20 μm. If the particle size is 0.01 μm or less, powder will enter the skin grooves and pores, resulting in an unnatural finish. Further, if it is 50 μm or more, the skin has a feeling of strangeness.

The amino acid metal salt is 0.01% of the total amount of cosmetics.
~ 95% (wt%, the same applies below), preferably 0.1 to 50%. If the blending amount is 0.01% or less, the expected effects such as the above-mentioned ultraviolet ray blocking cannot be obtained, and if the blending amount is 95% or more, white makeup is not noticeable and a natural finish cosmetic film cannot be obtained.

The amino acid of the amino acid metal salt may be an aliphatic amino acid, an aromatic amino acid or a heterocyclic amino acid. For example, monoaminomonocarboxylic acids such as glycine, alanine, and valine; oxyamino acids such as serine and threonine; sulfur-containing amino acids such as cysteine and methionion; monoaminodicarboxylic acids such as aspartic acid and glutamic acid; diaminomonocarboxylic acids such as lysine. Aliphatic amino acids such as are preferred examples. Among these, glycine, alanine, and glutamic acid are particularly preferable in view of the appearance color of powder, stability, and feeling of use.

The metal of the amino acid metal salt is, for example,
Alkaline earth metals such as Mg, Ca, Ba, Zn, A
Among these, Zn is particularly preferable from the viewpoints of safety and stability when incorporated into cosmetics.

Taking zinc salts as examples of amino acid metal salts, zinc glycine, zinc glutamate, zinc alanine, zinc valine, zinc methionine, zinc lysine and the like are preferably used. The amino acid metal salt may be blended alone or in combination of two or more in the cosmetic of the present invention.

When an amino acid metal salt is blended in a cosmetic composition, in order to take advantage of its properties and improve the dispersibility and usability, a surface coating treatment with a generally known raw material of fats and oils, an activator treatment, a metal soap It is also possible to mix after performing surface treatment such as treatment.

In addition to the amino acid metal salt, the cosmetics of the present invention include, in addition to the amino acid metal salts, oily components (oils and fats) generally used in cosmetics, aqueous components (humectants, etc.), polymer compounds,
Surfactants, fragrances, preservatives / antioxidants, ultraviolet absorbers, pigments, and other various components are appropriately blended according to the application.

Examples of the oily components (oils and fats) include olive oil, castor oil, squalane, liquid paraffin, paraffin, cetyl alcohol, stearyl alcohol, stearic acid, oleic acid, isopropyl palmitate, isopropyl myristate, octyl myristate. Dodecyl, malic acid diisostearate, hydrogenated lecithin, beeswax, lanolin, methyl polysiloxane and the like can be mentioned.

Examples of the aqueous component (humectant, etc.) include glycerin, sorbit solution, propylene glycol, 1,3-butylene glycol, polyethylene glycol and the like.

Examples of the polymer compound include xanthan gum, gum arabic, carrageenan, tragacanth, carboxyvinyl polymer, polyvinyl alcohol, polyvinylpyrrolidone, sodium polyacrylate, methyl cellulose, ethyl cellulose and the like.

Examples of the surfactant include sorbitan monostearate, sorbitan monopalmitate, diglyceryl monostearate, diglyceryl monooleate, glyceryl monostearate, polyoxyethylene glycerin monostearate, polyoxyethylene sorbitan monosate. Examples include laurate and polyoxyethylene hydrogenated castor oil.

Examples of the antiseptic / antioxidant include paraoxybenzoic acid ester, dehydroacetic acid (and its salts), sorbic acid (and its salts), lysozyme chloride, butylhydroxytoluene, butylhydroxyanisole and the like.

Examples of the ultraviolet absorber include urocanic acid, ethyl urocanate, oxybenzone, octyl salicylate, dihydroxybenzophenone, paraaminobenzoic acid, octyl paradimethylaminobenzoate,
Examples include octyl methoxycinnamate.

