JPH07155384A - Implant material and electromagnetic wave heating device - Google Patents

Abstract

PURPOSE:To provide an electromagnetic wave heating device which is capable of effectively heating the deep part of an object to be heated and controlling heating patterns and heating sections and is effective particularly for hyperthermia. CONSTITUTION:This induction heating device has a magnetic field control section 15 formed by deforming a part of a coil of a magnetic pole and a conductor for magnetic field control 16 independent therefrom as an applicator which is formed by embedding the magnetic pole into a casing 18 composed of a dielectric substance and is cooled by a nonconductive cooling liquid. The device utilizes an optimum heating state by changing frequencies in order to realize the electrical resonance inclusive of a system arranged with an auxiliary electrode 21 or an eddy current absorber in place thereof, besides the object 2 to be heated.

Description

Detailed Description of the Invention

The present invention relates to an electromagnetic heating method,
The present invention mainly relates to an electric current control method, an implant material, and a heating device. More specifically, the present invention relates to a method for controlling an eddy current distribution by reducing or increasing a magnetic field irradiation region with respect to the size of a body to be heated in induction heating, and an apparatus for implementing the method. As a method of controlling eddy currents, the property that eddy currents are less likely to pass through the fat layers and biological membranes of the living body is used, and these fat layers and biological membranes are transmitted in the form of a magnetic field to generate and confine eddy currents inside them. The present invention relates to a method and an apparatus for effectively performing local heating. further,
Part of the heating winding is deformed, a current is forcibly passed through a conductor that is independent of the heating winding, and the frequency is controlled to effectively control the eddy current distribution, thereby deep heating. An applicator device for a method of enabling and controlling a heating pattern. Further, the present invention relates to a method of suppressing the heat generation of such a heating applicator and maintaining the characteristics of the core material. Also,
The present invention relates to an implant material for performing local heating in dielectric heating or induction heating, that is, electromagnetic wave heating.

2. Description of the Related Art Conventionally, it has been extremely difficult to control an eddy current generated in a heated body when heating a desired portion of the heated body by induction heating. For this reason, in hyperthermia, that is, in hyperthermia treatment of cancer and the like, how to control the eddy current distribution of the heated body is an important issue, but in reality, sufficient technology has not been established. is there. Further, when a magnetic material such as a ferrite core is used for the induction heating applicator, heat is generated, the original magnetic characteristics are deteriorated, and there is a problem that sufficient heating cannot be performed. In particular, as an implant material used in hyperthermia, there is no effective one that is flexible with respect to internal tissues and has a function of exerting a thermal effect and a drug effect and a function of also having a temperature measurement. Further, the conventional method using a cavity resonator is to heat an object to be heated by confining electromagnetic waves in the cavity.
There are a method of sintering ferrite by using a cavity resonator by microwave and a method of applying a reentrant resonator to a hyperthermia. These are all methods of confining electromagnetic waves in a closed region to cause resonance, and in principle, the resonance frequency is determined by the structural dimensions of the cavity. However, a heating device that emits electromagnetic waves into space and utilizes resonance in an open region for heating has not been considered.

In induction heating, when a magnetic field is applied to a region smaller than the size of the body to be heated by a magnetic pole or the like, the portion of the body to be sandwiched between the opposing magnetic poles hardly generates heat, and its peripheral edge. The eddy current is unevenly distributed in the area and heat is strongly generated in the peripheral portion, and a hot spot called a so-called hot spot occurs. This is because even if the magnetic field distribution is given so that the magnetic pole center part has the maximum irradiation magnetic field, the eddy current of the heated body is small in the part corresponding to the magnetic pole center part and large in the peripheral part. According to this principle, the peripheral portion of the object to be heated can be heated locally or regionally. In this case, when the magnetic pole is gradually increased and the magnetic field is applied using a magnetic pole larger than the size of the heated body, the generation of eddy current is reduced, and if the implant material is embedded in the heated body, the implant Local heating of only the material is possible. When an insulating film is present on the object to be heated, a magnetic field is applied to this and the inside of these to generate an eddy current inside these insulating films to generate an eddy current inside the insulating film. The eddy current control method of confinement enables local heating and area heating. In Hyperthermia,
This insulating film corresponds to a biological film or a fat layer. In addition, it is difficult to control the electric field, the magnetic field, that is, the eddy current in an applicator for dielectric heating, especially induction heating.
In particular, in hyperthermia and the like, hot spots occur, and there is a problem that desired portions and deep portions cannot be sufficiently heated. In the induction heating, the deep portion cannot be sufficiently heated due to the property that the eddy current flows on the surface of the object to be heated, and the heating technique for controlling the heating pattern is limited. One object of the present invention is to solve such a problem. Further, regarding the implant material for dielectric heating, there is a lack of an implant material that is easily adapted to living tissue and an implant material having a heat generation and temperature measurement function, and it is necessary to solve this problem. The present invention solves the problems of deep heating, control of the heating pattern of the object to be heated, and local heating by the method and apparatus described above.

