|
US6479055B1
(en)
|
1993-06-07 |
2002-11-12 |
Trimeris, Inc. |
Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
|
|
US6271198B1
(en)
|
1996-11-06 |
2001-08-07 |
Genentech, Inc. |
Constrained helical peptides and methods of making same
|
|
US6841657B2
(en)
|
1997-04-17 |
2005-01-11 |
Whitehead Institute For Biomedical Research |
Inhibitors of HIV membrane fusion
|
|
US6150088A
(en)
|
1997-04-17 |
2000-11-21 |
Whitehead Institute For Biomedical Research |
Core structure of gp41 from the HIV envelope glycoprotein
|
|
US6818740B1
(en)
|
1997-04-17 |
2004-11-16 |
Whitehead Institute For Biomedical Research |
Inhibitors of HIV membrane fusion
|
|
US7960504B2
(en)
|
1998-07-30 |
2011-06-14 |
Whitehead Institute For Biomedical Research |
Inhibitors of HIV membrane fusion
|
|
US6747126B1
(en)
|
1998-07-30 |
2004-06-08 |
Whitehead Institute For Biomedical Research |
Peptide inhibitors of HIV entry
|
|
AU4988900A
(en)
|
1999-05-05 |
2000-11-17 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
T20/dp178 and t21/dp107 are activators of human phagocyte formyl peptide receptors
|
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
CA2395291C
(en)
|
1999-12-16 |
2012-09-11 |
Whitehead Institute For Biomedical Research |
Five-helix protein
|
|
EP1264177A2
(en)
|
2000-02-10 |
2002-12-11 |
Panacos Pharmaceuticals, Inc. |
Assay for detection of viral fusion inhibitors
|
|
NZ521977A
(en)
*
|
2000-03-17 |
2004-05-28 |
Panacos Pharmaceuticals Inc |
A method for generating immunogens that elicit neutralizing antibodies against fusion-active regions of HIV envelope proteins
|
|
US20050065319A1
(en)
*
|
2000-12-19 |
2005-03-24 |
Baroudy Bahige M. |
Combination method for treating viral infections
|
|
CA2450548C
(en)
|
2001-06-15 |
2012-05-01 |
F. Hoffmann-La Roche Ag |
Method for the recombinant production of peptidic antiviral fusion inhibitors, and acetylation of gb41 fragments
|
|
US7094413B2
(en)
*
|
2002-01-24 |
2006-08-22 |
Sangstat Medical Corporation |
Combined therapy for treatment of HIV infection
|
|
AU2003275116A1
(en)
|
2002-09-24 |
2004-04-19 |
Frontier Biotechnologies Co., Ltd |
Peptide derivative fusion inhibitors of hiv infection
|
|
US7556813B2
(en)
*
|
2002-09-27 |
2009-07-07 |
Trimeris, Inc. |
Antiviral peptide-polymer conjugate comprising a polymer covalently attached to two or more synthetic HIV gp41 HR1 and/or HR2 peptides
|
|
EP1543166A4
(en)
*
|
2002-09-27 |
2009-10-28 |
Genentech Inc |
SYNERGETIC COMPOSITIONS FOR PREVENTING AND TREATING THE ACQUIRED IMMUNE WEAKNESS SYNDROME
|
|
EA015145B1
(ru)
|
2003-01-14 |
2011-06-30 |
Джилид Сайэнс, Инк. |
Фармацевтическая композиция и пероральная фармацевтическая дозированная форма (варианты), проявляющие активность в отношении вич-инфекций, лечебный набор и таблетка и способ лечения или предотвращения симптомов или эффектов вич-инфекции
|
|
WO2004108885A2
(en)
*
|
2003-05-06 |
2004-12-16 |
Syntonix Pharmaceuticals, Inc. |
Fc chimeric proteins with anti-hiv drugs
|
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
ES2333598T5
(es)
*
|
2003-05-06 |
2013-09-04 |
Biogen Idec Hemophilia Inc |
Proteinas quimericas del factor de coagulacion fc para tratar la hemofilia.
