JPH10507187A - 置換されたスピロアルキルアミノおよびスピロアルコキシ複素環化合物、それらの製法および殺虫剤および殺菌剤としてのそれらの使用 - Google Patents

置換されたスピロアルキルアミノおよびスピロアルコキシ複素環化合物、それらの製法および殺虫剤および殺菌剤としてのそれらの使用

Info

Publication number: JPH10507187A
Authority: JP; Japan
Prior art keywords: group; alkyl; oxygen; formula; ring
Prior art date: 1994-10-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP8512898A

Other languages

English (en)

Japanese (ja)

Inventor

シヤーパー，ヴオルフガング

プロイス，ライナー

ブラウン，ペーター

ケルン，マンフレート

クナウフ，ヴエルナー

ザクセ，ブルクハルト

ザンフト，ウルリヒ

ヴアルタースドルフアー，アナ

ボーニン，ヴエルナー

リンキース，アードルフ

ロイシユリング，デイーター

Original Assignee

ヘキスト・シエーリング・アグレボ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-13

Filing date

1995-10-05

Publication date

1998-07-14

1995-10-05 Application filed by ヘキスト・シエーリング・アグレボ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング filed Critical ヘキスト・シエーリング・アグレボ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング

1998-07-14 Publication of JPH10507187A publication Critical patent/JPH10507187A/ja

