JPH09176084A - Production of 1,4,5,8-tetrahydroxyanthraquinone - Google Patents
Production of 1,4,5,8-tetrahydroxyanthraquinoneInfo
- Publication number
- JPH09176084A JPH09176084A JP32861596A JP32861596A JPH09176084A JP H09176084 A JPH09176084 A JP H09176084A JP 32861596 A JP32861596 A JP 32861596A JP 32861596 A JP32861596 A JP 32861596A JP H09176084 A JPH09176084 A JP H09176084A
- Authority
- JP
- Japan
- Prior art keywords
- added
- solution
- tetrahydroxyanthraquinone
- minutes
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SOGCSKLTQHBFLP-UHFFFAOYSA-N 1,4,5,8-tetrahydroxyanthraquinone Chemical compound O=C1C2=C(O)C=CC(O)=C2C(=O)C2=C1C(O)=CC=C2O SOGCSKLTQHBFLP-UHFFFAOYSA-N 0.000 title claims abstract description 23
- 238000004519 manufacturing process Methods 0.000 title description 2
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 claims abstract description 16
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 claims abstract description 13
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000007788 liquid Substances 0.000 claims abstract description 8
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 7
- ZCSHNCUQKCANBX-UHFFFAOYSA-N lithium diisopropylamide Chemical compound [Li+].CC(C)[N-]C(C)C ZCSHNCUQKCANBX-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000005051 trimethylchlorosilane Substances 0.000 claims abstract description 6
- 238000006243 chemical reaction Methods 0.000 claims abstract description 3
- KDFZYJAUVGWDSW-UHFFFAOYSA-N (5-silyloxy-1H-pyrrol-2-yl)oxysilane Chemical compound [SiH3]OC=1NC(=CC=1)O[SiH3] KDFZYJAUVGWDSW-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000003960 organic solvent Substances 0.000 claims abstract 2
- 239000002994 raw material Substances 0.000 claims abstract 2
- 239000012429 reaction media Substances 0.000 claims abstract 2
- KZNICNPSHKQLFF-UHFFFAOYSA-N succinimide Chemical compound O=C1CCC(=O)N1 KZNICNPSHKQLFF-UHFFFAOYSA-N 0.000 abstract description 8
- 125000000217 alkyl group Chemical group 0.000 abstract description 4
- 125000003118 aryl group Chemical group 0.000 abstract description 4
- 229960002317 succinimide Drugs 0.000 abstract description 4
- 150000001875 compounds Chemical class 0.000 abstract description 3
- 239000007795 chemical reaction product Substances 0.000 abstract description 2
- 239000003814 drug Substances 0.000 abstract description 2
- 239000000975 dye Substances 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 25
- UAOMVDZJSHZZME-UHFFFAOYSA-N diisopropylamine Chemical compound CC(C)NC(C)C UAOMVDZJSHZZME-UHFFFAOYSA-N 0.000 description 12
- 239000000203 mixture Substances 0.000 description 11
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 10
- MZRVEZGGRBJDDB-UHFFFAOYSA-N N-Butyllithium Chemical compound [Li]CCCC MZRVEZGGRBJDDB-UHFFFAOYSA-N 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 238000003756 stirring Methods 0.000 description 7
- 230000002194 synthesizing effect Effects 0.000 description 6
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 5
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 4
- 238000004440 column chromatography Methods 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 229940043279 diisopropylamine Drugs 0.000 description 4
- 239000005416 organic matter Substances 0.000 description 4
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- STROKFBTTJPGBP-UHFFFAOYSA-N 1,2,3,4-tetrahydroxyanthracene-9,10-dione Chemical compound C1=CC=C2C(=O)C3=C(O)C(O)=C(O)C(O)=C3C(=O)C2=C1 STROKFBTTJPGBP-UHFFFAOYSA-N 0.000 description 2
