JPH08504276A - ポリペプチドの特異的結合反応性を改良することを含む方法および分析法 - Google Patents
ポリペプチドの特異的結合反応性を改良することを含む方法および分析法Info
- Publication number
- JPH08504276A JPH08504276A JP6522233A JP52223394A JPH08504276A JP H08504276 A JPH08504276 A JP H08504276A JP 6522233 A JP6522233 A JP 6522233A JP 52223394 A JP52223394 A JP 52223394A JP H08504276 A JPH08504276 A JP H08504276A
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- specific binding
- binding
- sodium
- tgfβ
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
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- FUZZWVXGSFPDMH-UHFFFAOYSA-N n-hexanoic acid Natural products CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
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- RBWSWDPRDBEWCR-RKJRWTFHSA-N sodium;(2r)-2-[(2r)-3,4-dihydroxy-5-oxo-2h-furan-2-yl]-2-hydroxyethanolate Chemical compound [Na+].[O-]C[C@@H](O)[C@H]1OC(=O)C(O)=C1O RBWSWDPRDBEWCR-RKJRWTFHSA-N 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/495—Transforming growth factor [TGF]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3759693A | 1993-03-26 | 1993-03-26 | |
| US08/037,596 | 1993-03-26 | ||
| US21538594A | 1994-03-21 | 1994-03-21 | |
| US08/215,385 | 1994-03-21 | ||
| PCT/US1994/003305 WO1994023297A1 (fr) | 1993-03-26 | 1994-03-25 | Procede et methode de titrage impliquant une reactivite par liaison specifique accrue d'un polypeptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH08504276A true JPH08504276A (ja) | 1996-05-07 |
Family
ID=26714285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6522233A Pending JPH08504276A (ja) | 1993-03-26 | 1994-03-25 | ポリペプチドの特異的結合反応性を改良することを含む方法および分析法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0642665A4 (fr) |
| JP (1) | JPH08504276A (fr) |
| AU (1) | AU6525494A (fr) |
| CA (1) | CA2136757A1 (fr) |
| WO (1) | WO1994023297A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023125474A (ja) * | 2022-02-28 | 2023-09-07 | 住友ベークライト株式会社 | セリンプロテアーゼの検出用または測定用試薬 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110392831B (zh) | 2017-01-27 | 2023-09-05 | 豪夫迈·罗氏有限公司 | 用于在相互作用测定中调节信号强度的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL48804A (en) * | 1975-01-29 | 1979-05-31 | Baxter Travenol Lab | Imminological reagent comprising a mixture of polyethyleneglycol and a nonionic surfactant |
| EP0061541A1 (fr) * | 1981-03-27 | 1982-10-06 | Biospecia Limited | Analyse immunologique et agent biochimique pour cette analyse |
| JPS58187862A (ja) * | 1982-04-27 | 1983-11-02 | Sanyo Chem Ind Ltd | 免疫測定改良剤および改良方法 |
-
1994
- 1994-03-25 CA CA 2136757 patent/CA2136757A1/fr not_active Abandoned
- 1994-03-25 JP JP6522233A patent/JPH08504276A/ja active Pending
- 1994-03-25 WO PCT/US1994/003305 patent/WO1994023297A1/fr not_active Ceased
- 1994-03-25 AU AU65254/94A patent/AU6525494A/en not_active Abandoned
- 1994-03-25 EP EP94912878A patent/EP0642665A4/fr not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023125474A (ja) * | 2022-02-28 | 2023-09-07 | 住友ベークライト株式会社 | セリンプロテアーゼの検出用または測定用試薬 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6525494A (en) | 1994-10-24 |
| EP0642665A4 (fr) | 1997-05-02 |
| EP0642665A1 (fr) | 1995-03-15 |
| CA2136757A1 (fr) | 1994-10-13 |
| WO1994023297A1 (fr) | 1994-10-13 |
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