Status Pending legal-status Critical Current

Links

239000000417 fungicide Substances 0.000 title claims abstract description 10
239000002917 insecticide Substances 0.000 title claims abstract description 8
238000002360 preparation method Methods 0.000 title description 7
150000002391 heterocyclic compounds Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 claims abstract description 91
229910052760 oxygen Inorganic materials 0.000 claims abstract description 60
229910052736 halogen Inorganic materials 0.000 claims abstract description 43
150000002367 halogens Chemical class 0.000 claims abstract description 43
125000000217 alkyl group Chemical group 0.000 claims abstract description 33
229910052717 sulfur Inorganic materials 0.000 claims abstract description 27
238000000034 method Methods 0.000 claims abstract description 13
125000003545 alkoxy group Chemical group 0.000 claims abstract description 6
-1 cyano, thiocyano Chemical group 0.000 claims description 181
239000000203 mixture Substances 0.000 claims description 83
239000001301 oxygen Substances 0.000 claims description 54
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 50
239000013543 active substance Substances 0.000 claims description 46
239000011737 fluorine Substances 0.000 claims description 42
229910052731 fluorine Inorganic materials 0.000 claims description 42
229910052739 hydrogen Inorganic materials 0.000 claims description 26
239000001257 hydrogen Substances 0.000 claims description 26
125000000623 heterocyclic group Chemical group 0.000 claims description 25
150000003839 salts Chemical class 0.000 claims description 25
239000000460 chlorine Substances 0.000 claims description 23
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 22
229910052801 chlorine Inorganic materials 0.000 claims description 21
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 20
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 20
125000003118 aryl group Chemical group 0.000 claims description 20
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 17
125000004122 cyclic group Chemical group 0.000 claims description 17
239000011593 sulfur Substances 0.000 claims description 17
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 16
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 16
125000003342 alkenyl group Chemical group 0.000 claims description 14
125000000304 alkynyl group Chemical group 0.000 claims description 14
125000004093 cyano group Chemical group *C#N 0.000 claims description 14
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239000002253 acid Substances 0.000 claims description 12
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GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 11
241000244206 Nematoda Species 0.000 claims description 10
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229910052799 carbon Inorganic materials 0.000 claims description 10
238000004519 manufacturing process Methods 0.000 claims description 10
238000006467 substitution reaction Methods 0.000 claims description 10
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 9
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 9
HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 claims description 9
125000004429 atom Chemical group 0.000 claims description 9
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 9
125000003107 substituted aryl group Chemical group 0.000 claims description 9
125000004104 aryloxy group Chemical group 0.000 claims description 8
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125000005842 heteroatom Chemical group 0.000 claims description 8
125000004468 heterocyclylthio group Chemical group 0.000 claims description 8
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125000005110 aryl thio group Chemical group 0.000 claims description 7
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229920006395 saturated elastomer Polymers 0.000 claims description 7
125000004434 sulfur atom Chemical group 0.000 claims description 7
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 6
239000000654 additive Substances 0.000 claims description 6
125000004414 alkyl thio group Chemical group 0.000 claims description 6
125000001118 alkylidene group Chemical group 0.000 claims description 6
125000003435 aroyl group Chemical group 0.000 claims description 6
125000005279 aryl sulfonyloxy group Chemical group 0.000 claims description 6
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims description 6
125000005844 heterocyclyloxy group Chemical group 0.000 claims description 6
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229910052757 nitrogen Inorganic materials 0.000 claims description 6
239000003755 preservative agent Substances 0.000 claims description 6
JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 claims description 6
125000001424 substituent group Chemical group 0.000 claims description 6
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125000004453 alkoxycarbonyl group Chemical group 0.000 claims description 5
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125000001589 carboacyl group Chemical group 0.000 claims description 5
125000001188 haloalkyl group Chemical group 0.000 claims description 5
125000004776 1-fluoroethyl group Chemical group [H]C([H])([H])C([H])(F)* 0.000 claims description 4
MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims description 4
241000237852 Mollusca Species 0.000 claims description 4
125000005161 aryl oxy carbonyl group Chemical group 0.000 claims description 4
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125000004423 acyloxy group Chemical group 0.000 claims description 3
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230000000844 anti-bacterial effect Effects 0.000 claims description 3
