JPH08208413A - Aerosolagent for controlling interior mite - Google Patents

Abstract

PURPOSE: To obtain an aerosol agent for controlling interior mites, which is effective for carpet treatment. CONSTITUTION: This mite-controlling aerosol agent contains, as active ingredients, permethrin, or a combination thereof with at least one compound selected from octachloro-dipropyl ether, N-(2-ethylhexyl)-1-isopropyl-4- methylbicyclo [2.2.2]-oct-5-ene-2,3-dicarboxyimide, N-(2-ethylhexyl)- bicyclo[2,2,1]hepta-5-ene-2,3-dicarboxyimide, piperonyl butoxide, isobornyl thiocyanoacetate, 2-butoxy-2'-thiocyanoethyl ether, N,N-diethyl-m-toluamide and benzyl benzoate.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an aerosol agent for controlling indoor mites for carpet treatment, which comprises permethrin, or permethrin and one or two synergists for pyrethroids and pest repellents.

[0002]

2. Description of the Related Art A great variety of mites live on the earth, and, for example, citrus red mite and spider mites parasitic on plants cause great damage to agricultural products. These acaricides for agricultural use have been developed for a long time, and recently new promising compounds have been discovered one after another.

[0003]

On the other hand, in recent years, due to changes in the living environment, house dust mites, dust mites, dust mites, etc. occur in the home, which not only causes discomfort, but also causes allergic asthma and skin rash. Is occurring. It was known that organophosphorus agents such as Sumithion and diazinon are effective against mites generated in these indoors, but there are obstacles to their practical use due to safety and resistance problems for humans and animals, and proper disinfection. The establishment of a method has been earnestly desired.

[0004]

[Means for Solving the Problems] In view of the above situation, the inventors of the present invention have conducted extensive studies for the purpose of developing an acaricide that can be safely used indoors, and as a result, phenothrin, permethrin, resmethrin and 3'-fu Enoxybenzyl 2,
One or two compounds of 2,3,3-tetraethylcyclopropanecarboxylate, or isobornyl thiocyanoacetate (hereinafter referred to as IBTA), octachlorodipropyl ether (hereinafter referred to as S-421), piperonylbutane Toxide, N-2 (-ethylhexyl) -bicyclo
[2,2,1] hepta-5-ene-2,3-dicarboximide (hereinafter referred to as cinepyrine 222), N- (2-ethylhexyl) -1-isopropyl-4-methylbicyclo [2,2,2 ] A synergist for pyrethroids such as oct-5-ene-2,3-dicarboximide (hereinafter referred to as cinepyrine 500), 2-butoxy-2′-thiocyanodiethyl ether (hereinafter referred to as Resen 384), and A composition containing one or two pest repellents such as N, N-diethyl-m-toluamide (hereinafter referred to as diet) and benzylbenzoate is extremely effective against mites, dust mites, dust mites, etc. The present invention has been completed by finding that

The present invention comprises permethrin as an active ingredient, or permethrin and octachlorodipropyl ether, N- (2-ethylhexyl) -1-isopropyl-4-methylbicyclo [2,2,2] oct-5.
-Ene-2,3-dicarboximide, N- (2-ethylhexyl) -bicyclo [2,2,1] hept-5-ene-2,3-dicarboximide, piperonyl butoxide, isobornyl thiocyanoacetate , 2-butoxy-2 '
-Thiocyanoethyl ether, N, N-diethyl-m-
The present invention provides an aerosol agent for controlling indoor mites for carpet treatment, which comprises one or two compounds selected from the group consisting of toluamide and benzylbenzoate.

[0006]

DETAILED DESCRIPTION OF THE INVENTION By the way, phenothrin, permethrin, resmethrin and 3'-phenoxybenzyl.
Pyrethroid of 2,2,3,3-tetramethylcyclopropanecarboxylate (hereinafter referred to as compound A) has high insecticidal activity and broad insecticidal spectrum, and is widely used as a highly safe insecticide for household and agricultural purposes. However, the acaricidal activity against citrus red mite and spider mites is extremely weak, and it has been conventionally difficult to apply it to mites in general. However, the present inventors believe that there are some ecological differences between mites attached to plants such as citrus mites, mitid mites, and mites that occur indoors such as mites, dust mites, and for various compounds, for the latter mites As a result of examining the effect, it was found that the above-mentioned four types of pyrethroids (phenothrin, permethrin, resmethrin and compound A) have a particularly high acaricidal effect on mites growing indoors, and especially for mites, sumithione and diazinon. It has been discovered that some of the new pyrethroids, which have recently been shown to be superior in spidericidal activity, are not always effective against mites growing indoors. Furthermore, phenothrin, permethrin and compound A
Compounds with a cyano group introduced at the benzyl position of the alcohol part are generally superior to the original compounds in insecticidal activity and acaricidal activity, but on the contrary, they are more active against mites growing indoors. It became clear that it showed a decrease. These findings are completely unexpected from conventional knowledge, and considering that the pyrethroid of the present invention is widely used as a safe insecticide for humans and animals, it can be killed indoors. It is extremely useful for the development of tick agents.