Examples of the pigments include tar pigments, talc, kaolin, mica, sericite, titanium oxide, titanium mica, iron oxide yellow, red iron oxide, black iron oxide, bentonite, zinc oxide, magnesium oxide, silicic acid, nylon. Examples include powder.

Examples of the various other components include sodium hyaluronate, proteins, peptides, amino acids, vitamins, crude drug extracts and the like.

The blending amount of each of these cosmetic ingredients cannot be unconditionally determined because it varies depending on the intended use of the cosmetic and the like, and it is preferably blended appropriately according to the intended use.

The form of the cosmetic of the present invention is arbitrary and is not limited, but it has the property of preventing sunburn due to its excellent UV-blocking effect, so that it can be used as a basic cosmetic such as cream, emulsion, lotion, etc. Makeup cosmetics such as powder foundation and liquid foundation can be given.

Next, the present invention will be described in more detail with reference to examples, but the present invention is not limited thereto.

Formulation 1 (sunscreen cream) [A component] (%) Squalane 10.0 Isopropyl palmitate 5.0 Hydrogenated lecithin 3.0 Cetyl alcohol 2.0 Dibutylhydroxytoluene 0.04 Octyl methoxycinnamate 5.0 [B component] Purified water Remaining amount Propylene Glycol 8.0 Para-aminobenzoic acid ester 0.2 [Component C] Glycine zinc (average particle size 1.6 μm) 2.0 (Production method) Component B was heated to 80 ° C., component C was added, and the mixture was uniformly dispersed with a homomixer ( D component). A component is 80
The mixture was heated to ° C, the component D was added, and the mixture was uniformly dispersed and emulsified with a homomixer. Then, the mixture was stirred and cooled to 30 ° C. to obtain a cream.

Formulation Example 2 (Sunscreen milky lotion) [A component] (%) Liquid paraffin 5.0 Stearic acid 4.0 Cetyl alcohol 1.0 Sorbitan monostearate 1.0 Isopropyl myristate 1.0 Octyl methoxycinnamate 3.0 Dibutylhydroxytoluene 0.02 [B component] Purified water Residual amount 1,3-butylene glycol 4.0 Paraoxybenzoic acid ester 0.2 Potassium hydroxide 0.2 Sodium dehydroacetate 0.05 Xanthan gum 0.2 [C component] Glycine zinc (average particle size 1.6 μm) 1.0 (Manufacturing method) After heating, the C component was added and uniformly dispersed by a homomixer (D component). A component is 80
The mixture was heated to ° C, the component D was added, and the mixture was uniformly dispersed and emulsified with a homomixer. Then, the mixture was stirred and cooled to 30 ° C. to obtain an emulsion.

Formulation Example 3 (Sunscreen lotion) [A component] (%) Remaining amount of purified water Glycerin 5.0 Solbit solution 4.0 Propylene glycol 5.0 Paraoxybenzoic acid ester 0.2 Ethyl alcohol 5.0 Xanthan gum 0.01 Sodium hyaluronate 0.05 Crude drug extract 1.0 [B component ] Zinc glutamate (average particle size: 3.1 μm) 1.0 (Production method) After completely dissolving the component A with stirring, the component B was added and uniformly dispersed to obtain a lotion.

Formulation 4 (Sunscreen liquid foundation) [A component] (%) Liquid paraffin 4.0 Octyl dodecyl myristate 1.5 Octyl methoxycinnamate 3.0 Stearic acid 2.0 Cetyl alcohol 0.5 Dichryceryl monostearate 1.5 Vitamin E 0.2 [B Components] Purified water Remaining amount 1,3-butylene glycol 10.0 Paraoxybenzoic acid ester 0.2 Triethanolamine 0.4 Bentonite 2.0 Ethyl alcohol 5.0 [C component] Talc 0.9 Silicic acid 0.3 Titanium oxide 2.0 Glycine zinc (average particle size 3.7 μm) 5.0 Yellow iron oxide 0.9 Red iron oxide 0.2 Black iron oxide 0.1 (Production method) C component was uniformly dispersed by a pulverizer, then mixed with B component heated to 75 ° C. and sufficiently dispersed by a homomixer (D component). The component A was heated to 75 ° C., the component D was added, and the mixture was uniformly dispersed and emulsified with a homomixer. Then, the mixture was stirred and cooled to 30 ° C. to obtain a liquid foundation.

