JPH10512956A - 免疫測定法の改良 - Google Patents
免疫測定法の改良Info
- Publication number
- JPH10512956A JPH10512956A JP8522723A JP52272396A JPH10512956A JP H10512956 A JPH10512956 A JP H10512956A JP 8522723 A JP8522723 A JP 8522723A JP 52272396 A JP52272396 A JP 52272396A JP H10512956 A JPH10512956 A JP H10512956A
- Authority
- JP
- Japan
- Prior art keywords
- capture
- solid phase
- signal
- label
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
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- 229960003638 dopamine Drugs 0.000 description 2
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- MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 description 2
- 229960004666 glucagon Drugs 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
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- 239000012948 isocyanate Substances 0.000 description 2
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- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 description 1
- HBEYDAQVMXPRDT-UHFFFAOYSA-N 2-aminoacetic acid;boric acid Chemical compound OB(O)O.NCC(O)=O HBEYDAQVMXPRDT-UHFFFAOYSA-N 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
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- 239000010836 blood and blood product Substances 0.000 description 1
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- 239000011545 carbonate/bicarbonate buffer Substances 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
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- ZFKJVJIDPQDDFY-UHFFFAOYSA-N fluorescamine Chemical compound C12=CC=CC=C2C(=O)OC1(C1=O)OC=C1C1=CC=CC=C1 ZFKJVJIDPQDDFY-UHFFFAOYSA-N 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
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- 230000005855 radiation Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9501416.3 | 1995-01-25 | ||
| GBGB9501416.3A GB9501416D0 (en) | 1995-01-25 | 1995-01-25 | Immunoassay |
| GB9501415.5 | 1995-01-25 | ||
| GBGB9501415.5A GB9501415D0 (en) | 1995-01-25 | 1995-01-25 | Immunoassay |
| GBGB9501622.6A GB9501622D0 (en) | 1995-01-27 | 1995-01-27 | Immunoassay |
| GB9501622.6 | 1995-01-27 | ||
| PCT/GB1996/000152 WO1996023228A1 (fr) | 1995-01-25 | 1996-01-25 | Amelioration d'immuno-essais |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH10512956A true JPH10512956A (ja) | 1998-12-08 |
Family
ID=27267557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8522723A Pending JPH10512956A (ja) | 1995-01-25 | 1996-01-25 | 免疫測定法の改良 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0805982A1 (fr) |
| JP (1) | JPH10512956A (fr) |
| AU (1) | AU4456396A (fr) |
| CA (1) | CA2211322A1 (fr) |
| WO (1) | WO1996023228A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005526950A (ja) * | 2001-07-27 | 2005-09-08 | ロンザ・グループ・アーゲー | 抗体発現細胞を選択する方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4606855A (en) * | 1982-07-26 | 1986-08-19 | Mex Research Associates C/O Leon Reimer | Monoclonal antibody to digoxin |
| GB9211980D0 (en) * | 1992-06-05 | 1992-07-15 | Int Murex Tech Corp | Immunoassay method |
-
1996
- 1996-01-25 EP EP96900665A patent/EP0805982A1/fr not_active Ceased
- 1996-01-25 AU AU44563/96A patent/AU4456396A/en not_active Abandoned
- 1996-01-25 JP JP8522723A patent/JPH10512956A/ja active Pending
- 1996-01-25 CA CA 2211322 patent/CA2211322A1/fr not_active Abandoned
- 1996-01-25 WO PCT/GB1996/000152 patent/WO1996023228A1/fr not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005526950A (ja) * | 2001-07-27 | 2005-09-08 | ロンザ・グループ・アーゲー | 抗体発現細胞を選択する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0805982A1 (fr) | 1997-11-12 |
| CA2211322A1 (fr) | 1996-08-01 |
| AU4456396A (en) | 1996-08-14 |
| WO1996023228A1 (fr) | 1996-08-01 |
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