- GHAZCVNUKKZTLG-UHFFFAOYSA-N N-ethylsuccinimide Chemical compound CCN1C(=O)CCC1=O GHAZCVNUKKZTLG-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 125000004433 nitrogen atom Chemical group N* 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- WKVZMKDXJFCMMD-UVWUDEKDSA-L (5ar,8ar,9r)-5-[[(2r,4ar,6r,7r,8r,8as)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5h-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one;azanide;n,3-bis(2-chloroethyl)-2-ox Chemical compound [NH2-].[NH2-].Cl[Pt+2]Cl.ClCCNP1(=O)OCCCN1CCCl.COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3C(O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@H](C)OC[C@H]4O3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 WKVZMKDXJFCMMD-UVWUDEKDSA-L 0.000 description 1
- DUJPMUKIEFLXRE-UHFFFAOYSA-N 1,4,5,8-tetrachloroanthracene-9,10-dione Chemical compound O=C1C2=C(Cl)C=CC(Cl)=C2C(=O)C2=C1C(Cl)=CC=C2Cl DUJPMUKIEFLXRE-UHFFFAOYSA-N 0.000 description 1
- KYEACNNYFNZCST-UHFFFAOYSA-N 1-methylpyrrolidine-2,5-dione Chemical compound CN1C(=O)CCC1=O KYEACNNYFNZCST-UHFFFAOYSA-N 0.000 description 1
- ZTUKZULGOCFJET-UHFFFAOYSA-N 1-phenylpyrrolidine-2,5-dione Chemical compound O=C1CCC(=O)N1C1=CC=CC=C1 ZTUKZULGOCFJET-UHFFFAOYSA-N 0.000 description 1
- 238000005698 Diels-Alder reaction Methods 0.000 description 1
- NQTADLQHYWFPDB-UHFFFAOYSA-N N-Hydroxysuccinimide Chemical compound ON1C(=O)CCC1=O NQTADLQHYWFPDB-UHFFFAOYSA-N 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、１，４，５，８−
テトラヒドロキシアントラキノンの製造方法に関する。TECHNICAL FIELD The present invention relates to 1, 4, 5, 8-
The present invention relates to a method for producing tetrahydroxyanthraquinone.
【０００２】[0002]
【従来の技術】１，４，５，８−テトラヒドロキシアン
トラキノンは、色素・医薬品の合成中間体として有用な
化合物であり、これまでに知られている合成法の例とし
ては５，８−ジクロロ−１，４−ジヒドロキシアントラ
キノンから合成する方法（欧州特許公報ＥＡ３８，７７
７号公報）や、１，４，５，８−テトラクロロアントラ
キノンから合成する方法等があった。2. Description of the Related Art 1,4,5,8-Tetrahydroxyanthraquinone is a compound useful as a synthetic intermediate for dyes and pharmaceuticals. As an example of the synthetic method known so far, 5,8-dichloro is known. Method of Synthesis from -1,4-Dihydroxyanthraquinone (European Patent Publication EA38,77
No. 7), and a method of synthesizing from 1,4,5,8-tetrachloroanthraquinone.
【０００３】[0003]
【発明が解決しようとする課題】しかしながら、上記の
公知例は、いずれの場合も原料となる化合物が高価、あ
るいは入手困難であるという問題があった。本発明の目
的は、上記１，４，５，８−テトラヒドロキシアントラ
キノンの、効率の良い合成方法を提供することにある。However, in any of the above-mentioned publicly known examples, there is a problem that the starting material compound is expensive or difficult to obtain. An object of the present invention is to provide an efficient method for synthesizing the above 1,4,5,8-tetrahydroxyanthraquinone.
【０００４】[0004]
【課題を解決するための手段】本発明は、検討を重ねた
結果、窒素上にアルキル基、水酸基、またはアリール基
のうちいずれかを持つコハク酸イミドから、窒素上に置
換基を持つ２，５−ジシロキシピロールを調製し、これ
とｐ−ベンゾキノンを反応させることによって１，４，
５，８−テトラヒドロキシアントラキノンを安価かつ容
易に大量合成できることを見いだした。Means for Solving the Problems As a result of extensive studies, the present invention has revealed that a succinimide having either an alkyl group, a hydroxyl group or an aryl group on a nitrogen atom, and a succinimide having a substituent group on the nitrogen atom. 5-disiloxypyrrole was prepared and reacted with p-benzoquinone to give 1,4,4
It has been found that 5,8-tetrahydroxyanthraquinone can be inexpensively and easily synthesized in large quantities.
【０００５】本発明において、１，４，５，８−テトラ
ヒドロキシアントラキノンは下式に従って合成される。In the present invention, 1,4,5,8-tetrahydroxyanthraquinone is synthesized according to the following formula.
【０００６】[0006]
【化１】 Embedded image
【０００７】上記反応式において、窒素上にアルキル
基、水酸基、またはアリール基のうちいずれかを持つコ
ハク酸イミドは、リチウムジイソプロピルアミドによっ
て脱プロトン化され、塩化トリメチルシランを加えるこ
とによって、窒素上に置換基を持つ２，５−ジシロキシ
ピロールへと変換される。この２，５−ジシロキシピロ
ールは、単離することなくｐ−ベンゾキノンとディール
ス・アルダー反応させる。ここで生じた反応生成物を希
塩酸で処理することによって、粗１，４，５，８−テト
ラヒドロキシアントラキノンを得る。In the above reaction scheme, a succinimide having either an alkyl group, a hydroxyl group, or an aryl group on the nitrogen is deprotonated with lithium diisopropylamide and added to the nitrogen by adding trimethylsilane chloride. It is converted to 2,5-disyloxypyrrole having a substituent. This 2,5-disyloxypyrrole is reacted with p-benzoquinone without a Diels-Alder reaction. The reaction product generated here is treated with dilute hydrochloric acid to obtain crude 1,4,5,8-tetrahydroxyanthraquinone.