[Means for Solving the Problems] In induction heating, as described above, eddy currents are generated in the peripheral portion of the object to be heated.
When the induction heating method is applied to hyperthermia using implants, it is necessary to eliminate or reduce the generation of unnecessary eddy currents, heat only the implant material, and perform local heating. In order to solve these problems, the present invention pays attention to the property that heat is not generated between the opposed magnetic poles of the heated body even if the central portion of the opposed magnetic pole has a strong magnetic field distribution, and the magnetic field irradiation larger than the size of the heated body is applied. Generation of hot spots on the object to be heated is suppressed by irradiating a magnetic field to the object to be heated by a magnetic pole having an area or a magnetic field irradiating means according to another method with the same principle. The hotspot here is
It is a high-temperature region generated in the object to be heated. That is,
By using the magnetic field irradiation means having a larger magnetic field irradiation area than the object to be heated, hot spots generated on the object to be heated are almost eliminated. However, since the magnetic field extends into the body to be heated, the problem of local heating in hyperthermia or the like is solved by the means that if an implant material for induction heating is buried, only this implant material can generate heat. That is, local heating can be effectively performed by performing implant heating on an object to be heated with an applicator device having an oversized magnetic field irradiation means. When this method is applied to hyperthermia, it is often difficult to construct a magnetic pole or a magnetic field irradiating means that is larger than the human body that is the object to be heated. In order to solve this problem, when a magnetic pole such as a ferrite core is used as the magnetic field irradiating means, a large core, that is, a large magnetic pole is formed by collecting and integrating a large number of small cores and winding a coil around them. Further, it is possible to adopt a means for forming a large core, that is, a large magnetic pole by collecting a large number of coils wound around small individual cores and passing an in-phase current. Based on the above-described configuration principle, unnecessary generation of hot spots in the object to be heated is reduced, and local heating using an implant is possible. Next, when the heated object is heated by a magnetic field irradiating means such as a magnetic pole having a magnetic field irradiation area smaller than the heated object size, the peripheral portion of the heated object area corresponding to this area can be heated. The eddy current can be controlled by means of confining the eddy current in the insulating film forming a larger region. This is an effective means for local heating and area heating in hyperthermia and the like. Next, in order to control the electromagnetic field generated in the object to be heated, in addition to the irradiation electromagnetic field for heat generation with the applicator, either by an integrated circuit with the applicator or by supplying a current to an independent circuit to control the electromagnetic field distribution. Take the means to do.
For example, a coil (winding) for generating a heating magnetic field is wound around a magnetic pole of a magnetic core material, and a part of the coil is wound around a deformed structure,
A method of controlling the magnetic field distribution to the object to be heated, that is, the eddy current is adopted. In addition to partially deforming the coil in this way, a conductor is placed around the heated object completely independently, a current is forced to change the magnetic field distribution forcibly, and the heating pattern is controlled.
A method that enables deep heating may be used. Next, when induction heating is performed by the core using a magnetic material, heat is generated in the core, and the magnetic characteristics of the core deteriorate, so that a sufficient magnetic flux cannot be generated. In order to improve this, the magnetic core is embedded in a dielectric casing, and a fluid such as silicon oil is circulated through the entire core to cool it. Next, a means for changing the heating pattern of the object to be heated and changing the frequency, that is, the wavelength according to the characteristics of the object to be heated in order to achieve deep heating. In particular, in a hyperthermia using a magnetic core, since the body to be heated is a human body, it is difficult to control the heat generation pattern due to individual differences at different frequencies and constant frequencies, and this is the case. It becomes an effective means. Next, the object to be heated corresponds to an electric circuit-like load when viewed from the electromagnetic wave irradiation applicator including an accessory that assists this heating. Therefore, when the system of the applicator, the object to be heated and the accessory device thereof is considered as one equivalent electric circuit, there is an inductance (L), a capacitance (C) and a resistance (R), and so-called L, A resonance circuit of C and R is formed. When this resonance condition is satisfied, the object to be heated reaches the optimum condition and can efficiently generate heat, and the heating pattern can be controlled and the deep portion can be heated. In other words, by selecting the frequency at which the electromagnetic wave emitted from the applicator to the space that is the open area resonates, including the object to be heated and accessories such as auxiliary electrodes that control the current distribution arranged around it, The electrodes and accessories for electromagnetic field control work optimally to control the heating pattern and achieve deep heating. In the example of induction heating, a magnetic field control plate is attached to the front surface of the magnetic pole core or the magnetic field control coil to control the eddy current distribution generated in the heated object. By these means, the deep part can be efficiently heated. Next, the implant material used in hyperthermia and the like has some drawbacks. The present invention employs a means for inserting an implant material into a human body or the like, injecting a fluid implant into a heated site using a syringe or the like without performing a surgical operation and solidifying the implant at a body temperature. Also, in dielectric heating, paying attention to the fact that the fat layer of the human body strongly generates heat, and by injecting this kind of fat into the heating site alone to generate heat, or by mixing a conductive or magnetic material into this kind of fat. , It takes a means to inject heat into the part to be heated to generate heat. Furthermore, a therapeutic drug can be mixed into these to perform combination therapy of hyperthermia and drugs. Of course, the fluid heat generating material is not limited to fat, and any material may be used as long as it is harmless to the living body. In addition, implant materials made of magnetic materials or conductive materials, if the surroundings of the embedded site are conductive like hyperthermia, eddy currents generated in the implant diffuse into the surrounding medium, especially when the implant material is small. I can't heat up. Therefore, a measure is taken to cover these implant materials with an insulating material to enhance the heat storage effect. Next, a shape memory alloy has already been devised as an implant (Showa 60, No. 31357), but like this, it is embedded in a body to be heated and preliminarily shaped so as to be deformed at a predetermined temperature. Is stored, and the temperature is measured using a means for examining the shape that is deformed due to the temperature change due to radiation or electromagnetic waves, such as radiation that passes through the object to be heated, or radiation. In this case, since most of the current shape memory alloys do not change suddenly with respect to temperature changes, the shape memory alloy is housed in a container and a certain force is applied to the shape memory alloy and It is configured such that it maintains a constant shape with respect to changes and that the shape changes greatly when the desired temperature is reached. Then, the change in the shape is measured by radiation such as X-rays or ultrasonic waves from outside the object to be heated to measure whether the temperature is desired. Of course, it is not limited to the shape memory alloy, and any object whose shape changes with temperature such as shape memory plastic or bimetal processed to generate heat may be used. The above-described invention is particularly effective for normal heating and induction heating, for deep heating, local heating, control of heating position and pattern, temperature measurement, and the like, and is particularly effective means for hyperthermia.

