JPH07188042A - Hot compress - Google Patents

Abstract

(57) [Summary] [Purpose] To provide a hot poultice which is highly effective, completely safe for the human body, and easy to use. [Structure] Smashed germinated rice, rice or germinated rice extract, rice or germinated rice hydrolyzed with enzymatic decomposition or koji, rice or germinated rice are extracted Prior to the extraction, at the same time as or after the extraction, those subjected to enzymatic decomposition or koji, the extract of rice or sprouted rice or those subjected to enzymatic decomposition or koji, were subjected to alcohol fermentation or organic acid fermentation. What was done, the above-mentioned each as it is, or a hot compress containing the same.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a warm poultice which is characterized by using rice or sprouted rice and has an effect of increasing temperature and improving blood circulation such as vasodilation.

[0002]

2. Description of the Related Art Conventionally, cold limbs and stiff shoulders due to poor blood circulation have been important problems. In addition to this, recently, from a healthy physical activity as in the past, blood circulation is caused due to stress, etc., such as uncomfortable posture, continuous work, deterioration of living environment such as cooling, air pollution, etc. There are more and more health problems due to worsening. In order to solve these problems, hot compresses that use hot water have been used in the past for extreme ones. However, these are not often used because they are troublesome, their effects are deteriorated over time, and the skin is sore by continuous use.

Therefore, hot compresses containing easily usable camphor, menthol, etc. as active ingredients, as well as warm compresses containing crude drug extracts such as capsicum tincture, have been used. However, in the case of seeking the effect by mixing the isolated substances, the effect is recognized during use because the direct effect is exerted,
After the discontinuation of use, the effect became extremely insignificant and not a fundamental improvement. In addition, although it is effective, it may cause irritation such as itch on the skin, or a rash may appear or redness and swelling may become severe. Also,
Some crude drug ingredients are used as raw materials to improve the constitution and have a gradual effect, but because the raw materials are not stable or cannot be easily manufactured,
At present, it is used only in a limited field.

[0004]

As described above, there are rapidly increasing opportunities to use hot compresses having an effect of improving blood circulation such as a vasodilator effect. In spite of the rapid increase in the use opportunities, safe and effective hot compresses have not been developed yet. Therefore, an object of the present invention is to provide a hot compress which is highly effective, completely safe for the human body, and easy to use.

[0005]

[Means for Solving the Problems] From the viewpoint of animal and plant harmony, the present inventors have conducted research on various plant components centering on rice, which is a staple food. In the process, it has become clear that rice has many unpredictable possibilities and effects. Therefore, we have conducted comprehensive research on the utilization of rice with the theme of rice, which is used as a staple food and proved to have the highest safety. As one of the themes, we have earnestly studied hot compresses from rice.
In the process, the present inventors invented a hot compress for rice obtained by extracting rice with water or organic solvent (Japanese Patent Application No. 4-145034). But cheaper from rice,
The present invention has been completed by finding a more effective warm poultice. That is, the present invention relates to a hot poultice which has an effect of improving safe blood circulation easily and inexpensively by using rice or a germinated product of rice.

[0006] In the present invention, the components having a hot compress effect contained in rice and germinated rice have not yet been clarified, but rice and germinated rice treated as described below are warm compresses. It turned out to be effective. Sprouted crushed rice as it is or containing it. Rice or germinated rice extract as it is or containing it. Enzyme-decomposed or hydrolyzed rice hydrolyzed as it is, or containing it. When extracting rice or sprouted rice, the one that has been subjected to enzymatic decomposition or koji before or at the same time as or after the extraction is used as it is or containing it. An extract of rice or germinated rice or a product of enzymatic decomposition or koji which has been subjected to alcohol fermentation or organic acid fermentation as it is or containing it.

