|
IT1278077B1
(it)
|
1995-05-25 |
1997-11-17 |
Angeletti P Ist Richerche Bio |
Metodologia per riprodurre in vitro le attivita' di rna polimerasi rna-dipendente e di nucleotidiltransferasi terminale codificate dal
|
|
FR2761695B1
(fr)
|
1997-04-04 |
1999-09-24 |
Bio Merieux |
Arn polymerase fonctionnant preferentiellement sur matrice d'arn, sa preparation et son utilisation
|
|
DE69838513T2
(de)
*
|
1997-12-11 |
2008-07-03 |
Smithkline Beecham Corp. |
Verkürztes hepatitis-c-virus protein nsb5 und methoden, um antivirale substanzen zu identifizieren
|
|
EP1058686B1
(en)
|
1998-02-25 |
2006-11-02 |
Emory University |
2'-fluoronucleosides
|
|
EP1068362A4
(en)
*
|
1998-04-02 |
2005-07-20 |
Viropharma Inc |
HEPATITIS C VIRUS NS5B COMPOSITIONS AND METHOD FOR THEIR USE
|
|
AU4393399A
(en)
*
|
1998-06-24 |
2000-01-10 |
Chugai Seiyaku Kabushiki Kaisha |
Hcv-derived rna polymerase gene
|
|
AU2181800A
(en)
*
|
1998-12-10 |
2000-06-26 |
Eli Lilly And Company |
Primer-independent rna synthesis catalyzed by hcv polymerase
|
|
EP1634888A3
(en)
|
1999-11-12 |
2007-11-21 |
Pharmasset, Inc. |
Synthesis of 2'-deoxy-L-nucleosides
|
|
AU764095B2
(en)
*
|
2000-04-07 |
2003-08-07 |
Shionogi & Co., Ltd. |
Preincubation assay method
|
|
PY0111577A
(es)
|
2000-05-23 |
2017-01-02 |
Idenix Cayman Ltd |
Métodos y composiciones para el tratamiento del virus de la hepatitis c
|
|
AP2006003708A0
(en)
|
2000-05-26 |
2006-08-31 |
Idenix Cayman Ltd |
Methods and compositions for treating flavivirusesand pestiviruses
|
|
GB0029539D0
(en)
*
|
2000-12-04 |
2001-01-17 |
Isis Innovation |
Method for identifying modulatorss of transcription
|
|
EP1360276A4
(en)
*
|
2001-01-31 |
2004-12-15 |
Bristol Myers Squibb Pharma Co |
IN VITRO SYSTEM FOR REPLICATION OF RNA-DEPENDENT RNA POLYMERASE VIRUSES
|
|
WO2002095002A2
(en)
*
|
2001-05-22 |
2002-11-28 |
University Of Chicago |
N4 virion single-stranded dna dependent rna polymerase
|
|
CA2460819A1
(en)
*
|
2001-09-18 |
2003-03-27 |
Affinium Pharmaceuticals, Inc. |
Methods and apparatuses for purification
|
|
WO2003027330A1
(en)
*
|
2001-09-25 |
2003-04-03 |
Xencor |
Rna dependent rna polymerase mediated protein evolution
|
|
AU2002330154A1
(en)
|
2001-09-28 |
2003-04-07 |
Centre National De La Recherche Scientifique |
Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
|
|
KR100447578B1
(ko)
*
|
2001-11-01 |
2004-09-07 |
주식회사 이매진 |
Ｈｃｖ 자가 복제 효소 활성의 세포내 측정용 키트 및측정 방법
|
|
WO2003044168A2
(en)
*
|
2001-11-16 |
2003-05-30 |
University Of Massachusetts |
Facilitation of rna interference
|
|
PT1523489E
(pt)
|
2002-06-28 |
2014-06-24 |
Centre Nat Rech Scient |
Profármacos de nucleósido modificado em 2' e 3' para tratamento de infecções por flaviridae
|
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
RU2005118421A
(ru)
|
2002-11-15 |
2006-01-20 |
Айденикс (Кайман) Лимитед (Ky) |
2'-разветвленные нуклеозиды и мутация flaviviridae
|
|
BRPI0419345B8
(pt)
|
2003-05-30 |
2021-05-25 |
Gilead Pharmasset Llc |
uso do (2r)-2-desoxi-2-flúor-2-c-metil nucleosídeo e de uma composição farmacêutica que o compreende
|
|
DK1658302T3
(da)
|
2003-07-25 |
2010-11-22 |
Idenix Pharmaceuticals Inc |
Purinnukleosidanaloge til behandling af sygdomme forårsaget af Flavirividae, herunder hepatitis C
|
|
EP1711516A4
(en)
*
|
2004-01-09 |
2009-12-30 |
