JPH06321728A - Scrubbing cosmetic - Google Patents

Abstract

PURPOSE:To obtain a scrubbing cosmetic having good effect of removing stain of skin and aged corneal cell, free from irritation to skin and excellent in stability. CONSTITUTION:Water suspension of beta-1,3-glucan is made to gel by gradually adding the glucan water suspension to an oily base heated to 80-90 deg.C under stirring and cooled to ambient temperature under stirring to afford a gel globbular body. In this time, a water soluble substance of germicide, humectant, etc., stable to heat can be included or a water soluble substance such as humectant or antiinflammatory agent and/or enzyme is included in the beta-1,3-glucan gel and crushed and granulated to give the gel globular body. The globular body is separated and collected and dispersed into cosmetic as a scrubbing agent. The resultant cosmetic is free from irritation to skin, can favorably remove aged corneal cell and also exhibits good cleansing effect by action of included water soluble substance and enzyme.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION The present invention has a spherical shape and is highly elastic,
The present invention relates to a scrub cosmetic having a good effect by blending a gel spherical body composed of β-1,3-glucan that is gentle on skin and excellent in stability as a scrub agent.

[0002]

2. Description of the Related Art In recent years, a lot of scrub cosmetics containing a scrub agent have been used for the purpose of removing dirt and aging keratinocytes of the skin and promoting metabolism by giving an appropriate stimulus to the skin. There is.

As the above-mentioned scrubbing agents, natural ones include apricot carpel and almond seeds, plant carcass and seeds, crab shells, egg shells and the like, and synthetic ones nylon powder, polyethylene powder, Crystalline cellulose powder or the like is used.

[0004]

However, natural scrubbing agents have quality control problems such as microbial contamination and it is difficult to maintain a certain level of quality, and the scrubbing agent has a different shape. As a rule, when used in combination with scrub cosmetics, there was a risk of damaging the skin.

On the other hand, in a synthetic scrubbing agent, polyethylene powder, for example, can be formed into a spherical shape, but it has a high hardness and also has a strong irritation to the skin. The crystalline cellulose powder is difficult to be spherical and has a problem in stability in cosmetics.

[0006] Therefore, the conventional scrub cosmetics containing the above-mentioned scrub agents have a risk of causing skin symptoms accompanied by pigmentation similar to abrasion melasma due to nylon towels due to excessive use, and are also used. It was sometimes painful and difficult to use, especially for consumers with weak skin.

The present invention solves the above problems and provides a scrub cosmetic which has a good effect of removing dirt and keratinous cells from the skin, has a mild action on the skin, is not irritating, and is excellent in stability. With the goal.

[0008]

[Means for Solving the Problems] In order to solve the above-mentioned problems, the present inventor has studied a scrubbing agent having no skin irritation and excellent stability. As a result, they have found that a gel spherical body produced from β-1,3-glucan is optimal for achieving the object of the present invention, and completed the present invention.

Β-1,3-glucan is a heat-coagulable polysaccharide produced by bacteria, and has a property of forming a gel by forming a three-dimensional network structure by the formation of a hydrophobic bond when heated at a high temperature. In addition, a gel is formed by desolvation, neutralization of an alkaline solution, and crosslinking by addition of metal ions. At that time, a bactericidal agent, an antibacterial agent, a water-soluble substance or an enzyme having a good action effect on the skin such as moisturizing property and anti-inflammatory property can be included.

Therefore, the scrubbing agent used in the present invention can be prepared as follows. That is, β-1,3
An aqueous suspension of glucan is gradually added to an oily base heated to 80 to 90 ° C with stirring to cause gelation, and then cooled to room temperature with stirring while being prepared. The β-1,3-glucan gel thus prepared becomes a true spherical body. At this time, the particle diameter of the gel spherical body to be produced can be controlled by adjusting the stirring speed. This gel sphere dispersion is allowed to stand for a while to precipitate the gel sphere, which is taken out as a scrubbing agent.

As the oily base, hydrocarbons such as liquid paraffin and squalane, vegetable oils such as castor oil, olive oil and jojoba oil, and silicone oils which are liquid at room temperature are used.

When β-1,3-glucan is added to an aqueous solution in which various water-soluble substances are dissolved to form an aqueous suspension and then gelled, β-1,3-glucan gel spherical particles are formed. A scrubbing agent in which a water-soluble substance is incorporated and the water-soluble substance is included can be obtained. In this case, heat-stable water-soluble substances such as amino acids and polyhydric alcohols such as glycerin are used.