The rice used in the present invention is Japonica,
Regardless of indica rice, it refers to non-glutinous rice, brown rice such as sticky rice, and white rice, regardless of variety and type. Further, 92% or more of red rice bran or 92% or less of white rice bran, which appears during whitening, may be used, which is inexpensive and economical. Also,
Germinated rice is used. In addition, since the active ingredient is stable to heat and light, the above raw materials are dipping, steaming, roasting (all sand roasting, net roasting, hot air roasting, etc.),
The raw material treatment such as steam roasting, surface modification such as freeze-drying, photo-modification such as UV irradiation, pressure roasting such as Patrice, and frying may be performed, and the effect was not changed. Although rice and germinated rice are effective as they are, they are preferably crushed and used from the viewpoint of practical use. In order to pulverize the rice and the sprouted rice into powder, a pulverizer or a rice mill may be used and a general method may be used.

In the case of germinating rice, germinated rice is soaked in water or sprayed with water to germinate. The temperature for germination is 5 to 70 ° C. However, as long as it germinates,
Temperature and time do not matter. Further, when there is a risk of water spoiling during germination, it is preferable to replace the water so that it does not spoil, or to perform some kind of preservative. Here, germination refers to everything from just before germination to germinated ones.
The germinated rice is washed well before use. At this time, it may be dried before use. When extracting rice or sprouted rice, or subjecting it to enzymatic decomposition or koji, the raw material rice is pulverized into granules or powder to increase the surface area, resulting in higher efficiency. Although it is not necessary to grind, in this case, it takes a long time to decompose and extract the rice tissue.

When water or sprouted rice is extracted with water,
High extraction temperature is efficient, but extraction can be sufficiently performed even at low temperature. However, in the case of a low temperature of 40 ° C. or lower, it is desirable to make PH acidic or alkaline, or add a preservative or alcohol to treat the rice so that it does not spoil. The extraction time may be long or short as long as the active ingredient can be extracted, and may be determined depending on the extraction temperature. The extraction may be carried out under pressure, at normal pressure, or under reduced pressure. In the case of water extraction, the most problematic is the gelatinization phenomenon. If it becomes pasty, not only the extraction efficiency will deteriorate, but it will be extremely difficult in actual work.
In order to prevent this, the reaction may be carried out by adding amylase or acidification may be carried out with hydrochloric acid or the like to cut the starch. By using this method, it can be sufficiently solved and there is no problem in practice.

Since the active ingredient in the extract is stable to acid and alkali, it is also effective to carry out acid decomposition extraction or alkali decomposition extraction. In this case, neutralization and desalting are performed if necessary. Also when extracting with an organic solvent, it is desirable to pulverize or pulverize rice as much as possible before extracting. The organic solvent may be a general organic solvent such as alcohol, acetone, n-hexane and methanol, but those harmful to the human body are preferably safe because it is necessary to completely remove the solvent after extraction. In addition, rice or germinated rice may be enzymatically decomposed or koji may be allowed to act. The term "enzymatic degradation" as used herein refers to the action of one or more enzymes that act on rice, such as starch degrading enzymes, proteolytic enzymes, lipolytic enzymes, fiber degrading enzymes, lignin degrading enzymes, and pectin degrading enzymes. The type of koji mold and the variety and type of rice as koji do not matter.

Further, in carrying out the above-mentioned extraction, the above-mentioned enzymatic decomposition and koji may be applied before the extraction, at the same time as the extraction, or after the extraction. In the present invention, it is more effective to carry out the organic acid fermentation such as alcohol fermentation, lactic acid fermentation, or acetic acid fermentation at the same time as or after the above treatment. If alcohol fermentation is carried out, not only there is no stickiness at the time of application, but also the concentration is easy and the active ingredient can be easily concentrated. If necessary, aeration fermentation with yeast, alcohol precipitation, sugar removal with a synthetic adsorbent and the like may be performed. Further, when the red bran portion of 92% or more was examined, it was found that it was effective but weak.