Merck & Co Inc |
HCV RNA-dependent RNA polymerase
|
|
WO2006121468A1
(en)
|
2004-11-22 |
2006-11-16 |
Genelabs Technologies, Inc. |
5-nitro-nucleoside compounds for treating viral infections
|
|
BRPI0607770A2
(pt)
|
2005-02-28 |
2009-06-13 |
Genelabs Tech Inc |
compostos de nucleosideo tricìclico para tratamento de infecções virais
|
|
TW200720285A
(en)
|
2005-04-25 |
2007-06-01 |
Genelabs Tech Inc |
Nucleoside compounds for treating viral infections
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
US20090318380A1
(en)
|
2007-11-20 |
2009-12-24 |
Pharmasset, Inc. |
2',4'-substituted nucleosides as antiviral agents
|
|
WO2010014134A1
(en)
|
2008-07-02 |
2010-02-04 |
Idenix Pharamaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2166016A1
(en)
|
2008-09-18 |
2010-03-24 |
Centocor Ortho Biotech Products L.P. |
Phosphoramidate Derivatives of Nucleosides
|
|
TW201026715A
(en)
|
2008-12-23 |
2010-07-16 |
Pharmasset Inc |
Nucleoside phosphoramidates
|
|
JP6104504B2
(ja)
|
2008-12-23 |
2017-03-29 |
ギリアド ファーマセット エルエルシー |
ヌクレオシド類似体
|
|
CL2009002206A1
(es)
|
2008-12-23 |
2011-08-26 |
Gilead Pharmasset Llc |
Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
TWI583692B
(zh)
|
2009-05-20 |
2017-05-21 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
WO2011023801A1
(en)
|
2009-08-31 |
2011-03-03 |
F. Hoffmann-La Roche Ag |
Hcv ns3/4a replicon shuttle vectors
|
|
BR112012011221A2
(pt)
|
2009-11-14 |
2016-04-05 |
Hoffmann La Roche |
biomarcadores para prever resposta rápida ao tratamento de hcv
|
|
CN102656459A
(zh)
|
2009-12-02 |
2012-09-05 |
弗·哈夫曼-拉罗切有限公司 |
用于预测对hcv治疗持续应答的生物标志物
|
|
US20110245328A1
(en)
|
2010-03-31 |
2011-10-06 |
Hyunsoon Kang |
HCV NS5A Replicon Shuttle Vectors
|
|
CL2011000716A1
(es)
|
2010-03-31 |
2012-04-20 |
Gilead Pharmasset Llc |
Formas cristalinas 1 6 de (s)-isopropil-2-(((s)-(((2r.3r.4r.5r)-5-(2,4-dioxo-3,4-dihidropirimidin-1(2h)-il)-4-fluoro-3-hidroxi-4-metil tetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato; composicion y combinacion farmaceutica; y su uso para tratar una infeccion por el virus de la hepatitis c.
|
|
UY33312A
(es)
|
2010-03-31 |
2011-10-31 |
Pharmasset Inc |
Fosforamidato de nucleosido de purina
|
|
TWI515000B
(zh)
|
2010-04-01 |
2016-01-01 |
伊迪尼克製藥公司 |
用於治療病毒感染之化合物及醫藥組合物
|
|
US8324239B2
(en)
|
2010-04-21 |
2012-12-04 |
Novartis Ag |
Furopyridine compounds and uses thereof
|
|
AU2011281546B2
(en)
|
2010-07-22 |
2014-07-10 |
Novartis Ag |
2,3,5-trisubstituted thiophene compounds and uses thereof
|
|
WO2012075140A1
(en)
|
2010-11-30 |
2012-06-07 |
Pharmasset, Inc. |
Compounds
|
|
EP2658857B1
(en)
|
2010-12-29 |
2016-11-02 |
Inhibitex, Inc. |
Substituted purine nucleosides, phosphoroamidate and phosphorodiamidate derivatives for treatment of viral infections
|
|
CN103842369A
(zh)
|
2011-03-31 |
2014-06-04 |
埃迪尼克斯医药公司 |
用于治疗病毒感染的化合物和药物组合物
|
|
AR088441A1
(es)
|
2011-09-12 |
2014-06-11 |
Idenix Pharmaceuticals Inc |
Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
WO2013039855A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
TW201331221A
(zh)
|
2011-10-14 |
2013-08-01 |
Idenix Pharmaceuticals Inc |
嘌呤核苷酸化合物類之經取代的３’，５’－環磷酸酯及用於治療病毒感染之醫藥組成物
|
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
|
JP2016529293A
(ja)
|
2013-08-27 |
2016-09-23 |
ギリアド ファーマセット エルエルシー |
２つの抗ウイルス化合物の組合せ製剤
|