JPH06312902A - Bensultap solid preparation - Google Patents

Abstract

PURPOSE:To obtain a stable bensultap solid preparation mixed with calcium carbonate as an extender. CONSTITUTION:An agrichemical solid preparation contains 1.0-30.0wt.%, preferably 30-10.0wt.% of bensultap and 60-90.wt.%, preferably 75-85wt.% of calcium carbonate as an extender instead of clay. By using calcium carbonate as the extender, bensultap can be mixed with silafluofen or validamycin A, which can not be stably blended in the case of using clay. The solid preparation can optionally be blended with auxiliary components such as dispersant, spreader, wetting agent, thickening agent, consolidation inhibitor, flocculant, binder and oxidation inhibitor.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a stabilized bensultap solid formulation. The formulation of the present invention is used in the field of agriculture and horticulture for the purpose of controlling pests.

[0002]

BACKGROUND OF THE INVENTION Bensultap is low toxic to human livestock and fish, and has an excellent insecticidal action against harmful insects of rice, wheat, grains such as potatoes, vegetables such as cabbage and cabbage, tea, ornamental plants and other useful plants. It is commercially available as a solid preparation such as powder, granules, etc. (Agricultural Chemical Handbook, 1992 edition, published by Japan Plant Protection Association).

Bensultap is chemically known to be unstable due to hydrolysis under alkaline conditions (The Pesticide Manual page 62), and calcium carbonate is known to be used in the agrochemical field. However, the use of alkaline calcium carbonate as a bulking agent in the conventional production of a bensultap-containing solid preparation has been repelled, and no attempt has been made to use it. Conventionally, clay showing weak acidity has been exclusively used as a bulking agent for bensultap solid preparations.

[0004]

However, since clay is a mineral obtained from nature, its physical and chemical properties (for example, particle size, water content, pH, etc.) fluctuate greatly depending on the place and time, and it has a constant quality. There are often difficulties in providing solid formulations. Furthermore, even if it is attempted to further mix Silafluofen, which is another insecticidal component, with a bensultap solid-type formulation using clay as a filler, such a mixed solid-type formulation has commercial value because Silafluofen is remarkably easily decomposed by clay. There wasn't.

The present inventors have studied using various extenders, excipients, stabilizers and the like that can be used for solid preparations in the field of agriculture and horticulture, and as a result, as described above, bensultap decomposed under alkaline conditions. It is known that even though calcium carbonate is alkaline, Bensultap does not undergo surprisingly substantial decomposition even when the two are mixed, and solid form using clay as an extender. It was found to be as stable as the formulation. Furthermore, the present inventors have found that in a formulation in which silafluofen is further added to a bensultap solid-type formulation in which calcium carbonate is used as a bulking agent instead of clay, the degradation of silafluofene can be substantially prevented.

That is, it was found that a mixture of bensultap and silafluofene can be prepared for the first time by using calcium carbonate as a bulking agent.

[0007]

Means for Solving the Problems The solid preparation of the present invention is
Usually, it is a powder or granule, and includes so-called powder DL and fine powder F.

The chemical name of bensultap used in the solid preparation of the present invention is S, S '-[2- (dimethylamino).
Trimethylene] bis-benzenethiosulfonate, which is easily produced according to a known method (literature name: JP-B-45-18847).

The content ratio of bensultap in the solid production of the present invention is usually about 1.0 to 30.0% by weight, more preferably about 3.0 to 10.0% by weight.

The amount of calcium carbonate used as a bulking agent is usually about 60 to 90% by weight, more preferably about 7%.
5 to 85% by weight.

The solid preparation of the present invention may contain other agrochemical active ingredients in addition to bensultap. Such pesticidal active ingredients are preferably insecticidal ingredients and bactericidal ingredients, and specific examples thereof include silafluofene and validamycin A. Although their content cannot be generally stated, it is usually about 0.1 to 10.0% by weight based on the whole preparation,
It is preferably about 0.3 to 5.0% by weight.

In addition to these components, auxiliary components such as a dispersant, a spreading agent, a wetting agent, a thickening agent, an anti-caking agent, a coagulant, a binder and an antioxidant may be added, if necessary. Good.