[0007] In particular, it is thought that Dermatophagoides farinae which occurs in carpets is a cause of allergic diseases and sickness in the human body, and the finding that pyrethroid compounds are effective for these is significant in health and medical terms. It should be noted that 2 in the acid part of phenothrin, permethrin and resmethrin.
There are four asymmetric carbons and four optical isomers are possible, but each or any mixture thereof is of course included in the present invention.

IBTA, S-421, piperonyl butoxide, cinepyrine 222, cinepyrine 50
0, a synergist for pyrethroids such as Reisen 384 and pest repellents such as diet and benzyl benzoate, to some extent, a miticidal effect was observed, and further, the present invention and one of the four pyrethroids described above. Alternatively, it was confirmed that a composition obtained by adding one or two of the above synergists and pest repellents to the two kinds exhibits an extremely high acaricidal effect which is additive or higher.

There are many unclear points as to why the above-mentioned four kinds of pyrethroids have a high specific exterminating effect on the mites and dust mites that occur indoors. It is considered that the morphological difference that the phytoseiid mites are pre-Amphitates are related in part. Pyrethroid synergists have no insecticidal power themselves,
When used together with pyrethroids, it is known to suppress the metabolic decomposition of pyrethroids in insects and improve their insecticidal activity, but it itself has some or considerable acaricidal activity against mites that occur indoors. , Suggesting a difference in mechanism of action between insects and mites. or,
The high synergistic effect of the mixture of pyrethroid and synergist for pyrethroid has high practical value because the latter is very cheap. Although date and benzyl benzoate are compounds that have been widely put to practical use as repellents for mosquitoes, flies, etc., it is interesting that they showed an acaricidal effect, and the composition of the present invention containing them is repellent of unpleasant pests and mites. It can be used as a multipurpose composition including the extermination of genus.

Although the above-mentioned active ingredients can be applied as they are to the acaricide of the present invention, it is usually preferable to use various carriers (wherein the liquid formulation is used here) according to the purpose of use by using a suitable carrier and other compounding agents. The term, means a liquid preparation having a water-soluble form, an emulsified form, or a suspension form, an emulsion, a wettable powder, an oil formulation,
It is used as a flowable agent, water solvent, etc.) and an aerosol agent. Examples of the liquid carrier include water, alcohols (methyl alcohol, ethyl alcohol, ethylene glycol etc.), ketones (acetone, methyl ethyl ketone, cyclohexanone etc.), ethers (ethyl ether, dioxane, cellosolves etc.), aliphatic Hydrocarbons (gasoline, kerosene, kerosene, etc.), aromatic hydrocarbons (benzene, toluene, xylene, methylnaphthalene, etc.), halogenated hydrocarbons (dichloromethane, trichlorobenzene, etc.), esters, acid amides, Solvents such as nitrites are suitable, and one or a mixture of two or more thereof is used. Examples of solid carriers include clays (kaolin, bentonite, etc.),
Talcs, silicas, alumina powders, activated carbons, vegetable powders and the like are suitable, and one or a mixture of two or more thereof is used. Suitable compounding agents include emulsifiers, dispersants, spreading agents, penetrants, surfactants, stabilizers, etc., and one or a mixture of two or more of these is used.

Alternatively, other acaricides, antioxidants, insecticides, which are not likely to inhibit the activity of the active ingredient of the present invention,
You may mix | blend a bactericide, a fungicide, a flavoring agent, and a coloring agent.

The amount of the active ingredient in the acaricide of the present invention and the amount thereof used are appropriately determined depending on the dosage form, application target, application method, application site and the like. For example, to control mites that live in tatami mats such as mites, 0.1 mg or more per 1 tatami, preferably 1 mg
~ 2g of the pyrethroid compound is used. The tatami mats are infested with pests such as beetles and wasps, and the composition of the present invention can also control these pests at the same time. In addition, 0.5 mg to ² g per 1 m ² is used for extermination of Dermatophagoides farinae which inhabit the carpets.
It is preferred that the pyrethroid compound of is applied.

[0013]

The present invention will be described in more detail with reference to the following examples, but the present invention is not limited to the following examples as long as the gist thereof is not exceeded.