Further, an alkaline solution of β-1,3-glucan is mixed with an aqueous solution containing a water-soluble substance and / or an enzyme,
It can be dropped into an aqueous solution of a metal salt such as calcium chloride to form a β-1,3-glucan gel encapsulating these, and this can be crushed and granulated to form a spherical body. In this case, as the water-soluble substance, amino acids, polyhydric alcohols such as glycerin, mucopolysaccharides such as hyaluronate and other moisturizers, water-soluble vitamins such as vitamin B group and vitamin C,
Examples thereof include anti-inflammatory agents such as allantoin, and animal or plant water or water-miscible solvent extracts.

As the above-mentioned enzyme, a protein hydrolase which decomposes sebum and waste products which are accumulated on the skin surface and cause dirt on the skin, and a lipid hydrolase such as lipase are preferable.

The scrubbing agent prepared as described above,
Scrub cosmetics are prepared by dispersing and blending with ordinary cleaning cosmetics such as lotion for washing, milky lotion for washing, face-washing cream, washing oil, and jelly for washing. Additives such as polyhydric alcohol such as drum and glycerin, other moisturizers, preservatives, anti-inflammatory agents such as vitamin E and glycyrrhizinate can be blended.

[0016]

[Function] When the scrub cosmetic according to the present invention is applied to the skin and lightly rubbed, the β-1,3-glucan gel spheres dispersed in the cosmetic gently rub the skin to stain or age the skin surface. It exerts the action of adsorbing and removing the keratinocytes that have been removed. At this time, if a water-soluble substance such as sterilizing agent, antibacterial agent or moisturizing agent is included in the scrubbing agent, the water-soluble substance is removed from the gel spherical body by compression with a hand or finger when applying the scrubbing cosmetic. It is released and has its respective effects on the skin. In addition, when an enzyme is included in the gel sphere during preparation of the scrub agent, this action can decompose and wash the dirt on the skin surface due to proteins and lipids.

[0017]

EXAMPLES The present invention will be described in more detail with reference to Examples. First, as Example 1, prescription of cleansing lotion with scrub is shown in Table 1. In Table 1, (1) to (6) were mixed and then heated and dissolved at 70 ° C., which was previously mixed and then heated and dissolved at 70 ° C. and gradually added to (7) to (10) and (13) to emulsify. Let Then cool with stirring, 45 ° C
(12) is added in (3), and the mixture is cooled to room temperature and (11) is added and dispersed. Phenoxyethanol and glycerin-encapsulating β-1,3-glucan gel spheroids of (11) are 3% by weight β-1,3-glucan.
Phenoxyethanol and glycerin were dispersed in a glucan aqueous suspension so as to be 5.0% by weight and 10.0% by weight, respectively, and the suspension was added dropwise to liquid paraffin heated to 90 ° C. with stirring.

[Table 1]

Next, as Example 2, the prescription of a transparent lotion containing scrub is shown in Table 2. In Table 2, (1) to (7) and (9) are mixed and dissolved at room temperature, and (8) is dispersed therein. The β-1,3-glucan gel spherical body containing β-glycyrrhizinate dipotassium of (8) was added to a 3% by weight β-1,3-glucan aqueous suspension to give 1
3% by weight aqueous solution of β-glycyrrhizinate dipotassium:
It mixes in 1, and this is dripped with stirring in the liquid paraffin heated at 90 degreeC, and it prepares it.

[Table 2]

Subsequently, as Example 3, Table 3 shows the formulation of a lotion for elbows and knees containing scrub. In Table 3, (1) ~
(8) and (10) are mixed and dissolved at room temperature, and (9) is dispersed therein. (9) β-1,3-glucan gel spheres were mixed with 3% by weight of an oily base (1: 1: 1: 1 mixture of olive oil, soybean oil, jojoba oil, squalane) heated to 90 ° C. β-
It is prepared by dropping a 1,3-glucan aqueous suspension with stirring.

[Table 3]

Finally, as Example 4, the prescription of the scrubbing face-wash cream is shown in Table 4. In Table 4, (8) is added to (12) and heated, and (7) and (9) are added to 70 ° C. (1) to (6), which had been mixed in advance with this and dissolved by heating at 70 ° C, were gradually added with stirring and saponified at 70 ° C. This is cooled with stirring, (10) is added at 45 ° C., and after further cooling, (11) is added and dispersed. Enzyme encapsulation β-1,3 of (11)
-Glucan gel spheres are prepared by mixing and dissolving 1% by weight protease aqueous solution and 1% by weight lipase aqueous solution in an alkaline aqueous solution of β-1,3-glucan, and dropping them into an aqueous calcium chloride solution to give β-1,3. -Prepare by encapsulating the enzyme in a glucan gel.