Formulation Example 5 (Sunscreen powder foundation) [A component] (%) Sericite remaining amount Talc 20.0 Kaolin 10.0 Nylon powder 8.0 Zinc glutamate (average particle size 3.1 μm) 10.0 Sodium dehydroacetate 0.1 Mica titanium 5.0 Iron oxide yellow 2.4 Bengal 1.0 Iron oxide black 0.1 [B component] Methyl polysiloxane 7.0 Liquid paraffin 2.0 Diisostearyl malate 3.0 Paraoxybenzoic acid ester 0.1 Octyl methoxysilicate 0.5 (Manufacturing method) A component is mixed with a grinder. And melted by heating B
The ingredients were added and further dispersed uniformly by a pulverizer. Then, it was filled in a predetermined container and molded to obtain a powder foundation.

Comparative Prescription Example 1 (Sunscreen Cream) A cream was obtained in the same manner as in Prescription Example 1 except that 2.0% of fine particle titanium oxide (average particle size 0.035 μm) was added instead of glycine zinc used in Prescription Example 1. ..

Comparative prescription example 2 (sunscreen emulsion) Instead of the glycine zinc used in prescription example 2, comparative prescription example 1
An emulsion was obtained in the same manner as in Prescription Example 2 except that 1.0% of the same fine particle titanium oxide as used in Example 1 was blended.

Comparative prescription example 3 (sunscreen lotion) Same as prescription example 3 except that 1.0% of the same particulate titanium oxide as used in comparative prescription example 1 was used instead of zinc glutamate used in prescription example 3. I got lotion.

Comparative Prescription Example 4 (Sunscreen Liquid Foundation) Instead of the glycine zinc used in Prescription Example 4, Comparative Prescription Example 1
A liquid foundation was obtained in the same manner as in Formulation Example 4 except that 5.0% of the same fine particle titanium oxide as used in Example 1 was blended.

Comparative prescription example 5 (sunscreen powder foundation) The same as prescription example 5 except that 10.0% of the same fine particle titanium oxide as used in comparative prescription example 1 was blended in place of the zinc glutamate used in prescription example 5. I got a powder foundation.

The cosmetics obtained in Formulation Examples 1-5 and Comparative Formulation Examples 1-5 were subjected to the following tests.

Test Example 1 (Sunscreen Index) The cosmetics obtained in Formulation Examples 1 to 3 and Comparative Formulation Examples 1 to 3 were uniformly mixed with a solvent (ethanol or water) to 0.2 mg / ml. After dispersion, the spectrum in the UV-B region with a wavelength of 290 to 320 nm was measured with a spectrophotometer (Hitachi U-3200 manufactured by Hitachi, Ltd.) using a 1 cm quartz square cell. The sunscreen index was calculated from the area value by the following formula: sunscreen index = 0.243 x area value + 1.

Formulation Examples 4 and 5 and Comparative Formulation Examples 4 and 5
Each of the cosmetics obtained was diluted with 5 times the amount of water, then uniformly applied to a quartz plate using a 10 μ applicator and dried sufficiently, and the spectrum in the UV-B region with a wavelength of 290 to 320 nm was measured by the above-mentioned spectroscopy. It was measured with a photometer. The sunscreen index was calculated from the area value by the same formula as described above. The results are shown in Table 1.

[0036]

[Table 1]

Further, Formulation Examples 1-5 and Comparative Formulation Examples 1-
For the cosmetics obtained in No. 5, the following monitor tests were conducted.