239000005068 cooling lubricant Substances 0.000 claims description 3
239000010730 cutting oil Substances 0.000 claims description 3
125000000000 cycloalkoxy group Chemical group 0.000 claims description 3
150000002009 diols Chemical class 0.000 claims description 3
238000005553 drilling Methods 0.000 claims description 3
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 claims description 3
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238000005555 metalworking Methods 0.000 claims description 3
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150000003254 radicals Chemical class 0.000 claims description 3
125000005031 thiocyano group Chemical group S(C#N)* 0.000 claims description 3
229910052720 vanadium Inorganic materials 0.000 claims description 3
125000005278 alkyl sulfonyloxy group Chemical group 0.000 claims description 2
239000005667 attractant Substances 0.000 claims description 2
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238000009795 derivation Methods 0.000 claims description 2
239000003814 drug Substances 0.000 claims description 2
125000001153 fluoro group Chemical group F* 0.000 claims description 2
239000004009 herbicide Substances 0.000 claims description 2
230000001069 nematicidal effect Effects 0.000 claims description 2
239000005645 nematicide Substances 0.000 claims description 2
125000005740 oxycarbonyl group Chemical group [*:1]OC([*:2])=O 0.000 claims description 2
125000004430 oxygen atom Chemical group O* 0.000 claims description 2
125000005493 quinolyl group Chemical group 0.000 claims description 2
238000007363 ring formation reaction Methods 0.000 claims description 2
230000000855 fungicidal effect Effects 0.000 claims 3
239000003377 acid catalyst Substances 0.000 claims 2
125000001183 hydrocarbyl group Chemical group 0.000 claims 2
238000007789 sealing Methods 0.000 claims 2
239000000758 substrate Substances 0.000 claims 2
SMSHIXOEBWOYJS-UHFFFAOYSA-N 5,6,7,8-tetrahydroquinazoline Chemical compound C1=NC=C2CCCCC2=N1 SMSHIXOEBWOYJS-UHFFFAOYSA-N 0.000 claims 1
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239000002671 adjuvant Substances 0.000 claims 1
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244000078703 ectoparasite Species 0.000 claims 1
244000000004 fungal plant pathogen Species 0.000 claims 1
125000000262 haloalkenyl group Chemical group 0.000 claims 1
MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 claims 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 1
125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
125000004527 pyrimidin-4-yl group Chemical group N1=CN=C(C=C1)* 0.000 abstract 1
YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 34
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YWSCPYYRJXKUDB-KAKFPZCNSA-N tralomethrin Chemical compound CC1(C)[C@@H](C(Br)C(Br)(Br)Br)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 YWSCPYYRJXKUDB-KAKFPZCNSA-N 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
230000009466 transformation Effects 0.000 description 1
238000000844 transformation Methods 0.000 description 1
BAZVSMNPJJMILC-UHFFFAOYSA-N triadimenol Chemical compound C1=NC=NN1C(C(O)C(C)(C)C)OC1=CC=C(Cl)C=C1 BAZVSMNPJJMILC-UHFFFAOYSA-N 0.000 description 1
125000004665 trialkylsilyl group Chemical group 0.000 description 1
AMFGTOFWMRQMEM-UHFFFAOYSA-N triazophos Chemical compound N1=C(OP(=S)(OCC)OCC)N=CN1C1=CC=CC=C1 AMFGTOFWMRQMEM-UHFFFAOYSA-N 0.000 description 1
NFACJZMKEDPNKN-UHFFFAOYSA-N trichlorfon Chemical compound COP(=O)(OC)C(O)C(Cl)(Cl)Cl NFACJZMKEDPNKN-UHFFFAOYSA-N 0.000 description 1
DQJCHOQLCLEDLL-UHFFFAOYSA-N tricyclazole Chemical compound CC1=CC=CC2=C1N1C=NN=C1S2 DQJCHOQLCLEDLL-UHFFFAOYSA-N 0.000 description 1
229940086542 triethylamine Drugs 0.000 description 1
HSMVPDGQOIQYSR-KGENOOAVSA-N triflumizole Chemical compound C1=CN=CN1C(/COCCC)=N/C1=CC=C(Cl)C=C1C(F)(F)F HSMVPDGQOIQYSR-KGENOOAVSA-N 0.000 description 1
125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 description 1
125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 1
FIQMHBFVRAXMOP-UHFFFAOYSA-N triphenylphosphane oxide Chemical compound C=1C=CC=CC=1P(C=1C=CC=CC=1)(=O)C1=CC=CC=C1 FIQMHBFVRAXMOP-UHFFFAOYSA-N 0.000 description 1
OOLLAFOLCSJHRE-ZHAKMVSLSA-N ulipristal acetate Chemical compound C1=CC(N(C)C)=CC=C1[C@@H]1C2=C3CCC(=O)C=C3CC[C@H]2[C@H](CC[C@]2(OC(C)=O)C(C)=O)[C@]2(C)C1 OOLLAFOLCSJHRE-ZHAKMVSLSA-N 0.000 description 1
125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
JARYYMUOCXVXNK-IMTORBKUSA-N validamycin Chemical compound N([C@H]1C[C@@H]([C@H]([C@H](O)[C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)CO)[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O JARYYMUOCXVXNK-IMTORBKUSA-N 0.000 description 1
239000000052 vinegar Substances 0.000 description 1
235000021419 vinegar Nutrition 0.000 description 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1
239000001993 wax Substances 0.000 description 1
238000005303 weighing Methods 0.000 description 1
239000011592 zinc chloride Substances 0.000 description 1
235000005074 zinc chloride Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
- C09D5/14—Paints containing biocides, e.g. fungicides, insecticides or pesticides
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K3/00—Materials not provided for elsewhere
- C09K3/10—Materials in mouldable or extrudable form for sealing or packing joints or covers
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2200/00—Chemical nature of materials in mouldable or extrudable form for sealing or packing joints or covers
- C09K2200/04—Non-macromolecular organic compounds
- C09K2200/0458—Nitrogen-containing compounds
- C09K2200/0476—Heterocyclic nitrogen compounds, e.g. melamine