The product of the present invention obtained as described above is used as it is, or after being squeezed and filtered without separating the residue. When used as is, sterilize or sterilize the product. In addition, when blending the product of the present invention, depending on the actual application, creams, facial cleansers, emulsions, lotions, cleansing, packs, cosmetics such as soaps, ointments, patches, pasta agents, etc. Formulations such as lotions, chicken agents, liment agents, jellies, aerosols and other external medicines. The other compounding ingredients may be any of those usually used, and further, other medicinal agents may be used in combination.

Next, the test results for examining the effect of the product of the present invention as a hot compress are shown below. First, when 0.5 ml of the product of the present invention was directly applied to the backs of the hands of 6 panelists, all of the products of the present invention showed that 4 or more people out of 6 had a warm and compress effect. Also, 2 or more of the 6 panelists said that the blood vessels seemed to have expanded slightly. Therefore, in order to experimentally demonstrate the hot compress effect of the product of the present invention, the skin surface temperature after application of the product of the present invention was examined using a thermography device. 15 panelists were used, and Table 1 shows the average values of the progress of the skin surface temperature of the main test and the control test (water application) read from the thermography.

The method of measuring thermography will be described below. In an examination room at room temperature of 20 ° C ± 1 ° C with no air flow, the subject's forearm is exposed to room temperature for about 30 minutes and then acclimated to room temperature, and then infrared rays radiated from the human body surface are detected. A thermograph of the subject's right forearm and upper back was photographed using a thermographic device that detects temperature information. Next, 5 ml of the product of the present invention was evenly applied to the right forearm elbow of the subject. The shooting interval is 2 minutes, 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes after application of the product of the present invention.
Minutes, 30 minutes, 40 minutes, and changes in skin surface temperature with time were observed. As a control test, water was applied instead of the product of the present invention, and then a thermograph was similarly taken. The temperatures during the control test and the main test are shown in Table 1.

[0015]

[Table 1]

As is clear from Table 1, the results obtained by measuring the forearm as the measurement site showed that the products of the present invention obtained in all the examples showed a difference from the case where water was applied after 10 minutes. A clear difference was observed after 20 minutes from the beginning. Also, in the individual time series data of the panelists,
Some people showed the effect immediately after 2 minutes, and some people showed the difference after 10 minutes, but after 40 minutes, the surface temperature before treatment was the same as in the case of water application, while the product of the present invention was used. In the case of coating, the surface temperature was 0.5 to 2.2 ° C. higher than that before the treatment. As a result, it was found that the product of the present invention has an excellent warm compress effect of raising the temperature of the epidermis.

Further, the product of the present invention obtained in Example 30 was applied to the ear of a mouse, and the vasodilatory action by the addition of the product of the present invention was objectively observed. The test method is DDY mouse 10
The product of the present invention was applied to the ears of the animal three times a day for two weeks. The application amount of one time was such that the product of the present invention was applied twice to a swab on one ear. Further, as a control experiment, physiological saline was used instead of the product of the present invention. The judgment was made by a specialist doctor. As a result, in the case where physiological saline was used as a control, no difference was visually observed before and after application, whereas in the case where the product of the present invention was applied, the effect was obtained about 5 minutes after application in the case of early application. Was observed, and a clear effect was observed until 60 minutes after application. Further, it was found that when the product of the present invention was applied for 2 weeks continuously, the vasodilatory action by the application of the product of the present invention continued for a long time. Similar effects were observed in the products of the present invention obtained in other examples. From these results, it was revealed that the product of the present invention has an extremely excellent effect of improving blood circulation such as a vasodilatory effect, and further has a hot compress effect by improving blood circulation.

[0018]

【Example】

(Example 1) 1 kg of rice without germ was soaked in water at 25 ° C for 3 days to germinate rice. After thoroughly washing the germinated rice, it is dried at 50 ° C. for 24 hours, and then,
The product was finely pulverized to obtain 990 g of the product of the present invention. (Example 2) Brown rice was crushed to obtain a crushed brown rice product 500
g was obtained. 1500 ml of water was added to this pulverized product, PH was dropped with hydrochloric acid, and the mixture was left for 10 days. Then, it was squeezed with a squeezing machine to neutralize the resulting clear liquid to obtain 1200 ml of the product of the present invention and 760 g of a residue. (Example 3) Using 500 g of the product of the present invention obtained in Example 1, the same operation as in Example 3 was carried out to obtain another product of the present invention 11
90 ml was obtained.

