JPH11240802A - Blood-sucking insect repellent - Google Patents

Abstract

(57) [Problem] To provide a blood sucking insect repellent for indoor space which is excellent in safety and effect. SOLUTION: An indoor air freshener containing nootkatone, valencene or a mixture thereof in an amount of 5% by weight or more.
An aerosol containing 1% by weight or more.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood-sucking pest repellent for indoor space containing nootkatone, valencene or a mixture thereof.

[0002]

2. Description of the Related Art As the typical blood-sucking pests that occur during the summer season, mosquitoes, Aedes albopictus, and Chikae mosquitoes are known. It is widely used. These preparations exhibit effective mosquito repellent by volatilizing the active ingredient in the air by burning or heating, but do not apply heat because such methods involve burning, heating or smoking even at bedtime. (Japanese Patent Laid-Open Publication No. 3-2859593) has been proposed that utilizes a fragrance composition having a mosquito-removing effect, such as a terpene aldehyde containing citral or citronellal, a terpene hydrocarbon containing limonene or terpinene, which is easily vaporized. ).

[0003]

However, the preparation using the above-mentioned fragrance composition having a mosquito-repelling effect has not been satisfactory in mosquito-repelling effect and repellent effect.

[0004]

As a result of various studies on the repellent effect of volatile terpene-based substances on blood-feeding insects, the present inventors have found that valencene and nootkatone, which are found in citrus essential oils and are used in flavors such as beverages, can be used. ,
The present invention has been found to create a space to repel blood-sucking pests and to have a higher repellent effect than diethyltoluamide (DEET), which is a typical repellent in recent years, and a fragrance composition having a mosquito repellent effect, and based on these findings, the present invention. Was completed.

[0005] That is, the present invention provides a blood-sucking insect repellent for indoor space, which contains nootkatone, valencene or a mixture thereof as an active ingredient.

[0006] Nootkatone and valencene used in the present invention are compounds obtained from natural products such as grapefruit oil according to a general method for separating and purifying terpenes.
A compound obtained by organic synthesis or the like can also be used.

The blood-feeding insect repellent of the present invention creates a space for repelling pests such as mosquitoes, and is usually held in a liquid, solid, gel or gaseous carrier.
It is formulated into a room air freshener, aerosol, sheet, paint and the like and applied. The amount of nootkatone, valencene or a mixture thereof in the blood-sucking insect repellent is appropriately determined according to the dosage form and application place, and is not particularly limited, but mosquito repellent by nootkatone, valencen or a mixture thereof is used. The effect depends on air concentration, 0.4μg
/ Cm ³ , and an excellent effect is obtained at 0.7 μg / cm ³ or more.
It is desirable to prepare the preparation so as to be at least μg / cm ³ . In order to obtain such a concentration in the air, for example, 5% by weight or more of an indoor air freshener and 0.1% by weight or more of an aerosol may be mixed with nootkatone, valencene or a mixture thereof. preferable.

The blood-sucking insect repellent of the present invention may contain a pyrethroid-based insecticide such as empentrin, a bactericide, a fungicide, an antioxidant, a coloring agent and various flavor components for flavoring. Can be.

[0009]

EFFECTS OF THE INVENTION The blood-feeding insect repellent according to the present invention can easily create a safe and safe space for repelling blood-feeding insects by having nootkatone, valencene or a mixture thereof at a certain concentration or higher. . Hereinafter, the present invention will be described specifically with reference to Examples and Test Examples,
The present invention is not limited to the following examples.

[0010]

EXAMPLE 1 1 g of nootkatone and 25 g of alcohol were mixed and placed in a pressure-resistant container, and 275 g of propellant was cooled or filled with pressure, and an injection port was attached to obtain an aerosol. The aerosol can be mounted on an automatic spraying device with a timer and used as a regular spraying device.

Example 2 10 g of nootkatone, 60 g of an aqueous 80% alcohol solution and 40 g of 3-methoxy-3-methyl-1-butanol
Was mixed and stirred to obtain a liquid preparation. The liquid was filled in a closed container with a lid, and a rod-shaped liquid absorbing core was inserted into the lid to obtain a liquid indoor fragrance.

Example 3 2 g of carrageenan, 0.5 g of locust bean gum, 5 g of propylene glycol, and 80 g of purified water were mixed and melted by heating, and then 0.1 g of benzalkonium chloride, 0.05 g of indigo carmine and 5 g of nootkatone were melted. In addition, it was transferred to a container and cooled and molded to obtain a solid indoor fragrance.

Example 4 1.5 g of carrageenan, 0.25 g of potassium chloride, 3-
After 15 g of methoxy-3-methyl-1-butanol, 0.1 g of benzethonium chloride and 0.01 g of tartrazine were mixed with 67.14 g of purified water and melted by heating, 6 g of hydrogenated castor oil and 10 g of nootkatone were added and mixed. It was transferred to a container and cooled and molded to obtain a solid indoor fragrance.

Test Example 1 A 10% solution of nootkatone, valencene and a control sample dissolved in alcohol was prepared, and 0.1 ml of the solution was dropped on a filter paper having a diameter of 11 cm (Toyo Filter Paper Co., Ltd.). Next, FIG.
As shown in (2), the wall containing 20 adults of Aedes albopictus is attached to the upper part of a cage (30 cm square) made of a flexible plastic net. The cage has a capacity of 45000cm
Place the mouse in the plastic bag of ^{3 above} , fix the mouse with a wire mesh under the cage, and close the mouth of the plastic bag. After that, the number of mosquitoes flying to blood feeding and their behavior are observed. Also,
Citronella oil and geranium oil of terpene aldehydes known to have a mosquito repellent effect as control samples,
Each of the representative repellents, DEET, was added in the same manner as described above.
The test was performed using filter paper in which 1 ml was dropped. As a blank, filter paper to which only alcohol was dropped was used. 5 in Table 1
And the number of mosquitoes that flew after 10 minutes.

[0015]

[Table 1]

Test Example 2 Volume of 0.5 m connected to three room fragrances of Example 2.
³ Place the test box on the right side of the test box. The mouse fixed with a wire mesh and a cup containing water are put in the left and right test boxes, and 50 cacae turtles are released in the center test box. afterwards,
Observe the number of mosquitoes in each box and their behavior. Further, as control samples, terpene aldehydes citronella oil and geranium oil, which are known to have a mosquito-repelling effect, and DEET, a typical repellent, were tested using indoor fragrances prepared in the same manner as in Example 2. As a blank, a room fragrance prepared only with alcohol was used. Table 2 shows the number of mosquitoes in each test box 1 hour and 4 hours later, and Table 3 shows the total number of mosquitoes that flew to each test box 1 hour after the start of the test.

[0017]

[Table 2]

[0018]

[Table 3]

[Brief description of the drawings]

FIG. 1 illustrates the method of Test Example 1.

Claims (3)

[Claims] 1. A repellent for blood-sucking insects for indoor space, comprising a nootkatone, valencene or a mixture thereof as an active ingredient. 2. An indoor air freshener containing nootkatone, valencene or a mixture thereof in an amount of 5% by weight or more. 3. An aerosol containing nootkatone, valencene or a mixture thereof in an amount of 0.1% by weight or more.