|
US6479055B1
(en)
|
1993-06-07 |
2002-11-12 |
Trimeris, Inc. |
Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
|
|
US6271198B1
(en)
|
1996-11-06 |
2001-08-07 |
Genentech, Inc. |
Constrained helical peptides and methods of making same
|
|
US6841657B2
(en)
|
1997-04-17 |
2005-01-11 |
Whitehead Institute For Biomedical Research |
Inhibitors of HIV membrane fusion
|
|
US6150088A
(en)
|
1997-04-17 |
2000-11-21 |
Whitehead Institute For Biomedical Research |
Core structure of gp41 from the HIV envelope glycoprotein
|
|
US6818740B1
(en)
|
1997-04-17 |
2004-11-16 |
Whitehead Institute For Biomedical Research |
Inhibitors of HIV membrane fusion
|
|
US7960504B2
(en)
|
1998-07-30 |
2011-06-14 |
Whitehead Institute For Biomedical Research |
Inhibitors of HIV membrane fusion
|
|
US6747126B1
(en)
|
1998-07-30 |
2004-06-08 |
Whitehead Institute For Biomedical Research |
Peptide inhibitors of HIV entry
|
|
WO2000066622A1
(en)
|
1999-05-05 |
2000-11-09 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T20/dp178 and t21/dp107 are activators of human phagocyte formyl peptide receptors
|
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
US7053179B2
(en)
|
1999-12-16 |
2006-05-30 |
Whitehead Institute For Biomedical Research |
Five-Helix protein
|
|
AU3334001A
(en)
|
2000-02-10 |
2001-08-20 |
Panacos Pharmaceuticals Inc |
Assay for detection of viral fusion inhibitors
|
|
CA2403718A1
(en)
*
|
2000-03-17 |
2001-09-27 |
Panacos Pharmaceuticals, Inc. |
A method for generating immunogens that elicit neutralizing antibodies against fusion-active regions of hiv envelope proteins
|
|
US20050065319A1
(en)
*
|
2000-12-19 |
2005-03-24 |
Baroudy Bahige M. |
Combination method for treating viral infections
|
|
AU2002314111A1
(en)
|
2001-06-15 |
2003-01-02 |
F. Hoffmann-La Roche Ag |
Method for the recombinant production of peptidic antiviral fusion inhibitors, and acetylation of gb41 fragments
|
|
AU2003210659A1
(en)
*
|
2002-01-24 |
2003-09-02 |
Sangstat Medical Corporation |
Combination therapy for treatment of hiv infection
|
|
CA2500248C
(en)
*
|
2002-09-24 |
2013-03-19 |
Frontier Biotechnologies Co., Ltd. |
Peptide derivative fusion inhibitors of hiv infection
|
|
EP1543166A4
(en)
*
|
2002-09-27 |
2009-10-28 |
Genentech Inc |
SYNERGETIC COMPOSITIONS FOR PREVENTING AND TREATING THE ACQUIRED IMMUNE WEAKNESS SYNDROME
|
|
US7556813B2
(en)
*
|
2002-09-27 |
2009-07-07 |
Trimeris, Inc. |
Antiviral peptide-polymer conjugate comprising a polymer covalently attached to two or more synthetic HIV gp41 HR1 and/or HR2 peptides
|
|
MXPA05007016A
(es)
|
2003-01-14 |
2005-09-12 |
Gilead Sciences Inc |
Composiciones y metodos para terapia antiviral de combinacion.