Example 4 Brown rice was crushed to obtain 500 g of crushed brown rice. Liquefaction enzyme 10g and water 1500ml were added to this ground product. Then, the temperature was gradually raised, and the mixture was boiled and extracted for 5 minutes and then cooled. Then, it was squeezed with a squeezing machine to obtain 1420 ml of the product of the present invention and 560 g of a residue. (Example 5) Using 500 g of the product of the present invention obtained in Example 1, the same operation as in Example 4 was carried out to obtain another product of the present invention 14
00 ml was obtained. (Example 6) Brown rice is crushed by a crusher to obtain crushed brown rice 500
g was obtained. 1500 ml of 2N-NaOH was added to this pulverized product and the mixture was left for 5 days. Then, it was squeezed with a squeezing machine to obtain 1350 ml of the clear liquid and 650 g of the residue. 1 of this clarified liquid
Neutralization with 0N-HCl gave 1480 ml of the product of the present invention.

(Example 7) Using 500 g of the product of the present invention obtained in Example 1, the same operation as in Example 6 was carried out to obtain another 1490 ml of the product of the present invention. (Embodiment 8) Brown rice is crushed to obtain a crushed brown rice product 500
g was obtained. 1500 ml of 95% ethanol is added to this pulverized product.
Was added and left for 5 days. After that, squeeze with a wringer,
1300 ml of clear liquid and 650 g of residue were obtained. 2000 ml of water was added to this clarified solution, and the mixture was concentrated by a rotary evaporator to obtain 1500 ml of the product of the present invention. (Example 9) Using 500 g of the present invention product obtained in Example 1, the same operation as in Example 8 was carried out to obtain another invention product 15
00 ml was obtained.

Example 10 Brown rice was crushed to obtain 500 g of crushed brown rice. 300 g of koji and 1500 ml of water were added to this pulverized product, and the mixture was left at 55 ° C. for 20 hours. Then, squeezing with a squeezing machine, 1230 ml of the present invention product and 100 residues
0 g was obtained. (Example 11) Using 500 g of the present invention product obtained in Example 1, the same operation as in Example 10 was carried out to obtain another 1210 ml of the present invention product. (Example 12) Brown rice is crushed to obtain a crushed brown rice product 50
0 g was obtained. 2 g of protease and 150 water
0 ml was added and the mixture was left at 50 ° C. for 20 hours. Then, the product was squeezed with a squeezing machine to obtain 1310 ml of the product of the present invention and 670 g of a residue.

(Example 13) Using 500 g of the product of the present invention obtained in Example 1, the same operation as in Example 12 was carried out,
Another 1380 ml of the product of the present invention was obtained. (Example 14) Brown rice is crushed to obtain 50 crushed brown rice.
0 g was obtained. 2 g of lipolytic enzyme and 150 water
0 ml was added and the mixture was left at 50 ° C. for 20 hours. Then, it was squeezed with a squeezing machine to obtain 1290 ml of the product of the present invention and 680 g of a residue. (Example 15) The same operation as in Example 14 was carried out using 500 g of the product of the present invention obtained in Example 1 to obtain 1360 ml of another product of the present invention.