By the above means, it is possible to control the eddy current by induction heating, and a device to which the eddy current is applied can be constructed. However, according to the present invention, it becomes easy to heat a desired portion of the heated object.
That is, when irradiating a magnetic field with an applicator having a magnetic field irradiation region smaller than the size of the object to be heated, the peripheral portion of the magnetic field irradiation region can be locally or regionally heated, and especially in the hyperthermia etc., inside the fat layer, biological membrane. It has the effect of being able to generate heat internally. On the contrary,
Generation of eddy current can be reduced by using an applicator having a magnetic field irradiation region having a size larger than that of the object to be heated. In this case, since the magnetic field penetrates into the object to be heated, the use of the induction heating implant material has the effect of locally heating only the implant material. In addition, an implant material that solidifies into a solid state at body temperature is easier to embed in a heated body than a solid implant material that is embedded in a heated body from the beginning. Further, the implant material made of the shape memory alloy has an effect that both heat generation and temperature measurement can be performed at the same time.

DESCRIPTION OF THE PREFERRED EMBODIMENTS The structure of the present invention will be described in detail below with reference to the embodiments shown in the drawings. FIG. 1 shows that a heated body (2) having a size larger than that of the magnetic pole (1) is arranged between the opposing magnetic poles (1),
It is a principle diagram when this is induction-heated. FIG. 2 shows the relationship between the magnetic field distribution (4) and the eddy current density distribution (5) on the magnetic field irradiation surface (3) of the square heated body (2) at this time.
Shown in. As is clear from the figure, the eddy current is maximized at the peripheral edge of the heated object even if the magnetic field distribution that gives the maximum magnetic field at the magnetic pole center is given. Further, FIG. 3 shows a vector diagram visualizing the eddy current density on the magnetic field irradiation surface (3). The strength of the eddy current is shown in a relationship proportional to the vector length (6). When a magnetic field is applied to an area smaller than the size of the object to be heated in this way, the diamagnetic current acts on the vicinity of the center of the object to be heated and the peripheral part of the object is strongly heated to generate a hot spot. Eddy current can be controlled according to this principle. That is, when the magnetic field irradiation area of the object to be heated is increased, that is, the sectional size of the magnetic pole (1) is increased, the occurrence of hot spots is reduced.
However, since the magnetic field is also transmitted through the object to be heated, if the implant material is embedded in the object to be heated, only the implant material can be locally heated without generating hot spots due to eddy currents. FIG. 4 shows an embodiment of the present invention in which heating is performed by the magnetic pole (1) having a magnetic field irradiation area of a size smaller than that of the object (2) to be heated. This figure shows an example of application to a hiberthermia. Spherical object to be heated (2)
Is composed of a fat layer (8) in addition to the muscle medium (7) as shown in FIG. In this case, an eddy current is generated inside the fat layer (8) by the magnetic field transmitted through the fat layer (8). That is, a heating region (9) due to an eddy current as shown in the sectional view of FIG. 5 is obtained by cutting the spherical heated body (2) of FIG. 4 along the dotted cross section passing through the center of the sphere. The eddy current tends to flow to the peripheral portion of the object to be heated, but is interrupted by the fat layer (8) close to the insulator and the inside of the fat layer can be effectively heated. FIG. 6 shows an example of an induction heating device configured by using a magnetic pole (1) having a magnetic field irradiation area larger than the size of the object to be heated (2). An implant material (10) is embedded in the center of the body to be heated. In FIG. 7, as shown by the broken line in FIG. 6 showing the heat generation on the cut surface passing through the center of the sphere, in this case, the muscle medium (7) and the fat layer (8) hardly generate heat and the implant material ( 10) is selectively heated. FIG. 8 is an embodiment of the applicator for the hyperthermia of the present invention showing the construction method of the large magnetic pole relating to FIG. As shown in the figure, small magnetic poles (11)
Shows an example in which a large magnetic pole is formed by winding a coil (12) in a bundle. FIG. 9 shows an embodiment of a hyperthermia applicator in which small magnetic poles (13) wound with a coil are bundled and integrated to form a large magnetic pole. Although a magnetic pole such as a ferrite core is used as an example of the magnetic field irradiating means in the above embodiments, it goes without saying that a coil or other magnetic field irradiating means may be used. FIG. 10 is a perspective view of an embodiment of the present invention in which the coil (12) is wound around the magnetic core (14) to form an induction heating applicator. A part of the coil is deformed and wound, or a coil is wound around a dielectric cylinder or the like to provide a magnetic field control section (15).
