JPH06506912A - 環状ケタール誘導体 - Google Patents

環状ケタール誘導体

Info

Publication number
JPH06506912A
JPH06506912A JP4502082A JP50208292A JPH06506912A JP H06506912 A JPH06506912 A JP H06506912A JP 4502082 A JP4502082 A JP 4502082A JP 50208292 A JP50208292 A JP 50208292A JP H06506912 A JPH06506912 A JP H06506912A
Authority
JP
Japan
Prior art keywords
formula
compound
tables
group
formulas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4502082A
Other languages
English (en)
Japanese (ja)
Inventor
サイドボトム、フィリップ　ジェームズ
レスター，マイケル　ジョージ
プロコピウ，パナイオティス　アレクサンドロウ
ワトソン，ナイジェル　スティーブン
ビオンディ，ステファノ
ラムゼイ，マイケル　ビンセント　ジョン
リバーモアー，デイビッド　ジョージ　ヒューバート
ロス，バリー　クライブ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919100424A external-priority patent/GB9100424D0/en
Priority claimed from GB919117151A external-priority patent/GB9117151D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JPH06506912A publication Critical patent/JPH06506912A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP4502082A 1991-01-09 1992-01-05 環状ケタール誘導体 Pending JPH06506912A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB919100424A GB9100424D0 (en) 1991-01-09 1991-01-09 Chemical compounds
GB9100424.2 1991-01-09
GB9117151.2 1991-08-07
GB919117151A GB9117151D0 (en) 1991-08-07 1991-08-07 Chemical compounds
PCT/EP1992/000016 WO1992012158A1 (fr) 1991-01-09 1992-01-05 Derives cycliques d'acetal

Publications (1)

Publication Number Publication Date
JPH06506912A true JPH06506912A (ja) 1994-08-04

Family

ID=26298237

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4502082A Pending JPH06506912A (ja) 1991-01-09 1992-01-05 環状ケタール誘導体

Country Status (4)

Country Link
EP (1) EP0639194A1 (fr)
JP (1) JPH06506912A (fr)
AU (1) AU1158292A (fr)
WO (1) WO1992012158A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0569386B1 (fr) * 1991-01-09 1996-09-25 Glaxo Group Limited Derives cycliques pontes d'acetal
US5256689A (en) * 1991-05-10 1993-10-26 Merck & Co., Inc. Cholesterol lowering compounds
MX9202156A (es) * 1991-05-10 1993-08-01 Merck & Co Inc Novedosos compuestos para reducir el colesterol.
US5468771A (en) * 1991-08-07 1995-11-21 Merck & Co., Inc. Cholesterol lowering compound
US5302604A (en) * 1992-03-09 1994-04-12 Merck & Co., Inc. Cholesterol lowering compounds produced by directed biosynthesis
US5294627A (en) * 1992-08-27 1994-03-15 Merck & Co., Inc. Directed biosynthesis of biologically active compounds
US5369125A (en) * 1992-07-17 1994-11-29 Merck & Co., Inc. Cholesterol-lowering agents
US5283256A (en) * 1992-07-22 1994-02-01 Merck & Co., Inc. Cholesterol-lowering agents
US5326783A (en) * 1992-08-25 1994-07-05 Merck & Co., Inc. Cholesterol lowering compounds
US5278320A (en) * 1992-09-11 1994-01-11 Merck & Co., Inc. Cholesterol lowering compounds produced by directed biosynthesis
US5332728A (en) * 1992-11-23 1994-07-26 Bristol-Myers Squibb Company Method for treating a fungal infection
US5447717A (en) * 1993-02-25 1995-09-05 Merck & Co., Inc. Cholesterol-lowering agents
US5712261A (en) * 1993-10-04 1998-01-27 Magnin; David R. Method for preventing or treating hypertriglyceridemia
US5783593A (en) * 1993-11-04 1998-07-21 Abbott Laboratories Inhibitors of squalene synthetase and protein farnesyltransferase
US5631401A (en) * 1994-02-09 1997-05-20 Abbott Laboratories Inhibitors of protein farnesyltransferase and squalene synthase
US5430055A (en) * 1994-04-08 1995-07-04 Pfizer Inc. Inhibitor of squalene synthase

Also Published As

Publication number Publication date
EP0639194A4 (fr) 1993-09-17
AU1158292A (en) 1992-08-17
EP0639194A1 (fr) 1995-02-22
WO1992012158A1 (fr) 1992-07-23

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