|
|
AU2004238263A1
(en)
*
|
2003-05-06 |
2004-11-25 |
Syntonix Pharmaceuticals, Inc. |
Inhibition of drug binding to serum albumin
|
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
US20080096809A1
(en)
*
|
2003-12-22 |
2008-04-24 |
Yeda Research & Development Co. Ltd. |
Diastereomeric Peptides Useful as Inhibitors of Membrane Protein Assembly
|
|
JP2007517522A
(ja)
*
|
2004-01-07 |
2007-07-05 |
トリメリス,インコーポレーテッド |
HIVgp41HR2由来の合成ペプチド、およびヒト免疫不全ウイルスの伝播を阻止する治療におけるその使用
|
|
EP2354153A3
(en)
|
2004-06-01 |
2012-05-30 |
Merck Sharp & Dohme Corp. |
Stable peptide mimetic of HIV gp41 fusion intermediate
|
|
US20060154895A1
(en)
*
|
2004-12-09 |
2006-07-13 |
Maxwell Gordon |
Method of treating acquired immunedeficiency syndrome
|
|
GB0501352D0
(en)
*
|
2005-01-21 |
2005-03-02 |
Slingsby Jason H |
Use of glycosylation modulators in combination with membrane fusion inhibitors for treatment of infections caused by viruses bearing glycosylated envelope
|
|
EP2314320A2
(en)
*
|
2005-04-05 |
2011-04-27 |
Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. |
Method for shielding functional sites or epitopes on proteins
|
|
EP1989220B1
(en)
|
2006-02-02 |
2011-12-14 |
Trimeris, Inc. |
Hiv fusion inhibitor peptides with improved biological properties
|
|
EP1886696A1
(en)
*
|
2006-08-03 |
2008-02-13 |
Endotis Pharma |
Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins
|
|
TW200817438A
(en)
|
2006-08-17 |
2008-04-16 |
Hoffmann La Roche |
A conjugate of an antibody against CCR5 and an antifusogenic peptide
|
|
KR101105610B1
(ko)
|
2006-08-17 |
2012-01-18 |
에프. 호프만-라 로슈 아게 |
Ccr5 에 대한 항체 및 항푸소제닉 펩타이드의 컨쥬게이트
|
|
ES2535358T3
(es)
|
2006-12-12 |
2015-05-08 |
Biorexis Pharmaceutical Corporation |
Bibliotecas de proteínas de fusión de transferrina
|
|
CL2008000707A1
(es)
*
|
2007-03-13 |
2008-09-22 |
Hoffmann La Roche |
Conjugado de polipeptidos antifusogenicos y polipeptidos derivados de la cabeza globular del factor del complemento c1q; composicion farmaceutica que lo comprende; su uso para tratar infecciones viricas; y metodo de produccion.
|
|
BRPI0809995A2
(pt)
*
|
2007-04-03 |
2015-07-21 |
Trimeris Inc |
Composição, e, métodos para a liberação prolongada de um peptídeo em um paciente e para melhorar um sintoma associado com uma infecção por hiv
|
|
US20090022720A1
(en)
|
2007-07-20 |
2009-01-22 |
Stephan Fischer |
Conjugate of an antibody against CD4 and antifusogenic peptides
|
|
BRPI0817697A2
(pt)
*
|
2007-09-25 |
2015-04-07 |
Trimeris Inc |
Método de síntese de um peptídeo, conjunto de fragmentos de peptídeo, e, peptídeo
|
|
US9782454B2
(en)
|
2010-04-22 |
2017-10-10 |
Longevity Biotech, Inc. |
Highly active polypeptides and methods of making and using the same
|
|
JP5757639B2
(ja)
|
2010-09-14 |
2015-07-29 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
セルピンフィンガー融合ポリペプチド
|
|
TWI577377B
(zh)
|
2010-09-16 |
2017-04-11 |
Viiv醫療保健公司 |
醫藥組合物
|
|
CN103974971B
(zh)
*
|
2012-02-28 |
2016-09-14 |
中国人民解放军军事医学科学院毒物药物研究所 |
用于抑制hiv的多肽、其药物组合物及其用途
|
|
WO2014145718A2
(en)
|
2013-03-15 |
2014-09-18 |
Longevity Biotech, Inc. |
Peptides comprising non-natural amino acids and methods of making and using the same
|
|
TWI828269B
(zh)
|
2013-03-15 |
2024-01-01 |
美商百歐維拉提夫治療公司 |
因子ix多肽調配物
|
|
JP2019524687A
(ja)
|
2016-07-01 |
2019-09-05 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
抗体薬物複合体およびこれを用いた治療方法
|