(Example 16) Brown rice was crushed by a crusher to obtain 500 g of crushed brown rice. Fiber-degrading enzyme 2 in this crushed product
g and 1500 ml of water were added, and the mixture was left at 50 ° C. for 20 hours. Then, the product was squeezed with a squeezing machine to obtain 1330 ml of the product of the present invention and 650 g of a residue. (Example 17) The same operation as in Example 16 was carried out using 500 g of the product of the present invention obtained in Example 1 to obtain 1370 ml of another product of the present invention. (Example 18) Brown rice was crushed to obtain a crushed brown rice product 50
0 g was obtained. 2g starch degrading enzyme and 150g water
0 ml was added and the mixture was left at 55 ° C. for 20 hours. Then, it was squeezed with a squeezing machine to obtain 1380 ml of the product of the present invention and 600 g of a residue.

(Example 19) The same operation as in Example 18 was carried out using 500 g of the product of the present invention obtained in Example 1,
Another 1400 ml of the product of the present invention was obtained. (Example 20) Brown rice is crushed to obtain a crushed brown rice product 50
0 g was obtained. Add 2 g of pectin-degrading enzyme and 1 part of water to this ground product.
500 ml was added and left at 50 ° C. for 20 hours. After that, squeezing with a squeezing machine, 1320 ml of the present invention product and residue 660
g was obtained. (Example 21) Using 500 g of the present invention product obtained in Example 1, the same operation as in Example 20 was carried out to obtain another 1300 ml of the present invention product.

(Example 22) Brown rice was crushed to obtain 500 g of crushed brown rice. Proteolytic enzyme 2 in this crushed product
g, lipolytic enzyme 2 g, fiber degrading enzyme 2 g, starch degrading enzyme 2 g, pectin degrading enzyme 2 g and 1500 ml of water were added, and the mixture was allowed to stand at 50 ° C. for 20 hours. Then, it was squeezed with a squeezing machine to obtain 1420 ml of the product of the present invention and 560 g of a residue. (Example 23) Using 500 g of the product of the present invention obtained in Example 1, the same operation as in Example 22 was carried out to obtain another 1440 ml of the product of the present invention. (Example 24) The same operation as in Example 22 was carried out to obtain 2000 g of an enzymatic decomposition product of rice. Then, the temperature was gradually raised, and the mixture was boiled and extracted for 5 minutes and then cooled. Then, it was squeezed with a squeezing machine to obtain 1400 ml of the product of the present invention and 550 g of a residue.

Example 25 Using 500 g of the product of the present invention obtained in Example 1, the same operation as in Example 24 was carried out,
1420 ml of another product of the present invention was obtained. (Example 26) Brown rice was crushed to obtain a crushed brown rice product 50
0 g was obtained. To this crushed product, 300 g of koji and 1500 ml of 40% ethanol were added, and the mixture was left at 55 ° C. for 48 hours. After that, squeeze with a squeezing machine and clarified liquid 1300 ml and residue 850
g was obtained. Then, 1000 ml of water was added to the clarified liquid, and the mixture was concentrated by a rotary evaporator to obtain the product 13 of the present invention.
00 ml was obtained. (Example 27) The same operation as in Example 26 was carried out using 500 g of the present invention product obtained in Example 1 to obtain another 1300 ml of the present invention product.

(Example 28) In the same manner as in Example 4, 2000 g of a rice extract was obtained. To this extract, 2 g of proteolytic enzyme, 2 g of lipolytic enzyme, 2 g of fiber degrading enzyme, 2 g of starch degrading enzyme, 2 g of pectin degrading enzyme were added, and the mixture was heated at 50 ° C for 2
It was left for 4 hours. After that, the product of the present invention 14
00 ml and 580 g of residue were obtained. (Example 29) The same operation as in Example 28 was carried out using 500 g of the present invention product obtained in Example 1 to obtain another 1390 ml of the present invention product. (Example 30) In the same manner as in Example 24, 2000 g of an enzyme-decomposed extract of rice was obtained. Yeast was added to this enzyme-decomposed extract, and alcoholic fermentation was carried out for 16 days. Then, it was squeezed with a squeezing machine to obtain 1880 ml of the product of the present invention and 80 g of a residue.