【０００８】[0008]
【発明の実施の形態】以下に、本発明の１，４，５，８
−テトラヒドロキシアントラキノンの合成例を示す。BEST MODE FOR CARRYING OUT THE INVENTION 1, 4, 5, 8 of the present invention will be described below.
-A synthesis example of tetrahydroxyanthraquinone is shown.
【０００９】（実施例１） １，４，５，８−テトラヒドロキシアントラキノンの合
成方法（１） −７８℃にて、ジイソプロピルアミン３０．８ｍｌ
（０．２２ｍｏｌ）に１．５０規定のｎ−ブチルリチウ
ム１４７．０ｍｌを加え、１０分間攪拌する。この溶液
に、−７８℃を保った状態でＮ−エチルコハク酸イミド
１２．７０ｇ（０．１ｍｏｌ）をテトラヒドロフラン
（ＴＨＦ）２００ｍｌに溶解した溶液を加える。３０分
間の攪拌の後、溶液を０℃として、トリメチルクロロシ
ラン２７．９ｍｌ（０．２２ｍｏｌ）を加えてさらに３
０分間攪拌する。この溶液にｐ−ベンゾキノン４．３２
ｇ（０．０４ｍｏｌ）を加え、液温を５０℃として３０
分間攪拌の後、氷冷しながら希塩酸（３規定）２００ｍ
ｌをこの溶液に加え、３０分間攪拌する。この溶液か
ら、有機物をエーテルで３回抽出し、無水硫酸マグネシ
ウムでエーテル層を乾燥させた後にエーテルを除去し、
残留物をカラムクロマトグラフィー（展開溶媒エーテル
／ヘキサン＝１／２）で精製することにより、１，４，
５，８−テトラヒドロキシアントラキノン３．８０ｇ
（収率３５％）を得た。(Example 1) Method for synthesizing 1,4,5,8-tetrahydroxyanthraquinone (1) 30.8 ml of diisopropylamine at -78 ° C
147.0 ml of 1.50 N-butyllithium was added to (0.22 mol), and the mixture was stirred for 10 minutes. To this solution, a solution prepared by dissolving 12.70 g (0.1 mol) of N-ethylsuccinimide in 200 ml of tetrahydrofuran (THF) is added while maintaining -78 ° C. After stirring for 30 minutes, the temperature of the solution was adjusted to 0 ° C., 27.9 ml (0.22 mol) of trimethylchlorosilane was added, and the mixture was further added to 3 times.
Stir for 0 minutes. P-benzoquinone 4.32 was added to this solution.
g (0.04 mol) was added, and the liquid temperature was adjusted to 50 ° C. to 30
After stirring for 1 minute, dilute hydrochloric acid (3N) 200m while cooling with ice
1 is added to this solution and stirred for 30 minutes. From this solution, the organic matter was extracted with ether three times, the ether layer was dried over anhydrous magnesium sulfate, and then the ether was removed.
By refining the residue by column chromatography (developing solvent ether / hexane = 1/2), 1,4,
5,8-Tetrahydroxyanthraquinone 3.80 g
(35% yield).
【００１０】（実施例２） １，４，５，８−テトラヒドロキシアントラキノンの合
成方法（２） −７８℃にて、ジイソプロピルアミン３０．８ｍｌ
（０．２２ｍｏｌ）に１．５０規定のｎ−ブチルリチウ
ム１４７．０ｍｌを加え、１０分間攪拌する。この溶液
に、−７８℃を保った状態でＮ−メチルコハク酸イミド
１１．３１ｇ（０．１ｍｏｌ）をテトラヒドロフラン２
００ｍｌに溶解した溶液を加える。３０分間の攪拌の
後、溶液を０℃として、トリメチルクロロシラン２７．
９ｍｌ（０．２２ｍｏｌ）を加えてさらに３０分間攪拌
する。この溶液にｐ−ベンゾキノン４．３２ｇ（０．０
４ｍｏｌ）を加え、液温を５０℃として３０分間攪拌の
後、氷冷しながら希塩酸（３規定）２００ｍｌをこの溶
液に加え、３０分間攪拌する。この溶液から、有機物を
エーテルで３回抽出し、無水硫酸マグネシウムでエーテ
ル層を乾燥させた後にエーテルを除去し、残留物をカラ
ムクロマトグラフィーで精製することにより、１，４，
５，８−テトラヒドロキシアントラキノン４．１３ｇ
（収率３８％）を得た。(Example 2) Method for synthesizing 1,4,5,8-tetrahydroxyanthraquinone (2) Diisopropylamine 30.8 ml at -78 ° C
147.0 ml of 1.50 N-butyllithium was added to (0.22 mol), and the mixture was stirred for 10 minutes. To this solution, 11.31 g (0.1 mol) of N-methylsuccinimide was added in tetrahydrofuran 2 while maintaining -78 ° C.