[Table 4]

In each of the above examples, the irritation when applied to the skin and massaged, the exfoliating effect and the cleaning effect were evaluated. At this time, in each of the examples, β-1,3-glucan gel spherical bodies were replaced with polyethylene powder,
Comparative example 1, comparative example 2, comparative example 3, and comparative example 4 were respectively set. Skin irritation was determined by applying a sample scrub cosmetic to the inner ear of a rabbit, washing or massaging it, and then intravenously injecting a 1% by weight Evans blue solution, and then vascular permeability by physical stimulation of the scrub cosmetic. Was evaluated by evaluating the degree of increase in In addition, the effect of removing stratum corneum is to make a replica of the epidermis with a dental silicone rubber for the site where the sample was applied during the skin irritation evaluation, and observe the degree of stratum corneum removal with a scanning electron microscope. went. On the other hand, the cleaning effect was as follows: oleic acid 28.3% by weight, triolein 15.6% by weight, cholesterol oleate 12.2% by weight, liquid paraffin 2.5% by weight, squalene 2.5% by weight, cholesterol 1.6% by weight. %, Gelatin 7.0% by weight, each sample is applied to a contaminated skin piece prepared by immersing pig skin in a contaminated liquid, and massaged for 2 minutes. Then, the stain remaining on the skin piece is reflected on the surface at 510 nm. The rate was measured and evaluated. The respective results were evaluated according to the evaluation criteria of "-; not recognized, ±; slightly recognized, +; recognized, ++; significantly recognized" and are shown in Table 5.

[Table 5]

As is clear from Table 5, the vascular permeability was slightly increased in Examples 3 and 4, but in each of the Examples of the present invention, the vascular permeability was markedly increased as compared with each Comparative Example. It was confirmed that the increase in permeability was suppressed, and almost no physical irritation to the skin was observed. Further, in any of the Examples, the same or good effect of removing keratinocytes as in each Comparative Example was observed. Furthermore, in Example 4 of the present invention, a particularly good cleaning effect was observed due to the action of the enzyme contained in the scrub agent.

Next, sensory evaluation tests regarding the feeling of use, cleanability and stimulus were conducted on the examples of the present invention. Thirty female panelists aged 20 to 50 were blindly used in each Example and each Comparative Example, and sensory evaluation was performed on the feeling of use as a scrub cosmetic and the feeling of irritation on the skin. The results are shown in Table 6 by the number of panelists who performed each evaluation.

[Table 6]

As is clear from Table 6, in the examples of the present invention, 1/3 to 1/2 of the panelists did not feel any irritation to the skin. Most of the remaining panelists felt subtle even if they felt a stimulus. On the other hand, in all the comparative examples, most of the panelists felt a considerably strong feeling of irritation. In addition, even if no irritation was felt, the polyethylene powder used as the scrubbing agent in the comparative example was a hard powder having a high hardness, so that the comparative example did not provide a good feeling of use. On the other hand, in all the examples of the present invention, a good feeling of use was obtained. Also, with respect to the cleaning property, the examples of the present invention were generally evaluated better than the comparative examples.

Further, all of the examples of the present invention showed good stability, and no alteration or breakage of the scrubbing agent during storage, alteration of the scrubbing cosmetic itself, or appearance change was observed.

[0026]

Industrial Applicability As described above, according to the present invention, it is possible to provide a stable scrub cosmetic which has a good feeling of use, a keratin removing effect and a cleaning effect and which is not irritating to the skin.

Claims (5)

[Claims] 1. A scrub cosmetic, comprising a gel spherical body composed of β-1,3-glucan as a scrub agent. 2. The scrub cosmetic according to claim 1, wherein the gel spherical body composed of β-1,3-glucan exhibits a true spherical shape. 3. The scrub cosmetic according to claim 1 or 2, wherein a heat-stable water-soluble substance is contained in a gel spherical body composed of β-1,3-glucan. 4. The scrub cosmetic according to claim 1, wherein a gel spherical body composed of β-1,3-glucan is encapsulated with a water-soluble substance and / or an enzyme. 5. The enzyme is a protein hydrolase and / or
The scrub cosmetic according to claim 4, which is also a lipid hydrolase.