|
|
PT1624891E
(pt)
|
2003-05-06 |
2010-01-05 |
Syntonix Pharmaceuticals Inc |
Proteínas quiméricas de factor de coagulação-fc destinadas ao tratamento da hemofilia
|
|
CA2522690A1
(en)
*
|
2003-05-06 |
2004-11-25 |
Syntonix Pharmaceuticals, Inc. |
Inhibition of drug binding to serum albumin
|
|
TWI353991B
(en)
*
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
WO2004108885A2
(en)
*
|
2003-05-06 |
2004-12-16 |
Syntonix Pharmaceuticals, Inc. |
Fc chimeric proteins with anti-hiv drugs
|
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
EP2161027A3
(en)
*
|
2003-12-22 |
2010-04-28 |
Yeda Research And Development Co., Ltd. |
Diastereomeric peptides useful as inhibitors of membrane protein assembly
|
|
BRPI0418304A
(pt)
*
|
2004-01-07 |
2007-05-02 |
Trimeris Inc |
peptìdeo sintético, uso do mesmo, composição farmacêutica, seqüência de nucleotìdeos, e, métodos para inibição da transmissão de hiv para uma célula, para inibição da fusão de hiv, e para tratamento de um indivìduo infectado com hiv
|
|
EP1755667B1
(en)
|
2004-06-01 |
2013-07-17 |
Merck Sharp & Dohme Corp. |
Stable peptide mimetic of hiv gp41 fusion intermediate
|
|
US20060154895A1
(en)
*
|
2004-12-09 |
2006-07-13 |
Maxwell Gordon |
Method of treating acquired immunedeficiency syndrome
|
|
GB0501352D0
(en)
*
|
2005-01-21 |
2005-03-02 |
Slingsby Jason H |
Use of glycosylation modulators in combination with membrane fusion inhibitors for treatment of infections caused by viruses bearing glycosylated envelope
|
|
CA2602654A1
(en)
*
|
2005-04-05 |
2006-10-12 |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
Method for shielding functional sites or epitopes on proteins
|
|
US7456251B2
(en)
*
|
2006-02-02 |
2008-11-25 |
Trimeris, Inc. |
HIV fusion inhibitor peptides with improved biological properties
|
|
EP1886696A1
(en)
*
|
2006-08-03 |
2008-02-13 |
Endotis Pharma |
Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins
|
|
AU2007286451A1
(en)
|
2006-08-17 |
2008-02-21 |
F. Hoffmann-La Roche Ag |
A conjugate of an antibody against CCR5 and an antifusogenic peptide
|
|
TW200817438A
(en)
|
2006-08-17 |
2008-04-16 |
Hoffmann La Roche |
A conjugate of an antibody against CCR5 and an antifusogenic peptide
|
|
CN101622274A
(zh)
|
2006-12-12 |
2010-01-06 |
比奥雷克西斯药物公司 |
转铁蛋白融合蛋白库
|
|
CL2008000707A1
(es)
|
2007-03-13 |
2008-09-22 |
Hoffmann La Roche |
Conjugado de polipeptidos antifusogenicos y polipeptidos derivados de la cabeza globular del factor del complemento c1q; composicion farmaceutica que lo comprende; su uso para tratar infecciones viricas; y metodo de produccion.
|
|
BRPI0809995A2
(pt)
*
|
2007-04-03 |
2015-07-21 |
Trimeris Inc |
Composição, e, métodos para a liberação prolongada de um peptídeo em um paciente e para melhorar um sintoma associado com uma infecção por hiv
|
|
US20090022720A1
(en)
|
2007-07-20 |
2009-01-22 |
Stephan Fischer |
Conjugate of an antibody against CD4 and antifusogenic peptides
|
|
KR20100080812A
(ko)
*
|
2007-09-25 |
2010-07-12 |
트라이머리스, 인코퍼레이티드 |
치료용 항-hiv 펩티드의 합성 방법
|
|
CA2797033C
(en)
|
2010-04-22 |
2021-10-19 |
Longevity Biotech, Inc. |
Highly active polypeptides and methods of making and using the same
|
|
RU2013113723A
(ru)
|
2010-09-14 |
2014-10-20 |
Ф.Хоффманн-Ля Рош Аг |
Гибридный полипептид с серпиновым "пальцем"
|
|
TWI577377B
(zh)
|
2010-09-16 |
2017-04-11 |
Viiv醫療保健公司 |
醫藥組合物
|
|
CN103974971B
(zh)
*
|
2012-02-28 |
2016-09-14 |
中国人民解放军军事医学科学院毒物药物研究所 |
用于抑制hiv的多肽、其药物组合物及其用途
|
|
AR095527A1
(es)
|
2013-03-15 |
2015-10-21 |
Biogen Idec Inc |
Formulaciones de polipéptido fc-factor ix
|
|
US9789164B2
(en)
|
2013-03-15 |
2017-10-17 |
Longevity Biotech, Inc. |
Peptides comprising non-natural amino acids and methods of making and using the same
|
|
WO2018002902A1
(en)
|
2016-07-01 |
2018-01-04 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Antibody-drug conjugates and therapeutic methods using the same
|