Add the solution dissolved in 00 ml. After stirring for 30 minutes, the solution was brought to 0 ° C. and trimethylchlorosilane 27.
9 ml (0.22 mol) is added and the mixture is stirred for another 30 minutes. 4.32 g (0.0%) of p-benzoquinone was added to this solution.
(4 mol), the liquid temperature is set to 50 ° C., and the mixture is stirred for 30 minutes, then 200 ml of dilute hydrochloric acid (3N) is added to this solution while cooling with ice, and the mixture is stirred for 30 minutes. From this solution, the organic matter was extracted three times with ether, the ether layer was dried over anhydrous magnesium sulfate, the ether was removed, and the residue was purified by column chromatography to give 1,4,4.
4.13 g of 5,8-tetrahydroxyanthraquinone
(38% yield).
【００１１】（実施例３） １，４，５，８−テトラヒドロキシアントラキノンの合
成方法（３） −７８℃にて、ジイソプロピルアミン３０．８ｍｌ
（０．２２ｍｏｌ）に１．５０規定のｎ−ブチルリチウ
ム１４７．０ｍｌを加え、１０分間攪拌する。この溶液
に、−７８℃を保った状態でＮ−フェニルコハク酸イミ
ド１７．５２ｇ（０．１ｍｏｌ）をテトラヒドロフラン
２００ｍｌに溶解した溶液を加える。３０分間の攪拌の
後、溶液を０℃として、トリメチルクロロシラン２７．
９ｍｌ（０．２２ｍｏｌ）を加えてさらに３０分間攪拌
する。この溶液にｐ−ベンゾキノン４．３２ｇ（０．０
４ｍｏｌ）を加え、液温を５０℃として３０分間攪拌の
後、氷冷しながら希塩酸（３規定）２００ｍｌをこの溶
液に加え、３０分間攪拌する。この溶液から、有機物を
エーテルで３回抽出し、無水硫酸マグネシウムでエーテ
ル層を乾燥させた後にエーテルを除去し、残留物をカラ
ムクロマトグラフィーで精製することにより、１，４，
５，８−テトラヒドロキシアントラキノン４．１３ｇ
（収率３１％）を得た。(Example 3) Method for synthesizing 1,4,5,8-tetrahydroxyanthraquinone (3) 30.8 ml of diisopropylamine at -78 ° C
147.0 ml of 1.50 N-butyllithium was added to (0.22 mol), and the mixture was stirred for 10 minutes. To this solution, a solution prepared by dissolving 17.52 g (0.1 mol) of N-phenylsuccinimide in 200 ml of tetrahydrofuran is added while maintaining -78 ° C. After stirring for 30 minutes, the solution was brought to 0 ° C. and trimethylchlorosilane 27.
9 ml (0.22 mol) is added and the mixture is stirred for another 30 minutes. 4.32 g (0.0%) of p-benzoquinone was added to this solution.
(4 mol), the liquid temperature is set to 50 ° C., and the mixture is stirred for 30 minutes, then 200 ml of dilute hydrochloric acid (3N) is added to this solution while cooling with ice, and the mixture is stirred for 30 minutes. From this solution, the organic matter was extracted three times with ether, the ether layer was dried over anhydrous magnesium sulfate, the ether was removed, and the residue was purified by column chromatography to give 1,4,4.
4.13 g of 5,8-tetrahydroxyanthraquinone
(Yield 31%) was obtained.