As the surface active agent used as a dispersant, a spreading agent, a wetting agent or a penetrating agent, a nonionic surface active agent, an anionic surface active agent or the like is used.

Specifically, nonionic surfactant-polyoxyethylene alkylaryl ether (eg,
Neugen EIA 142 (EA-142), manufactured by Dai-ichi Kogyo Seiyaku Co., Ltd. ・ Ethylene oxide and propylene oxide block copolymer (eg, Newpol PE-64, manufactured by Sanyo Kasei) ・ Polyoxyethylene nonylphenyl ether (eg, N)
P-85, manufactured by Takemoto Yushi Co., Ltd.-Anionic surfactant-Polycarboxylic acid type surfactant (eg, Toxanone GR-
30: Trademark: Sanyo Kasei) ・ Dialkylsulfosuccinic acid ester sodium salt (eg, Neocor SW-C, manufactured by Dai-ichi Kogyo Seiyaku) ・ Polyoxyethylene distyrenated phenyl ether sulfate ammonium salt (eg, Dixsol 60)
A, Dixsol WK, manufactured by Dai-ichi Kogyo Seiyaku), sodium alkylnaphthalene sulfonate (eg, Newcalgen BX-C, manufactured by Takemoto Yushi Co., Ltd.), sodium lignin sulfonate, potassium lignin sulfonate.

This surfactant is usually used in an amount of 0% of the total composition.
It is used in the range of -30 wt%, preferably 0-20 wt%.

As the flow aid, a PAP aid (eg, isopropyl acid phosphate), talc and the like are used as required.

The flow aid is generally 0 to 0 of the entire composition.
It is used in the range of 20% by weight, preferably 0-10% by weight.

As anticaking agents, white carbon,
Diatomaceous earth, magnesium stearate, aluminum oxide, titanium dioxide and the like are used as necessary.

The anti-caking agent is usually added to the composition in an amount of 0.
It is used in the range of -50% by weight, preferably 0-20% by weight.

As the coagulant, liquid paraffin, ethylene glycol, diethylene glycol, triethylene glycol, isobutylene polymer (eg, IP solvent-
2835: Trademark; manufactured by Idemitsu Petrochemical Co., Ltd., etc. are used as necessary.

The aggregating agent is usually 0 to 2 of the entire composition.
It is used in an amount of 0% by weight, preferably 0.2 to 10% by weight.

As the binder, carboxymethyl cellulose sodium salt (eg, Serogen 7A: trademark; manufactured by Dai-ichi Kogyo Seiyaku Co., Ltd.), dextrin, pregelatinized starch, polyvinyl alcohol, sodium lignin sulfonate, potassium lignin sulfonate, etc. may be used, if necessary. Used.

The binder is usually 0 to 3 of the total composition.
It is used in an amount of 0% by weight, preferably 0.2 to 10% by weight.

Silafluofen, which can be blended with bensultap according to the present invention, can be added after being dissolved in a suitable solvent.

Alkylbenzene is preferred as a suitable solvent. Specifically, butylbenzene, dodecylbenzene, pentadecylbenzene, alkene 20T (Nippon Petroleum Detergent; mixture of C ₁₂ alkyl φ to C ₁₉ alkyl φ, φ
Indicates benzene. The same shall apply hereinafter), Alken 56N (the same;
C ₉ alkyl φ to C ₁₆ alkyl φ mixture), alkene 100P (same; mixture of C ₁₂ alkyl φ to C ₂₃ alkyl φ), Hisol F (same; mixture of C ₅ alkyl φ to C ₈ alkyl φ) and the like. Used conveniently.

The addition ratio of these solvents is 1 with respect to the whole preparation.
It is about 10 to 10% by weight, preferably about 4 to 8% by weight.

As described above, calcium carbonate is used as a bulking agent for the solid preparation of the present invention, but if desired, other bulking agents, carriers or excipients may be used together with calcium carbonate. As such, mineral powders such as clays (eg, finely powdered clay), talcs (eg, talc powder, wax stone powder, etc.), silicas (eg, diatomaceous earth powder, mica powder, etc.), for example, In addition to vegetable powders such as soybean powder, tobacco powder, wheat flour and wood powder, sulfur powder, urea powder and the like are used alone or in combination of two or more. The amount of such a filler other than calcium carbonate used is about 0 to 30 with respect to the entire preparation.
It is about 0 to 20 parts by weight, preferably about 0 to 20 parts by weight.