(Example 31) The same operation as in Example 30 was carried out using 500 g of the product of the present invention obtained in Example 1,
Another 1800 ml of the product of the present invention was obtained. (Example 32) In the same manner as in Example 24, 2000 g of an enzyme-decomposed extract of rice was obtained. The enzyme-decomposed extract was sterilized by boiling, cooled to 37 ° C., 200 ml of a starter in which lactic acid bacteria had been cultured in advance was added, and the mixture was well stirred and sealed, and
Lactic acid fermentation was performed at 7 ° C for 2 days. Then, it was squeezed with a squeezing machine to obtain 1380 ml of the product of the present invention and 500 g of a residue. (Example 33) Using 500 g of the present invention product obtained in Example 1, the same operation as in Example 32 was carried out to obtain another 1400 ml of the present invention product.

(Example 34) To 1000 ml of the product of the present invention obtained in Example 24, 80 ml of 95% ethanol was added, and acetic acid fermentation was carried out for 20 days. Then, filtration was performed to obtain 990 ml of the product of the present invention. (Example 35) Using 500 g of the present invention product obtained in Example 1, the same operation as in Example 34 was carried out to obtain another 1000 ml of the present invention product. The products of the present invention obtained in the above examples,
Examples of the case where the product of the present invention is blended into a lotion and a milky lotion, which may be appropriately used depending on the application, will be described below. The formulation examples are not limited to the examples below.

(Example 36) Toner lotion Product of the present invention obtained in Example 22 10.0% by weight Sorbitol 3.0% by weight Glycerin 5.0% by weight Purified water 76.4% by weight Allantoin 0.1% by weight Polyoxyethylene castor oil derivative 0.5% by weight Ethanol 5% by weight The above ingredients were mixed and dissolved by a conventional method to obtain a lotion.

(Example 37) Emulsion The product of the present invention obtained in Example 2 20.0% by weight Stearic acid 1.3% by weight Cetanol 0.7% by weight Beeswax 2.0% by weight Polyoxyethylene (11) Mono Oleic acid ester 1.2% by weight Glycerin monostearate ester 0.8% by weight Quinceseed extract (5% aqueous solution) 15.0% by weight dipropylene glycol 5.0% by weight Ethanol 3.0% by weight Methylparaben 0.3 % By weight Perfume 0.3% by weight Purified water 50.4% by weight Dipropylene glycol is added to the purified water and heated and stirred,
The temperature is kept at 70 ° C., the product of the present invention, quince seed extract, fragrance and raw materials other than ethanol are added and stirred, and then uniformly emulsified by a homogenizer. While cooling the obtained emulsion, the rest of the emulsion was gradually added to the emulsion and cooled to room temperature to obtain an emulsion.

[0032]

As is apparent from the above results, it is easy to extract rice by water extraction or organic solvent extraction,
Moreover, a very excellent warm poultice having a totally safe effect of improving blood circulation such as a temperature increasing effect and a vasodilatory effect was obtained. Since rice has been the staple food until now, new production methods and uses have hardly been developed.
Furthermore, rice has been the staple food until now, and its safety has been proven. That is, the present invention is
The present inventors have found that not only it has a very excellent effect as a warm poultice, but also its safety is sufficiently demonstrated. In addition, it is extremely significant that the current use of rice is said to be over-produced and that new uses of rice are found and that consumption of rice can be increased by improving the image of rice.

Claims (5)

[Claims] 1. A hot poultice which is a crushed product of germinated rice as it is or contains it. 2. A hot poultice containing the extract of rice or germinated rice as it is or containing it. 3. A hot poultice, which is obtained by enzymatically decomposing or hydrolyzing rice or a hydrolyzed product of germinated rice, or containing the same. 4. A hot poultice, which is obtained by extracting rice or sprouted rice with enzymatic decomposition or koji before or after the extraction, simultaneously with or after the extraction, or containing the same. 5. A hot poultice which comprises the extract of rice or germinated rice or the product of enzymatic decomposition or koji which has been subjected to alcohol fermentation or organic acid fermentation as it is or containing the product.