JPS5525409A - Novel 1*33glucan* its preparation and use - Google Patents
Novel 1*33glucan* its preparation and useInfo
- Publication number
- JPS5525409A JPS5525409A JP9728578A JP9728578A JPS5525409A JP S5525409 A JPS5525409 A JP S5525409A JP 9728578 A JP9728578 A JP 9728578A JP 9728578 A JP9728578 A JP 9728578A JP S5525409 A JPS5525409 A JP S5525409A
- Authority
- JP
- Japan
- Prior art keywords
- basis
- water
- glucopyranose
- insoluble part
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
NEW MATERIAL:A compound having a main chain containing β-1,3-gluco-pyranose I (Glu is glucopyranose residual group) as the recurrent unit, and side chains II (n is 0W2; R is the group derived from β-D-glucopyranose III) or both II and IV. Preferable example is a compound having 20W80 side chanis II and 0W30 side chains IV on the basis of 100 glucopyranose units.
USE: Remedy for tumor. Excellent in suppressing effect for solid tumor.
PREPARATION: The fruit body or mycelium of the Jew's-ear fungi is extracted with 1W30 time volume of an aqueous medium to obtain the insoluble part. The insoluble part is washed with water, oxidized with periodic acid or its water-soluble salt (0.01W0.5M on the basis of the insoluble part), and further reduced with a water- soluble reducing agent (about equimolar amount on the basis of periodic acid). If desired, the product is hydrolyzed preferably with a 0.01W0.2N acid at the lowest possible temperature for 10W24hr, followed by separation and extraction.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP53097285A JPS5840477B2 (en) | 1978-08-11 | 1978-08-11 | Novel β-1,3-glucan, its production method and use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP53097285A JPS5840477B2 (en) | 1978-08-11 | 1978-08-11 | Novel β-1,3-glucan, its production method and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5525409A true JPS5525409A (en) | 1980-02-23 |
| JPS5840477B2 JPS5840477B2 (en) | 1983-09-06 |
Family
ID=14188232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53097285A Expired JPS5840477B2 (en) | 1978-08-11 | 1978-08-11 | Novel β-1,3-glucan, its production method and use |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5840477B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019502652A (en) * | 2015-10-26 | 2019-01-31 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Reduced and oxidized polysaccharides and methods of their use |
-
1978
- 1978-08-11 JP JP53097285A patent/JPS5840477B2/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019502652A (en) * | 2015-10-26 | 2019-01-31 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Reduced and oxidized polysaccharides and methods of their use |
| JP2022046645A (en) * | 2015-10-26 | 2022-03-23 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Reduced and oxidized polysaccharides and methods of their use |
| US11771767B2 (en) | 2015-10-26 | 2023-10-03 | President And Fellows Of Harvard College | Reduced and oxidized polysaccharides and methods of use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5840477B2 (en) | 1983-09-06 |
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