Dusts or granules can be easily produced according to a method known per se using the above components as raw materials.

Dust can be produced by thoroughly mixing the above components and pulverizing the mixture with a pulverizer such as a hammer mill, a ball mill or a pin mill.

Granules can be produced by mixing the above components well with water, granulating with, for example, an extrusion granulator, and drying. Weight of water used is 10
About 5 to 15 parts by weight, preferably about 10 parts by weight, relative to 0 parts by weight
It is about 13 parts by weight.

[0031]

EXAMPLES The present invention will be described in detail below with reference to examples and test examples. All "parts" represent parts by weight.

Example 1 Bensultap 4 parts, Serogen 7A 3 parts, NP-85
0.5 part and 85.5 parts of calcium carbonate are put into a kneader and mixed well. To this, 12 parts of water is added and kneaded, then granulated and dried to obtain 93 parts of core particles containing bensultap. 1 part of Silafluofen and 56N Alkene
A solution of 6 parts was impregnated, mixed for about 30 minutes at room temperature and sufficiently adsorbed to obtain a bensultap-silafluofen mixed granule.

Example 2 75.95 parts of calcium carbonate, clay for DL powder 15.
2 parts, white carbon 0.75 parts, zinc oxide 5.0
And 2.0 parts of Bensultap are mixed well. To this, a mixed solution of 0.2 part of dolileth C, 0.4 part of tall oil fatty acid, and 0.5 part of silafluofen was added, mixed well, and then pulverized to be mixed with Bensultap / silafluofen powder D
L was obtained.

Example 3 75.65 parts of calcium carbonate, clay for DL powder 15.
1 part, white carbon 0.75 part, zinc oxide 5.0
Part, bensultap 2.0 parts, validamycin A0.3
And 0.1 part of potassium sorbate are mixed well. To this, a mixed solution of 0.2 part of dolireth C, 0.4 part of tall oil fatty acid, and 0.5 part of silafluofene was added, mixed well, and then pulverized to obtain a bensultap-silafluofen-validamycin A mixed powder DL.

Reference Example 1 Bensultap 4 parts, Serogen 7A 3 parts, NP-85
Add 0.5 parts and 85.5 parts of clay for granules to the kneader,
Mix well. An appropriate amount of water is added to this, and the mixture is kneaded, then granulated and dried to obtain 93 parts of neutrophil-containing nuclei. The core particles were impregnated with a solution of 1 part of silafluofene and 6 parts of alkene 56N to obtain a bensultap-silafluofen mixed granule.

Reference Example 2 91.15 parts of clay for DL powder, white carbon 0.10 parts
75 parts, 5.0 parts of zinc oxide and 2.0 parts of bensultap are mixed well. To this, a mixed solution of 0.2 part of dolileth C, 0.4 part of tall oil fatty acid, and 0.5 part of silafluofen was added, mixed well, and then pulverized to obtain a bensultap-silafluofen mixed powder DL.

Test Example 1 10 g of a sample was placed in a glass bottle, tightly stoppered, and stored in a thermostat at 40 ° C., and the storage stability of the active ingredient after 1 month and 3 months was examined. The test results are shown below.

[0038]

[Table 1]

From the above, it is clear that bensultap is stable as in the case of using it as a clay extender, even though calcium carbonate is used as the extender. Other ingredients, Silafluofen, Validamycin A
Is also stable.

[0040]

INDUSTRIAL APPLICABILITY Bensultap in the solid preparation of bensultap prepared by using alkaline calcium carbonate as a bulking agent is unexpectedly stable. Also, by using calcium carbonate as a bulking agent, a mixed preparation of bensultap and silafluofene became possible for the first time.

Claims (3)

[Claims] 1. A pesticide solid formulation comprising bensultap and calcium carbonate. 2. The solid pesticide formulation according to claim 1, which further contains silafluofen as the pesticidal active ingredient. 3. The solid pesticide preparation according to claim 2, which further contains validamycin A as the pesticide active ingredient.