In addition, a magnetic field controlling conductor (16) is arranged around the body (2) to be heated independently of this coil, and a current is forced to flow through the conductor (16) to change the magnetic field distribution of the magnetic poles with the generated magnetic field. The means for controlling the heat generation area by controlling the eddy current distribution generated in the heating element is used. Further, as shown in the figure, an eddy current absorber (24) (see Japanese Patent Application No. 2-403927) is used to absorb unnecessary eddy currents. FIG. 11 shows an embodiment of the present invention in which a deformed magnetic pole (17) made of a magnetic material (see Japanese Patent Application No. 2-403927) is embedded in a casing (18) made of a dielectric material to cool the entire magnetic pole portion. . Inside the casing, a non-conductive cooled liquid such as silicon oil is made to flow in or out through the duct (19) to keep the magnetic pole at a constant temperature. In the known deformed magnetic pole, a water pipe is used for the coil, and a cooling pipe is used to cool the inside of the magnetic pole. There was a problem that it deteriorates and the generated magnetic flux is saturated. In the embodiment shown in FIG. 11, the entire magnetic pole having an open magnetic circuit structure (see Japanese Patent Application No. 1-77607) is placed in a casing for cooling. In this case, the auxiliary electrode (21) (Japanese Patent Application No. 2-403927) attached to the housing (18) through the cushion material (20) and the magnetic field control plate (25) closely attached to the magnetic pole or the housing are attached. ing. FIG. 11 shows an embodiment in which an applicator is constructed by using a coil having the magnetic field control section (15), and an eddy current is controlled by using a magnetic field control lead wire (16). Moreover, in this configuration, the applicator device is configured to drive by setting the frequency so that the entire system including the body to be heated (2), the auxiliary electrode (21), the magnetic field controlling conductor (16), etc. resonates. Is. The conventional invention of this kind of induction heating does not consider the resonance phenomenon of the object to be heated including such an accessory, and therefore, a single fixed frequency applicator is used.
The present invention is particularly effective for hyperthermia, etc., and focuses on the fact that the impedance of the heated body side corresponding to the load changes due to the difference in the size of the human body and the difference in the heating site, and the resonance is changed by changing the frequency each time. Thus, deep induction heating of the object to be heated is enabled, and the heating pattern and heating site are controlled. Further, even when the resonance phenomenon is not used, the frequency is changed in order to change the heating region or heating pattern. Even if the frequency is changed, the frequency does not have to be largely changed unless there is a large change in the heating condition on the heated body side, that is, the load side. In some cases, even if the frequency is constant, the heating device can be configured with respect to slight load side fluctuations. FIG. 12 and FIG. 13 show an implant material using the shape memory alloy (22) (Japanese Utility Model Application No. 31357 of 1960). For example, as shown in the same figure, the shape is memorized in a coil shape. Then, this is put in a stretchable capsule (23), and both ends of the shape memory alloy (22) are fixed by a supporting material that also serves as a heating element such as a conductor or a magnetic material, that is, a heating support material (29). I'll do it. In addition, a liquid (30) may be placed in the capsule in order to make the temperature distribution in the capsule uniform and promote heat generation.
When the desired temperature is reached in this state, the shape memory alloy (2
Since 2) grows with a strong force, as shown in FIG.
The capsule (23) also extends and the shape memory alloy (22) deforms. The temperature can be measured from the expansion / contraction state of the shape memory alloy by putting the object having such a configuration inside the object to be heated, heating the object, and taking an image with, for example, an X-ray from the outside. In this case, the shape memory alloy is not limited to the shape memory fiber or other material, and the capsule (23) may be deformed by temperature. Further, in this case, of course, any light such as radiated light, electromagnetic waves, or ultrasonic waves may be used for shape determination as long as it transmits the object to be heated. Also, the shape memory alloy itself generates heat due to the eddy current, and local heating becomes possible. The above-mentioned invention is a preferred embodiment of the present invention, but is not limited to this, and various modifications can be made without departing from the scope of the invention.