Example 1 (Sunscreen Effect) On a sunny day in June, a panel of 10 healthy panelists, 5 healthy men and 5 females aged 25 to 40, and cosmetics were randomly selected on a sunny day. ² mg per 1 cm ² was applied. After irradiating the skin with sunlight for 2 hours, the cosmetics were wiped off, and the degree of sunburn was visually evaluated on the basis of the following criteria with respect to the intensity of erythema and the effect of preventing melanin pigmentation. The results are shown in Table 2. The evaluations in Table 2 are comprehensive evaluations of 10 persons.

[Erythema intensity] A: Very weak B: Weak C: Strongly strong D: Strong [Melanin pigmentation preventing effect] A: Very good B: Good C: Slightly bad D: Bad

[0040]

[Table 2]

Example 2 (Feeling of Use) Panelists of 30 randomly selected healthy women aged 30 to 50 were asked to use each cosmetic as usual, and prescription examples 1 to 3 were used.
For the cosmetics obtained in Comparative Prescription Examples 1 to 3, page 6 shown in Table 3, Prescription Examples 4, 5 and Comparative Prescription Examples 4, 5
With respect to the cosmetics obtained in the above, the 7 items shown in Table 4 were evaluated in 5 grades based on the following criteria.
The results are shown in Tables 3 and 4. The evaluations in Tables 3 and 4 are the average values of the evaluation points of 30 persons.

[Usage] 5: Very good 4: Good 3: Normal 2: Slightly bad 1: Bad

[0043]

[Table 3]

[0044]

[Table 4]

As shown in Tables 1 to 4, it was found that the effect of the cosmetics of the present invention was more than that of the conventional cosmetics as shown in the comparative formulation examples.

As a result of the monitor test of Examples 1 and 2, none of them complained of abnormality on the skin.

[0047]

EFFECT OF THE INVENTION The cosmetic of the present invention containing an amino acid metal salt has not only a high UV blocking effect, but also a natural finish with no whiteness and a high transparency, and a good usability. Play.

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[Procedure amendment]

[Submission date] November 18, 1991

[Procedure Amendment 1]

[Document name to be amended] Statement

[Name of item to be corrected] 0003

[Correction method] Change

[Correction content]

[0003]

In view of the above points, the inventors of the present invention have conducted extensive studies to solve the above problems, and as a result, by adding an amino acid metal salt as an active ingredient, an excellent ultraviolet blocking effect was obtained. not only have, in high natural finish of whiteness is no clarity, and is a good feeling of use cosmetic gills found Rukoto, which resulted in the completion of the present invention.

[Procedure Amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0007

[Correction method] Change

[Correction content]

[0007] As the amino acids metal salts, aliphatic amino acids, may be any of aromatic amino or heterocyclic group amino acids. For example, monoaminomonocarboxylic acids such as glycine, alanine, and valine; oxyamino acids such as serine and threonine; sulfur-containing amino acids such as cysteine and methionion; monoaminodicarboxylic acids such as aspartic acid and glutamic acid; diaminomonocarboxylic acids such as lysine. Aliphatic amino acids such as are preferred examples. Among these, glycine, alanine, and glutamic acid are particularly preferable in view of the appearance color of powder, stability, and feeling of use.

[Procedure 3]

[Document name to be amended] Statement

[Correction target item name] 0016

[Correction method] Change

[Correction content]

[0016] As the preservative antioxidants example, parahydroxybenzoate ester, dehydroacetic acid (and its salts), sorbic acid (and salts thereof), lysozyme chloride, dibutyl hydroxy toluene and butyl hydroxy anisole and the like ..

Claims (5)

[Claims] 1. A cosmetic comprising an amino acid metal salt as an active ingredient. 2. The amount of the amino acid metal salt compounded is the total amount of the cosmetic.
The cosmetic according to claim 1, which is 0.01 to 95% by weight. 3. The particle size of the amino acid metal salt is 0.01 to 50 μm.
The cosmetic according to claim 1, wherein 4. The cosmetic according to claim 1, wherein the amino acid metal salt is zinc glycine. 5. The cosmetic according to claim 1, wherein the amino acid metal salt is zinc glutamate.