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Plant Pathology (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Materials Engineering (AREA)
Agronomy & Crop Science (AREA)
Pest Control & Pesticides (AREA)
Dentistry (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Quinoline Compounds (AREA)
Pyridine Compounds (AREA)

JP8512898A 1994-10-13 1995-10-05 置換されたスピロアルキルアミノおよびスピロアルコキシ複素環化合物、それらの製法および殺虫剤および殺菌剤としてのそれらの使用 Pending JPH10507187A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE4436509A DE4436509A1 (de)	1994-10-13	1994-10-13	Substituierte Spiroalkylamino- und alkoxy-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide
DE4436509.8		1994-10-13
PCT/EP1995/003927 WO1996011924A1 (de)	1994-10-13	1995-10-05	Substituierte spiroalkylamino- und -alkoxy-heterocyclen, verfahren zu ihrer herstellung und ihre verwendung als schädlingsbekämpfungsmittel und fungizide

Publications (1)

Publication Number	Publication Date
JPH10507187A true JPH10507187A (ja)	1998-07-14

Family

ID=6530616

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP8512898A Pending JPH10507187A (ja)	1994-10-13	1995-10-05	置換されたスピロアルキルアミノおよびスピロアルコキシ複素環化合物、それらの製法および殺虫剤および殺菌剤としてのそれらの使用

Country Status (14)

Country	Link
US (1)	US5859009A (de)
EP (1)	EP0785934A1 (de)
JP (1)	JPH10507187A (de)
KR (1)	KR970706278A (de)
AU (1)	AU3803995A (de)
BR (1)	BR9509308A (de)
CA (1)	CA2202459A1 (de)
DE (1)	DE4436509A1 (de)
HU (1)	HUT77203A (de)
IL (1)	IL115571A0 (de)
MX (1)	MX9702690A (de)
TR (1)	TR199501240A2 (de)
WO (1)	WO1996011924A1 (de)
ZA (1)	ZA958594B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9810860D0 (en) *	1998-05-20	1998-07-22	Hoechst Schering Agrevo Gmbh	Substituted pyridine and pyrimidines, processes for their preparation and their use as pesticides
PT1154774E (pt)	1999-02-10	2005-10-31	Astrazeneca Ab	Derivados de quinazolina como inibidores de angiogenese
UA72611C2 (uk) *	2000-05-17	2005-03-15	Орто-Макнейл Фармацевтикал, Інк.	Похідні заміщеного піролопіридинону, корисні як інгібітори фосфодіестерази
UA74826C2 (en)	2000-05-17	2006-02-15	Ortho Mcneil Pharm Inc	?-carboline derivatives as phosphodiesterase inhibitors
ES2289159T3 (es)	2001-11-14	2008-02-01	Ortho-Mcneil Pharmaceutical Corporation	Derivados tetraciclicos sustituidos de pirroloquinolona utilizados como inhibidores de fosfodiesterasa.
EP1622569B1 (de)	2003-04-24	2015-12-02	Incyte Corporation	Aza-spiro-alkan-derivate als hemmer von metallproteasen
GB0330002D0 (en) *	2003-12-24	2004-01-28	Astrazeneca Ab	Quinazoline derivatives
EP2258358A3 (de)	2005-08-26	2011-09-07	Braincells, Inc.	Neurogenese mit Acetylcholinesterasehemmer
EP2275095A3 (de)	2005-08-26	2011-08-17	Braincells, Inc.	Neurogenese durch modulation des Muscarinrezeptors
EP1940389A2 (de)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation von neurogenese durch pde-hemmung
AU2006308889A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en) *	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US20070244143A1 (en) *	2006-03-08	2007-10-18	Braincells, Inc	Modulation of neurogenesis by nootropic agents
JP2009536667A (ja) *	2006-05-09	2009-10-15	ブレインセルス，インコーポレイティド	５ｈｔ受容体介在性の神経新生
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
EP2382975A3 (de)	2006-05-09	2012-02-29	Braincells, Inc.	Neurogenese mittels Angiotensin-Modulation
AU2007292848A1 (en) *	2006-09-08	2008-03-13	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
AU2007299920A1 (en) *	2006-09-19	2008-03-27	Braincells, Inc.	PPAR Mediated Modulation of Neurogenesis
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0519211A1 (de) *	1991-05-17	1992-12-23	Hoechst Schering AgrEvo GmbH	Substituierte 4-Aminopyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
US5399564A (en) *	1991-09-03	1995-03-21	Dowelanco	N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides
DE4208254A1 (de) *	1992-03-14	1993-09-16	Hoechst Ag	Substituierte pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel und fungizid
DE4331179A1 (de) *	1993-09-14	1995-03-16	Hoechst Schering Agrevo Gmbh	Substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide
DE4331181A1 (de) *	1993-09-14	1995-03-16	Hoechst Schering Agrevo Gmbh	Substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide

1994
- 1994-10-13 DE DE4436509A patent/DE4436509A1/de not_active Withdrawn
1995
- 1995-10-05 CA CA002202459A patent/CA2202459A1/en not_active Abandoned
- 1995-10-05 HU HU9701850A patent/HUT77203A/hu unknown
- 1995-10-05 EP EP95935903A patent/EP0785934A1/de not_active Withdrawn
- 1995-10-05 AU AU38039/95A patent/AU3803995A/en not_active Abandoned
- 1995-10-05 JP JP8512898A patent/JPH10507187A/ja active Pending
- 1995-10-05 BR BR9509308A patent/BR9509308A/pt not_active Application Discontinuation
- 1995-10-05 WO PCT/EP1995/003927 patent/WO1996011924A1/de not_active Ceased
- 1995-10-05 MX MX9702690A patent/MX9702690A/es unknown
- 1995-10-11 US US08/540,987 patent/US5859009A/en not_active Expired - Fee Related
- 1995-10-11 TR TR95/01240A patent/TR199501240A2/xx unknown
- 1995-10-11 IL IL11557195A patent/IL115571A0/xx unknown
- 1995-10-12 ZA ZA958594A patent/ZA958594B/xx unknown
1997
- 1997-04-11 KR KR1019970702364A patent/KR970706278A/ko not_active Withdrawn

Also Published As

Publication number	Publication date
AU3803995A (en)	1996-05-06
KR970706278A (ko)	1997-11-03
TR199501240A2 (tr)	1996-06-21
EP0785934A1 (de)	1997-07-30
MX9702690A (es)	1997-06-28
ZA958594B (en)	1996-05-23
WO1996011924A1 (de)	1996-04-25
BR9509308A (pt)	1997-11-04
IL115571A0 (en)	1996-01-19
DE4436509A1 (de)	1996-04-18
HUT77203A (hu)	1998-03-02
CA2202459A1 (en)	1996-04-25
US5859009A (en)	1999-01-12

Publication	Publication Date	Title
JPH10507187A (ja)	1998-07-14	置換されたスピロアルキルアミノおよびスピロアルコキシ複素環化合物、それらの製法および殺虫剤および殺菌剤としてのそれらの使用
WO1998022446A1 (de)	1998-05-28	Quartaere stickstoff-heterocyclen, verfahren zu ihrer herstellung und ihre verwendung als schädlingsbekämpfungsmittel
JP2000508647A (ja)	2000-07-11	置換されたピリジン／ピリミジン、その製法および殺虫剤としてのその使用
US5691321A (en)	1997-11-25	Heterocyclylamino-and heterocyclyloxy-cycloalkyl derivatives, their preparation, and their use as pesticides and fungicides
AU712903B2 (en)	1999-11-18	Cyclohexylamino and cyclohexylalkoxy nitrogen heterocycles, methods of preparing them and their use as pest-control agents and fungicides
JP2000508636A (ja)	2000-07-11	置換されたピリジン／ピリミジン、その製法および殺虫剤としてのその使用
JP2001504472A (ja)	2001-04-03	第四級窒素複素環式化合物、その製法および農薬としてのその使用
EP0787128A1 (de)	1997-08-06	Substituierte cycloalkylamino- und -alkoxy-heterocyclen, verfahren zu ihrer herstellung und ihre verwendung als schädlingsbekämpfungsmittel
AU704176B2 (en)	1999-04-15	Substituted 1,3-dioxan-5-ylamino heterocyclic compounds, processes for their preparation and their use as pest control compositions
JP2001504124A (ja)	2001-03-27	第四級窒素複素環式化合物、その製法および農薬としてのその使用
JP2002515007A (ja)	2002-05-21	ヘテロシクリル−アミノ−およびヘテロシクリル−オキシ−シクロアルケニル誘導体、害虫防除剤および殺菌剤としてのそれらの使用
US6281221B1 (en)	2001-08-28	Substituted 1,3-dioxan-5-ylamino-hererocyclic compounds, processes for their preparation and their use as pest control compositions
JP2001526659A (ja)	2001-12-18	置換窒素ヘテロ環化合物、その製造方法および農薬としてのその使用