As described above, the present invention relates to an eddy current control method in induction heating, a local heating method using an implant material, and an induction heating device based on these principles. That is, the present invention controls the eddy current distribution by paying attention to the fact that the eddy current distribution differs depending on whether the magnetic field irradiation area is larger or smaller than the maximum area of the section to be heated. In particular, when this method is applied to hyperthermia, there is an effect that local heating or area heating can be performed by skillfully utilizing the fat layer or biological membrane of the living body. In addition, as a method of controlling this eddy current, a design problem of the applicator device is considered by constructing a magnetic field irradiation means having a large magnetic field irradiation area by integrating a plurality of magnetic field irradiation means smaller than the object to be heated. The point is solved. In addition, a part of the coil may be deformed to use the magnetic field generated by the current flowing through this part, or a forced current may be passed around the heated object to change the magnetic field distribution by the generated magnetic field. It provides a method for controlling the eddy current distribution, which has been difficult in the past, and changing the deep heating, heating area, and heating pattern, and is particularly effective for hyperthermia. This is applicable not only to magnetic fields but also to dielectric heating using electric fields. In addition, as a conventional heating method utilizing resonance,
There is a method of firing ferrite using a cavity resonator and a hyperthermia device called a reentrant type. These cause resonance in the form of confining the electromagnetic field in the cavity resonator,
This is how energy concentration occurs. The present invention provides a device capable of effectively heating by a method of radiating an electromagnetic field into a space which is an open region and realizing a resonance state of an object to be heated including accessories. Conventionally, the reproducibility of the heating characteristics is particularly poor due to induction heating, and the deep spots cannot be sufficiently heated to cause hot spots because the fact that resonance is taken by changing the frequency is not taken into consideration. The present invention realizes an effective heat generation state by this discovery. Next, in the method of embedding an implant material composed of a shape memory alloy in the heated object and measuring the temperature by externally photographing the change of this shape with a radiation wave, the lead wire becomes uneasy like a conventional temperature sensor. Can be used for a long time if embedded. This is especially effective for temperature measurement, which is difficult in hyperthermia. In addition, the fluid implant material does not require surgery or the like, and has a utilization effect that it can be easily injected with an instrument such as a syringe. In addition, if a medium such as human body fat that strongly generates heat by dielectric heating is used for the fluid implant material, it is harmless to the human body and has good compatibility. The invention of these methods and devices for carrying out them is particularly large in that it contributes to electromagnetic wave heating in general, including eddy current control of induction heating and dielectric heating, which have been considered to be difficult in the past, especially in hyperthermia for living organisms. Has a noticeable effect.