【００１２】（実施例４） １，４，５，８−テトラヒドロキシアントラキノンの合
成方法（４） −７８℃にて、ジイソプロピルアミン４６．２ｍｌ
（０．３３ｍｏｌ）に１．５０規定のｎ−ブチルリチウ
ム２２０．５ｍｌを加え、１０分間攪拌する。この溶液
に、−７８℃を保った状態でＮ−ヒドロキシコハク酸イ
ミド１１．５１ｇ（０．１ｍｏｌ）をテトラヒドロフラ
ン２００ｍｌに溶解した溶液を加える。３０分間の攪拌
の後、溶液を０℃として、トリメチルクロロシラン４
１．９ｍｌ（０．３３ｍｏｌ）を加えてさらに３０分間
攪拌する。この溶液にｐ−ベンゾキノン４．３２ｇ
（０．０４ｍｏｌ）を加え、液温を５０℃として３０分
間攪拌の後、氷冷しながら希塩酸（３規定）２００ｍｌ
をこの溶液に加え、３０分間攪拌する。この溶液から、
有機物をエーテルで３回抽出し、無水硫酸マグネシウム
でエーテル層を乾燥させた後にエーテルを除去し、残留
物をカラムクロマトグラフィーで精製することにより、
１，４，５，８−テトラヒドロキシアントラキノン４．
１３ｇ（収率３６％）を得た。(Example 4) Method for synthesizing 1,4,5,8-tetrahydroxyanthraquinone (4) At -78 ° C, 46.2 ml of diisopropylamine.
To (0.33 mol), 220.5 ml of 1.50 N-butyllithium is added and stirred for 10 minutes. To this solution, a solution prepared by dissolving 11.51 g (0.1 mol) of N-hydroxysuccinimide in 200 ml of tetrahydrofuran is added while maintaining -78 ° C. After stirring for 30 minutes, the solution was brought to 0 ° C. and trimethylchlorosilane 4 was added.
Add 1.9 ml (0.33 mol) and stir for another 30 minutes. 4.32 g of p-benzoquinone was added to this solution.
(0.04 mol) was added, the liquid temperature was adjusted to 50 ° C., the mixture was stirred for 30 minutes, and then 200 ml of dilute hydrochloric acid (3N) was added while cooling with ice.
Is added to this solution and stirred for 30 minutes. From this solution,
The organic matter was extracted three times with ether, the ether layer was dried over anhydrous magnesium sulfate, the ether was removed, and the residue was purified by column chromatography.
1,4,5,8-tetrahydroxyanthraquinone4.
13 g (36% yield) were obtained.
【００１３】[0013]
【発明の効果】本発明によって、１，４，５，８−テト
ラヒドロキシアントラキノンを安価かつ容易に合成可能
となった。According to the present invention, 1,4,5,8-tetrahydroxyanthraquinone can be synthesized inexpensively and easily.
Claims (1)
アリールコハク酸イミドを原料として、−７８℃で、液
体窒素中でも液体の有機溶媒中でリチウムジイソプロピ
ルアミドと反応させ、ついでトリメチルクロロシランを
加え、中間体として得られる２，５−ジシロキシピロー
ルを単離することなく同じ反応媒質中でｐ−ベンゾキノ
ンと５０℃にて反応させ、続いてこの反応溶液に希塩酸
を加えることを特徴とする１，４，５，８−テトラヒド
ロキシアントラキノンの製造方法。1. N-alkyl, N-hydroxy or N-
Using arylsuccinimide as a raw material, at −78 ° C., it is reacted with lithium diisopropylamide in a liquid organic solvent in liquid nitrogen, and then trimethylchlorosilane is added to isolate 2,5-disiloxypyrrole obtained as an intermediate. Without reacting with p-benzoquinone in the same reaction medium at 50 ° C., and then dilute hydrochloric acid is added to the reaction solution to prepare 1,4,5,8-tetrahydroxyanthraquinone.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32861596A JP2687955B2 (en) | 1996-12-09 | 1996-12-09 | Method for producing 1,4,5,8-tetrahydroxyanthraquinone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32861596A JP2687955B2 (en) | 1996-12-09 | 1996-12-09 | Method for producing 1,4,5,8-tetrahydroxyanthraquinone |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP18005694A Division JP2638491B2 (en) | 1994-08-01 | 1994-08-01 | Organic storage molecule, method for producing the same, recording medium using the same, and method for storage / reproduction / erasure thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH09176084A true JPH09176084A (en) | 1997-07-08 |
| JP2687955B2 JP2687955B2 (en) | 1997-12-08 |
Family
ID=18212258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP32861596A Expired - Lifetime JP2687955B2 (en) | 1996-12-09 | 1996-12-09 | Method for producing 1,4,5,8-tetrahydroxyanthraquinone |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2687955B2 (en) |
-
1996
- 1996-12-09 JP JP32861596A patent/JP2687955B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2687955B2 (en) | 1997-12-08 |
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