Test Example 1 10 g of the powdered feed treated with the test compound and 10 g of the powdered feed containing about 2500 mosquito mites were mixed to obtain a test powdered feed having a predetermined concentration. 5 g of each of the powdered feeds was placed in a petri dish having a diameter of 6 cm and placed under the conditions of a temperature of 25 ° C. and a humidity of 75%. After 1 week and 2 weeks, the number of living mites in 0.2 g of the feed was examined by the saturated saline floating method, and the reproductive inhibition rate was calculated according to the following formula. The test was repeated 3 times for each concentration.

[0015]

[Equation 1]

The symbols in the test compounds and pyrethroids
(a), (b), (c) and (d) have the following meanings. (a); Acid part dl-cis / trans form (b); Acid part d-cis / trans form (c); Acid part dl-cis form (d); Acid part d-trans form

[0017]

[Table 1]

[0018]

Embedded image

From the above results, the composition of the present invention, namely phenothrin, permethrin, resmethrin and compound A
The composition (test compound examples 1 to 7) containing one or two compounds of the above, or one or two synergists for pyrethroids and pest repellents showed excellent acaricidal effect. . On the other hand, other pyrethroid compounds (control compounds (A), (B),
The activity of (C)) and the synergist for pyrethroid or the pest repellent alone is very low, confirming the usefulness of the composition of the present invention.

Test Example 2 10 g of the powdered feed treated with the test compound and 10 g of the powdered feed containing about 1500 Dermatophagoides farinae were mixed to obtain a test powdered feed having a predetermined concentration. The same test as in Test Example 1 was carried out using 5 g of this powdered feed, and the rate of reproductive inhibition after 1 week and 2 weeks was determined.

The symbols (a) in the sample pyrethroid,
(b), (c) and (d) have the same meanings as in Test Example 1, and the control compound (D) is the following compound.

[0022]

Embedded image

[0023]

[Table 2]

From the above results, the composition of the present invention showed a higher acaricidal effect on the mites of Dermatophagoides farinae than the organic phosphorus agent Sumithion, which has been considered to be conventionally effective. The control compound (D) was introduced as a new pyrethroid with high spider mitericidal activity, but its activity against Dermatophagoides farinae was low, suggesting an ecological difference between mites attached to plants and mites occurring indoors. Was done.

Example 1 d-phenothrin (2.0 g) and IBTA (5.0 g) were dissolved in refined kerosene, filled into an aerosol container and fitted with a valve portion, and then a propellant was filled under pressure through the valve portion to obtain an aerosol. It was In a room of 6 tatami mats, in which the mite mite was propagated, the above-mentioned prepared aerosol was infused internally into about 1/4 tatami mat,
When the population density of mites was examined one week later, it was reduced to 5% or more. Similarly, when the aerosol prepared by using ethanol instead of refined kerosene was treated on the carpet in which the reproduction of Dermatophagoides farinae was observed, the same high exterminating effect was obtained.

Example 2 To 5 parts of permethrin and 5 parts of benzyl benzoate, 15 parts of Solpol SM-100 (registered trademark of Toho Kagaku) and 75 parts of purified water were added to obtain an aqueous emulsion. 5 times this emulsion with water
After diluting to 00 times and treating 100 g per m ^{2 of} the base fabric, about 300 pieces of Dermatophagoides farinae were released on the carpet obtained by drying, and the number of surviving Dermatophagoides faridae was examined 2 days later and it was 5 or less.

Example 3 10 parts of dl-cis-phenothrin, 20 parts of IBTA, 35 parts of diatomaceous earth, 30 parts of clay, 3 parts of lauryl sulfonate,
A wettable powder was obtained by pulverizing and mixing 2 parts of carboxymethyl cellulose. This wettable powder was diluted 1000 times with water and treated on the surface of a carpet at 100 g / m ² . After drying
This carpet was used, but no infestation of Dermatophagoides farinae was observed, and there was no problem such as an offensive odor.

[0028]

INDUSTRIAL APPLICABILITY The present invention provides an aerosol agent excellent in controlling indoor mites.

Claims (1)

[Claims] 1. Permethrin as an active ingredient, or permethrin and octachlorodipropyl ether, N- (2-ethylhexyl) -1-isopropyl-4-methylbicyclo [2,2,2] oct-5-ene -2,3-dicarboximide, N- (2-ethylhexyl) -bicyclo [2,2,1] hept-5-ene-2,
1 or 2 selected from the group consisting of 3-dicarboximide, piperonyl butoxide, isobornyl thiocyanoacetate, 2-butoxy-2′-thiocyanoethyl ether, N, N-diethyl-m-toluamide and benzylbenzoate. An indoor mite control aerosol for carpet treatment, consisting of several compounds.