[Brief description of drawings]

FIG. 1 is a perspective view illustrating the principle of induction heating.

FIG. 2 is data obtained by theoretical calculation showing the relationship between the irradiation magnetic field and eddy current in induction heating.

FIG. 3 is a vector diagram based on theoretical analysis showing an eddy current distribution generated on a surface of a heated magnetic field to be heated.

FIG. 4 is a perspective view of an induction heating method using magnetic poles having a magnetic field irradiation area smaller than a size of a body to be heated according to an embodiment of the present invention.

5 is a sectional view of the object to be heated in FIG.

FIG. 6 is a perspective view of an embodiment of the present invention in which a magnetic pole larger than the size of a heated object is used.

FIG. 7 is a sectional view of the object to be heated in FIG.

FIG. 8 is a perspective view of an embodiment of the present invention in which magnetic poles having small dimensions are bundled and integrated.

FIG. 9 is a perspective view of an embodiment of a magnetic pole of the present invention in which a coil is wound around a magnetic pole having a small size and is integrated.

FIG. 10 is a perspective view of an embodiment of an eddy current control method of the present invention.

FIG. 11 is a perspective view of an embodiment for explaining improvement of heating characteristics by the applicator cooling method and the frequency changing means of the present invention.

FIG. 12 is a cross-sectional view of a shape memory alloy implant material for explaining the temperature measuring method of the present invention.

FIG. 13 is a cross-sectional view showing another example of the shape memory alloy implant material for explaining the temperature measuring method of the present invention.

FIG. 14 is a cross-sectional view showing an example of deformation of the shape memory alloy implant material for explaining the temperature measuring method of the present invention.

[Explanation of symbols]

 1 ... Magnetic pole 2 ... Heated object 3 ... Magnetic field irradiation surface 4 ... Magnetic field distribution 5 ... Eddy current density distribution 6 ... Vector length 7 ... Muscle medium 8 ... Fat Layer 9 ... Heating region 10 ... Implant material 11 ... Small magnetic pole 12 ... Coil 13 ... Small magnetic pole wound with coil 14 ... Magnetic core 15 ... Magnetic field control unit 16 ...・ Magnetic field control conductor 17 ... Deformed magnetic pole 18 ... Case 19 ... Duct 20 ... Cushion material 21 ... Deformation auxiliary electrode 22 ... Shape memory alloy 23 ... Capsule 24 ...・ Eddy current absorber 25 ... Magnetic field control plate 26 ... Exothermic support material 27 ... Liquid

Claims (22)

[Claims] 1. A method of irradiating a magnetic field to a region larger than the size of the object to be heated to reduce hot spots generated in the object to be heated. 2. An applicator using magnetic field irradiation means having a magnetic field irradiation area larger than the size of the object to be heated in order to reduce hot spots generated in the object to be heated, according to the method of claim 1. apparatus. 3. A method for suppressing the generation of hot spots and selectively heating an implant material based on the method and apparatus according to claims (1) and (2). 4. The method and apparatus according to any one of claims (1) to (3), wherein a large number of magnetic field irradiation means smaller than the size of the object to be heated are used as the magnetic field irradiation means for reducing hot spots. An applicator configured to have a larger magnetic field irradiation area than the heating body. 5. A hyperthermia device using the applicator according to claim 4. 6. A magnetic field is applied to an area smaller than the size of the object to be heated to positively utilize the eddy current generated in the peripheral portion of the object to be heated and the current insulating layer, thereby forming a heat generating area inside the insulating layer. Heating method to confine. 7. A hyperthermia device constructed according to the method of claim 6. 8. A method of controlling an eddy current, which utilizes a biological film made of fat or protein to irradiate a magnetic field inside the biological film to generate an eddy current and to confine the eddy current in the biological film. 9. A hyperthermia device based on the method of claim 8. 10. A hyperthermia device comprising a large number of small magnetic field irradiating means that are integrated to form an applicator. 11. An applicator device comprising a coil for irradiating a magnetic field for heating an object to be heated and a coil for controlling a magnetic field, that is, an eddy current of the object to be heated, as an integrated structure. 12. An applicator device, characterized in that a forced current is passed through a conductor independent of a heating coil in order to control the eddy current distribution of a heated object. 13. An applicator device for induction heating, characterized in that, in order to suppress heat generation, a coil-wound core is embedded in a casing capable of refluxing a non-conductive fluid. 14. A heating device configured to perform deep heating by changing the electromagnetic field irradiation frequency according to the size and characteristics of the object to be heated to control the heat generation pattern of the object to be heated. 15. An electromagnetic wave irradiation system, an object to be heated, and an accessory for heating are considered as an equivalent electric circuit, and the electric resonance of this entire circuit system is used to control the heat generation pattern of the object to be heated. Among those that perform deep heating, a heating device that has an open structure without a shielding structure. 16. A hyperthermia device based on the configurations of claims 11 to 15. 17. A fluid implant material composed of a substance harmless to a living body, which is solidified at body temperature when injected into a living body and can be heated by electromagnetic wave irradiation. 18. A fat implant material, characterized in that harmless fat is injected into a living body that generates heat due to dielectric heating, and the fat is heated. 19. An implant material obtained by mixing a drug with the implant material according to claim 17 or 18 so as to have a function of fever and a drug effect. 20. An implant material for induction heating, characterized in that a magnetic material is subjected to conductive plating and covered with an insulating material to enhance heat storage. 21. The implant material according to claim 20, wherein the magnetic material itself is covered with an insulating material to enhance the heat storage effect. 22. A shape memory alloy is memorized so that the temperature changes at a desired temperature, and the shape memory alloy is embedded in a body to be heated, and the temperature change is irradiated with a radiation wave that passes through the body to be heated.
A temperature measurement method that examines changes in the shape to make a decision.